The Community-based Genetic Screening Research program under Dr. Henry Lynch’s research and clinical program will gather familial/hereditary cancer-prone histories from African Americans in Omaha, NE; and combine their clinical and molecular findings for better insight into the natural history and pathogenesis of their cancers. The goal is to significantly contribute to the ultimate control of these cancers. Educational and research interventions will focus on hereditary breast, colon and familial prostate cancer. Biostatistical analysis to study screening input, management, and mortality rates will be compared to determine the effects of educational interventions over a 5 year period. The community based participatory research model will enhance the opportunity of generation of data and ultimately glean clearer understanding of the scientific results that could benefit AAs to reduce cancer mortality and provide greater insight into the factors that could be related to differences in treatment, socio-economically, racial disparity, and environmental/lifestyle factors.
This research on hereditary cancer is abetted by more than 750 peer-reviewed publications on the subject. In addition, Dr. lynch has provided hundreds of lectures and helped organize centers of hereditary cancer expertise throughout the world.