A. Joseph Threlkeld, Ph.D., associate professor of physical therapy and director of the Rehabilitation Science Research Laboratory, Creighton University, has received a two-year $360,981 grant from the National Institutes of Health (NIH) to study the causes of fatigue in people with Parkinson’s disease. This is the second NIH grant awarded to Threlkeld and the fourth NIH grant awarded to the investigative team in the laboratory to study the neuromuscular effects of Parkinson’s disease.
Dr. Threlkeld’s research will focus on an effort to differentiate fatigue of the quadriceps muscle (peripheral fatigue) in persons with Parkinson’s disease from the type of fatigue that originates from the central nervous system (central fatigue). Increased fatigability is one of the top three disabling symptoms for the majority of persons with Parkinson’s disease. The results may provide insights that will improve treatments for persons with fatigue caused by Parkinson’s disease.
The research project incorporates a multidisciplinary team of co-investigators from the Creighton School of Pharmacy and Health Professions.
Dr. Threlkeld earned his undergraduate degree in physical therapy and a doctorate in human anatomy from the University of Kentucky. A Creighton faculty member since 1992, he was one of the founding faculty members of the Creighton physical therapy program which developed the first entry-level doctoral degree for physical therapists.
A member of the American Physical Therapy Association (APTA) since 1974, Dr. Threlkeld is active in several APTA specialty groups. He is also a member of the American Association of Clinical Anatomists, American Society of Biomechanics and the Gait and Clinical Motion Analysis Society. He sits on the editorial board of “Physical Therapy Reviews” and is an article reviewer for “Physical Therapy,” “The Journal of Orthopedic and Sports Physical Therapy,” “The Archives of Physical Medicine and Rehabilitation,” “Clinical Anatomy,” “Neuroscience Letters” and the “Journal of Applied Physiology.”