Gamma Delta Pi was born on August 27, 2001 on the campus of the University of Oklahoma in Norman, Oklahoma. Gamma Delta Pi was founded by five college women, known as the Five Changing Women: Jennifer Nez (Navajo), Sedelta Oosahwee (Cherokee/Mandan/Arikara/Hidatsa), Joyce Shield (Comanche/Osage/Chippewa-Cree), Robin Williams (Kiowa/Apache/Nez Perce/Assinaboine Sioux/Umatilla), and Shema Yearby (Seminole/Creek/Mississippi Choctaw). In the fall of 2001, the Five Changing Women presented the idea of creating a sisterhood based solely to carry on the ideals, culture, tradition, and legacy of American Indian women.
On August 19, 2006 Gamma Delta Pi expanded its roots to a Beta Chapter at Creighton University in Omaha, Nebraska. The four founders of the Beta Chapter include: Donnel Ecoffey (Lakota), Cedora Barnett (Omaha), Keshia Bradford (Blackfoot), and Maria Chagolla.
Gamma Delta Pi is an organization open to women matriculated in any college or university who meet the requirements of Gamma Delta Pi and who are committed to creating a life-long bond among sisters while instilling character, an appreciation of the native culture, unity, respect, scholarship, and most importantly, the sisterhood of Native American women.