Stephen J. Lanspa, MD, MD, MMM
Stephen J. Lanspa, MD, MMM, MD

Stephen J. Lanspa, MD, MMM, MD

Program Director,
School of Medicine

Academic Appointments


  • Medicine


  • Professor

Secondary Appointment

  • Prev. Medicine & Public Health



  • Creighton University School of Medicine,M.D.,to 1978

Publications and Presentations


  • H.T.Lynch, C.L.Snyder, J.F.Lynch, S.Lanspa, P.Silberstein. Molecular Screening, Genetic Counseling, and Cancer Prevention: Lynch Syndrome as a Model. Principles of Molecular Diagnostic and Personalized Cancer Medicine. D.Tan and H.T.Lynch (eds). Lippincott Williams & Wilkens, Not Applicable, 2013


  • Acute Aspirin Use Does Not Increase Urinary Biomarkers of Intestinal Barrier Damage Authors: G. Patrick Lambert, Madeline Novoa, Mary Wulff, Stephen Lanspa, 2017
  • Markers of intestinal damage in individuals with and without obesity.  Leah Hamilton, Geri Moore, Jennifer Yee, Stephen Lanspa, G. Patrick Lambert, International Journal of Exercise Science, submitted, 2017
  • "Phenotypic and Genotypic Heterogeneity of Lynch Syndrome: A Complex Diagnostic Challenge" Lynch HT, Lanspa S, Shaw T, Casey JM, Rendell M, Stacey M, Townley T, Snyder C, Hitchins M, Bailey-Wilson J.
     , Familial Cancer, accepted, 2017
  • Bowel Perforation After Treatment with Sorafenib: A Case Report and Review of Literature. Hamdeh S, Upadhyay S, Khanal N, Lanspa S. J Gastrointest Cancer. 2015 Jul 30. [Epub ahead of print], Journal of Gastrointestinal Cancer, 47(4): 420-2. DOI 10.1007/s12029-015-9752-x, 2016
  • Erin Jenkins-Wessling, Stephen J. Lanspa: Colonoscopy and Chromoscopy in Hereditary Colorectal Cancer Syndromes, Familial Cancer, 15(3), 453-5, 2016
  • Lanspa S, Abdalla AA, Hall BS, Jenkins Wessling E, Kizer R, Mukherjee Reddymasu S: Designing a New Subspecialty Training Fellowship, Alliance for Academic Internal Medicine, 14(2), 15-6, 2016
  • Henry T Lynch MD, Joseph Knezetic PhD & Stephen Lanspa MD: Diagnosing lynch syndrome in absence of colorectal cancer, Expert Opinion on Medical Diagnostics, Expert Opinion on Medical Diagnostics, 6:6, 485-8, 2015
  • SJ Lanspa, HT Lynch: Sessile serrated adenomas: Why conventional endoscopy is OK for unconventional polyps. [Editorial on paper by Pereyra et al., “Finding sessile serrated adenomas: Is it possible to identify them during conventional colonoscopy?” Dig Dis Sci. 2014 Dec;59(12):2848-9, Digestive Diseases and Sciences, 59,12, 2848-9, 2014
  • Henry T. Lynch, Kristen Drescher, Joseph Knezetic, Stephen Lanspa: Genetics, Biomarkers, Hereditary Cancer Syndrome Diagnosis, Heterogeneity and Treatment: A Review. In “Current Treatment Options in Oncology”; David Ettinger, M.D., Editor-in-Chief . Section: Lower Gastrointestinal Cancers; Section Editor: Al B. Benson, MD. 2014, Current Treatment Options in Oncology, 15 (3), 429-42, 2014
  • Matta A, Koppala J, Reddymasu SC, Lanspa S: Acute appendicitis: a potential complication of video capsule endoscopy, BMJ, doi:10.1136/bcr-2014-, 1-3, 2014
  • H.T.LYNCH, K.DRESCHER, P.SHARMA, C.SNYDER, J.F.LYNCH, J.KNEZETIC, M.HITCHINS, P.SILBERSTEIN, S.LANSPA: “Lynch syndrome as model for identification of hereditary high-risk patients”., Not Applicable, In: Cancers of the Colon and Rectum: A Multidisciplinary Approach to Diagnosis and Management edited by A.B.Benson III, A.B.Chakravarthy, S.R.Hamilton, and E.R.Sigurdson., 24-44, 2014
  • Historical Development of Lynch Syndrome Henry T. Lynch, Stephen J. Lanspa, Carrie L. Snyder, Trudy G. Shaw, Patrick M. Lynch: Historical Development of Lynch Syndrome. In ”DNA Alterations in Lynch Syndrome” M. Vogelsang (ed.), DOI 10.1007/978-94-007-6597-9_1, © Springer Science+Business Media Dordrecht 2013, Not Applicable, 2013
  • Lambert,G.P.; Schmidt,A.; Schwarzkopf, K.; Lanspa,S. Effect of aspirin dose on gastrointestinal permeability., International Journal of Sports Medicine, 33, 421–425, 2012
  • De Nazareth, A, M.M. Alla, S.J. Lanspa. Massive Gastric Distension from Chronic Intestinal Pseudo-Obstruction, Western Journal of Emergency Medicine, 13(1), 106–107, 2012
  • Lynch,H.T., K.Drescher, P. Sharma, C. Snyder, J.F.Lynch, J. Knezetic, M. Hitchins, P. Silberstein, S. Lanspa. Multidisciplinary approach to prevention and screening of colorectal cancer: Lynch syndrome as a model for identification of hereditary high-risk patients. Current Multidisciplinary Oncology. A.B.Benson,A.B.Chakravarthy,S.Hamilton,E.Sigurdson(eds.), Demos Medical Publishing, New York., Not Applicable, 2012
  • Lynch HT, Lanspa SJ, Boland CR: Surveillance and management options for Lynch syndrome, US Gastroenterology and Hepatology, in press, 2012
  • G. Patrick Lambert, James Lang, Rebecca Welch, Stephen Lanspa. The Effect of L-Arginine on Absorption of a Glucose-Electrolyte Solution in Humans., Journal of Exercise Physiology online, 14(4), 2011
  • G. Patrick Lambert, James A. Lang, Rebecca Welch, and Stephen J. Lanspa. Effect of L-arginine on absorption of a glucose-electrolyte solution in humans, American Journal of Physiology, submitted, 2011
  • Andrew G De Nazareth, Venkata M Alla, Stephen J Lanspa: Massive gastric distension from chronic intestinal pseudo-obstruction: Mega-stomach!, Western Journal of Emergency Medicine, accepted, 2011
  • Lynch HT, Lanspa SJ, Boland CR: Surveillance and management options for Lynch syndrome, US Gastroenterology and Hepatology, accepted, 2011
  • Lynch HT, Lanspa, Stephen J.; Lynch, Jane F.; Gatalica, Zoran; Jason M Foster: ”FAP, gastric cancer, and genetic counseling featuring children and young adults: a family study and review, Familial Cancer, 9 (4), 581-8, 2010
  • Lynch, H.T., J.F. Lynch, S.J. Lanspa, Familial Pancreatic Cancer, Cancers, 2, 1861-83, 2010
  • Henry T. Lynch,M.D.; Carrie L. Snyder,M.S.N.,R.N.; Janine M. Davies,M.D.; Stephen Lanspa,M.D.; Jane F. Lynch, B.S.N.; Zoran Gatalica,M.D.; Jason M. Foster,M.D: FAP, Gastric Cancer, and Genetic Counseling Featuring Children and Young Adults: A Family Study and Review, Am J Gastroenterol, submitted, 2009
  • Lynch HT, Lynch PM, Lanspa SJ, Snyder CL, Lynch JF, Boland CR. Review of the Lynch syndrome: history, molecular genetics, screening, differential diagnosis, and medicolegal ramifications., Clinical Genetics, 76, 1-18, 2009
  • Cannabinoid Hyperemesis Syndrome: Clinical Diagnosis of an Underrecognised Manifestation of Chronic Cannabis Abuse. Siva Sontineni, MD Sanjay Chaudhary, MD Stephen Lanspa MD Creighton University Medical Center, Omaha, NE., World Journal of Gastroenterology, 15(10), 1264-6, 2009
  • ”Fluid tolerance while running: effect of repeated trials”. Lambert, G. Patrick; Lang, James; Bull, Anthony; Eckerson, Joan; Lanspa, Stephen; O'Brien, John, International Journal of Sports Medicine, 29(11), 878-82, 2008
  • Lynch HT, Lanspa SJ: Commentary on Lynch Syndrome and Related Familial Colorectal Cancers., Critical Reviews in Oncogenesis, 14 (1), 45-53, 2008
  • "Fluid restriction during running increases GI permeability" Lambert GP, LangJ, Bull A, Pfeifer PC, Eckerson J, Moore G, Lanspa SJ., International Journal of Sports Medicine, 29(3), 194-8, 2008
  • Lambert GP, Boylan MW, Laventure JP, Bull AJ, Lanspa SJ: Effect of aspirin and ibuprofen on GI permeability during exercise., International Journal of Sports Medicine, 28(9), 722-6, 2007
  • V. Puri MD, R.W. Lee MD, B.A. Amirlak MD, S.J. Lanspa MD, R. J. Fitzgibbons: Bouveret's syndrome and gallstone ileus., Surgical Laparoscopy, Endoscopy & Percutaneous Techniques, 17(4), 328-30, 2007
  • Fluid Restriction during Running Increases GI Permeability Authors G. P. Lambert1, J. Lang1, A. Bull1, P. C. Pfeifer1, J. Eckerson1, G. Moore1, S. Lanspa2, J. O’Brien2, International Journal of Sports Medicine, 29, Physiology &Biochemistry, 194-198, 2007
  • Effect of Aspirin and Ibuprofen on GI Permeability during Exercise Authors G. P. Lambert1, M. Boylan2, J.-P. Laventure1, A. Bull1, S. Lanspa3, International Journal of Sports Medicine, 28, Physiology&Biochemistry, 722-26, 2007
  • Fructose increases water absorption from a moderately hypertonic glucose-electrolyte solution. G. Patrick Lambert1, Stephen J. Lanspa2, Rebecca Welch3, and Xiaocai Shi4, Journal of Applied Physiology, submitted, 2007
  • Fluid Restriction Increases Gastrointestinal Permeability During Running. G.P. Lambert, J.A. Lang, A.J. Bull, P.C. Pfeifer, J.M. Eckerson, G.A. Moore, J.J. O’Brien, and S.J. Lanspa, International Journal of Sports Medicine, In press, 2007
  • Intestinal Absorption of Hypertonic Solutions Containing Glucose or Glucose and Fructose. G.P.Lambert, S.J.Lanspa, R.Welch, and X.Shi, International Journal of Sport Nutrition & Exercise Metabolism, submitted, 2006
  • Effect of Aspirin or Ibuprofen Ingestion on Gastrointestinal Permeability during Prolonged Exercise G. Patrick Lambert1, Matthew J. Boylan2, Jon-Paul Laventure1, Anthony J. Bull1, and Stephen J. Lanspa3, Med Sci Sports Exer, submitted, 2006
  • Management and Treatment of Crohn's Disease. DeSimone EM, Lanspa SJ, Hogrefe D, Terlaje C., U.S. Pharmacist, 29:05, 95-104, 2004
  • Lanspa, Stephen J. Review of ”Leading Change in Health and Social Care., Not Applicable, Doody's Electronic Journal, accessed December 2003,, 2003
  • Review of “Mergers of Teaching Hospitals in Boston, New York, and Northern California”. Doody’s Review Service (on-line). Available: (Accessed December 2001)., Doody Publishing Inc., 2001
  • Review of “Futurescan 2001”. Doody’s Review Service (on-line). Available: (Accessed December 2001)., Doody Publishing Inc., 2001
  • "Mouth to pouchtransit after restorative proctocolectomy: hydrogen breath analysis correlates with scintigraphy.  Ternet CA, Thorson AG, Blatchford GJ, Christensen MA, Thompson JS, Lanspa SJ, Adrian TE., Am J Gastroenterol, 96(5), 1460-3, 2001
  • Lanspa SJ. Review of ”Extraordinary Board Leadership: the Seven Keys to High-Impact Governance”, Doody Publishing Inc., http://www., 2001
  • Review of ”Finance in Brief: Six Concepts for Healthcare Leaders”; Health Administration Press, 2000, Doody Publishing Inc., http://www., 2000
  • HNPCC: Genetics... in ”Family Cancer and Prevention. 1999, Wiley-Liss., Not Applicable, 1999
  • DIAGNOSTIC INCONSISTENCIES IN BARRETTS-ESOPHAGUS.  SL KIM, JP WARING, SJ SPECHLER, RE SAMPLINER, D SKINNER, and the Department of Veteran Affairs Gastroesophageal Reflux Group, Gastroenterology, 107 (4), 945-9, 1994


  • Hemant Roy, Prabhakar Pradhan, Stephen Lanspa: Identification of Inherited Predisposition to Colonic Neoplasia through Partial Wave Spectroscopic Analysis of the Microscopically Normal Colonic Epithelium, Gastroenterology, May 2008, 2008
  • Sustained virologic response (SVR) to interferon-alfa-2B+/- ribavirin therapy at 6 months reliably predicts long-term clearance of HCV at 5-year follow up., Hepatology, May, 2006, 2006
  • Five-year long term follow up of sustained virologic responders to interferon-alfa-2b+/- ribavirin therapy., Hepatology, May, 2006, 2006
  • GP Lambert, JP Laventure, M Boylan, A Bull, S Lanspa: Gastric comfort and gastric emptying rate are not altered by repeated fluid ingestion during physical training., J Exp Med, 2005
  • M Boylan, JP Laventure, A Bull, S Lanspa, GP Lambert: Comparison of the effects of aspirin and ibuprofen on gastrointestinal(GI) permeability during prolonged exercise., J Exp Med, 2005

Editing and Reviews

  • Henry T. Lynch, Stephen J. Lanspa, Carrie L. Snyder, Kristen M. Drescher: Editorial Comment Microsatellite instability, disease-free survival and role of tumour infiltrating lymphocytes (Invited editorial on ‘Predictors of disease-free survival in colorectal cancer with microsatellite instability: An AGEO multicenter study’), European Journal of Cancer, 51, 922-4, 2015
  • H.T.Lynch, S.Lanspa, J.Knezetic.Diagnosing Lynch Syndrome in Absence of Colorectal Cancer, Expert Opinion on Medical Diagnostics, 6(6), 485-8, 2012
  • Lanspa S.J., Ahnen D., Lynch H.T.: Serrated polyposis - The last (or only the latest?) frontier of familial polyposis?, Am J Gastroenterol, 107, 779-781, 2012
  • Lynch H.T., Lanspa S.J.: Colorectal Cancer Survival Advantage in MUTYH-associated Polyposis and Lynch Syndrome Families, Journal of the National Cancer Institute, 102 (22), 1687-9, 2010
  • Lynch H.T., Jascur T., Lanspa S., Boland C.R.: Making Sense of Missense in the Lynch Syndrome: The Clinical Perspective, Cancer Prev Res, 3(11), 1371-4, 2010
  • S. J. Lanspa, H. T. Lynch: Quality Indicators for Colonoscopy and the Risk of Interval Cancer., New England Journal of Medicine, 363; 14, 1371, 2010


  • 2017 Reflux & Esophageal Update for Primary Care Health Professionals, Chaired session on "Reflux Disease", 2017
  • GI Grand Rounds: "Molecular Genetics of Colon Cancer", 2017
  • "Colon Cancer Screening - Past, Present & Future"; at Practical Gastroenterology: an Update for Primary Care in 2017.  Omaha., 2017
  • GI Grand Rounds: Gallstones and Gallbladder Disease, 2017
  • “Colon Cancer and Hereditary Colon Cancer”
    GI Grand Rounds, 2017
  • Medicine Grand Rounds: "Lessons From an Academic History of Lynch Syndrome"., 2016
  • GI Grand Rounds: "PUD/Gastritis/Functional Dyspepsia", 2016
  • "Colon Cancer Screening - the Basics"; at Practical Gastroenterology: an Update for Primary Care in 2016.  Omaha, 2016
  • “Colonoscopy and Chromoscopy in Hereditary Colorectal Cancer Syndromes” at the “Dr. Henry T. Lynch Symposium on Advances in Hereditary Cancer”. Omaha, Sept 2015, 2015
  • CHI Research update, 2015
  • Population-based healthcare, 2014
  • Hereditary Colon Cancer, ACP Nebraska, Omaha Hilton, 2013
  • G.P. Lambert, A.K. Schmidt, K.A. Schwarzkopf, S.J. Lanspa. Effect of acute aspirin dose and the menstrual cycle on gastrointestinal permeability. Faculty Club Poster., 2012
  • Lambert, G.P., N Bedard, G. Holte, A. Schmidt, S. Lanspa. Lactobacillus acidophilus supplementation for 7 days does not reduce acute aspirin-induced gastrointestinal permeability FASEB J. 23:LB128, 2009. Presented at 2009 Experimental Biology Meeting., 2010
  • The Utility of Tagged Red Blood Cell Imaging in the Era of CT Angiography Tiegs-Heiden CA., Gogia Namrita, Lanspa. SJ, 2010
  • Bad Combination of Polycythemia Vera and Oral Contraceptive Pills – Clots, Clots and Clots! Murukesan, Vidhya., LANSPA, S Poster presented at ACP regional meeting, Omaha, NE, 2010
  • Effect of acute aspirin dose on gastrointestinal permeability. Angela K. Schmidt, Stephen J. Lanspa, and G. Patrick Lambert. St. Albert's Research Day at Creighton University, 2010
  • ACP, Nebraska Chapter. Shivani Aggarwal, MBBS; Erik Stites, BS; Attila Csordas, MD; Stephen Lanspa, MD: Downhill Esophageal Varices: A Complication of Long Term Central Venous Access, 2009
  • ACP, Nebraska Chapter. Veena Kumaravel M.B.B.S, Anna Cook M.D, Stephan J Lanspa M.D.: Is exploratory laparotomy appropriate?, 2009
  • ACP, Nebraska Chapter. Carrie Caruthers, Manu Kaushik MD, Stephen Lanspa, MD, FACG: An Unusual Resolution of Cholecystitis, 2009
  • Effect of the Menstrual Cycle on Permeability of the Gastrointestinal Barrier Kristin A. Schwarzkopf1, Stephen J. Lanspa2, G. Patrick Lambert1. Departments of Exercise Science1 and Medicine2, Creighton University, Omaha, NE. Student Honors Day., 2009
  • Lactobacillus acidophilus supplementation for 7 days does not reduce acute aspirin-induced gastrointestinal permeability G.P. Lambert1, N.A. Bedard1, G.A Holte1, A.K. Schmidt1, S.J. Lanspa2. Departments of 1Exercise Science and 2Medicine, Creighton University, Omaha, NE. At Experimental Biology Annual Meeting, New Orleans., 2009
  • State of the Art- Preventive management of HNPCC vs. Prophylactic Surgery S.J. Lanspa, H.T. Lynch, R.J. Fitzgibbons, Jr. 18th World Congress of the International Association of Surgeons, Gastroenterologists and Oncologists Istanbul, 2008
  • Molecular Basis of Progression in Colorectal Cancer S.J. Lanspa, H.T. Lynch, J.M. Hagenkord 18th World Congress of the International Association of Surgeons, Gastroenterologists and Oncologists Istanbul, 2008
  • Pathogenesis of Hereditary Colorectal Cancer (FAP, AFAP, HNPCC) S.J. Lanspa, H.T. Lynch, Z. Gatalica 18th World Congress of the International Association of Surgeons, Gastroenterologists and Oncologists, Istanbul, 2008
  • “The Role of Medical Organizations”. Grand Rounds, Dept of Psychiatry, University of Nebraska Medical Center, 2007
  • 64. Chaudhary S., Sontineni S., Kaushik M., Gorthi J, Lanspa S: Chronic cannabis abuse and vomiting syndrome with compulsive hot baths. Nebraska ACP, October 2007., 2007
  • Commitment to Professionalism in Medicine. Junior Colloquium., 2007
  • Organizational Medicine, noon conference, 2007
  • GI Critical Care _ Critical Care Conference, 2006
  • Physician Leadership and theJoint Commission - Dept Of Med Managed Care Series, 2006
  • Internal Medicine Board Review Course, 2005
  • Profesionalism Challenges- Dept of Medicine Grand Rounds., 2005
  • Inflammatory Bowel Disease - Family Medicine Conference, 2004
  • Dealing with Ethics and Medical Hierarchy., 2004
  • Professionalism Challenges Conference; Creighton University Department of Medicine Grand Rounds, 2004
  • Moderator for “Colloquium on Colon Cancer”. Fourth Annual: Practical Gastroenterology for Primary Care Physicians. Omaha Marriott, 2001
  • "Nutritional Requirements in the Elderly". Third Annual Practical Gastroenterology for Primary Care Physicians. Omaha Country Club, 2000
  • Update in GI; Okoboji, Ia, 1999
  • Diet and CRC; Iowa Dietetic Assn, 1999
  • Barrett's, 1999
  • Hospitalists, 1999

Research and Scholarship

Grant Funding Received

  • Effect of body composition on intestinal permeability
  • Effect of Ibuprofen Dose on Gastrointestinal Permeability

Awards and Honors

  • America's Top Doctors, Castle Connolly, 2017
  • Leading Physicians of the World 2016, International Association of HealthCare Professionals, 2016
  • Top Doctors, Omaha Magazine, 2014
  • Best Doctors, 2014
  • Best Doctors, 2014
  • America's Top Physicians, 2013
  • America's Top Gastroenterologists 2012(Consumers' Research Council of America), 2013
  • Best Doctors, 2013
  • AGA Academy of Educators, 2012
  • America's Top Gastroenterologists; Consumers' Research Council of America, 2011
  • America's Top Gastroenterologists, 2010, 2011
  • Best Doctors in America, 2011-12, 2011
  • Best Doctors in America, 2009
  • Consumers’ Research Council of America Guide to America’s Top Physicians, 2008
  • Best of the U.S. 2007, Gastroenterology, 2007
  • Selection to ”Best of the U.S.” professionals list, Gastroenterologists, 2006
  • Master Clinician Award, Creighton University School of Medicine, 2006
  • Consumers’ Research Council of America Guide to America’s Top Physicians, 2006
  • Consumers’ Research Council of America Guide to America’s Top Physicians, 2006
  • Best Doctors in America, 2005-2006, 2006