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Tejbeer Kaur, PhD

Assistant Professor

Biomedical Sciences

Tejbeer Kaur

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School of Medicine
Biomedical Sciences
Graduate School
Biomedical Sciences (Doctorate)
Biomedical Sciences (Master of Science)
CRISS I - Criss 1

Tejbeer Kaur, PhD

Assistant Professor

Biomedical Sciences

BS: Pharmacy, University of Delhi, India, 2005
MS: Pharmacology, University of Delhi, India,  2008
PhD: Pharmacology, Southern Illinois University, Carbondale, IL, 2012
Postdoctoral Research: Auditory Neurobiology, Washington University, St. Louis, MO, 2016

 

Teaching Interests

  • Auditory Neuroscience

Research Focus

To understand the biological mechanisms of neuron degeneration and their endogenous repair and survival in the mammalian auditory system with a long-term goal to develop therapies to preserve or restore hearing.

Department

Biomedical Sciences

Position

Assistant Professor

Articles

  • Frontiers in Cell and Developmental Biology
    Borse, Vikrant, Programmed Cell Death Recruits Macrophages Into the Developing Mouse Cochlea AUTHOR=Borse Vikrant, Kaur Tejbeer, Hinton Ashley, Ohlemiller Kevin, Warchol Mark E. DOI=10.3389/fcell.2021.777836
    9 2021
  • Frontiers in Cellular Neuroscience
    Andrew Stothert and Tejbeer Kaur, Innate Immunity to Spiral Ganglion Neuron Loss: A Neuroprotective Role of Fractalkine Signaling in Injured Cochlea in the journal of Frontiers in Cellular Neuroscience. DOI: https://doi.org/10.3389/fncel.2021.694292 2021
  • Scientific Reports
    , Borse V, Barton M, Arndt H, Kaur T, Warchol ME. Dynamic patterns of YAP1 expression and cellular localization in the developing and injured utricle. Sci Rep. 2021 Jan 25;11(1):2140. doi: 10.1038/s41598-020-77775-8. PMID: 33495483; PMCID: PMC7835353. 2021
  • Frontiers in Neuroscience
    Kaur T, Clayman AC, Nash AJ, Schrader AD, Warchol ME, Ohlemiller KK. Lack of Fractalkine Receptor on Macrophages Impairs Spontaneous Recovery of Ribbon Synapses After Moderate Noise Trauma in C57BL/6 Mice. 
    13:620 2019
  • Journal of Comparative Neurology
    Kaur T, Ohlemiller KK, Warchol ME. Genetic disruption of fractalkine signaling leads to enhanced loss of cochlear afferents following ototoxic or acoustic injury. 
    526 (5), p. 824-835 2018
  • Hearing Research
    Ohlemiller KK, Kaur T, Warchol ME, Withnell RH. The endocochlear potential as an indicator of reticular lamina integrity after noise exposure in mice.*Selected for Journal Cover Page 
    361, p. 138-151 2018
  • Journal of neuroscience : the official journal of the Society for Neuroscience
    , Kaur T, Borse V, Sheth S, Sheehan K, Ghosh S, Tupal S, Jajoo S, Mukherjea D, Rybak LP, Ramkumar V. Adenosine A1 Receptor Protects Against Cisplatin Ototoxicity by Suppressing the NOX3/STAT1 Inflammatory Pathway in the Cochlea.
    36 (14), p. 3962-3977 2016
  • Journal of neuroscience : the official journal of the Society for Neuroscience
    , Kaur T, Zamani D, Tong L, Rubel EW, Ohlemiller KK, Hirose K, Warchol ME. Fractalkine signaling regulates macrophage recruitment into the cochlea and promotes the survival of spiral ganglion neurons after selective hair cell lesion.
    35 (45), p. 15050-15061 2015
  • Journal of neuroscience : the official journal of the Society for Neuroscience
    , Tong L, Strong MK, Kaur T, Juiz JM, Oesterle EC, Hume C, Warchol ME, Palmiter RD, Rubel EW.Selective deletion of cochlear hair cells causes rapid age-dependent changes in spiral ganglion and cochlear nucleus neurons.
    35 (20), p. 7878-7891 2015
  • Frontiers in Cellular Neuroscience
    Kaur T, Hirose K, Rubel EW, Warchol ME. Macrophage recruitment and epithelial repair following hair cell injury in the mouse utricle.
    9:150 2015

Presentations

  • 3rd Annual Bellucci Symposium on Hearing Research. Poster: Fate mapping reveals slow turnover of adult cochlear macrophages in steady state and distinguishes resident from recruited monocyte-derived macrophages following acoustic trauma. Presented by Andrew Stothert (postdoc Fellow) 2021
  • Symposium on Neuro-Immune Interactions. Poster Presentation: Fate mapping reveals slow turnover of adult cochlear macrophages in steady state and distinguishes resident from recruited monocyte-derived macrophages following acoustic trauma. Presented by: Andrew Stothert (postdoc fellow) 2021
  • ARO 44th MidWinter Meeting (virtual, national): Talk: Macrophages facilitate repair of damaged ribbon synapses after acoustic trauma. Presented by Tejbeer Kaur Poster: Fate mapping reveals slow turnover of adult cochlear macrophages in steady state and distinguishes resident from recruited monocyte-derived macrophages following acoustic trauma.Presented by Andrew Stothert (Postdoc Fellow) 2021
  • Mihai Stancu, Ezhilarasan Rajaram, Hilde Wohlfrom, Tejbeer Kaur, Mark Warchol, Edwin W Rubel and Conny Kopp-Scheinpflug. Modulations of neural action potential rates can influence electrical properties of oligodendrocytes and myelination of individual trapezoid body axons. ARO 43rd Midwinter research meeting, January 25-29, 2020, San Jose, California.  2020
  • Anna C. Clayman, Kevin K. Ohlemiller, Mark E. Warchol, Tejbeer Kaur. Lack of Macrophages Impair Spontaneous Repair of Ribbon Synapses After Synaptopathic Acoustic Trauma in C57BL/6 mice.ARO 43rd Midwinter research meeting, January 25-29, 2020, San Jose, California.  2020
  • Van A. Redila, Ling Tong, Robin M. Gibson, Tejbeer Kaur, Mark E. Warchol, Edwin W Rubel. Influence of Macrophages and Microglia on Spiral Ganglion and Cochlear Nucleus Neuron Survival Following Selective Hair Cell Death in Mature Mice.ARO 43rd Midwinter research meeting, January 25-29, 2020, San Jose, California.  2020
  • Tejbeer Kaur, Anna Clayman, Andrew Nash, Mark E. Warchol and Kevin K. Ohlemiller. Macrophage Regulates Ribbon Synapse Repair and Neuron Survival Via Fractalkine Signaling After Noise-Induced Cochlear Synaptopathy.  Midwest Auditory Research Conference (MARC), July 11-13, 2019, Springfield, Illinois. (*oral presentation)  2019
  • Tejbeer Kaur, Erik Tycksen, Mark E. Warchol, Mike Heinz. Differential Gene Expression in FACS Sorted Mature Cochlear Neurons and Macrophages After Selective Hair Cell Ablation. ARO 42nd Midwinter research meeting, February 9-13, 2019, Baltimore, Maryland.  2019

Federal

  • R03 DC015320 NIH/NIDCD
    Period: 04/2016 – 07/2019
    Role: PI
    $450,000 (total)
    Role of macrophages in noise-induced cochlear synaptopathy and neuropathy.

Awards

  • Co-Chair
    Serve as Co-Chair for the Young Investigator Symposia proposal titled, “Role of Immune Cells in the Auditory System Development, Pathology and Regeneration”, at the ARO 44th Annual Midwinter Meeting , 2021.
    Association for Research in Otolaryngology
  • Guest Associate Editor
    Research topic: Cochlear Neuron and Ribbon Synapse: Development, Degeneration, Repair and Regeneration
    Frontiers in Neuroscience and Cellular Neurophysiology
  • Panelist, Job Search and Independence, spARO Mentoring Session
    43rd Association for Research in Otolaryngology MidWinter Meeting