Henry T. Lynch, MD
Henry T. Lynch, MD

Henry T. Lynch, MD

Professor
School of Medicine

Academic Appointments

Department

  • Medicine

Position

  • Professor

Education

  • University of Oklahoma,B.S.,to 1951
  • University of Denver,M.A.,to 1952
  • University of Texas,M.D.,to 1960

Publications and Presentations

Books

  • Chai X, Friebel TM, Singer CF, Evans DG, Lynch HT, Isaacs C, Garber JE, Neuhasuen SL, Matloff E, Eeles, R, Tung N, Weitzel JN, Couch FJ, Hulick PJ, Ganz PA, Daly MB, Olopade OI, Tomlison G, Blum JL, Domchek SM, Chen J, Rebbeck TR. Use of risk-reducing surgeries in a prospective cohort of 1,499 BRCA1 and BRCA2 mutation carriers., Breast Cancer Research and Treatment, 146, 397-406, 2014
  • Juhasz A, Mittal SK, Lee TH, Caishu D, Chak A, Lynch HT. Prevalence of Barrett Esophagus in First-Degree Relatives of Patients With Esophageal Adenocarcinoma., J Clinical Gastro, In Press, 2011
  • Lynch HT, Gatalica Z, Knezetic J. Molecular Genetics and Hereditary Colorectal Cancer: Resolution of the Diagnostic Dilemma of Hereditary Nonpolyposis Colorectal Cancer, Lynch Syndrome, Familial Colorectal Cancer Type X, and Multiple Polyposis Syndromes. Am Soc Clin Oncol Ed Book; The Nuts and Bolts of Molecular Biology For Colorectal Cancer, Not Applicable, 2009
  • Mammary gland architecture as a determining factor in the susceptibility of the human breast to cancer. J Russo, HT Lynch, I Russo., The Breast Journal, 7, 278-291, 2001

Articles

  • Snyder C, Metcalfe K, Sopik V, Royer R, Zhang S, Narod SA, Akbari MR, Lynch HT. Prevalence of PALB2 mutations in the Creighton University Breast Cancer Family Registry., Breast Cancer Research and Treatment, 150, 637-41, 2015
  • Santa Cruz Guidalini R, Win AK, Gulden C, Lindor NM, Newcomb PA, Haile RW, Raymond V, Stoffel E, Hall M, Llor X, Ukaegbu CI, Solomon I, Weitzel J, Kalady M, Blanco A, Terdiman J, Shuttlesworth GA, Lynch PM, Hampel H, Lynch HT, Jenkins MA, Olopade OI, Kupfer SS. Mutation spectrum and risk of colorectal cancer in African American families with Lynch syndrome., Gastroenterology, 2015
  • Kuchenbaecker KB, Ramus SJ, Tyrer J, Lee A, Shen HC, Beesley J, Lawrenson K, McGuffog L, Healey S, Lee JM, Spindler TJ, Lin YG, Pejovic T, Bean Y, Li Q, Coetzee S, Hazelett D, Miron A, Southey M, Terry MB, Goldgar DE, Buys SS, Janavicious R, Dorfling CM, van Rensburg EJ, Neuhausen SL, Ding YC, Hansen TV, Jonson L, Gerdes AM, Ejlertsen B, Barrowdale D, Dennis J, Benitez J, Osorio A, Garcia MJ, Komenaka I, Weitzel JN, Ganschow P, Peterlong P, Bernard L, Viel A, Bonanni B, Peissel B, Manoukian S, Radice P, Papi L, Ottini L, Fostira F, Konstantopoulou I, Garber J, Frost D, Perkins J, Platte R, Ellis S; EMBRACE, Godwin AK, Schmutzler RK, Meindl A, Engel C, Sutter C, Sinilnikova OM; GEMO Study Collaborators, Damiola F, Mazoyer S, Stoppa-Lyonnet D, Claes K, De Leeneer K, Kirk J, Rodriguez GC, Piedmonte M, O’Malley DM, de la Hoya M, Caldes T, Aittomaki K, Nevanlinna H, Collee JM, Rookus MA, Oosterwijk JC; Breast Cancer Family Registry, Tihomirova L, Tung N, Hamann U, Isaccs C, Tischkowitz M, Imyanitov EN, Caligo MA, Campbell IG, Hogervorst FB; HEBON, Olah E, Diez O, Blanco I, Brunet J, Lazaro C, Pujana MA, Jakubowska A, Gronwald J, Lubinski J, Sukiennicki G, Barkardottir RB, Plante M, Simard J, Soucy P, Montagna M, Tognazzo S, Teixeira MR; KConFab Investigators, Pankratz VS, Wang X, Lindor N, Szabo CI, Kauff N, Vijai J, Aghanjanian CA, Pfeiler G, Berger A, Singer CF, Tea MK, Phelan CM, Greene MH, Mai PL, Rennert G, Mulligan AM, Tchatchou S, Andrulis IL, Glendon G, Toland AE, Jensen UB, Kruse TA, Thomassen M, Bojesen A, Zidan J, Friedman E, Laitman Y, Soller M, Liljegren A, Arver B, Einbeigi Z, Stenmark-Askmalm M, Olopade OI, Nussbaum RL, Rebbeck TR, Nathanson KL, Domchek SM, Lu KH, Karlan BY, Walsh C, Lester J; Australian Cancer Study (Ovarian Cancer Investigators); Australian Ovarian Cancer Study Group, Hein A, Ekici AB, Beckmann MW, Fasching PA, Lambrechts D, Van Nieuwenhuysen E, Vergote I, Lambrechts S, Dicks E, Doherty JA, Wicklund KG, Rossing MA, Rudolph A, Chang-Claude J, Wang-Gohrke S, Eilber U, Moysich KB, Odunsi K, Sucheston L, Lele S, Wilkens LR, Goodman MT, Thompson PJ, Shvetsov YB, Runnebaum IB, Durst M, Hillemanns P, Dork T, Antonenkova N, Bogdanova N, Leminen A, Pelttari LM, Butzow R, Modugno F, Kelley JL, Edwards RP, Ness RB, du Bois A, Heitz F, Schwaab I, Harter P, Matsuo K, Hosono S, Orsulic S, Jensen A, Kjaer SK, Hogdall E, Hasmad HN, Azmi MA, Teo SH, Woo YL, Fridley BL, Goode EL, Cunningham JM, Vierkant RA, Bruinsma F, Giles GG, Lian D, Hildebrandt MA, Wu X, Levine DA, Bisogna M, Bercheck A, Iversen ES, Schildkraut JM, Concannon P, Weber RP, Cramer DW, Terry KL, Poole EM, Tworoger SS, Bandera EV, Orlow I, Olson SH, Krakstad C, Salvensen HB, Tangen IL, Bjorge L, van Altena AM, Aben KK, Kiemeney LA, Massuger LF, Kellar M, Brooks-Wilson A, Kelemen LE, Cook LS, Le ND, Cyulski C, Yang H, Lissowska J, Brinton LA, Wentzensen N, Hogdall C, Lundvall L, Nedergaard L, Baker H, Song H, Eccles D, McNeish I, Paul J, Carty K, Siddiqui N, Glasspool R, Whittemore AS, Rothstein JH, McGuire V, Sieh W, Ji BT, Zheng W, Shu XO, Gao YT, Rosen B, Risch HA, McLaughlin JR, Narod SA, Monteiro AN, Chen A, Lin HY, Permuth-Wey J, Sellers TA, Tsai YY, Chen Z, Ziogas A, Anton-Culver H, Gentry-Maharaj A, Menon U, Harrington P, Lee AW, Wu AH, Pearce CL, Coetzee G, Pike MC, Dansonka-Mieszkowska A, Timorek A, Rzepecka IK, Kupryjanczyk J, Freedman M, Noushmehr H, Easton DF, Offit K, Couch FJ, Gayther S, Pharoah PP, Antoniou AC, Chenevix-Trench G; Consortium of Investigators of Modifiers of BRCA1 and BRCA2 [Lynch HT]. Identification of six new susceptibility loci for invasive epithelial ovarian cancer., Nature Genetics, 47, 164-71, 2015
  • Blanco I, Kuchenbaecker K, Cuadras D, Wang X, Barrowdale D, de Garibay GR, Librado P, Sanchez-Garcia A, Rozas J, Bonifaci N, McGuffog L, Pankratz VS, Islam A, Mateo F, Berenguer A, Petit A, Catala I, Brunet J., Feliubadalo L, Tornero E, Benitez J, Osorio A, Ramon y Cajal T, Nevanlinna H, Aittomaki K, Arun BK, Toland AE, Karlan BY, Walsh C, Lester J, Greene MH, Mai PL, Nussbaum RL, Andrulis IL, Domchek SM, Nathanson KL, Rebbeck TR, Barkardottir RB, Jakubowska A, Lubinski J, Durda K, Jaworskak-Bieniek K, Claes K, Van Maerken T, Diez O, Hansen TV, Jonso L, Gerdes AM, Ejlertsen B, de la Hoya M, Caldes T, Dunning AM, Oliver C, Fineberg E, Cook M, Peock S, McCanne E, Murray A, Jacobs C, Pichert G, Lalloo F, Chu C, Dorkins H, Paterson J, Ong KR, Teixera MR; Teixeira, Hogervorst FB, van der Hout AH, Seynaeve C, van der Luijt RB, Ligtenberg MJ, Devilee P, Wijnen JT, Rookus MA, Meijers-Heijboer HE, Blok MJ, van den Ouweland AM, Aalfs CM, Rodriguez GC, Phillips KA, Piedmonte M, Nerenstone SR, Bae-Jump VL, O’Malley DM, Ratner ES, Schmutzler RK, Wappenschmidt B, Rhiem K, Engel C, Meindl A, Ditsch N, Arnold N, Plendl HJ, Niederacher D, Sutter C, Wang-Gohrke S, Steinemann D, Preisler-Adams S, Kast K, Varon-Mateeva R, Gehrig A, Bojesen A, Pedersen IS, Sunde L, Jensen UB, Thomassen M, Kruse TA, Foretova L, Peterlongo P, Bernard L, Peissel B, Scuvera G, Manoukian S, Radice P, Ottini L, Montagna M, Agata , Maugard C, Simard J, Soucy P, Berger A, Fink-Retter A, Singer CF, Rappaport C, Geschwantler-Kaulich D, Tea MK, Pfeiler G; BCFR, John EM, Miron A, Neuhausen SL, Terry MB, Chung WK, Daly MB, Goldgar DE, Janavicius R, Dorfling CM, van Rensburg EJ, Fostira F, Konstantopoulou I, Garber J, Godwin AK, Olah E, Narod SA, Rennert G, Paluch SS, Laitman Y, Friedman E; SWE-BRCA, Liljegren A, Rantala J, Stenmark-Askmalm M, Loman N, Imyanitov EN, Hamann U; kConFab Investigators, Spurdle AB, Healey S, Weitzel JN, Herzog J, Margileth D, Gorrini C, Esteller M, Gomez A, Sayols S, Vidal E, Heyn H; GEMO, Stoppa-Lyonnet D, Leone M, Barjhoux L, Fassy-Colcombet M, de Paus W, Lasset C, Ferrer SF, Castera L, Berthet P, Cornelis F, Bignon YJ, Damiola F, Mazoyer S, Sinilnikova OM, Maxwell CA, Vijai J, Robson M, Kauff N, Corines MJ, Villano D, Cunningham J, Lee A, Lindor N, Lazaro C, Easton DF, Offit K, Chenevix-Trench G, Couch FJ, Antoniou AC, Pujana, MA, [Lynch HT]. Assessing associations between the AURKA-HMMR-TPX2-TUBG1 functional module and breast cancer risk in BRCA 1/2 mutation carriers., PLoS One, 105, 637-41, 2015
  • Semple J, Metcalfe KA, Lubinski J, Huzarski T, Gronwald J, Armel S, Lynch HT, Karlan B, Foulkes W, Singer CF, Neuhasuen SL, Eng C, Iqbal J, Narod SA; Hereditary Breast Cancer Clinical Study Group. Does the age of breast cancer diagnosis in first-degree relatives impact on the risk of breast cancer in BRCA1 and BRCA2 mutation carriers?, Womens Health (Lond Engl), 11, 453-9, 2015
  • Tiwari AK, Roy HK, Lynch HT. Lynch syndrome in the 21st century: clinical perspectives., QJM, 2015
  • Metcalfe K, Lynch HT, Foulkes WD, Tung N, Kim-Sing C, Olopade OI, Eisen A, Rosen B, Snyder C, Gershman S, Sun P, Narod SA. Effect of oophorectomy on survival after breast cancer in BRCA1 and BRCA2 mutation carriers., JAMA, 1, 306-13, 2015
  • Kotsopoulos J, Lubinski J, Neuhausen SL, Gronwald J, Lynch HT, Huzarski T, Demsky R, Foulkes WD, Senter L, Friedman S, Ainsworth, P, Sun P, Narod SA. Weight gain after oophorectomy among women with a BRCA1 or BRCA2 mutation., Womens Health (Lond Engl), 11, 453-9, 2015
  • Snyder CL, Casey MJ, Lynch HT. Should risk-reducing surgery in women from hereditary breast ovarian cancer families be confined to removal of the fallopian tubes with ovarian conservation?, Womens Health (Lond Engl), 11, 423-7, 2015
  • Cybulski C, Lubinski J, Huzarski T, Lynch HT, Randall SA, Neuhausen SL, Senter L, Friedman S, Ainsowrth P, Singer, C, Foulkes WD, Narod SA, Sun P, Kotsopoulos J. Prospective evaluation of alcohol consumption and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers., Breast Cancer Research and Treatment, 151(2), 435-41, 2015
  • Downs B, Kim YC, Xiao F, Snyder C, Chen P, Fleissner EA, Becirovic D, Wen H, Sherman S, Cowan KH, Lynch HT, Wang SM. Two PALB2 germline mutations found in both BRAC1+ and BRCAx familial breast cancer., Breast Cancer Research and Treatment, 151(1), 219-24, 2015
  • Casey MJ, Bewtra C, Lynch HT, Snyder CL, Stacey M. Endometrial cancers in mutation carriers from hereditary breast ovarian cancer syndrome kindreds: report from the Creighton University Hereditary Cancer Registry with review of the implications., International Journal Gynecol Cancer, 25(4), 650-6, 2015
  • Goodenberger ML, Thomas BC, Riegert-Johnson D, Boland CR, Plon SE, Clendenning M, Win AK, Senter L, Lipkin SM, Stadler ZK, Macrae FA, Lynch HT, Weitzel JN, de la Chapelle A, Syngal S, Lynch P, Parry S, Jenkins MA, Gallinger S, Holter S, Aronson M, Newcomb PA, Burnett T, Le Marchand L, Pichurin P, Hampel H, Terdiman JP, Lu KH, Thibodeau S, Lindor NM. PMS2 monoallelic mutation carriers: the known unknown., Genet Med, Epub ahead of print, 2015
  • Segev Y, Rosen B, Lubinski J, Gronwald J, Lynch HT, Moller P, Kim-Sing C, Ghadirian P, Karlan B, Eng C, Gilchrist D, Neuhausen SL, Eisen A, Friedman E, Euhus D, Ping S, Narod SA; Hereditary Breast Cancer Study Group. Risk factors for endometrial cancer among women with a BRCA1 or BRCA2 mutation: a case control study., Familial Cancer, Epub ahead of print, 2015
  • Eskander,RN, Lynch,HT, Brown,SM, Wagman,LD, Tewai,KS. Novel MSH2 Mutation in the First Report of a Vietnamese-American Kindred with Lynch Syndrome., Gynecologic Oncology, 12, 31-3, 2015
  • Lynch HT, Snyder CL, Shaw TG, Heinen CD, Hitchins MP. Milestones of Lynch syndrome: 1895-2015., Nature Reviews, 15, 181-194, 2015
  • Lynch H, Snyder C, Wang SM. Considerations for comprehensive assessment of genetic predisposition to familial breast cancer., The Breast Journal, 21, 67-75, 2015
  • Bikhchandani J, Lynch HT. Commentary on 'Colonoscopy screening compliance and outcomes in patients with Lynch syndrome'., Colorectal Disease, 17(1), 46-9, 2015
  • Schlussel AT, Gagliano RA Jr, Seto-Donlon S, Eggerding F, Donlon T, Berenberg J, Lynch HT. The evolution of colorectal cancer genetics – Part 1: from discovery to practice., J Gastrointest Oncol, 5, 326-335, 2014
  • Schlussel AT, Gagliano RA Jr, Seto-Donlon S, Eggerding F, Donlon T, Berenberg J, Lynch HT. The evolution of colorectal cancer genetics – Part 2: clinical implications and applications., J Gastrointest Oncol, 5, 336-344, 2014
  • Giannakeas V, Lubinski J, Gronwald J, Moller P, Armel S, Lynch HT, Foulkes WD, Kim-Sing C, Singer C, Neuhausen SL, Friedman E, Tung N, Senter L, Sun P, Narod SA. Mammography screening and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers: a prospective study., Breast Cancer Research and Treatment, 147, 113-118, 2014
  • Wen H, Kim YC, Snyder C, Xiao F, Fleissner EA, Becirovic D, Luo J, Downs B, Sherman S, Cowan KH, Lynch HT, Wang SM. Family-specific, novel, deleterious germline variants provide a rich resource to identify genetic predispositions for BRCAx familial breast cancer., BMC Cancer, 14, 470, 2014
  • Lynch HT, Snyder C, Stacey M, Olson B, Peterson SK, Buxbaum S, Shaw T, Lynch P. Communication and technology in genetic counseling for hereditary cancer., Clinical Genetics, 85, 213-222, 2014
  • Gatalica Z, Snyder C, Maney T, Ghazalpour A, Holterman DA, Xiao N, Overberg P, Rose I, Basu GD, Vranic S, Lynch HT, Von Hoff DD, Hamid O. Programmed Cell Death 1 (PD-1) and its Ligand (PD-L1) in Common Cancers and Their Correlation with Molecular Cancer Type., Cancer Epidemiol Biomarkers Prev, 23, 2965-2970, 2014
  • Park DJ, Tao K, Calvez-Kelm FL, Nguyen-Dumont T, Robinot N, Hammet F, Odefrey F, Tsimiklis H, Teo ZL, Thingholm LB, Young EL, Voegele C, Lonie A, Pope BJ, Roane TC, Bell R, Hu H, Shankaracharya, Huff CD, Ellis J, Li J, Makunin IV, John EM, Andrulis IL, Terry MB, Daly M, Buys SS, Snyder C, Lynch HT, Devilee P, Giles GG, Hopper JL, Feng B-J, Lesueur F, Tavtigian SV, Southey MC, Goldgar DE. Rare Mutations in RINT1 Predispose Carriers to Breast and Lynch Syndrome-Spectrum Cancers., Cancer Discovery, 4, 804-815, 2014
  • Gronwald J, Robidoux A, Kim-Sing C, Tung N, Lynch HT, Foulkes WD, Manoukian S, Ainsworth P, Neuhausen SL, Demsky R, Eisen A, Singer CF, Saal H, Senter L, Eng C, Weitzel J, Moller P, Gilchrist DM, Olopade O, Ginsburg O, Sun P, Huzarski T, Lubinski J, Narod SA; The Hereditary Breast Cancer Clinical Study Group. ”Duration of tamoxifen use and the risk of contralateral breast cancer in BRCA1 and BRCA2 mutation carriers.”, Breast Cancer Research and Treatment, EPUB ahead of print, 2014
  • Xiao F, Kim YC, Snyder C, Wen H, Chen PX, Luo J, Becirovic D, Downs B, Cowan KH, Lynch H, Wang SM.”Genome instability in blood cells of a BRCA1+ breast cancer family.”, BMC Cancer, 14(1), 342, 2014
  • Lynch HT, Drescher K, Knezetic J, Lanspa S.”Genetics, Biomarkers, Hereditary Cancer Syndrome Diagnosis, Heterogeneity and Treatment: A Review.”, Current Treatment Options in Oncology, Epub Ahead of Print, 2014
  • Hitchins MP, Lynch HT. Dawning of the epigenetic era in hereditary cancer., Clinical Genetics, Epub ahead of print, 2014
  • Metcalfe K, Gershman S, Ghadirian P, Lynch HT, Snyder C, Tung N, Kim-Sing C, Eisen A, Foulkes WD, Rosen B, Sun P, Narod SA. Contralateral mastectomy and survival after breast cancer in carriers of BRCA1 and BRCA2 mutations: retrospective analysis., BMJ, 11, g266, 2014
  • Kotsopoulos J, Lubinski J, Moller P, Lynch HT, Singer CF, Eng C, Neuhausen SL, Karlan B, Kim-Sing C, Huzarski T, Gronwald J, McCuaig J, Senter L, Tung N, Ghadirian P, Eisen A., Gilchrist D, Blum JL, Zakalik D, Pal T, Sun P, Narod SA; Hereditary Breast Cancer Clinical Study Group. Timing of oral contraceptive use and the risk of breast cancer in BRCA1 mutation carriers., Breast Cancer Research and Treatment, 143(3), 579-86, 2014
  • Finch A, Lubinski J, Moller P, Maehle L, Singer C, Senter L, Rosen B, Karlan B, Ghadirian P, Cybulski C, Eisen A, Foulkes WD, Charmaine K-S, Ainsworth P, Tung N, Lynch HT, Neuhausen S, Metcalfe K, Thompson I, Murphy J, Sun P, Narod SA. Impact of oophorectomy on Cancer Incidence and Mortality in Women who carry a BRCA1 or BRCA2 Mutation., J Clinical Oncology, Epub ahead of print, 2014
  • Lin-Hurtubise KM, Yheulon CG, Gagliano RA Jr, Lynch HT. Excess of extracolonic non-endometrial multiple primary cancers in MSH2 germline mutation carriers over MLH1., J Surg Oncol, 108(7), 433-7, 2013
  • Casey MJ, Bewtra C, Lynch HT, Snyder C, Stacy M, Watson P. Phenotypic heterogeneity of hereditary gynecologic cancers: a report from the Creighton hereditary cancer registry., Familial Cancer, 12(4), 719-40, 2013
  • Valentini A, Finch A, Lubinski J, Byrski T, Ghadirian P, Kim-Sing C, Lynch HT, Ainsworth PJ, Neuhausen SL, Greenblatt E, Singer C, Sun P, Narod SA. Chemotherapy-induced amenorrhea in patients with breast cancer with a BRCA1 or BRCA2 mutation., J Surg Oncol, 31(31), 3914-9, 2013
  • Semple J, Metcalfe KA, Lynch HT, Kim-Sing C, Senter L, Pal T, Ainsworth P, Lubinski J, Tung N, Eng C, Gilchrist D, Blum J, Neuhausen SL, Singer CF, Ghadirian P, Sun P, Narod SA; Hereditary Breast Cancer Clinical Study Group. International rates of breast reconstruction after prophylactic mastectomy in BRCA1 and BRCA2 mutation carriers., Annals of Surgical Oncology, 20(12), 3817-22, 2013
  • Valentini A, Lubinski J, Byrski T, Ghadirian P, Moller P, Lynch HT, Ainsworth P, Neuhausen SL, Weitzel J, Singer CF, Olopade OI, Saal H, Lyonnet DS, Foulkes WD, Kim-Sing C, Manoukian S, Zakalik D, Armel S, Senter L, Eng C, Grunfeld E, Chiarelli AM, Poll A, Sun P, Narod SA; Hereditary Breast Cancer Clinical Study Group.”The impact of pregnancy on breast cancer survival in women who carry a BRCA1 or BRCA2 mutation.”, Breast Cancer Research and Treatment, 142(1), 177-85, 2013
  • Lynch H, Wen H, Kim YC, Snyder C, Kinarsky Y, Chen PX, Xiao F, Goldgar D, Cowan KH, Wang SM. Can unknown predisposition in familial breast cancer be family-specific?, The Breast Journal, 19(5), 520-8, 2013
  • Moul JW, Walsh PC, Rendell MS, Lynch HT, Leslie SW, Kosoko-Laskai O, Fitzgibbons WP, Powell I, D’Amico AV, Catalona WJ. Early detection of prostate cancer: AUA guideline: H.B. Carter, P.C. Albertsen, J.J. Barry, R. Etzioni, S.J. Freedlandk, K.L. Greene, L. Holmberg, P. Kantoff, B.R. Konety, M.H. Murad, D.F. Penson and A.L. Zietman., Journal of Urology, 190(3), 419-246, 2013
  • Lynch HT, Lynch PM. Update on the clinical management of Lynch syndrome., Nature Reviews, 10, 323-324, 2013
  • Lynch HT, Shaw TG. Practical genetics of colorectal cancer., Chin J Oncology, 2, 12, 2013
  • Lu KH, Loose DS, Yates MS, Nogueras-Gonzalez GM, Munsell MF, Chen L, Lynch H, Cornelison T, Boyd-Rogers S, Rubin M, Daniels MS, Conrad P, Milbourne A, Gershenson DM, Broaddus RR. Prospective multicenter randomized intermediate biomarker study of oral contraceptive versus depo-provera for prevention of endometrial cancer in women with Lynch syndrome., Cancer Prev Res, 6(8), 774-81, 2013
  • COMPLEXO, Southey MC, Park DJ, Nguyen-Dumont T, Campbell I, Thompson E, Trainer AH, Chenevix-Trench G, Simard J, Dumont M, Soucy P, Thomassen M, JØnson L, Pedersen IS, Hansen TV, Nevanlinna H, Khan S, Sinilnikova O, Mazoyer S, Lesueur F, Damiola F, Schmutzler R, Meindl A, Hahnen E, Dufault MR, Chris Chan T, Kwong A, Barkardóttir R, Radice P, Peterlongo P, Devilee P, Hilbers F, Benitez J, Kvist A, Törngren T, Easton D, Hunter D, Lindstrom S, Kraft P, Zheng W, Gao YT, Long J, Ramus S, Feng BJ, Weitzel JN, Nathanson K, Offit K, Joseph V, Robson M, Schrader K, Wang SM, Kim YC, Lynch H, Snyder C, Tavtigian S, Neuhausen S, Couch FJ, Goldgar DE. COMPLEXO: identifying the missing heritability of breast cancer via next generation collaboration., Breast Cancer Research, 15(3), 402, 2013
  • Lynch HT, Lynch PM. Foreward for “100 years of Lynch syndrome.”, Familial Cancer, 12(2), 2013
  • Gatalica Z, Chen M, Snyder C, Mittal S, Lynch HT. Barrett’s esophagus in the patients with familial adenomatous polyposis., Familial Cancer, EPub ahead of print, 2013
  • Cossack M, Ghaffary C, Watson P, Snyder C, Lynch H. Aspirin use is associated with lower prostate cancer risk in male carriers of BRCA mutations., J Genet Couns, 2013
  • Segev Y, Iqbal J, Lubinski J, Gronwald J, Lynch HT, Moller P, Ghadirian P, Rosen B, Tung N, Kim-Sing C, Foulkes WD, Neuhausen SL, Senter L, Singer CF, Karlan B, Ping S, Narod SA; Hereditary Breast Cancer Study Group.”The incidence of endometrial cancer in women with BRCA1 and BRCA2 mutations: an international prospective cohort study.”, Gynecologic Oncology, 130(1), 127-31, 2013
  • Segev Y, Iqbal J, Lubinski J, Gronwald J, Lynch HT, Moller P, Ghadirian P, Rosen B, Ping S, Narod SA; Hereditary Breast Cancer Study Group. The incidence of endometrial cancer in women with BRCA1 and BRCA2 mutations: An international prospective cohort study., Gynecologic Oncology, S0090-8258(13), 00182-0, 2013
  • Boland CR, Lynch HT. The History of Lynch Syndrome., Familial Cancer, Epub Ahead of Print, 2013
  • Finch A, Valentini A, Greenblatt E, Lynch HT, Ghadirian P, Armel S, Neuhausen SL, Kim-Sing C, Tung N, Karlan B, Foulkes WD, Sun P, Narod S; Hereditary Breast Cancer Study Group. Frequency of premature memopause in women who carry a BRCA1 or BRCA2 mutation., Fertility & Sterility, Epub ahead of print, 2013
  • Gracia-Arznarez FJ, Fernandez V, Pita G, Peterlongo P, Dominguez O, de la Hoya M, Duran M, Osorio A, Moreno L, Gonzalez-Neira A, Rosa-Rosa JM, Sinilnikova O, Mazoyer S, Hopper J, Lazaro C, Southey M, Odefrey F, Manoukian S, Catucci I, Caldes T, Lynch HT, Hilbers FS, van Asperen CJ, Vasen HF, Goldgar D, Radice P, Devilee P, Benitez J. Whole exome sequencing suggests much of non-BRCA1/BRCA2 familial breast cancer is due to moderate and low penetrance susceptibility alleles., PLoS One, 8(2), e55681, 2013
  • Narod SA, Metcalfe K, Lynch HT, Ghadirian P, Robidoux A, Tung N, Gaughan E, Kim-Sing C, Olopade OI, Foulkes WD, Robson M, Offit K, Jakubowska A, Byrski T, Huzarski T, Sun P, Lubinski J. Should all BRCA1 mutation carriers with stage I breast cancer receive chemotherapy?, Breast Cancer Research and Treatment, 138(1), 273-9, 2013
  • Fan M, Pfeffer SR, Lynch HT, Cassidy P, Leachman S, Pfeffer LM, Kopelovich L. Altered transcriptome signature of phenotypically normal skin fibroblasts heterozygous for CDKN2A in familial melanoma: relevance to early intervention., Oncotarget, 4(1), 128-41, 2013
  • Lynch HT, Shaw TG. Familial prostate cancer and HOXB13 founder mutations: geographic and racial/ethnic variations., Human Genetics, 132(1), 1-4, 2013
  • Anderson MA, Zolotarevsky E, Cooper KL, Sherman S, Shats O, Whitcomb DC, Lynch HT, Ghiorzo P, Rubinstein WS, Vogel KJ, Sasson AR, Grizzle WE, Ketcham MA, Lee SY, Normolle D, Plonka CM, Mertens AN, Tripon RC, Brand RE. Alcohol and tobacco lower the age of presentation in sporadic pancreatic cancer in a dose-dependent manner: a multicenter study., Am J Gastroenterol, 107(11), 1730-9, 2012
  • Brand R, Nielsen M, Lynch H., Infante E. MUTYH-Associated Polyposis. In: Pagon RA, Bird TD, Dolan CR, Stephens K, Adam MP, editors. GeneReviews [Internet]. Seattle (WA): Univeristy of Washington, Seattle, Not Applicable, 2012
  • Lynch HT, Knezetic J, Lanspa S. Diagnosing Lynch syndrome in the absence of colorectal cancer., Expert Opinion on Medical Diagnostics, 6(6), 485-8, 2012
  • Damania D, Roy HK, Subramanian H, Weinberg DS, Rex DK, Goldberg MJ, Muldoon J, Cherkezyan L, Zhu Y, Bianchi LK, Shah D, Pradhan P, Borkar M, Lynch H, Backman V. Nanocytology of rectal colonocytes to assess risk of colon cancer based on field cancerization., Cancer Research, 72(11), 2720-7, 2012
  • Finkelman BS, Rubinstein WS, Friedman S, Friebel TM, Dubitsky S, Schonberger NS, Shoretz R, Singer CF, Blum JL, Tung N, Olopade OI, Weitzel JN, Lynch HT, Snyder C, Garber JE, Schildkraut J, Daly MB, Isaacs C, Pichert G, Neuhausen SL, Couch FJ, Van't Veer L, Eeles R, Bancroft E, Evans DG, Ganz PA, Tomlinson GE, Narod SA, Matloff E, Domcheck S, Rebbeck TR. Breast and Ovarian Cancer Risk and Risk Reduction in Jewish BRCA1/2 Mutation Carriers., J Clinical Oncology, 30(12), 1321-8, 2012
  • Adonizio C, Gazzillo M, Knezetic J, Snyder, C, Lynch HT, Rybak C, Hall MJ, Lowstuter K, Eggington J, Morris GJ. Thirty-Nine-Year-Old With Familial Colon Cancer, and Variant of Undetermined Significance in MSH6., Semin Oncol, 39(2), 2012
  • Couch FJ, Gaudet MM, Antoniou AC, Ramus SJ, Kuchenbaecker KB, Soucy P, Beesley J, Chen X, Wang X, Kirchhoff T, McGuffog L, Barrowdale D, Lee A, Healey S, Sinilnikova OM, Andrulis IL; OCGN, Ozcelik H, Mulligan AM, Thomassen M, Gerdes AM, Jensen UB, Skytte AB, Kruse TA, Caligo MA, von Wachenfeldt A, Barbany-Bustinza G, Loman N, Soller M, Ehrencrona H, Karlsson P; SWE-BRCA, Nathanson KL, Rebbeck TR, Domchek SM, Jakubowska A, Lubinski J, Jaworska K, Durda K, Zlowocka E, Huzarski T, Byrski T, Gronwald J, Cybulski C, Gorski B, Osorio A, Duran M, Tejada MI, Benitez J, Hamann U, Hogervorst FB; HEBON, van Os TA, van Leeuwen FE, Meijers-Heijboer HE, Wijnen J, Blok MJ, Kets M, Hooning MJ, Oldenburg RA, Ausems MG, Peock S, Frost D, Ellis SD, Platte R, Fineberg E, Evans DG, Jacobs C, Eeles RA, Adlard J, Davidson R, Eccles DM, Cole T, Cook J, Paterson J, Brewer C, Douglas F, Hodgson SV, Morrison PJ, Walker L, Porteous ME, Kennedy MJ, Side LE; EMBRACE, Bove B, Godwin AK, Stoppa-Lyonnet D; GEMO Study Collaborators, Fassy-Colcombet M, Castera L, Cornelis F, Mazoyer S, Leone M, Boutry-Kryza N, Bressac-de Paillerets B, Caron O, Pujol P, Coupier I, Delnatte C, Akloul L, Lynch HT, Snyder CL, Buys SS, Daly MB, Terry M, Chung WK, John EM, Miron A, Southey MC, Hopper JL, Goldgar DE, Singer CF, Rappaport C, Tea MK, Fink-Retter A, Hansen TV, Nielsen FC, Arason A, Vijai J, Shah S, Sarrel K, Robson ME, Piedmonte M, Phillips K, Basil J, Rubinstein WS, Boggess J, Wakeley K, Ewart-Toland A, Montagna M, Agata S, Imyanitov EN, Isaacs C, Janavicius R, Lazaro C, Blanco I, Feliubadalo L, Brunet J, Gayther SA, Pharoah PP, Odunsi KO, Karlan BY, Walsh CS, Olah E, Teo SH, Ganz PA, Beattie MS, van Rensburg EJ, Dorfling CM, Diez O, Kwong A, Schmutzler RK, Wappenschmidt B, Engel C, Meindl A, Ditsch N, Arnold N, Heidemann S, Niederacher D, Preisler-Adams S, Gadzicki D, Varon-Mateeva R, Deissler H, Gehrig A, Sutter C, Kast K, Fiebig B, Heinritz W, Caldes T, de la Hoya M, Muranen TA, Nevanlinna H, Tischkowitz MD, Spurdle AB, Neuhausen SL, Ding YC, Lindor NM, Fredericksen Z, Pankratz VS, Peterlongo P, Manoukian S, Peissel B, Zaffaroni D, Barile M, Bernard L, Viel A, Giannini G, Varesco L, Radice P, Greene MH, Mai PL, Easton DF, Chenevix-Trench G; kConFab investigators, Offit K, Simard J; Consortium of Investigators of Modifiers of BRCA1/2. Common Variants at the 19p12.1 and ZNF365 Loci Are Associated with ER Subtypes of Breast Cancer and Ovarian Cancer Risk in BRCA1 and BRCA2 Mutation Carriers., Cancer Epidemiol Biomarkers Prev, 21(4), 645-657, 2012
  • Lynch HT, Snyder C, Lynch J, Hereditary Breast Cancer: Practical Pursuit for Clinical Translation., Annals of Surgical Oncology, Epub ahead of print, 2012
  • Kotsopoulos J, Lubinski J, Salmena L, Lynch HT, Kim-Sing C, Foulkes WD, Ghadirian P, Neuhausen SL, Demsky R, Tung N, Ainsworth P, Senter L, Eisen A, Eng C, Singer C, Ginsburg O, Blum J, Huzarski T, Poll A, Sun P, Narod SA; the Hereditary Breast Cancer Clinical Study Group. Breastfeeding and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers., Breast Cancer Research, 14(2), R42 - Epub ahead of print, 2012
  • McGee J, Kotsopoulos J, Lubinski J, Lynch HT, Rosen B, Tung N, Kim-Sing C, Karlan B, Foulkes WD, Ainsworth P, Ghadirian P, Senter L, Eisen A, Sun P, Narod SA. Anthropometric Measures and Risk of Ovarian Cancer Among BRCA1 and BRCA2 Mutation Carriers., Obesity (Silver Spring), Epub Ahead of Print, 2012
  • Burn J, Gerdes AM, Macrae F, Mecklin JP, Moeslein G, Olschwang S, Eccles D, Evans DG, Maher ER, Bertario L, Bisgaard ML, Dunlop MG, Ho JW, Hodgson SV, Lindblom A, Lubinski J, Morrison PJ, Murday V, Ramesar R, Side L, Scott RJ, Thomas HJ, Vasen HF, Barker G, Crawford G, Elliott F, Movahedi M, Pylvanainen K, Wijnen JT, Fodde R, Lynch HT, Mathers JC, Bishop DT,; CAPP2 Investigators. Long-term effect of aspirin on cancer risk in carriers of hereditary colorectal cancer: an analysis from the CAPP2 randomised controlled trial., Lancet, 378(9809), 2081-7, 2011
  • Weissman SM, Burt R, Church J, Erdman S, Hampel H, Holter S, Jasperson K, Kalady MF, Haidle JL, Lynch HT, Palaniappan S, Wise PE, Senter L. Identification of Individuals at Risk for Lynch Syndrome Using Targeted Evaluations and Genetic Testing: National Society of Genetic Counselors and the Collaborative Group of the Americas on Inherited Colorectal Cancer Joint Practice Guideline., J Genet Couns, Epub Ahead of Print, 2011
  • Lynch HT, Aldoss I, Lynch JF. The identification and management of hereditary diffuse gastric cancer in a large Jordanian family., Familial Cancer, 10(4), 667-72, 2011
  • Lynch HT, Lynch JF, Gatalica Z, Boland CR. Lynch syndrome: its phenotypic and genotypic heterogeneity., Viszeralmedizin, 2, 2011
  • Mulligan AM, Couch FJ, Barrowdale D, Domchek SM, Eccles D, Nevanlinna H, Ramus SJ, Robson M, Sherman M, Spurdle AB, Wappenschmidt B, Lee A, McGuffog L, Healey S, Sinilnikova OM, Janavicius R, Hansen Tv, Nielsen FC, Ejlertsen B, Osorio A, Munoz-Repeto I, Duran M, Godino J, Pertesi M, Benitez J, Peterlongo P, Manoukian S, Peissel B, Zaffaroni D, Cattaneo E, Bonanni B, Viel A, Pasini B, Papi L, Ottini L, Savarese A, Bernard L, Radice P, Hamann U, Verheus M, Meijers-Heijboer HE, Wijnen J, Gomez Garcia EB, Nelen MR, Kets CM, Seynaeve D, Tilanus-Linthorst MM, van der Luijt RB, van Os T, Rookus M, Frost D, Jones JL, Evans DG, Lalloo F, Eeles R, Izatt L, Adlard J, Davidson R, Cook J, Donaldson A, Dorkins H, Gregory H, Eason J, Houghton C, Barwell J, Side LE, McCann E, Murray A, Peock S, Godwin AK, Schmutzler RK, Rhiem K, Engel C, Meindl A, Ruehl I, Arnold N, Niederacher D, Sutter C, Deissler H, Gadzicki D, Kast K, Preisler-Adams S, Varon-Mateeva R, Schoenbuchner I, Fiebig B, Heinritz W, Schafer D, Gevensleben H, Caux-Moncoutier V, Fassy-Colcombet M, Cornelis F, Mazoyer S, Leone M, Boutry-Kryza N, Hardouin A, Berthet P, Muller D, Fricker JP, Mortemousque I, Pujol P, Coupier I, Lebrun M, Kientz C, Longy M, Sevenet N, Stoppa-Lyonnet D, Isaacs C, Caldes T, de la Hoya M, Heikkinen T, Aittommaki K, Blanco I, Lazaro C, Barkardottir RB, Soucy P, Dumont M, Simard J, Montagna M, Tognazzo S, D'Andrea E, Fox S, Yan M, Rebbeck T, Olopade O, Weitzel JN, Lynch HT, Ganz PA, Tomlinson GE, Wang X, Fredericksen Z, Pankratz VS, Lindor NM, Szabo C, Offit K, Sakr R, Gaudet M, Bhatia J, Kauff N, Singer CF, Tea MK, Gschwantler-Kaulich D, Fink-Retter A, Mai PL, Greene MH, Imyanitov E, O'Malley FP, Ozcelik H, Glendon G, Toland AE, Gerdes AM, Thomassen M, Kruse TA, Jensen UB, Skytte AB, Caligo MA, Soller M, Henriksson K, Wachenfeldt vA, Arver B, Stenmark-Askmalm M, Karlsson P, Ding YC, Neuhasuen SL, Beattie M, Pharoah PD, Moysich KB, Nathanson KL, Karlan BY, Gross J, John EM, Daly MB, Buys SM, Southey MC, Hopper JL, Terry MB, Chung W, Miron AF, Goldgar D, Chenevix-Trench G, Easton DF, Andrulis IL, Antoniou AC; Breast Cancer Family Registry; EMBRACE; GEMO Study Collaborators; HEBON; kConFab Investigators; Ontario Cancer Genetics Network; SWE-BRCA; CIMBA. Common breast cancer susceptibility alleles are associated with tumour subtypes in BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2., Breast Cancer Research, 13(6), R110, 2011
  • Juhasz A, Mittal SK, Lee TH, Deng C, Chak A, Lynch HT. Prevalence of Barrett esophagus in first-degree relatives of patients with esophageal adenocarcinoma., J Clinical Oncology, 45(10), 867-71, 2011
  • Lynch HT, Riegert-Johnson DL, Snyder C, Lynch JF, Hagenkord J, Boland CR, Rhees J, Thibodeau SN, Boardman LA, Davies J, Kuiper RP, Hoogerbrugge N, Ligtenerg MJ. Lynch syndrome-associated extracolonic tumors are rare in two extended families with the same EPCAM deletion., Am J Gastroenterol, 106(10), 1829-36, 2011
  • Rebecck TR, Mitra N, Domchek SM, Wan F, Friebel TM, Tran TV, Singer CF, Tea MK, Blum JL, Tung N, Olopade OI, Weitzel JN, Lynch HT, Snyder CL, Garber JE, Antoniou AC, Peock S, Evans DG, Paterson J, Kennedy MJ, Donaldson A, Dorkins H, Easton DF; Epidemiological Study of BRCA1 and BRCA2 Mutation Carriers (EMBRACE), Rubinstein WS, Daly MB, Isaacs C, Nevanlinna H, Couch FJ, Andrulis IL, Freidman E, Laitman Y, Ganz PA, Tomlinson GE, Neuhausen SL, Narod SA, Phelan CM, Greenberg R, Nathanson KL. Modification of BRCA1-Associated Breast and Ovarian Cancer Risk by BRCA1-Interacting Genes., Cancer Research, 71(17), 5792-805, 2011
  • Neuhausen SL, Brummel S, Ding YC, Steele L, Nathanson KL, Domchek S, Rebbeck TR, Singer CF, Pfeiler G, Lynch HT, Garber JE, Couch F, Weitzel JN, Godwin A, Narod SA, Ganz PA, Daly MB, Isaacs C, Olopade OI, Tomlinson GE, Rubinstein WS, Tung N, Blum JL, Gillen DL. Genetic variation in IGF2 and HTRA1 and breast cancer risk among BRCA1 and BRCA2 carriers., Cancer Epidemiol Biomarkers Prev, 20(8), 1690-702, 2011
  • Lynch HT, Lynch JF, Shaw TG. Hereditary gastrointestinal cancer syndromes., Gastrointest Cancer Res, 4(4 Suppl 1), S9-S17, 2011
  • Lynch HT, Lynch JF. Cigarette smoking and breast cancer risk., Womens Health (Lond Engl), 7(4), 413-6, 2011
  • Lubinski J, Huzarski T, Byrski T, Lynch HT, Cybulski C, Ghadirian P, Stawicka M, Foulkes WD, Kilar E, Kim-Sing C, Neuhausen SL, Armel S, Gilchrist D, Sweet K, Gronwald J, Eisen A, Gorski B, Sun P, Narod SA; the Hereditary Breast Cancer Clinical Study Group. The risk of breast cancer in women with a BRCA1 mutation from North America and Poland., Int. J. Cancer, 131(1), 229-234, 2011
  • Lynch HT, Riegert-Johnson DL, Snyder C, Lynch JF, Hagenkord J, Boland CR, Rhees J, Thibodeau SN, Boardman LA, Davies J, Kuiper RP, Hoogerbrugge N, Ligtenberg MJL. Lynch syndrome associated extracolonic tumors are rare in two extended families with the same EPCAM deletion., Am J Gastroenterol, In Press, 2011
  • Grass S, Klaus-Dieter P, Thome S, Weisenburger DD, Witt V, Lynch J, Zettl F, Trumper L, Fadle N, Regitz E, Lynch H, Pfreundschuh M. Paraproteins of familial MGUS/multiple myeloma target family-typical antigens: hyperphosphorylation of autoantigens is a consistent finding in familial and sporadic MGUS/MM., Blood, In Press, 2011
  • Spurdle AB, Marquart L, McGuffog L, Healey S, Sinilnikova O, Wan F, Chen X, Beesley J, Singer CF, Dressler AC, Gschwantler-Kaulich D, Blum JL, Tung N, Weitzel J, Lynch H, Garer J, Easton DF, Peock S, Cook M, Oliver CT, Frost D, Conroy D, Evans DG, Lalloo F, Eeles R, Izatt L, Davidson R, Chu C, Eccles D, Selkirk CG, Daly M, Isaacs C, Stoppa-Lyonnet D, Sinilnikova OM, Buecher B, Belotti M, Mazoyer S, Barjhoux L, Verney-Pierre C, Lasset C, Dreyfus H, Pujol P, Collonge-Rame MA; for the GEMO Study Collaborators, Rookus MA, Verhoef S, Kriege M, Hoogerbrugge N, Ausems MG, van Os TA, Wijnen J, Devilee P, Meijers-Heijboer HE, Blok MJ, Heikkinen T, Nevanlinna H, Jakubowska A, Lubinski J, Huzarski T, Byrski T, Durocher F, Couch FJ, Lindor NM, Wang X, Thomassen M, Domchek S, Nathanson K, Caligo M, Jernstrom H, Liljegren A, Ehrencrona H, Karlsson P; for SWE-BRCA, Ganz PA, Olopade OI, Tomlinson G, Neuhausen S, Antoniou AC, Chenevix-Trench G, Rebbeck TR. Common Genetic Variation at BARD1 Is Not Associated with Breast Cancer Risk in BRCA1 or BRCA2 Mutation Carriers., Cancer Epidemiol Biomarkers Prev, 20, 1032-38, 2011
  • Warner E, Hill K, Causer P, Plewes D, Jong R, Yaffe M, Foulkes WD, Ghadirian P, Lynch H, Couch F, Wong J, Wright F, Sun P, and Narod SA. Prospective Study of Cancer Incidence in Women With a BRCA1 or BRCA2 Mutation Under Surveillance With and Without Magnetic Resonance Imaging., J Clinical Oncology, 29, 1664-69, 2011
  • Metcalfe K, Gersham S, Lynch HT, Ghadirian P, Tung N, Kim-Sing C, Olopade OI, Domchek S, McLennan J, Eisen A, Foulkes WD, Rosen B, Sun P and Narod SA. Predictors of contralateral breast cancer in BRCA1 and BRCA2 mutation carriers., British Journal of Cancer, 104, 1384-92, 2011
  • Bordeleau L, Lipscombe L, Lubinski J, Ghadirian P, Foulkes WD, Neuhausen S, Ainsworth P, Pollak M, Sun P, Narod SA, Hereditary Breast Cancer Clinical Study Group (Lynch HT, member). Diabetes and breast cancer among women with BRCA1 and BRCA2 mutations., Cancer, 117, 1812-8, 2011
  • Lynch HT, Lynch JF, Snyder CL, Riegert-Johnson D. EPCAM deletions, Lynch syndrome, and cancer risk., Lancet Oncology, 12, 5-6, 2011
  • Metcalfe K, Lynch HT, Ghadirian P, Tung N, Kim-Sing C, Olopade OI, Domchek S, Eisen A, Foulkes WD, Rosen B, Vesprini D, Sun P, Narod SA. Risk of ipsilateral breast cancer in BRCA1 and BRCA2 mutation carriers., Breast Cancer Research and Treatment, 127, 287-96, 2011
  • Sherman, S, Shats, O, Ketcham, MA, Anderson, MA, Whitcomb, DC, Lynch, HT, Ghiorzo, P, Rubinstein, SW, Sasson, AR, Grizzle, WE, Haynatzki, G, Feng, J, Sherman, A, Kinarsky, L, Brand, RE. PCCR: Pancreatic Cancer Collaborative Registry., Cancer Informatics, 10, 83-91, 2011
  • Crockett DG, Wagner DG, Holmang S, Johansson SL, Lynch HT. Upper urinary tract carcinoma in Lynch syndrome cases., Journal of Urology, 185, 1627-30, 2011
  • Lynch HT, Snyder CL, Lynch JF, Thomé S. Familial plasma cell disorders and associated cancers. Clin Lymphoma Myeloma Leuk., Clin Lymphoma Myeloma Leuk, 11, 80-81, 2011
  • Lynch, HT, Lynch, JA, Shaw, TG. The History of Herediary Cancer. Cancer Hereditario, Sociedad Espanolade Oncoogia Medica., Not Applicable, 2nd Edition, 21-68, 2011
  • Ramus SJ, Kartsonaki C, Gayther SA, Pharoah PD, Sinilnikova OM, Beesley J, Chen X, McGuffog L, Healey S, Couch FJ, Wang X, Fredericksen Z, Peterlongo P, Manoukian S, Peissel B, Zaffaroni D, Roversi G, Barile M, Viel A, Allavena A, Ottini L, Papi L, Gismondi V, Capra F, Radice P, Greene MH, Mai PL, Andrulis IL, Glendon G, Ozcelik H; OCGN, Thomassen M. Gerdes AM, Kruse TA, Cruger D, Jensen UB, Caligo MA, Olsson H, Kristoffersson U, Lindblom A, Arver B, Karlsson P, Stenmark Askmalm M, Borg A, Neuhausen SL, Ding YC, Nathanson KL, Domchek SM, Jakubowska A, Lubinski J, Huzarski T, Byrski T, Gronwald J, Gorski B, Cybulski C, Debniak T, Osorio A, Duran M, Tejada MI, Benitez J, Hamann U, Rookus MA, Verhoef S, Tilanus-Linthorst MA, Vreeswijk MP, Bodmer D, Ausems MG, van Os TA, Asperen CJ, Blok MJ, Meijers-Heijboer HE; HEBON; EMBRACE, Peock S, Cook M, Oliver C, Frost D, Dunning AM, Evans DG, Eeles R, Pichert G, Cole T, Hodgson S, Brewer C, Morrison PJ, Porteous M, Kennedy MJ, Rogers MT, Side LE, Donaldson A, Gregory H, Godwin A, Stoppa-Lyonnet D, Moncoutier V, Castera L, Mazoyer S, Barjhoux L, Bonadona V, Leroux D, Faivre L, Lidereau R, Nogues C, Bignon YJ, Prieur F, Collonge-Rame MA, Venat-Bouvet L, Fert-Ferrer S; GEMO Study Collaborators, Miron A, Buys SS, Hopper JL, Daly MB, John EM, Terry MB, Goldgar D; BCFR, Hansen TO, Jonson L, Ejlertsen B, Agnarsson BA, Offit K, Kirchhoff T, Vijai J, Dutra-Clarke AV, Przybylo JA, Montagna M, Casella C, Imyanitov EN, Janavicius R, Blanco I, Lazaro C, Moysich KB, Karlan BY, Gross J, Beattie MS, Schmutzler R, Wappenschmidt B, Meindl A, Ruehl I, Fiebig B, Sutter C, Arnold N, Deissler H, Varon-Mateeva R, Kast K, Niederacher D, Gadzicki D, Caldes T, de la Hoya M, Nevanlinna H, Aittomaki K, Simard J, Soucy P; kConFab Investigators, Spurdle AB, Holland H, Chenevix-Trench G, Easton DF, Antoniou AC; Consortium of Investigators of Modifiers of BRCA1/2 (Lynch HT, member). Genetic variation at 9p22.2 and ovarian cancer risk for BRCA1 and BRCA2 mutation carriers., J Natl Cancer Inst, 103, 105-16, 2011
  • Lynch, HT, Jascur, T, Lanspa, S, Boland, CR. Making Sense of Missense in Lynch Syndrome: The Clinical Perspective., Cancer Prev Res, 3, 1371-1374, 2010
  • Lynch, HT, Lynch, JF, Lanspa, SJ. Familial Pancreatic Cancer., Cancers, 2, 1861-1883, 2010
  • Dennis J, Ghadirian P, Little J, Lubinski J, Gronwald J, Kim-Sing C, Foulkes W, Moller P, Lynch HT, Neuhausen SL, Domchek S, Armel S, Isaacs C, Tung N, Sweet K, Ainsworth P, Sun P, Krewski D, Narod S; Hereditary Breast Cancer Clinical Study Group. Alcohol consumption and the risk of breast cancer among BRCA1 and BRCA2 mutation carriers, The Breast Journal, 19, 479-83, 2010
  • Lynch, HT, Lynch JF. Hereditary diffuse gastric cancer: lifesaving total gastrectomy for CDH1 mutation carriers., J Med Genet, 47, 433-435, 2010
  • Antoniou AC, Beesley J, McGuffog L, Sinilnikova OM, Healey S, Neuhausen SL, Ding YC, Rebbeck TR, Weitzel JN, Lynch HT, Isaacs C, Ganz PA, Tomlinson G, Olopade OI, Couch FJ, Wang X, Lindor NM, Pankratz VS, Radice P, Manoukian S, Peissel B, Zaffaroni D, Barile M, Viel A, Allvena A, Dall’Olio V, Peterlongo P, Szabo CI, Zikan M, Claes K, Poppe B, Foretova L, Mai PL, Greene MH, Rennert G, Lejbkowicz F, Glendon G, Ozcelik H, Andrulis IL for the Ontario Cancer Genetics Network, Thomassen M, Gerdes A-M, Sunde L, Cruger D, Jensen UB, Caligo M, Friedman E, Kaufman B, Laitman Y, Milgrom R, Dubrovsky M, Cohen S, Borg A, Jernstrom H, Lindblom A, Rantala J, Stenmark-Askmalm M, Melin B for SWE-BRCA, Nathanson K, Domchek S, Jakubowska A, Lubinski J, Huzarski T, Osorio A, Lasa A, Duran M, Tejada M-I, Godino J, Benitez J, Hamann U, Kriege M, Hoogerbrugge N, van der Luijt RB, van Asperen CJ, Devilee P, Meijers-Heijboer EJ, Blok MJ, Aalfs CM, Hogervorst F, Rookus M for HEBON, Cook M, Oliver C, Frost D, Conroy D, Evans DG, Lalloo F, Pichert G, Davidson R, Cole T, Cook J, Paterson J, Hodgson S, Morrison PJ, Porteous ME, Walker L, Kennedy MJ, Dorkins H, Peock S for EMBRACE, Godwin AK, Stoppa-Lyonnet D, de Pauw A, Mazoyer S, Bonadona V, Lasset C, Dreyfus H, Leroux D, Hardouin A, Berthet P, Faivre L for GEMO, Loustalot C, Noguchi T, Sobol H, Rouleau E, Nogues C, Frenay M, Venat-Bouvet L for GEMO, Hopper JL, Daly MB, Terry MB, John EM, Buys SS, Yassin Y, Miron A, Goldgar D for the Breast Cancer Family Registry, Singer CF, Dressler AC, Gschwantler-Kaulich D, Pfeiler G, Hansen TVO, Jnson L, Agnarsson BA, Kirchhoff T, Offit K, Devlin V, Dutra-Clarke A, Piedmonte M, Rodriguez GC, Wakeley K, Boggess JF, Basil J, Schwartz PE, Blank SV, Toland AE, Montagna M, Casella C, Imyanitov E, Tihomirova L, Blanco I, Lazaro C, Ramus SJ, Sucheston L, Karian BY, Gross J, Schmutzler R, Wappenschmidt B, Engel C, Meindl A, Magdalena L, Arnold N, Heidermann S, Varon-Mateeva R, Niederacher D, Sutter C, Deissler H, Gadzicki D, Preisler-Adams S, Kast K, Schonbuchner I, Caldes T, de la Hoya M, Aittomaki K, Nevanlinna H, Simard J, Spurdle AB, Holland H, Chen X for kConFab, Platte R, Chenevix-Trench G, and Easton DF on behalf of CIMBA. Common Breast Cancer Susceptibility Alleles and the Risk of Breast Cancer for BRCA1 and BRCA2 Mutation Carriers: Implications for Risk Prediction., Cancer Research, 70, 9742-54, 2010
  • Lynch, HT. Cigarette Smoking and Breast Cancer Risk: Limited Evidence of Genotypic and Exogenous Carcinogenic Factors and Their Interactions., The Breast Journal, 16, 341-343, 2010
  • Domchek SM, Friebel TM, Garber JE, Isaacs C, Matloff E, Eeles R, Evans DG, Rubinstein W, Singer CF, Rubin S, Lynch HT, Daly MB, Weitzel J, Ganz PA, Pichert G, Olopade OI, Tomlinson G, Tung N, Blum JL, Couch F, Rebbeck TR. Occult ovarian cancers identified at risk-reducing salpingo-oophorectomy in a prospective cohort of BRCA1/2 mutation carriers., Breast Cancer Research and Treatment, 124, 195-203, 2010
  • Metcalf K, Lubinski J, Lynch HT, Ghadirian P, Foulkes WD, Kim-Sing C, Neuhausen S, Tung N, Rosen B, Gronwald J, Ainsworth P, Sweet K, Eisen A, Sun P, Narod SA; Hereditary Breast Cancer Clinical Study Group. Family History of cancer and cancer risks in women with BRCA1 and BRCA2 mutations., J Natl Cancer Inst, 102, 1874-8, 2010
  • Gaudet MM, Kirchhoff T, Green T, Vijai J, Korn JM, Guiducci C, Segre AV, McGee K, McGuffog L, Kartsonaki C, Morrison J, Healey S, Sinilnikova OM, Stoppa-Lyonnet D, Mazoyer S, Gauthier-Villars M, Sobol H, Longy M, Frenay M, GEMO Study Collaborators, Hogervorst FB, Rookus MA, Collee JM, Hoogerbrugge N, van Roozendaal KE; HEBON Study Collaborators, Piedmonte M, Rubinstein W, Nerenstone S, Van Le L, Blank SV, Caldes T, de la Hoya M, Nevanlinna H, Aittomaki K, Lazaro C, Blanco I, Arason A, Johannsson OT, Barkardottir RB, Devilee P, Olopade OI, Neuhausen SL, Wang X, Fredericksen ZS, Peterlongo P, Manoukian S, Barile M, Viel A, Radice P, Phelan CM, Narod S, Rennert G, Lejbkowicz F, Flugelman A, Andrulis IL, Glendon G, Ozcelik H; OCGN, Toland AE, Montagna M, D’Andrea E, Friedman E, Laitman Y, Borg A, Beattie M, Ramus SJ, Domchek SM, Nathanson KL, Rebbeck T, Spurdle AB, Chen X, Holland H; kConFab, John EM, Hopper JL, Buys SS, Daly MB, Southey MC, Terry MB, Tung N, Overeem Hansen TV, Nielsen FC, Greene MH, Mai PL, Osorio A, Duran M, Andres R, Benitez J, Weitzel JN, Garber J, Hamann U, EMBRACE, Peock S, Cook M, Oliver C, Frost D, Platte R, Evans DG, Lalloo F, Eeles R, Izatt L, Walker L, Eason J, Barwell J, Godwin AK, Schmutzler RK, Wappenschmidt B, Engert S, Arnold N, Gadzicki D, Dean M, Gold B, Klein RJ, Couch FJ, Chenevix-Trench G, Easton DF, Daly MJ, Antoniou AC, Altshuler DM, Offit K, Sinilnikova OM, Stoppa-Lyonnet D, Mazoyer S, Gauthier-Villars M, Sobol H, Longy M, Frenay M, Sinilnikova O, Barjhoux L, Giraud S, Leone M, Mazoyer S, Stoppa-Lyonnet D, Gauthier-Villars M, Houdayer C, Moncoutier V, Belotti M, de Pauw A, Bressac-de-Paillerets B, Remenieras A, Byrde V, Caron O, Lenoir G, Bignon YJ, Uhrhammer N, Lasset C, Bonadona V, Hardouin A, Berthet P, Sobol H, Bourdon V, Noguchi T, Eisinger F, Coulet F, Colas C, Soubrier F, Coupier I, Peyrat JP, Fournier J, Revillion F, Vennin P, Adenis C, Rouleau E, Lidereau R, Demange L, Nogues C, Muller D, Fricker JP, Longy M, Sevenet N, Toulas C, Guimbaud R, Gladieff L, Feillel V, Leroux D, Dreyfus H, Rebischung C, Cassini C, Faivre L, Prieur F, Ferrer SF, Frenay M, Venat-Bouvet L, Lynch HT, Hogervorst FB, Rookus MA, Collee JM, Hoogerbrugge N, van Roozendaal KE, Hogervorst FB, Verhoef S, Verheus M, van ‘t Veer LJ, van Leeuwen FE, Rookus MA, Collee M, van den Ouweland AM, Jager A, Hooning MJ, Tilanus-Linthorst MM, Seynaeve C, van Asperen CJ, Wijnen JT, Vreeswijk MP, Tollenaar RA, Devilee P, Ligtenberg MJ, Hoogerbrugge N, Ausems MG, van der Luijt RB, Aalfs CM, van Os TA, Gille JJ, Waisfisz Q, Meijers-Heijboer H, Gomez-Garcia EB, van Roozendaal CE, Blok MJ, Oosterwijk JC, van der Hout AH, Mourits MJ, Vasen HF, Spurdle AB, Chenevix-Trench G. Common genetic variants and modification of penetrance of BRCA2-associated breast cancer., PLoS Genetics, 6, e1001183, 2010
  • Drescher KM, Sharma P, Lynch HT. Current Hypotheses on How Microsatellite Instability Leads to Enhanced Survival of Lynch Syndrome Patients. Clinical and Developmental Immunology., Clinical and Developmental Immunology, 1-13, 2010
  • Lynch, HT, Snyder, CS, Davies, JM, Lanspa, S, Lynch, J, Gatalica, Z, Graeve, V, Foster, J. FAP, Gastric cancer, and genetic counseling featuring children and young adults: a family study and review., Familial Cancer, 9, 581-588, 2010
  • Domchek SM, Friebel TM, Singer CF, Evans DG, Lynch HT, Isaacs C, Garber JE, Neuhausen SL, Matloff E, Eeles R, Pichert G, Van t’veer L, Tung N, Weitzel JN, Couch FJ, Rubinstein WS, Ganz PA, Daly MB, Olopade OI, Tomlinson G, Schildkraut J, Blum JL, Rebbeck TR. Association of risk-reducing surgery in BRCA1 or BRCA2 mutation carriers with cancer risk and mortality., J.A.M.A., 304, 967-75, 2010
  • Ginsburg OM, Kim-Sing C, Foulkes WD, Ghadirian P, Lynch HT, Sun P, Narod SA; Hereditary Breast Cancer Clinical Study Group. BRCA1 and BRCA2 families and the risk of skin cancer., Familial Cancer, 9, 489-93, 2010
  • Wagner DG, Gatalica Z, Lynch HT, Kohl S, Johansson SL, Lele SM. Neuroendocrine-type prostatic adenocarcinoma with microsatellite instability in a patient with lynch syndrome., Surg Pathol, 18, 550-3, 2010
  • Nabilsi NH, Broaddus RR, McCampbell AS, Lu KH, Lynch HT, Chen LM, Loose DS. Sex hormone regulation of survivin gene expression., Journal of Endocrinology, 207, 237-43, 2010
  • Pal T, Keefe D, Sun P, Narod SA; Hereditary Breast Cancer Clinical Study Group; Fertility in women with BRCA mutations: a case-control study., Fertility & Sterility, 93(6), 1805-8, 2010
  • Cunningham D, AtkinW, Lenz HJ, Lynch HT, Minsky B, Nordlinger B, Starling N.; Colorectal Cancer, Lancet, 375(9719), 1030-47, 2010
  • Domchek SM, Friebel TM,Garber JE, Isaacs C, Matloff E, Eeles R, Evans DG, Rubinstein W, Singer CF, Rubin S, Lynch HT et al.; Occult ovarian cancers identified at risk-reducing salpingo-oophorectomy in a prospective cohort of BRCA1/2 muations carriers., Breast Cancer Research and Treatment, 2010
  • Natarajan N, Watson P, Silva-Lopez E, Lynch HT; Comparison of extended colectomy and limited resection in patients with Lynch syndrome., Diseases of the Colon & Rectum, 53(1), 77-82, 2010
  • Bellacosa A, Godwin AK, Peri S, Devarajan K, Caretti E, Vanderveer L, Bove B, Slater C, Zhou Y, Daly M, Howard S, Campbell KS, Nicolas E, Yeung AT, Clapper ML, Crowell JA, Lynch HT, et al.; Altered gene expression in morphologically normal epithelial cells from heterozygous carriers of BRCA1 or BRCA2 mutations., Cancer Prev Res, 3(1), 48-61, 2010
  • Osorio A et al; Evaluation of a candidate breast cancer associated SNP in ERCC4 as a risk modifer in BRCA1 and BRCA2 mutation carriers. Results from the Consortium of Investigators of Modifiers of BRCA1/BRCA2 (CIMBA), British Journal of Cancer, 101(12), 2048-54, 2009
  • Coleman EA, Lynch H, Enderlin C, Stewart B, Thome SD, Kennedy R, Richardson-Nelson T, Barlogie B.; Initial report of a family registry of multiple myeloma., Cancer Nursing, 32(6), 456-64, 2009
  • Neuhausen SL, Brummel S, Ding YC, Singer CF, Pfeiler G, Lynch HT, et al.; Genetic variation in insulin-like growth factor signaling genes and breast cancer risk among BRCA1 and BRCA2 carriers., Breast Cancer Research, 11(5), R76, 2009
  • Antoniou AC, et al.; Common variants in LSPl, 2q35 and 8q24 and breast cancer risk for BRCA1 and BRCA2 mutation carriers., Human Molecular Genetics, 18(22), 4442-56, 2009
  • Ginsburg OM, Akbari MR, Aziz Z, Young r, Lynch H, et al.; The prevalence of germ-line TP53 mutations in women diagnosed with breast cancer before age 30., Familial Cancer, 8(4), 563-7, 2009
  • Lynch, HT, Thome S; MGUS, multiple myeloma, and paratarg-7., Lancet Oncology, 10(10, 931-2, 2009
  • Snyder CL, Lynch JF, Lynch HT; Genetic counseling and the advanced practice oncology nursing role in a hereditary cancer prevention clinic: hereditary breast cancer focus (part I)., The Breast Journal, Suppl 1, S2-10, 2009
  • Lynch HT, Snyder CL, Lynch JF; Genetic counseling and the advanced practice oncology nursing role in a hereditary cancer prevention clinic: hereditary breast cancer focus (part II)., The Breast Journal, Suppl 1, S11-9, 2009
  • Vicus D, Rosen B, Lubinski J, Domchek S, Kauff ND, Lynch HT, Isaacs C, Tung N, Sun P, Narod SA; Hereditary Ovarian Cancer Clinical Study Group; Tamoxifen and the risk of ovarian cancer in BRCA1 mutation carriers., Gynecologic Oncology, 115(1), 135-7, 2009
  • Lynch HT, Snyder CL, Lynch JF, Ghate S, Narod SA, Gong G; Family information service participation increases the rates of mutation testing among members of families with BRCA1/2 mutations., The Breast Journal, Suppl 1, S20-4, 2009
  • Salipante SJ, Mealiffe ME, Wechsler J, Krem MM, Liu Y, Namkoong S, Bhagat G, Kirchhoff T, Offit K, Lynch H, et al.; Mutations in a gene encoding a midbody kelch protein in familial and sporadic classical Hodgkin lymphoma lead to binucleated cells., Proceedings of the National Academy of Sciences, 106(35), 14920-5, 2009
  • Lynch HT, Lynch JF, Attard TA; Diagnosis and mangement of hereditary colorectal cancer syndromes: Lynch syndrome as a model., CMAJ, 181(5), 273-80, 2009
  • Watson P, Lieberman R, Synder C, Clark FJ, Lynch HT, Holt JT. Detecting BRCA2 Protein truncation in Tissue Biopsies to Identify Breast Cancers That Arise in BRCA2 Gene Mutation Carrires., Clinical Oncology, 27:24, 3894-3900, 2009
  • Lynch HT, Marcus JN, Lynch J, Synder CL, Rubinstein WS. Chapter 21 – Breast Cancer Genetics: Syndromes, Genes, Pathology, Counseling, Testing, and Treatment. The Breast - Bland & Copeland, Not Applicable, 1, 371-415, 2009
  • Lynch HT, Thome SD; Familial multiple myeloma, Blood, 114(4), 749-50, 2009
  • Lynch HT, Lynch PM, Lanspa SJ, Snyder CL, Lynch JF, Boland CR. Review of the Lynch syndrome: history, molecular genetics, screening differential diagnosis, and medicolegal ramifications, Clinical Genetics, 76, 1-18, 2009
  • Rebbeck TR, Mitra N, Domchek SM, Wan F, Chuai S, Friebel TM, Panossian S, Spurdle A, Chenevix-Trench G; kConFab, Singer CF, Pfeiler G, Neuhausen SL, Lynch HT, et al.; Modification of ovarian cancer risk by BRCA1/2-interacting genes in a multicenter cohort of BRCA1/2 mutation carriers., Cancer Research, 69(14), 5801-10, 2009
  • Nakagawa H, Nagasaka T, Cullings HM, Notohara K, Hoshijima N, Young J, Lynch HT, Tanaka N, Matsubara N. Efficient molecular screening of Lynch syndrome by specific 3’ promoter methylation of the MLH1 or BRAF mutation in colorectal cancer with high-frequency microsatellite instability., Oncology Reports, 21(6), 1577-83, 2009
  • Lynch HT, Shaw TG. Commentary: The shifting role of family history in Lynch syndrome diagnosis., Association of Coloproctology of Great Britian and Ireland, 11(5), 461-3, 2009
  • Lynch HT, Casey MJ, Snyder CL, Bewtra C, Lynch JF, Butts M, Godwin AK. Hereditary ovarian carcinoma: heterogeneity, molecular genetics, pathology, and management., Molecular Oncology, 3(2), 97-137, 2009
  • Ginsburg O, Ghadirian P, Lubinski J, Cybulski C, Lynch H, Neuhausen S, Kim-Sing C, Robson M, Domchek S, Isaacs C, Klijn J, Armel S, Foulkes WD, Tung N, Moller P, Sun P, Narod SA, Hereditary Breast Cancer Clinical Study Group. Smoking and the risk of breast cancer in BRCA1 and BRCA2 carriers: an update., Breast Cancer Research and Treatment, 114, 127-135, 2009
  • Drescher KM, Sharma P, Watson P, Gatalica Z, Thibodeau SN, Lynch HT. Lymphocyte recruitment into the tumor site is altered in patients with MSI-H colon cancer, Familial Cancer, Epub ahead of print, Epub ahead of print, 2009
  • Akbari MR, Ghadirian P, Robidoux A, Foumani M, Sun Y, Royer R, Zandvakili I, Lynch H, Narod SA. Germline RAP80 mutations and susceptibility to breast cancer., Breast Cancer Research and Treatment, 113, 377-381, 2009
  • Greer JB, Lynch HT, Brand RE. Hereditary pancreatic cancer: A clinical perspective., Research Clinical Gastroenterology, 23, 2, 2009
  • Burn J, Bishop T, Mecklin J-P, Macrae F, Möslein G, Olschwang S, Bisgaard M-L, Ramesar R, Eccles D, Maher E.R., Bertario L, Jarvinen HJ, Lindblom A, Evans, DG, Lubinski J, Morrison PJ, Ho JWC, Vasen HFA, Side L, Thomas HJW, Scott RJ, Dunlop M, Barker G, Elliott F, Jass JR, Fodde R, Lynch HT, and Mathers JC, for the CAPP2 Investigators. Effect of Aspirin or Resistant Starch on Colorectal Neoplasia in the Lynch Syndrome., New England Journal of Medicine, 359(24), 2567-78, 2008
  • Kotsopoulos J, Librach CL, Lubinski J, Gronwald J, Kim-Sing C, Ghadirian P, Lynch HT, Moller P, Foulkes WD, Randall S, Manoukian S, Pasini B, Tung N, Ainsworth PJ, Cummings S, Sun P, Narod SA; Hereditary Breast Cancer Clincial Study Group. Infertility, treatment of infertility, and the risk of breast cancer among women with BRCA1 and BRCA2 mutations: a case-control study., Cancer Causes Control, 19(10), 1111-9, 2008
  • Schwartz GF, Hughes KS, Lynch HT, Fabian CJ, Fentiman IS, Robson ME, Domchek SM, Hartmann LC, Holland R, Winchester DJ, and the Consensus Conference Committee. Proceedings of the International Consensus Conference on Breast Cancer Risk, Genetics, & Risk Management, April, 2007., Cancer, 113(10), 2627-37, 2008
  • Lynch HT, Ferrara KM, Weisenburger DD, Sanger WG, Lynch FJ, Thomé SD. Genetic counseling for DAPK1 mutation in a chronic lymphocytic leukemia family., Cancer Genetics and Cytogenetics, 186(2), 95-102, 2008
  • Eisen A, Lubinski J, Gronwald J, Moller P, Lynch HT, Klijn J, Kim-Sing C, Neuhausen SL, Gilbert L, Ghadirian P, Manoukian S, Rennert G, Friedman E, Isaacs C, Rosen E, Rosen B, Daly M, Sun P, Narod SA; Hereditary Breast Cancer Clincial Study Group. Hormone therapy and the risk of breast cancer in BRCA1 mutation carriers., J Natl Cancer Inst, 100(19), 1361-7, 2008
  • Lynch HT, Silva E, Wirtzfeld D, Hebbard P, Lynch JF, Huntsman D. Hereditary Diffuse Gastric Cancer: Prophylactic Surgical Oncology Implications., Surg Clin N Am, 88(4), 759-778, 2008
  • Narod SA, Neuhausen S, Vichodez G, Armel S, Lynch HT, Ghadirian P, Cummings S, Olopade O, Stoppa-Lyonnet D, Couch F, Wagner T, Warner E, Foulkes WD, Saal H, Weitzel J, Tulman A, Poll A, Nam R, Sun P, the Hereditary Breast Cancer Study Group. Rapid progression of prostate cancer in men with a BRCA2 mutation., Br J Cancer, 99(2), 371-4, 2008
  • Lynch HT, Ferrara K, Barlogie B, Coleman E, Lynch JF, Weisenburger D, Sanger W, Watson P, Nipper H, Witt V, Thomé S. Familial Myeloma., New England Journal of Medicine, 359(2), 152-7, 2008
  • Majewski T, Lee S, Jeong J, Yoon D-S, Kram A, Kim M-S, Tuziak T, Bondaruk J, Lee S, Park W-S, Tang KS, Chung W, Shen L, Ahmed SS, Johnston DA, Grossman HB, Dinney CP, Zhou J-H, Harris RA, Snyder C, Filipek S, Narod SA, Watson P, Lynch HT, Gazdar A, Bar-Eliu M, Wu XF, McConkey DJ, Baggerly K, Issa J-P, Benedict WF, Scherer SE, Czerniak B. Understanding the development of human bladder cancer by using a whole-organ genomic mapping strategy., Lab Invest, 88(7), 694-721, 2008
  • 30. Lynch HT, Lanspa SJ. Commentary on Lynch Syndrome and Related Familial Colorectal Cancers., Critical Reviews in Oncogenesis, 14, 23-31, 2008
  • Lynch HT, Kaurah P, Wirtzfeld D, Rubinstein WS, Weissman S, Lynch JF, Grady W, Wiyrick S, Senz J, Huntsman DG. Hereditary diffuse gastric cancer: diagnosis, genetic counseling, and prophylactic total gastrectomy, Cancer, 112(12), 2655-2663, 2008
  • Chao EC, Velasquez JL, Witherspoon MS, Rozek LS, Peel D, Ng P, Gruber SB, Watson P, Rennert g, Anton-Culver H, Lynch H, Lipkin SM. Accurate classification of MLH1/MSH2 missense variants with multivariate analysis of protein polymorphisms-mismatch repair (MAPP-MMR)., Hum Mutat, 29(6), 852-860, 2008
  • Lynch HT, Drescher KM, de la Chapelle A. Immunology and the Lynch syndrome, Gastroenterology, 134(4), 1246-1249, 2008
  • Clendenning M, Baze ME, Sun S, Walsh K, Liyanarachchi S, Fix D, Schunemann V, Comeras I, Deacon M, Lynch JF, Gong G, Thomas BC, Thibodeau SN, Lynch HT, Hampel H, de la Chapelle A. Origins and prevalence of the American Founder Mutation of MSH2, Cancer Research, 68(7), 2145-2153, 2008
  • Antoniou AC, Spurdle AB, Sinilnikova OM, Healey S. Pooley KA, Schmutzler RK, Versmold B, Engel C, Meindl A, Aronld N, Hofmann W, Sutter C, Niederacher D, Deissler H, Caldes T, Kämpjärvi K, Nevanlinna H, Simard J, Beesley J, Chen X; Kathleen Cuningham Consortium for Research into Familial Breast Cancer, Neuhausen SL, Rebbeck TR, Wagner T, Lynch HT, Isaacs C, Weitzel J, Ganz PA, Daly MB, Tomlinson G, Olopade OI, Blum JL, Couch FJ, Peterlongo P, Manoukian S, Barile M, Radice P, Szabo CI, Pereira LH, Greene MH, Rennert G, Lejbkowicz F, Barnett-Griness O, Andrulis IL, Ozcelik H; OCGN, Gerdes AM, Caligo MA, Laitman Y, Kaufman B, Milgrom R, Friedman E; Swedish BRCA1 and BRCA2 study collaborators, Domchek SM, Nathanson KL, Osorio A, Llort G, Milne RL, Benítez J, Hamann U, Hogervorst FB, Manders P, Ligtenberg MJ, van den Ouweland AM; DNA-HEBON collaborators, Peock S, Cook M, Platte R, Evans DG, Eeles R, Pichert G, Chu C, Eccles D, Davidson R, Douglas F; EMBRACE, Godwin AK, Barjhoux L, Mazoyer S, Sobol H, Bourdon V, Eisinger F, Chompret A, Capoulade C, Bressac-de Paillerets B, Lenoir GM, Gauthier-Villars M, Houdayer C, Stoppa-Lyonnet D; GEMO, Chenevix-Trench G, Easton DF; CIMBA. Common breast cancer-predisposition alleles are associated with breast cancer risk in BRCA1 and BRCA2 carriers, American Journal of Human Genetics, 82(4), 937-948, 2008
  • Zhang S, Phelan CM, Zhang P, Rousseau F, Ghadirian P, Robidoux A, Foulkes W, Hamel N, McCready D, Trudeau M, Lynch H, Horsman D, De Matsuda ML, Aziz Z, Gomes M, Costa MM, Liede A, Poll A, Sun P, Narod SA. Frequency of the CHEK2 1100delC mutation among women with breast cancer: an international study., Cancer Research, 68(7), 2154-2157, 2008
  • Tarafa G, Tuck D, Ladner D, Topazian M, Brand R, Deters C, Moreno V, Capella G, Lynch H, Lizardi P, Costa J. Mutational load distribution analysis yields metrics reflecting genetic instability during pancreatic carcinogenesis., Proceedings of the National Academy of Sciences, 105, 4306-4311, 2008
  • Kauff ND, Domchek SM, Friebel TM, Robson ME, Lee J, Garber JE, Isaacs C, Evans DG, Lynch H, Eeles RA, Neuhausen SL, Daly MB, Matloff E, Blum JL, Sabbatini P, Barakat RR, Hudis C, Norton L, Offit K, Rebbeck TR. Risk-reducing salpingo-oophorectomy for the prevention of BRCA1-and BRCA2-associated breast and gynecologic cancer: a multicenter, prospective study., J Clinical Oncology, 26, 1331-1337, 2008
  • Metcalfe KA, Lubinski J, Ghadirian P, Lynch H, Kim-Sing C, Friedman E, Foulkes WD, Domchek S, Ainsworth P, Isaacs C, Tung N, Gronwald J, Cummings S, Wagner T, Manoukian S, Mǿller P, Weitzel J, Sun P, Narod SA; Hereditary Breast Cancer Clinical Study Group. Predictors of contralateral prophylactic mastectomy in women with a BRCA1 or BRCA2 mutation: the Hereditary Breast Cancer Clinical Study Group., J Clinical Oncology, 26(7), 1093-1097, 2008
  • Attard TM, Tajouri T, Peterson KD, Tinley S, Thorson AG, Lynch HT. Familial adenomatous polyposis in children younger than age ten years: a multidisciplinary clinic experience, Diseases of the Colon & Rectum, 51(2), 207-212, 2008
  • Lynch HT, Silva E, Snyder C, Lynch JF. Hereditary breast cancer: part I. Diagnosing hereditary breast cancer syndromes, The Breast Journal, 14(1), 3-13, 2008
  • Silva E, Gatalica Z, Snyder C, Vranic S, Lynch JF, Lynch HT. Hereditary breast cancer: part II. Management of hereditary breast cancer: implications of molecular genetics and pathology, The Breast Journal, 14(1), 14-24, 2008
  • Lynch HT, Lynch JF. How early to test for a cancer-causing germline mutation, Cancer Genetics and Cytogenetics, 180(1), 87-88, 2008
  • Lynch HT, Lynch JF. Lynch syndrome and the role of the registered nurse: commentary on “hereditary nonpolyposis colorectal cancer (Lynch syndrome): molecular pathogenesis and clinical approaches to diagnosis and management for nurses.”, Biol Res Nurs, 9(3), 200-202, 2008
  • Friebel TM, Domchek SM, Neuhausen SL, Wagner T, Evans DG, Isaacs C, Garber JE, Daly MB, Eeles R, Matloff E, Tomlinson G, Lynch HT, Tung N, Blum JL, Weitzel J, Rubinstein WS, Ganz PA, Couch F, Rebbeck TR. Bilateral prophylactic oophorectomy and bilateral prophylactic mastectomy in a prospective cohort of unaffected BRCA1 and BRCA2 mutation carriers., Clinical Breast Cancer, 7(11), 875-882, 2007
  • Antoniou AC, Sinilnikova OM, Simard J. Léoné M, Dumont M, Neuhausen SL, Struewing JP, Stoppa-Lyonnet D, Barjhoux L, Hughes DJ, Coupier I, Belotti M, Lasset C, Bonadona V, Bignon YJ; Genetic Modifiers of Cancer Risk in BRCA1/2 Mutation Carriers Study (GEMO), Rebbeck TR, Wagner T, Lynch HT, Domchek SM, Nathanson KL, Garber JE, Weitzel J, Narol SA, Tomlinson G, Olopade OI, Godwin A, Isaacs C, Jakubowska A, Lubinski J, Gronwald J, Górski B, Byrski T, Huzarski T, Peock S, Cook M, Baynes C, Murray A, Rogers M, Daly PA, Dorkins H; Epidemiological Study of BRCA1 and BRCA2 Mutation Carriers (EMBRACE), Schmutzler RK, Versmold B, Engel C, Meindl A, Arnold N, Niederacher D, Deissler H; German Consortium for Hereditary Breast and Ovarian Cancer (GCHBOC), Spurdle AB, Chen X, Waddell N, Cloonan N; Kathleen Cuningham Consortium for Research into Familial Breast Cancer (kConFab), Kirchhoff T, Offit K, Friedman E, Kaufmann B, Laitman Y, Galore G, Rennert G, Lejbkowicz F, Raskin L, Andrulis IL, Ilyushik E, Ozcelik H, Devilee P, Vreeswijk MP, Greene MH, Prindiville SA, Osorio A, Benitez J, Zikan M, Szabo CI, Kilpivaara O, Nevanlinna H, Hamann U, Durocher F, Arason A, Couch FJ, Easton DF, Chenevix-Trench G; Consortium of Investigators of Modifers of BRCA1/2 (CIMBA). RAD51 135GC modifies breast cancer risk among BRCA2 mutation carriers: results from a combined analysis of 19 studies, American Journal of Human Genetics, 81(6), 1186-1200, 2007
  • Kotsopoulos J., J. Lubinski, H.T. Lynch, J. Klijn, P. Ghadirian, S.L. Neuhausen, C. Kim-Sing, W.D. Foulkes, P. Moller, C. Isaacs, S. Domchek, S. Randall, K. Offit, N. Tung, P. Ainsworth, R. Gershoni-Baruch, A. Eisen, M. Daly, B. Karlan, H.M. Saal, F. Couch, B. Pasini, T. Wagner, E. Friedman, G. Rennert, C. Eng, J. Weitzel, P. Sun, S.A. Narod; The Hereditary Breast Cancer Clinical Study Group, Breast Cancer Research and Treatment, 105(2), 221-228, 2007
  • Brand RE, Lerch MM, Rubinstein WS, Neoptolemos JP, Whitcomb DC, Hruban RH, Brentnall TA, Lynch HT, Canto MI; Participants of the Fourth International Symposium of Inherited Diseases of the Pancreas. Advances in counseling and surveillance of patients at risk for pancreatic cancer, Gut, 56, 1460-1469, 2007
  • Vaccaro CA, Bonadeo F, Roverano AV, Peltomaki P, Bala S, Renkonen E, Redal MA, Mocetti E, Mullen E, Ojea-Quintana G, Benati ML, Rivello HG, Clark MB, Lynch JF, Lynch HT. Hereditary nonpolyposis colorectal cancer (Lynch Syndrome) in Argentina: report from a referral hospital register, Diseases of the Colon & Rectum, 50, 1604-1611, 2007
  • Van Domselaar F, Correa D, Vaccaro C, Redal M, Van Domselaar R, Huntsman D, Kaurah P, Senz J, Lynch H. Hereditary diffuse gastric cancer (HDGC): presentation of a family with a new mutation of the CDH1 gene., Acta Gastroenterol Latinoam, 37(3), 158-163, 2007
  • Gonzalez-Neira A., J.M. Rosa-Rosa, A. Osorio, E. Gonzalez, M. Southey, O. Sinilnikova, H. Lynch, R.A. Oldenburg, C.J. van Asperen, N. Hoogerbrugge, G. Pita, P. Devilee, D. Goldgar, J. Benitez. Genomewide high-density SNP linkage analysis of non-BRCA1/2 breast cancer families identifies various candidate regions and has greater power than microsatellite studies., BMC Genomics, 8(1), 299, 2007
  • Lynch H.T., C.R. Boland, M.A. Rodriguez-Bigas, C. Amos, J.F. Lynch, P.M. Lynch. Who should be sent for genetic testing in hereditary colorectal cancer syndromes?, Not Applicable, 25(23), 3534-42, 2007
  • Couch F.J., O. Sinilnikova, R.A. Vierkant, V.S. Pankratz, Z.S. Fredericksen, D. Stoppa-Lyonnet, I Coupier, D. Hughes, A. Hardouin, P. Berthet, S. Peock, M. Cook, C. Baynes, S. Hodgson, P.J. Morrison, M.E. Porteous, A. Jakubowska, J. Lubinski, J. Gronwald, A.B. Spurdle; kConFab, R. Schmutzler, B. Versmold, C. Engel, A. Meindl, C. Sutter, J. Horst, D. Schaefer, K. Offit, T. Kirchhoff, I.L. Andrulis, E. Ilyushik, G. Glendon, P. Devilee, M.P. Vreeswijk, H.F. Vasen, A. Borg, K. Backenhorn, J.P. Struewing, M.H. Greene, S.L. Neuhausen, T.R. Rebbeck, K. Nathanson, S. Domchek, T. Wagner, J.E. Garber, C. Szabo, M. Zikan, L. Foretova, J.E. Olson, T.A. Sellers, N. Lindor, H. Nevanlinna, J. Tommiska, K. Aittomaki, U. Hamann, M.U. Rashid, D. Torres, J. Simard, F. Durocher, F. Guenard, H.T. Lynch, C. Isaacs, J. Weitzel, O.I. Olopade, S. Narod, M.B. Daly, A.K. Godwin, G. Tomlinson, D.F. Easton, G. Chenevix-Trench, A.C. Antoniou; Consortium of Investigators of Modifiers of BRCA1/2., Cancer Epidemiol Biomarkers Prev, 16(7), 1416-21, 2007
  • Karuah P, MacMillan, A, Boyd N, Senz J, De Luca A, Chun N, Suriano G, Zaor S, Van Manen L, Gilpin C, Nikkel S, Connolly-Wilson M, Wissman S, Rubinstein WS, Sebold C, Greenstein R, Stroop J, Yim D, Panzini , McKinnon W, Greenblatt M, Wirtzfeld D, Fontaine D, Coit D, Yoon S, Chung D, Lauwers G, Pizzuti A, Vaccaro C, Redal MA, Oliveria C, Tischkowitz M, Olschwang S, Gallinger S, Lynch H, Green J, Ford J, Pharoah P, Fernandez B, Huntsman D. Founder and recurrent CDH1 mutations in families with hereditary diffuse gastric cancer., J.A.M.A., 297(21), 2360-2372, 2007
  • 20. Kaurah P, MacMillan A, Boyd N, Senz J, De Luca A, Chun N, Suriano G, Zaor S, Van Manen L, Gilpin C, Nikkel S, Connolly-Wilson M, Weissman S, Rubinstein WS, Sebold C, Greenstein R, Stroop J, Yim D, Panzini B, McKinnon W, Greenblatt M, Wirtzfeld D, Fontaine D, Coit D, Yoon S, Chung D, Lauwers G, Pizzuti A, Vaccaro C, Redal MA, Oliveira C, Tischkowitz M, Olschwang S, Gallinger S, Lynch H, Green J, Ford J, Pharoah P, Fernandez B, Huntsman D. Founder and recurrent CDH1 mutations in families with hereditary diffuse gastric cancer., J.A.M.A., 297, 2360-2372, 2007
  • 18. Raval A, Tanner SM, Byrd JC, Angerman EB, Perko JD, Chen SS, Hackanson B, Grever MR, Lucas DM Matkovic JJ, Lin TS, Kipps TJ, Murray F, Weisenburger D, Sanger W, Lynch J, Watson P, Jansen M, Yoshinaga Y, Rosenquist R, de Jong PJ, Coggill P, Beck S, Lynch H, de la Chapelle A, Plass C. Downregulation of death-associated protein kinase 1 (DAPK1) in chronic lymphocytic leukemia., Cell, 129, 879-890, 2007
  • 9. Kotsopoulos J, Ghadirian P, El-Sohemy A, Lynch HT, Snyder C, Daly M, Domchek S, Randall S, Karlan B, Zhang P, Zhang S, Sun P, Narod SA. The CYP1A2 genotype modifies the association between coffee consumption and breast cancer risk among BRCA1 mutation carriers., Cancer Epidemiol Biomarkers Prev, 16, 912-916, 2007
  • 8. Gong G, Kosoko-Lasaki S, Haynatzki G, Lynch HT, Lynch JA, Wilson MR. Inherited, familial and primary open-angle glaucoma., Journal of National Medical Associates, 99, 559-563, 2007
  • 10. Lynch HT, Fusaro RM, Lynch JF. Hereditary cancer syndrome diagnosis: molecular genetic clues and cancer control., Future Oncology, 3, 169-181, 2007
  • 11. Klein AP, de Andrade M, Hruban RH, Bondy M, Schwartz AG, Gallinger S, Lynch HT, Syngal S, Rabe KG, Goggins MG, Petersen GM. Linkage analysis of chromosome 4 in families with familial pancreatic cancer., Cancer Biology Therapy, 6, 320-323, 2007
  • 12. Lynch HT, Lynch JF, Lynch PM. Toward a consensus in molecular diagnosis of hereditary nonpolyposis colorectal cancer [editorial]., Journal of the National Cancer Institute, 99, 261-263, 2007
  • 13. Attard TM, Giglio P, Koppula S, Snyder C, Lynch HT. Brain tumors in individuals with familial adenomatous polyposis: a cancer registry experience and pooled case report analysis., Cancer, 109, 761-766, 2007
  • 14. Attard TM, Young RJ, Stoner JA, Lynch HT. Population differences in familial adenomatous polyposis may be an expression of geographic differences in APC mutation pattern., Cancer Genetics and Cytogenetics, 172, 180-182, 2007
  • 17. Beiner ME, Finch A, Rosen B, Lubinski J, Moller P, Ghadirian P, Lynch HT, Friedman E, Sun P, Narod SA, Hereditary Ovarian Cancer Clinical Study Group. The risk of endometrial cancer in women with BRCA1 and BRCA2 mutations. A prospective study., Gynecologic Oncology, 104, 7-10, 2007
  • Aoun, P., G.Zhou, W.C.Chan, C.Page, K.Neth, D.Pickering, W.Sanger, B.Quinn-Laquer, P.Watson, J.F.Lynch, H.T.Lynch, and D.D.Weisenburger. Familial B-cell chronic lymphocytic leukemia: Analysis of cytogenetic abnormalities, immunophenotypic profiles, and immunoglobulin heavy chain gene usage., American Journal of Clinical Pathology, 127(1), 31-38, 2007
  • 15. Howe JR, Haidle JL, Lal G, Bair J, Song C, Pechman B, Chinnathambi S, Lynch HT. ENG mutations in MADH4/BMPR1A mutation negative patients with juvenile polyposis., Clinical Genetics, 71, 91-92, 2007
  • 16. Narod SA, Lynch HT. CHEK2 mutation and hereditary breast cancer [editorial]., Clinical Oncology, 25, 6-7, 2007
  • Locker,G.Y., K.Kaul, D.S.Weinberg, Z.Gatalica, G.Gong, A.Peterman, J.Lynch, L.Klatzco, O.I.Olopade, C.A.Bomzer, A.Newlin, E.Keenan, M.Tajuddin, J.Knezetic, S.Coronel, H.T.Lynch. The I1307k APC polymorphism in Ashkenazi Jews with colorectal cancer: clinical and pathologic features., Cancer Genetics and Cytogenetics, 169(1), 33-38, 2006
  • Brand,R.M., D.D.Jones, H.T.Lynch, R.E.Brand, P.Watson, R.Ashwathnayaran, H.K.Roy. Risk of colon cancer in hereditary non-polyposis colorectal cancer patients as predicted by fuzzy modeling: Influence of smoking., World Journal of Gastroenterology, 12(28), 4485-4491, 2006
  • Finch, A., M.Beiner, J.Lubinski, H.T.Lynch, P.Moller, B.Rosen, J.Murphy, P.Ghadirian, E.Friedman, W.D.Foulkes, C.Kim-Sing, T.Wagner, N.Tung, F.Couch, D.Stoppa-Lyonnet, P.Ainsworth, M.Daly, B.Pasini, R.Gershoni-Baruch, C.Eng, O.I.Olopade, J.McLennan, B.Karlan, J.Weitzel, P.Sun, S.A.Narod, for the Hereditary Ovarian Cancer Clinical Study Group. Salpingo-oophorectomy and the risk of ovarian, fallopian tube, and peritoneal cancers in women with a BRCA1 or BRCA2 mutation., J.A.M.A., 296(2), 185-192, 2006
  • Smith,P., L.McGuffog, D.F. Easton, G.J.Mann, G.M.Pupo, B.Newman, G.Chenevix-Trench, C.Szabo, M.Southey, H.Renard, F.Odefrey, H.Lynch, D.Stoppa-Lyonnet, F.Couch, J.L.Hopper, G.G.Giles, M.R.E.M.McCredie, S.Buys, I.Andrulis, R.Senie, D.E.Goldgar, R.Oldenburg, K.Kroeze-Jansema, J.Kraan, H.Meijers-Heijboer, J.G.M.Klijn, C.van Asperen, I.van Leeuwen, H.F.A.Vasen, C.J.Cornelisse, P.Devilee, L.Baskcomb, S.Seal, R.Barfoot, J.Mangion, A.Hall, S.Edkins, E.Rapley, R.Wooster, J.Chang-Claude, D.Eccles, D.G.Evans, P.A.Futreal, K.L.Nathanson, B.L.Weber, N.Rahman, M.R.Stratton. A genome wide linkage search for breast cancer susceptibility genes., Genes Chromosomes Cancer, 45(7), 646-655, 2006
  • 4. Gronwald J, Tung N, Foulkes WD, Offit K, Gershoni R, Daly M, Kim-Sing C, Olsson H, Ainsworth P, Eisen A, Saal H, Friedman E, Olopade O, Osborne M, Weitzel J, Lynch H, Ghadirian P, Lubinski J, Sun P, Narod SA, The Hereditary Breast Cancer Clinical Study Group. Tamoxifen and contralateral breast cancer in BRCA1 and BRCA2 carriers: an update., Int. J. Cancer, 118, 2281-2284, 2006
  • Brand,R.E, H.T. Lynch. Genotype/phenotype of familial pancreatic cancer. In: Endocrinology and Metabolism Clinics of North America (Journal)., Not Applicable, 35(2), 405-415, 2006
  • Petersen, G.M., M. Andrade, M. Goggins, R.H. Hruban, M. Bondy, J.F. Korczak, S. Gallinger, H.T. Lynch, S. Syngal, K.G. Rabe, D. Seminara, A.P. Klein. Pancreatic Cancer Genetic Epidemiology Consortium., Cancer Epidemiol Biomarkers Prev, 15(4), 704-710, 2006
  • Lynch, H.T., C.R. Boland, G. Gong, T.G. Shaw, P.M. Lynch, R. Fodde, J.F. Lynch, A. de la Chapelle. Phenotypic and genotypic heterogeneity in the Lynch syndrome: Diagnostic, surveillance and management implications. In: European Journal of Human Genetics (journal), Not Applicable, 14(4), 390-402, 2006
  • Lynch,H.T., C.A.Deters, J.F.Lynch, R.Brand. Genetic disorders associated with exocrine and endocrine pancreatic tumors. In: Toxicology of the Pancreas. Pour,P.M. (ed.), CRC Press., Not Applicable, 491-518, 2006
  • Lynch, H.T., C. Snyder, J.F. Lynch, P. Karatoprakli, A. Trowonou, K. Metcalfe, S.A. Narod, G. Gong. Patient response to the disclosure of BRCA mutation tests in hereditary breast-ovarian cancer families., Cancer Genetics and Cytogenetics, 165(2), 91-97, 2006
  • Sinilnikova, O.M., S. Mazoyer, C. Bonnardel, H.T. Lynch, S.A. Narod, G.M. Lenoir. BRCA1 and BRCA2 mutations in breast and ovarian cancer syndrome: reflection on the Creighton University historical series of high risk families., Familial Cancer, 5(1), 15-20, 2006
  • Domchek, S.M., T.M. Friebel, S.L. Neuhausen, T. Wagner, G. Evans, C. Isaacs, J.E. Garber, M.B. Daly, R. Eeles, E. Matloff, G.E. Tomlinson, L. Van't Veer, H.T. Lynch, O.I. Olopade, B.L. Weber, T.R. Rebbeck. Mortality after bilateral salpingo-oophorectomy in BRCA1 and BRCA2 mutation carriers: A prospective cohort study., Lancet Oncology, 7(3), 223-229, 2006
  • Schmeler, K.M., H.T. Lynch, L-M. Chen, M.F. Munsell, P.T. Soliman, M.B. Clark, M.S. Daniels, K.G. White, S.G. Boyd-Rogers, P.G. Conrad, K.Y. Yang, M.M. Rubin, C.C. Sun, B.M. Slomovitz, D.M. Gershenson, K.H. Lu. Prophylactic surgery to reduce the risk of gynecologic cancers in the Lynch syndrome., New England Journal of Medicine, 354(3), 261-269, 2006
  • Lynch, H.T., A. de la Chapelle, H. Hampel, A. Wagner, R. Fodde, J.F. Lynch, R. Okimoto, M.B. Clark, S. Coronel, A. Trowonou, Y-X. Fu, G.R. Haynatzki, G. Gong. American founder mutation for Lynch syndrome: Prevalence estimates and implications., Cancer, 106(2), 448-452, 2006
  • Lynch,H.T., J.F. Lynch. Genetics, natural history, and DNA-based genetic counseling in hereditary breast cancer. Breast Cancer, Second Edition. Winchester,D.J., D.P.Winchester, C.A. Hudis, L.Norton (eds). B.C. Decker: Hamilton, Ontario., Not Applicable, 61-82, 2006
  • Broaddus,R.R., H.T. Lynch, L.M. Chen, M.S. Daniel, P. Conrad, M.F. Munsell, K.G. White, R. Luthra, K.H. Lu. Pathologic features of endometrial carcinoma associated with HNPCC: A comparison with sporadic endometrial carcinoma., Cancer, 106(1), 87-94, 2006
  • Nkondjock,A., P.Ghadirian, J.Kostopoulos, J.Lubinski, H.Lynch, C.Kim-Sing, D.Horsman, B.Rosen, C.Isaacs, B.Weber, W.Foulkes, P.Ainsworth, N.Tung, A.Eisen, E.Friedman, C.Eng, P.Sun, S.A.Narod. Coffee consumption and breast cancer risk among BRCA1 and BRCA2 mutation carriers., Int. J. Cancer, 118(1), 103-107, 2006
  • Cullinane, C.A., J. Lubinski, S.L. Neuhausen, P. Ghadirian, H.T. Lynch, C. Isaacs, B. Weber, P. Moller, K. Offit, C. Kim-Sing, E. Friedman, S. Randall, B. Pasini, P. Ainsworth, R. Gershoni-Baruch, W.D. Foulkes, J. Klijn, N. Tung, G. Rennert, O. Olopade, F. Couch, T. Wagner, H. Olsson, P. Sun, J.N. Weitzel, S.A. Narod. Effect of pregnancy as a risk factor for breast cancer in BRCA1/BRCA2 mutation carriers., Internation Journal of Cancer, 117(6), 988-991, 2005
  • Brose,M.S., T.C.Smyrk, H.T.Lynch. Genetic predisposition to cancer. In: Cancer Medicine, Edition 7. Kufe,D., R.Bast,Jr., W.Hait, W.Hong, R.Pollack, R.Weichselbaum, J.Holland, E.Frei,III. (eds.), B.C. Decker., Not Applicable, 2005
  • Douglas, J.A., S.B. Gruber, K.A. Meister, J. Bonner, P. Watson, A.J. Krush, H.T. Lynch. History and molecular genetics of Lynch syndrome in Family G: A century later. In: JAMA (journal), Not Applicable, 294(17), 2195-2202, 2005
  • Rebbeck, T.R., T. Friebel, T. Wagner, H.T. Lynch, J.E. Garber, M.B. Daly, C. Isaacs, O.I. Olopade, S.L. Neuhausen, L. van 't Veer, R. Eeles, D.G. Evans, G. Tomlinson, E. Matloff, S.A. Narod, A. Eisen, S. Domchek, K. Armstrong, B.L. Weber. Effect of short-term hormone replacement therapy on breast cancer risk reduction after bilateral prophylactic oophorectomy in BRCA1 and BRCA2 mutation carriers: The PROSE Study Group., J Clinical Oncology, 23(31), 7804-7810, 2005
  • Eisen,A., J. Lubinski, J. Klijn, P. Moller, H.T. Lynch, K. Offit, B. Weber, T. Rebbeck, S.L. Neuhausen, P. Ghadirian, W.D. Foulkes, R. Gershoni-Baruch, E. Friedman, G. Rennert, T. Wagner, C. Isaacs, C. Kim-Sing, P. Ainsworth, P. Sun, S.A. Narod. Breast cancer risk following bilateral oophorectomy in BRCA1 and BRCA2 mutation carriers: An international case-control study., J Clinical Oncology, 23(30), 7491-7496, 2005
  • van der Klift, H., J. Wijnen, A. Wagner, P. Verkuilen, C. Tops, R. Otway, M. Kohonen-Corish, H. Vasen, C. Oliani, D. Barana, P. Moller, C. DeLozier-Blanchet, P. Hutter, W. Foulkes, H. Lynch, J. Burn, G. Moslein, R. Fodde. Molecular characterization of the spectrum of genomic deletions in the mismatch repair genes MSH2, MLH1, MSH6, and PMS2 responsible for hereditary nonpolyposis colorectal cancer (HNPCC)., Genes Chromosomes Cancer, 44, 123-138, 2005
  • Lynch,H.T., J.Jass, J.F.Lynch, T.Attard. Hereditary colorectal cancer: An updated review. Part II: Lynch syndrome (hereditary nonpolyposis colorectal cancer). In: Gastroenterology & Hepatology (journal), Not Applicable, 1(2), 117-127, 2005
  • Jones,D.H., P.T.Silberstein, H.Lynch, C.Ternent. Regression of colorectal adenomas with intravenous cytotoxic chemotherapy in a patient with familial adenomatous polyposis., J Clinical Oncology, 23(25), 6278-6280, 2005
  • Kotsopoulos,J., O.I.Olopodo[sic], P.Ghadirian, J.Lubinski, H.T.Lynch, C.Isaacs, B.Weber, C.Kim-Sing, P.Ainsworth, W.D.Foulkes, A.Eisen, P.Sun, S.A.Narod. Changes in body weight and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers., Breast Cancer Research, 7(5), R833-R843, 2005
  • Suriano,G., S. Yew, P. Ferreira, J. Senz, P. Kaurah, J.M. Ford, T.A. Longacre, J.A. Norton, N. Chun, S. Young, M.J. Oliveira, B. MacGillivray, A. Rao, D. Sears, C.E. Jackson, J. Boyd, C. Yee, C. Deters, G.S. Pai, L.S. Hammond, B.J. McGivern, D. Medgyesy, D. Sartz, B. Arun, B.K. Oelschlager, M.P. Upton, W. Neufeld-Kaiser, O.E. Silva, T.R. Donenberg, D.A. Kooby, S. Sharma, B-A. Jonsson, H. Gronberg, S. Gallinger, R. Seruca, H. Lynch, D.G. Huntsman. Characterization of a recurrent germ line mutation of the E-cadherin gene: implications for genetic testing and clinical management., Clin Cancer Res, 11(15), 5401-5409, 2005
  • Metcalfe, K.A., W.D. Foulkes, H.T. Lynch, P. Ghadirian, N. Tung, I.A. Olivotto, E. Warner, O. Olopade, A. Eisen, B. Weber, J. McLennan, P. Sun, S.A. Narod. Effect of prior bilateral oophorectomy on the presentation of breast cancer in BRCA1 and BRCA2 mutation carriers., Hereditary Cancer in Clinical Practice, 3, 53-57, 2005
  • Metcalfe, K.A., C. Snyder, J. Siedel, D. Hanna, H.T. Lynch, S. Narod. The use of preventive measures among healthy women who carry a BRCA1 or BRCA2 mutation., Familial Cancer, 4, 97-103, 2005
  • Lynch, H.T., W. Grady, G. Suriano, D. Huntsman. Gastric cancer: new genetic developments. Journal of Surgical Oncology., Not Applicable, 90(3), 114-133, 2005
  • Merg, A., H.T. Lynch, J.F. Lynch, H.R. Howe. Hereditary colorectal cancer - part II. Current Problems in Surgery, Not Applicable, 42(5), 267-334, 2005
  • Drescher K.M., H.T. Lynch. Tumor infiltrating lymphocytes (TILs): lessons learned in 30 years of study. Clinical and Applied Immunology Reviews., Not Applicable, 5(3), 149-166, 2005
  • Casey, M.J., C. Snyder, C. Bewtra, S.A. Narod, P. Watson, H.T. Lynch. Intra-abdominal carcinomatosis after prophylactic oophorectomy in women of hereditary breast ovarian cancer syndrome kindreds associated with BRCA1 and BRCA2 mutations., Gynecologic Oncology, 97(2), 457-467, 2005
  • Lynch,H.T., J.Jass, J.F.Lynch, T.Attard. Hereditary colorectal cancer: An updated review. Part I: Hereditary polyposis syndromes. In: Gastroenterology & Hepatology (journal), Not Applicable, 1(1), 39-48, 2005
  • Lynch,H.T., J.F.Lynch. What the physician needs to know about Lynch syndrome: An update. In: Oncology(Williston) (journal), Not Applicable, 19(4), 455-469, 2005
  • Merg, A., H.T. Lynch, J.F. Lynch, J.R. Howe. Hereditary colon cancer - part I. Current Problems in Surgery., Not Applicable, 42(4), 195-256, 2005
  • Lu, K.H., M. Dinh, W. Kohlmann, P. Watson, J. Green, S. Syngal, P. Bandipalliam, L-M. Chen, B. Allen, P. Conrad, J. Terdiman, C. Sun, M. Daniels, T. Burke, D.M. Gershenson, H. Lynch, P. Lynch, R.R. Broaddus. Gynecologic cancer as a ”sentinel cancer” for women with hereditary nonpolyposis colorectal cancer syndrome., Obstetrics and Gynecology, 105(3), 569-574, 2005
  • Lynch,H.T., P. Watson, S. Tarantolo, P.H. Weirnik, B. Quinn-Laquer, K.I. Bergsagel, L. Huiart, O.I. Olopade, H. Sobol, W. Sanger, D. Hogg, D. Weisenburger. Phenotypic heterogeneity in multiple myeloma families., J Clinical Oncology, 23(4), 685-693, 2005
  • Lynch, H.T., C.A. Deters, C.L. Snyder, J.F. Lynch, P. Villeneuve, J Silberstein, H. Martin, S.A. Narod, R.E. Brand. BRCA1 and pancreatic cancer: pedigree findings and their causal relationships., Cancer Genetics and Cytogenetics, 158(2), 119-125, 2005
  • Metcalfe, K.A., H.T. Lynch, P. Ghadirian, N. Tung, I.A. Olivotto, W.D. Foulkes, E. Warner, O. Olopade, A. Eisen, B. Weber, J. McLennan, P. Sun, S.A. Narod. The risk of ovarian cancer after breast cancer in BRCA1 and BRCA2 carriers., Gynecologic Oncology, 96(1), 222-226, 2005
  • Watson, P., R. Ashwathnarayan, H.T. Lynch, H.K. Roy. Tobacco use and increased colorectal cancer risk in patients with hereditary nonpolyposis colorectal cancer (Lynch syndrome)., Arch Intern Med, 164(22), 2429-2431, 2004
  • Halbert,C.H., H.Lynch, J.Lynch, D. Main, S.Kucharski,A.K.Rustgi, and C. Lerman. Colon cancer screening practices following genetic testing for hereditary nonpolyposis colon cancer (HNPCC) mutations, Arch Intern Med, 164, 1881-1887, 2004
  • Lynch,H.T., S.T. Tinley, J.F. Lynch, and T.M. Attard. Challenging pedigrees seen in a hereditary cancer consultation center., Cancer Genetics and Cytogenetics, 153(2), 91-101, 2004
  • Lynch,H.T., T.G. Shaw, J.F. Lynch. Inherited predisposition to cancer: a historical overview. Am J Med Genet (Sem Med Genet)., Not Applicable, 129C(1), 5-22, 2004
  • Howe,J.R., M.G. Sayed, A.F. Ahmed, J. Ringold, J. Larsen-Haidle, A. Merg, F.A. Mitros, C.A. Vaccaro, G.M. Petersen, F.M. Giardiello, S.T. Tinley, L.A. Aaltonen, H.T. Lynch. The prevalence of MADH4 and BMPR1A mutations in juvenile polyposis and absence of BMPR2, BMPR1B, and ACVR1 mutations., J Med Genet, 41(7), 484-491, 2004
  • Lipkin, S.M., L.S. Rozek, G. Rennert, W. Yang, P-C. Chen, J. Hacia, N. Hunt, B. Shin, S. Fodor, M. Korkoris, J.K. Greenson, E. Fearon, H. Lynch, F. Collins, S.B. Gruber. The MLH1 D132H variant is associated with susceptibility to sporadic colorectal cancer., Nature Genetics, 36(7), 694-699, 2004
  • Lynch, H.T., J.F. Lynch. Lynch syndrome: history and current status. Disease Markers., Not Applicable, 20(4-5), 181-198, 2004
  • Lynch, H.T., W.S. Rubinstein, G. Locker. Cancer in Jews: introduction and overview. Familial Cancer., Not Applicable, 3(3-4), 177-192, 2004
  • Lynch, H.T., R.E. Brand, G.Y. Locker. Inflammatory bowel disease in Ashkenazi Jews: implications for familial colorectal cancer. Familial Cancer., Not Applicable, 3(3-4), 229-232, 2004
  • Lynch, H.T., C.A. Deters, J.F. Lynch, R.E. Brand. Familial pancreatic cancer in Jews. Familial Cancer., Not Applicable, 3(3-4), 233-240, 2004
  • Ghadirian,P., J. Lubinski, H. Lynch, S.L. Neuhausen, B. Weber, C. Isaacs, R-G. Baruch, S. Randall, P. Ainsworth, E. Freidman,D. Horsman, P. Tonin, W.D. Foulkes, N. Tung, P. Sun, S.A. Narod. Smoking and the risk of breast cancer among carriers of BRCA mutations., Int. J. Cancer, 110(3), 413-416, 2004
  • Lynch,H.T., J.N. Marcus, J.F. Lynch, C.L. Snyder, W.S. Rubinstein. Breast cancer genetics: heterogeneity, molecular genetics, syndrome diagnosis, and genetic counseling. The Breast: Comprehensive Management of Benign and Malignant Disorders, 3rd Edition. Bland,K.I., E.M. Copeland III (eds.), Saunders., Not Applicable, Vol. 1, 376-411, 2004
  • Attard,T.M., C. Cuffari, T. Tajouri, J.A. Stoner, M.T. Eisenberg, J.H. Yardley, S.C. Abraham, D. Perry, J. Vanderhoof, H. Lynch. Multicenter experience with upper gastrointestinal polyps in pediatric patients with familial adenomatous polyposis., Am J Gastroenterol, 99(4), 681-686, 2004
  • Lynch,H.T., J.F. Lynch. Hereditary nonpolyposis colorectal cancer (Lynch syndrome). Gastrointestinal and Liver Tumors. Scheppach,W., R.S. Bresalier, G.N.J. Tytgat (eds.), Springer-Verlag., Not Applicable, 142-159, 2004
  • Rebbeck,T.R., T. Friebel, H.T. Lynch, S.L. Neuhausen, L. van't Veer, J.E. Garber, G.R. Evans, S.A. Narod, C. Isaacs, E. Matloff, M.B. Daly, O.I. Olopade, B.L. Weber. Bilateral prophylactic mastectomy reduces breast cancer risk in BRCA1 and BRCA2 mutation carriers: the PROSE Study Group., J Clinical Oncology, 22(6), 1055-1062, 2004
  • Foulkes,W.D., K. Metcalfe, P. Sun, W.M. Hanna, H.T. Lynch, P. Ghadirian, N. Tung, O.I. Olopade, B.L. Weber, J. McLennan, I.A. Olivotto, L.R. Begin, S.A. Narod. Estrogen receptor status in BRCA1- and BRCA2-related breast cancer: the influence of age, grade, and histological type., Clin Cancer Res, 10(6), 2029-2034, 2004
  • Tinley,S., J. Houfek, P. Watson, L. Wenzel, M.B. Clark, S. Coughlin, H.T. Lynch. Screening adherence in BRCA1/2 families is associated with primary physicians' behavior., Am J Medical Genet, 125A(1), 5-11, 2004
  • Lynch,H.T., S.M. Coronel, R. Okimoto, H. Hampel, K. Sweet, J.F. Lynch, A. Barrows, J. Wijnen, H. van der Klift, P. Franken, A. Wagner, R. Fodde, A. de la Chapelle. A founder mutation of the MSH2 gene and hereditary nonpolyposis colorectal cancer in the United States., J.A.M.A., 291(6), 718-724, 2004
  • Lynch,H.T., S.T. Tinley, T.G. Shaw, J.F. Lynch, J.R. Howe, T.M. Attard. Challenging colonic polyposis pedigrees: differential diagnosis, surveillance, and management concerns., Cancer Genetics and Cytogenetics, 148(2), 104-117, 2004
  • Grushko,T.A., J.J. Dignam, S. Das, A.M. Blackwood, C.M. Perou, K.K. Ridderstråle, K.N. Anderson, M.O.J. Wei, A.J. Adams, F.G. Hagos, L. Sveen, H.T. Lynch, B.L. Weber, O.I. Olopade. MYC is amplified in BRCA1-associated breast cancers, Clin Cancer Res, 10(2), 499-507, 2004
  • Lynch,H.T., B.D. Riley, S. Weisman, S.M. Coronel, Y. Kinarsky, J.F. Lynch, T.G. Shaw, W.S. Rubinstein. Hereditary nonpolyposis colorectal carcinoma (HNPCC) and HNPCC-like families: problems in diagnosis, surveillance, and management., Cancer, 100(1), 53-64, 2004
  • Roland,I.H., W-L. Yang, D-H. Yang, M.B. Daly, R.F. Ozols, T.C. Hamilton, H.T. Lynch, A.K. Godwin, X-X. Xu. Loss of surface and cyst epithelial basement membranes and preneoplastic morphologic changes in prophylactic oophorectomies., Cancer, 98(12), 2607-2623, 2003
  • Lynch,H.T., J.F. Lynch, T.G. Shaw, J. Lubinski. HNPCC (Lynch syndrome): differential diagnosis, molecular genetics and management - a review. Hereditary Cancer in Clinical Practice, Not Applicable, 1(1), 7-18, 2003
  • Lynch,H.T., C.A. Deters, D. Hogg, J.F. Lynch, Y. Kinarsky, Z. Gatalica. Familial sarcoma/challenging pedigrees., Cancer, 98(9), 1947-1957, 2003
  • Loo,J.C., L. Liu, A. Hao, L. Gao, R. Agatep, M. Shennan, A. Summers, A.M. Goldstein, M.A. Tucker, C. Deters, R. Fusaro, K. Blazer, J. Weitzel,N. Lassam, H. Lynch, D. Hogg. Germline splicing mutations of CDKN2A predispose to melanoma., Oncogene, 22(41), 6387-6394, 2003
  • Brose,M.S., T.C. Smyrk, B. Weber, H.T. Lynch. Genetic predisposition to cancer. Cancer Medicine, 6th Edition. Kufe,D.W., R.E. Pollock, R.R. Weichselbaum, R.C. Bast, T.S. Gansler, J.F. Holland, E. Frei III (eds.), B.C. Decker., Not Applicable, Vol. 1, 241-265, 2003
  • Raevaara,T.E., C. Vaccaro, W.M. Abdel-Rahman, E. Mocetti, S. Bala, K.E. Lönnqvist, R. Kariola, H.T. Lynch, P. Peltomäki. Pathogenicity of the hereditary colorectal cancer mutation MLH1 del616 linked to shortage of the functional protein., Gastroenterology, 125(2), 501-509, 2003
  • Watson,P., S.A. Narod, R. Fodde, A. Wagner, J.F. Lynch, S.T. Tinley, C.L. Snyder, S.A. Coronel, B. Riley, Y. Kinarsky, H.T. Lynch. Carrier risk status changes resulting from mutation testing in hereditary nonpolyposis colorectal cancer and hereditary breast-ovarian cancer., J Med Genet, 40(8), 591-596, 2003
  • Glebov,O.K., L.M. Rodriguez, K. Nakahara, J. Jenkins, J. Cliatt, C-J. Humbyrd, J. DeNobile, P. Soballe, R. Simon, G. Wright, P. Lynch, S. Patterson, H. Lynch, S. Gallinger, A. Buchbinder, G. Gordon, E. Hawk, I.R. Kirsch. Distinguishing right from left colon by the pattern of gene expression., Cancer Epidemiol Biomarkers Prev, 12(8), 755-762, 2003
  • Ghadirian P, Lynch HT, Krewski D. Epidemiology of pancreatic cancer: an overview. Cancer Detection and Prevention., Not Applicable, 27, 87-93, 2003
  • Wagner A, Barrows A, Wijnen JT, van der Klift H, Franken PF, Verkuijlen P, Nakagawa H, Geugien M, Jaghmohan-Changur S, Breukel C, Meijers-Heijboer H, Morreau H, van Puijenbroek M, Burn J, Coronel S, Kinarski Y, Okimoto R, Watson P, Lynch JF, de la Chapelle A, Lynch HT, Fodde R. Molecular analysis of hereditary nonpolyposis colorectal cancer in the United States: High mutation detection rate among clinically selected families and characterization of an American founder genomic deletion of the MSH2 gene., American Journal of Human Genetics, 72, 1088 - 1100, 2003
  • Jaeger EEM, Woodford-Richens KL, Locket M, Rowan AJ, Sawyer EJ, Heinimann K, Rozen P, Murday VA, Whielaw SC, Ginsberg A, Atkin WS, Lynch HT, Southey MC, Debinski H, Eng C, Bodmer WF, Talbot IC, Hodgson SV, Thomas HJW, Tomlinson IPM. An ancestral Ashkenazi haplotype at the HMPS/CRAC1 locus on 15q13-q14 is associated with hereditary mixed polyposis syndrome., American Journal of Human Genetics, 72, 1261-1267, 2003
  • Lynch HT, de la Chapelle A. Genomic Medicine: Hereditary colorectal cancer. N Engl J Med., Not Applicable, 348, 919-932, 2003
  • Sarroca C, Peltomaki P, Alfano N, Tedesco G, Della Valle A, Dominguez A, Lynch HT. Three new mutations in hereditary nonpolyposis colorectal cancer (Lynch syndrome II) in Uruguay., Cancer Genetics and Cytogenetics, 142, 13-20, 2003
  • Lynch HT, Snyder CL, Lynch JF, Riley BD, Rubinstein WS. Hereditary breast-ovarian cancer at the bedside: role of the medical oncologist. J Clin Oncol., Not Applicable, 21, 740-753, 2003
  • Lynch HT, Deters CA, Lynch JF, Brand RA. Challenging pancreatic cancer-prone pedigrees: A nosologic dilemma., Am J Gastroenterol, 97, 3062-3070, 2002
  • Sayed MG, Ahmed AF, Ringold JR, Anderson ME, Bair JL, Mitros FA, Lynch HT, Tinley ST, Petersen GM, Giardiello FM, Vogelstein B, Howe JR. Germline SMAD4 or BMPR1A mutations and phenotype of juvenile polyposis., Annals of Surgical Oncology, 9, 901-906, 2002
  • Narod SA, Dube M-P, Klijn J, Lubinski J, Lynch HT, Ghadirian P, Provencher D, Heimdal K, Moller P, Robson M, Offit K, Isaacs C, Weber B, Friedman E, Gershoni-Baruch R, Rennert G, Pasini B, Wagner T, Daly M, Garber JE, Neuhausen SL, Ainsworth P, Olsson H, Evans G, Osborne M, Couch F, Foulkes WD, Warner E, Kim-Sing C, Olopade O, Tung N, Saal HM, Weitzel J, Merajver S, Gauthier-Villars M, Jernstrom H, Sun P, Brunet J-S. Oral contraceptives and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers., Journal of the National Cancer Institute, 94, 1773-1779, 2002
  • Wagner A, van der Klift H, Franken P, Wijnen J, Breukel C, Bezrookove V, Smits R, Kinarsky Y, Barrows A, Franklin B, Lynch J, Lynch H, Fodde R. A 10-Mb paracentric inversion of chromosome arm 2p inactivates MSH2 and is responsible for hereditary nonpolyposis colorectal cancer in a North-American kindred., Genes Chromosomes Cancer, 35, 49-57, 2002
  • Lynch HT, Lynch JF, Rubinstein WR. Prophylactic mastectomy: Obstacles and benefits (editorial). J Natl Cancer Inst., Not Applicable, 93, 1586-1587, 2002
  • Lynch HT, Weisenburger DD, Quinn-Laquer B, Watson P, Lynch JF, Sanger WG. Hereditary chronic lymphocytic leukemia: An extended family study and literature review., American Journal of Medical Genetics, 115, 113-117, 2002
  • Moriyama H, Sasamoto H, Kambara T, Matsubara N, Ikeda M, Baba S, Meltzer SJ, Lynch HT, Shimizu K, Tanada N. E2F-4 mutation in hereditary non-polyposis colorectal cancer., Journal of Experimental & Clinical Cancer Research, 21, 185-189, 2002
  • Lynch HT, Brand RE, Lynch JF, Fusaro RM, Kern SE. Hereditary factors in pancreatic cancer. J Hepatobiliary Pancreatic Surgical., Not Applicable, 9, 21-31, 2002
  • Lynch HT, Weisenburger DD, Quinn-Laquer B, Snyder CL, Lynch JF, Lipkin SM, Sanger WG. Family with acute myelocytic leukemia, breast, ovarian, and gastrointestinal cancer., Cancer Genetics and Cytogenetics, 137, 8-14, 2002
  • Cao Y, Pieretti M, Marshall J, Khattar NG, Chen B, Kam-Morgan L, Lynch H. Challenge in the differentiation between attenuated familial adenomatous polyposis and hereditary nonpolyposis colorectal cancer: case report with review of the literature., Am J Gastroenterol, 97, 1822-1827, 2002
  • Berry DA, Iversen ES, Gudbjartsson DF, Hiller EH, Garber JE, Peshkin BN, Parmigiani G. BRCAPRO validation, sensitivity of genetic testing of BRCA1/BRCA2, and prevalence of other breast cancer susceptibility genes., J Clinical Oncology, 20, 2701-2712, 2002
  • Park J-G, Vasen HFA, Park YJ, Park KJ, Peltomaki P, Ponzo de Leon M, Rodriguez-Bigas MA, Lubinski J, Beck NE, Bisgaard M-L, Miyaki M, Wijnen JT, Baba S, Lindblom A, Madlensky L, Lynch HT. Suspected HNPCC and Amsterdam criteria II: evaluation of mutation detection rate, an international collaborative study., Int J Colorectal Dis, 17, 109-114, 2002
  • Lynch HT, Lynch JF. Hereditary Cancer: Family history, diagnosis, molecular genetics, ecogenetics, and management strategies. Biochimie, Not Applicable, 84, 3-17, 2002
  • Rebbeck TR, Lynch HT, Neuhausen SL, Narod SA, van't Veer L, Garber JE, Evans G, Isaacs C, Daly MB, Matloff E, Olopade OI, Weber BL, for the Prevention and Observation of Surgical End Points Study Group. Prophylactic oophorectomy in carriers of BRCA1 or BRCA2 mutations., New England Journal of Medicine, 346, 1616-1622, 2002
  • Lynch HT, Brand RE, Hogg D, Deters CA, Fusaro RM, Lynch JF, Liu L, Knezetic J, Lassam NJ, Goggins M, Kern S. Phenotypic variation in eight extended CDKN2A germline mutation familial atypical multiple mole melanoma-pancreatic carcinoma-prone families: the familial atypical multiple mole melanomah-pancreatic carcinoma syndrome., Cancer, 94, 84-96, 2002
  • Lynch HT, Snyder CL, Riley BD, Lynch JF, Rubinstein WR. Hereditary breast cancer at the bedside. In: American Society of Clinical Oncology, editor. American Society of Clinical Oncology Educational Book: 38th Annual Meeting. Alexandria, Virginia: 2002, Not Applicable, 38th Annual Meeting, 1005-115, 2002
  • Prophylactic oophorectomy in carriers of BRCA1 or BRCA2 mutations. TR Rebbeck, HT Lynch, SL Neuhausen, SA Narod, L van't Veer, JE Garber, G Evans, C Isaacs, MB Daly, E Matloff, OI Olopade, BL Weber, for the Preventive and Observation of Surgical End Points Study Group., New England Journal of Medicine, 346, 1616-1622, 2002
  • HT Lynch, JF Lynch. ”Prophylactic Mastectomy: Obstacles and Benefits (editorial)., Journal of the National Cancer Institute, 93, 1586-1587, 2002
  • DA Berry, ES Iversen, DF Gudbjartsson, EH Hiller, JE Garber, BN Peshkin, C Lerman, P Watson, HT Lynch, SG Hilsenbeck, WS Rubinstein, KS Hughes, G Parmigiani. ”BRCAPRO Valination, Sensitivity of Genetic Testing of BRCA1/BRCA2, and Prevalence of other Breast Cancer Suseptibility Genes., J Clinical Oncology, 20, 2701-2712, 2002
  • J-G Park, HFA Vasen, YJ Park, KJ Park, P Peltomaki, M Ponzo de Leon, MA Rodriguez-Bigas, J Lubinski, NE Beck, M-L Bisgaard, M Miyaki, JT Wijnen, S Baba, A Lindbolm, L Madlensky, HT Lynch. ”Suspected HNPCC and Amsterdam criteria II: Evaluation of mutation detection rate, an international collaborative study, Int J Colorectal Dis, 17, 109-114, 2002
  • Hereditary Cancer: Family history, Dianosis, molecular genetics, ecogenetics, and management strategies. HT Lynch, JF Lynch., Biochimie, 84, 3-17, 2002
  • Hereditary factors in Pancreatic Cancer. HT Lynch, RE Brand, JF Lynch, FM Fusaro, SE Kern., J Hepatobiliary Pancreatic Surgery, 9, 21-31, 2002
  • Phenotypic variation in eight extended CDKN2A germline mutation familial atypical multiple mole melanoma-pancreatic carcinoma syndrome. HT Lynch, RE Brand, D Hogg, CA Deters, FM Fusaro, JF Lynch, L Liu, J Knezetic, NJ Lassam, M Goggins, S Kern., Cancer, 94, 84-96, 2002
  • Familial multiple myeloma: a family study and review of the liturature. HT Lynch, WG Sanger, S Pirruccello, B Quinn-Laquer, DD Weisenburger, Journal of the National Cancer Institute, 93, 1479-1483, 2001
  • Hereditary pancreatic cancer. HT Lynch, RE Brand, CA Deters, TG Shaw., Pancreatology, 1, 466-471, 2001
  • Cancer de mama hereditario: aspectos clinicos [Hereditary Breast Cancer: Clinical Aspects]. P Watson, H Lynch, Rev Senologia y Patol Mam, 14, 25-28, 2001
  • Family information service and hereditary cancer [commentary]. HT Lynch., Cancer, 91, 625-628, 2001
  • Smyrk TC, Watson P, Kaul K, Lynch, HT. Tumor-infiltrating lymphocytes are a marker for microsatellite instability in colorectal carcinoma. Cancer. 2001;91:2417-2422., Cancer, 91, 2417-2422, 2001
  • Rebbeck TR, Wang Y, Kantoff PW, Krithivas K, Neuhausen SL, Godwin AK, Daly MB, Narod SA, Brunet J-S, Vesprini D, Garber JE, Lynch HT, Weber BL, Brown M. Modification of BRCA1- and BRCA2-associated breast cancer risk by AIB1 genotype and reproductive history. Cancer Res 2001;61:5420-5424., Cancer Research, 61, 5420-5424, 2001
  • Lynch HT, Brand RE, Deters CA, Fusaro RM. Update on familial pancreatic cancer. Current Gastroenterology Reports. 2001;3:121-128., Current Gastroenterology, 3, 121-128, 2001
  • Tercyak KP, Hughes C, Main D, Snyder C, Lynch JF, Lynch HT, Lerman C. Parental communication of BRCA1/2 genetic test results to children. Patient Education and Counseling. 2001;42:213-224., Patient Education and Counseling, 42, 213-224, 2001
  • Watson P, Lynch HT. Cancer risk in mismatch repair gene mutation carriers. Familial Cancer 2001;1:57-60., Familial Cancer, 1, 57-60, 2001
  • Narod SA, Sun P, Ghadirian P, Lynch H, Isaacs C, Garber J, Weber B, Karlan B, Fishman D, Rosen B, Tung N, Neuhausen SL, Hereditary Ovarian Cancer Clinical Study Group. Tubal ligation and risk of ovarian cancer in carriers of BRCA1 or BRCA2 mutations: a case-control study. Lancet 2001;357:1467-1470., Lancet, 357, 1467-1470, 2001
  • Lynch H, Casey MJ. Current status of prophylactic surgery for hereditary breast and gynecologic cancers. Curr Opin Obstet Gynecol 2001;13:25-30., Cancer, 91, 625-628, 2001
  • Lynch H, Casey MJ. Current status of prophylactic surgery for hereditary breast and gynecologic cancers. Curr Opin Obstet Gynecol 2001;13:25-30., Current Opinion Obstetrics & Gynecology, 13, 25-30, 2001
  • de los Rios P, Jack E, Kuperstein G, Lynch H, Lubinski J, Narod SA. Foundation mutations of BRCA1 and BRCA2 in North American families of Polish origin that are affected with breast cancer [letter]. Am J Hum Genet 2001;68:546., American Journal of Human Genetics, 68, 546, 2001
  • Lynch HT, Brand RE, Lynch JF, Fusaro RM, Smyrk TC, Goggins M, Kern SE. Genetic counseling and testing for germline p16 mutations in two pancreatic cancer-prone families. Gastroenterology 2000;119:1756-1760., Gastroenterology, 119, 1756-1760, 2000
  • Liede A, Metcalfe K, Hanna D, Hoodfar E, Snyder C, Durham C, Lynch HT, Narod SA. Evaluation of the needs of male carriers of mutations in BRCA1 or BRCA2 who have undergone genetic counseling. Am J Hum Genet 2000;67:1494-1504., American Journal of Human Genetics, 67, 1494-1504, 2000
  • Lynch HT, Grady W, Lynch JF, Tsuchiya KD, Wiesner G, Markowitz SD. E-cadherin mutation-based genetic counseling and hereditary diffuse gastric carcinoma. Cancer Genet Cytogenet 2000;122:1-6., Cancer Genetics and Cytogenetics, 122, 1-6, 2000
  • Lynch HT, Lynch JF, Cristofaro G. The Lynch syndrome: historical perspective, molecular genetics, clinical manifestations, pathology surveillance and management. Osp Ital Chir 2000;6:531-536., Ospedali D'Italia Chirurgia, 6, 531-536, 2000
  • Lynch HT, Lynch JF. Hereditary nonpolyposis colorectal cancer syndromes (Lynch syndromes). In: Edelstein PS, ed. Colon and Rectal Cancer. New York: Wiley-Liss, Inc. 2000:67-93., Book, 67-93, 2000
  • Lynch HT, Fusaro RM. The dermatologist, genetic counseling, and cancer-associated genodermatoses [editorial]. J Am Acad Dermatol 2000;42:1081-1086., Journal of the American Academy of Dermatology, 42, 1081-1086, 2000
  • Narod SA, Brunet J-S, Ghadirian P, Robson M, Heimdal K, Neuhausen SL, Stoppa-Lyonnet D, Lerman C, Pasini B, de los Rios P, Weber B, Lynch H, for the Hereditary Breast Cancer Clinical Study Group. Tamoxifen and risk of contralateral breast cancer in BRCA1 and BRCA2 mutation carriers: a case-control study. Lancet 2000;356:1876-1881., Lancet, 356, 1876-1881, 2000
  • Brose MS, Smyrk T, Weber B, Lynch HT. Genetic predisposition to cancer. In: Bast RC, Kufe DW, Pollock RE, Weichselbaum RR, Holland JF, Frei E, eds. Cancer Medicine 5th ed. Hamilton, Ontario: B.C. Decker Inc.; 2000:168-184., Book, 168-184, 2000
  • Casey MJ, Bewtra C, Hoehne LL, Tatpati AD, Lynch HT, Watson P. Histology of prophylactically removed ovaries from BRCA1 and BRCA2 mutation carriers compared with noncarriers in hereditary breast ovarian cancer syndrome kindreds. Gynecol Oncol 2000;78:278-287., Gynecologic Oncology, 78, 278-287, 2000
  • Sarroca C, Alfano N, Bendin GT, Della Valle A, Dominguez C, Quadrelli R, Vaglio A, Mechoso B, Tinley ST, Harty AE, Lynch JF, Franklin BA, Kristo P, Smyrk TC, Peltomäki P, Lynch HT. Hereditary nonpolyposis colorectal cancer (Lynch syndrome II) in Uruguay. Dis Colon Rectum 2000;43:353-362., Diseases of the Colon & Rectum, 43, 353-362, 2000
  • Fusaro RM, Lynch HT. The FAMMM syndrome: epidemiology and surveillance strategies. Cancer Invest 2000;18:670-680., Cancer Investigation, 18, 670-680, 2000
  • Lynch HT. Anticipation in familial Hodgkin’s lymphoma (editorial). Hum Genet 2000;107:290-293., Human Genetics, 107, 290-293, 2000
  • Lynch HT, Lynch JF, Casey MJ, Bewtra C, Narod S. Genetics and gynecological cancer. In: Hoskins WJ, Perez CA, Young RC, eds. Principles and Practice of Gynecologic Oncology. 3rd ed. Philadelphia, PA: Lippincott-Raven Publishers; 2000:29-53., Book, 29-53, 2000
  • Lerman C, Hughes C, Croyle RT, Main D, Durham C, Snyder C, Bonney A, Lynch JF, Narod SA, Lynch HT. Prophylactic surgery decisions and surveillance practices one year following BRCA1/2 testing. Prev Med 2000;31:75-80., Preventive Medicine, 31, 75-80, 2000
  • Grady WM, Willis J, Guilford PJ, Dunbier AK, Toro TT, Lynch H, Wiesner G, Ferguson K, Eng C, Park J-G, Kim S-J, Markowitz S. Methylation of the CDH1 promoter as the second genetic hit in hereditary diffuse gastric cancer. Nat Genet 2000;26:16-17., Nature Genetics, 26, 16-17, 2000
  • Brand RE, Lynch MD. Hereditary pancreatic adenocarcinoma. Med Clin North Am 2000;84:665-675., Medical Clinics of North America, 84, 665-675, 2000
  • Lynch HT, McComb RD, Osborn NK, Wolpert PA, Lynch JF, Wszolek ZK, Sidransky D, Steg RE. Predominance of brain tumors in an extended Li-Fraumeni (SBLA) kindred, including a case of Sturge-Weber syndrome. Cancer 2000;88:433-439., Cancer, 88, 433-439, 2000
  • Lipkin SM, Wang V, Jacoby R, Banerjee-Basu S, Baxevanis AD, Lynch HT, Elliott RM, Collins FS. MLH3: a DNA mismatch repair gene associated with mammalian microsatellite instability. Nat Genet 2000;24:27-35., Nature Genetics, 24, 27-35, 2000
  • Yan H, Papadopoulos N, Marra G, Perrera C, Jiricny J, Boland CR, Lynch HT, Chadwick RB, de la Chapelle A, Berg K, Eshleman JR, Yuan W, Markowitz S, Laken SJ, Lengauer C, Kinzler KW, Vogelstein B. Conversion of diploidy to haploidy: individuals susceptible to multigene disorders may now be spotted more easily. Nature 2000;403:723-724., Nature, 403, 723-724, 2000
  • Lynch HT, Kaul K. Microsatellite instability, clinical implications, and new methodologies (editorial). J Natl Cancer Inst 2000;92:511-512., Journal of the National Cancer Institute, 92, 511-512, 2000
  • Lynch HT, Lynch JF. Genetics, natural history, and DNA-based genetic counseling in hereditary breast cancer. In: Winchester DJ, Winchester DP, eds. Breast Cancer: Atlas of Clinical Oncology. Hamilton, Ontario: B.C. Decker, Inc.; 2000:1-18., Book, 1-18, 2000
  • Lynch HT, Paulson J, Severin M, Lynch J, Lynch P. Failure to diagnose hereditary colorectal cancer and its medicolegal implications: a hereditary nonpolyposis colorectal cancer case. Dis Colon Rectum 42:31-35, 1999, Not Applicable, 1999
  • Lynch HT, Watson P, Tinley S, Snyder C, Durham C, Lynch J, Kirnarsky Y, Serova O, Lenoir G, Lerman C, Narod SA. An update on DNA-based BRCA1/BRCA2 genetic counseling in hereditary breast cancer. Cancer Genet Cytogenet 109:91-98, 1999, Not Applicable, 1999
  • Lynch HT, Leibowitz R, Smyrk T, Fusaro RM, Lynch JF, Smith A, Franklin B, Stella A, Liu B. Colorectal cancer and the Muir-Torre syndrome in a Gypsy family: a review. Am J Gastroenterol 94:575-580, 1999;, Not Applicable, 1999
  • Puget N, Sinilnikova OM, Stoppa-Lyonnet D, Audoynaud C, Pags S, Lynch HT, Goldgar D, Lenoir GM, Mazoyer S. An Alu-Mediated 6-kb duplication in the BRCA1 gene: a new founder mutation? Am J Hum Genet 64:300-302, 1999;, Not Applicable, 1999
  • Lerman C, Hughes C, Trock BJ, Myers RE, Main D, Bonney A, Abbaszadegan MR, Harty AE, Franklin BA, Lynch JF, Lynch HT. Genetic testing in families with hereditary nonpolyposis colon cancer. JAMA 281:1618-1622, 1999, Not Applicable, 1999
  • Rebbeck TR, Kantoff PW, Krithivas K, Neuhausen S, Blackwood MA, Godwin AK, Daly MB, Narod SA, Garber JE, Lynch HT, Weber BL, Brown M. Modification of BRCA1-associated breast cancer risk by the polymorphic androgen-receptor CAG repeat. Am J Hum Genet 64:1371-1377, 1999, Not Applicable, 1999
  • Hughes C, Lynch H, Durham C, Snyder C, Lemon S, Narod S, Fulmore C, Main D, Lerman C. Communication of BRCA1/2 test results in hereditary breast cancer families. Cancer Research Therapy and Control 8:51-59, 1999;, Not Applicable, 1999
  • Vasen HFA, Watson P, Mecklin J-P, Lynch HT, The ICG-HNPCC. New clinical criteria for hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome) proposed by the International Collaborative Group on HNPCC. Gastroenterology 116:1453-1456, 1999, Not Applicable, 1999
  • Ichikawa Y, Lemon SJ, Wang S, Franklin B, Watson P, Knezetic JA, Bewtra C, Lynch HT. Microsatellite instability and expression of MLH1 and MSH2 in normal and malignant endometrial and ovarian epithelium in hereditary nonpolyposis colorectal cancer family members. Cancer Genet Cytogenet 112:2-8, 1999, Not Applicable, 1999
  • Lin KM, Ternent CA, Adams DR, Thorson AG, Blatchford GJ, Christensen MA, Watson P, Lynch HT. Colorectal cancer in hereditary breast cancer kindreds. Dis Colon Rectum 42:1041-1045, 1999;, Not Applicable, 1999
  • Rebbeck TR, Levin AM, Eisen A, Snyder C, Watson P, Cannon-Albright L, Isaacs C, Olopade O, Garber JE, Godwin AK, Daly MB, Narod SA, Neuhausen SL, Lynch HT, Weber BL. Breast cancer risk after bilateral prophylactic oophorectomy in BRCA1 mutation carriers. J Natl Cancer Inst 91:1475-1479, 1999, Not Applicable, 1999
  • Guilford PJ, Hopkins JBW, Grady WM, Markowitz SD, Willis J, Lynch H, Rajput A, Wiesner GL, Lindor NM, Burgart LJ, Toro TT, Lee D, Limacher J-M, Shaw DW, Findlay, MPN, Reeve AE. E-cadherin germline mutations define an inherited cancer syndrome dominated by diffuse gastric cancer. Hum Mutat 14:249-255, 1999, Not Applicable, 1999
  • Park J-G, Vasen HFA, Park KJ, Peltomaki P, Ponz de Leon M, Rodriguez-Bigas MA, Lubinski J, Beck NE, Bisgaard M-L, Miyaki M, Wijnen JT, Baba S, Lynch HT. Suspected hereditary nonpolyposis colorectal cancer: International Collaborative Group on Hereditary Non-Polyposis Colorectal Cancer (ICG-HNPCC) criteria and results of genetic diagnosis. Dis Colon Rectum 42:710-715, 1999, Not Applicable, 1999
  • Shashidharan M, Smyrk T, Lin KM, Ternent CA, Thorson AG, Blatchford GJ, Christensen MA, Lynch HT. Histologic comparison of hereditary nonpolyposis colorectal cancer associated with MSH2 and MLH1 and colorectal cancer from the general population. Dis Colon Rectum 42:722-726, 1999;, Not Applicable, 1999
  • Shugart YY, Cour C, Renard H, Lenoir G, Goldgar D, Teare D, Easton D, Rahman N, Gusterton R, Seal S, Barfoot R, Stratton M, Mangion J, Peelen T, Van den Ouweland A, Meijers H, Devilee P, Eccles D, Lynch H, Weber B, Stoppa-Lyonnet D, Bignon Y-J. Linkage analysis of 56 multiplex families excludes the Cowden disease gene PTEN as a major contributor to familial breast cancer. J Med Genet 36:720-721, 1999., Not Applicable, 1999
  • Lynch HT, Lynch PM. Invited editorial [Re: Berk et al., Negative genetic test result in familial adenomatous polyposis]. Dis Colon Rectum 42:310-312, 1999, Not Applicable, 1999
  • Lynch HT, Watson P, Narod SA. The genetic epidemiology of male breast carcinoma (editorial). Cancer 86:744-746, 1999;, Not Applicable, 1999
  • Lynch HT. Hereditary nonpolyposis colorectal cancer (HNPCC). Cytogenet Cell Genet 86:130-135, 1999;, Not Applicable, 1999
  • Lynch HT, de la Chapelle A. Genetic susceptibility to non-polyposis colorectal cancer. J Med Genet 36:801-818, 1999, Not Applicable, 1999
  • Lynch HT, Lynch JF. Pros and cons of genetic screening for breast cancer [editorial]. American Family Physician 59:43-45, 1999;, Not Applicable, 1999
  • Lynch HT, Smyrk TC. Hereditary colorectal cancer. Semin Oncol 26:478-484, 1999;, Not Applicable, 1999
  • Lynch HT, Watson P, Shaw TG, Lynch JF, Harty AE, Franklin BA, Kapler CR, Tinley ST, Liu B. Clinical impact of molecular genetic diagnosis, genetic counseling, and management of hereditary cancer. Part I: Studies of cancer in families. Cancer 86:2449-2456, 1999;, Not Applicable, 1999
  • Lynch HT, Watson P, Shaw TG, Lynch JF, Harty AE, Franklin BA, Kapler CR, Tinley ST, Liu B, Lerman C. Clinical impact of molecular genetic diagnosis, genetic counseling, and management of hereditary cancer. Part II: Hereditary nonpolyposis colorectal carcinoma as a model. Cancer 86:2457-2463, 1999;, Not Applicable, 1999
  • Lynch HT, Fusaro RM. The Muir-Torre syndrome in kindreds with hereditary nonpolyposis colorectal cancer (Lynch syndrome): a classic obligation in preventive medicine. J Am Acad Dermatol 41:797-799, 1999, Not Applicable, 1999
  • Lynch HT. Environment and genes in the development of colorectal cancer (commentary). Ital J Gastroenterol Hepatol 31:223, 1999;, Not Applicable, 1999
  • Lynch HT, Lin K, Smyrk T, Watson P, Thorson A, Shashidharan M, Franklin B, Karr B, Lynch JF, Tinley S, Lanspa S, Lemon SJ, Shaw T, Rodriguez-Bigas MA. HNPCC: genetics, counseling, natural history, surveillance, and management. In: Utsunomiya J, Mulvihill JJ, Weber W (eds). Familial Cancer and Prevention. New York: Wiley-Liss, Inc. 1999, pp. 197-206;, Not Applicable, 1999
  • Lynch JF, Lemon SJ, Durham C, Snyder C, Lynch HT, Lerman C, Lenoir G, Serova O, Tonin P, Narod S. Hereditary breast cancer: DNA-based genetic counseling. In: Utsunomiya J, Mulvihill JJ, Weber W (eds). Familial Cancer and Prevention. New York: Wiley-Liss, Inc. 1999, pp. 441-446;, Not Applicable, 1999
  • Lynch HT, Lynch JF, Shaw TG, Smyrk TC. Genetics of colorectal cancer: an updated review. In: Shaw GL (ed). Cancer Genetics for the Clinician. New York: Kluwer Academic/Plenum Publishers. 1999, pp. 153-172., Not Applicable, 1999
  • Thorson AG, Knezetic JA, Lynch HT. A century of progress in hereditary nonpolyposis colorectal cancer (Lynch syndrome). Dis Colon Rectum 42:1-9, 1999;, Not Applicable, 1999
  • Boyd J, Rhei E, Federici MG, Borgen PI, Watson P, Franklin B, Karr B, Lynch J, Lemon SJ, Lynch HT. Male breast cancer in the hereditary nonpolyposis colorectal cancer syndrome. Breast Cancer Res Treat 53:87-91, 1999, Not Applicable, 1999
  • Smyrk TC, Lynch HT. Microsatellite instability: impact on cancer progression in proximal and distal colorectal cancers [editorial]. Eur J Cancer 35:171-172, 1999;, Not Applicable, 1999
  • Caldas C, Carneiro F, Lynch HT, Yokota J, Wiesner GL, Powell SM, Lewis FR, Huntsman DG, Pharoah PDP, Jankowski JA, MacLeod P, Vogelsang H, Keller G, Park KGM, Richards FM, Maher ER, Gayther SA, Oliveira C, Grehan N, Wight D, Seruca R, Roviello F, Ponder BAJ, Jackson CE. Familial gastric cancer: overview and guidelines for management. J Med Genet 36:873-880, 1999;, Not Applicable, 1999
  • Tinley ST, Lynch HT. Integration of family history and medical management of patients with hereditary cancers. Cancer 86:2525-2532, 1999, Not Applicable, 1999
  • Watson P, Lin K, Lynch HT, Rodriguez-Bigas MA. Colorectal cancer prognosis in hereditary nonpolyposis colorectal cancer. In: Utsunomiya J, Mulvihill JJ, Weber W (eds). Familial Cancer and Prevention. New York: Wiley-Liss, Inc. 1999, pp. 207-210., Not Applicable, 1999

Publications

  • Lynch HT, Narod SA, Fodde R, Wagner A, Lynch JF, Tinley ST, Snyder CL, Coronel S, Riley B, Kinarsky Y, Watson P. Mutation Risk Status Changes Resulting from Mutation Testing in HNPCC and HBOC. Thirty Ninth Annual Meeting, ASCO. Chicago, Illinois, American Society of Clinical Oncology, 2003

Editing and Reviews

  • Lynch HT, Lanspa SJ, Snyder CL, Drescher KM. Microsatellite instability, disease-free survival and role of tumour infiltrating lymphocytes (Invited Editorial on 'Predictors of disease-free survival in colorectal cancer with microsatellite instability: An AGEO multicenter study')., European Journal of Cancer, 51(8), 922-4, 2015
  • Lanspa SJ, Lynch HT. Sessile serrated adenomas: why conventional endoscopy is okay for unconventional polyps., Digestive Diseases and Sciences, 59, 2848-2849, 2014
  • Catalona WJ, D’Amico V, Fitzgibbons WF, Kosoko-Lasaki O, Leslie SW, Lynch HT, Moul JW, Rendell MS, Walsh PC. What the U.S. Preentive Services Task Force Missed in Its Prostate Cancer Screening Recommendation., Annals of Internal Medicine, EPub Ahead of Print, 2012
  • Lanspa SJ, Ahnen DJ, Lynch HT. Serrated polyposis: The last (or only the latest?) frontier of familial polyposis., Am J Gastroenterol, 107, 779-781, 2012
  • Lynch, HT, Lanspa, SJ. Colorectal Cancer Survival Advantage in MUTYH-Associated Polyposis and Lynch Syndrome Families., J Natl Cancer Inst, 22, 1371-1374, 2010
  • Lanspa SJ, Lynch HT. Quality Indicators for Colonoscopy and the Risk of Interval Cancer., New England Journal of Medicine, 363, 1371, 2010
  • Lynch HT, Casey MJ. Prophylactic surgery prevents endometrial and ovarian cancer in the Lynch syndrome., Nat Clin Pract Oncol, 4(12), 672-673, 2007
  • Lynch, H.T. Oncogenetics and interdisciplinary collaborations: essential for progress., Familial Cancer, 5(1), 1, 2006
  • Lynch, H.T. Introduction, Familial Cancer, 4(3), 209-210, 2005
  • Attard, T., H. Lynch. The genetics of FAP can be a nightmare., Arch Surg, 140(2), 164, 2005
  • Sweet,K.M., H.T. Lynch. Genetic aetiology of diffuse gastric cancer: so near, yet so far., J Med Genet, 41(7), 481-483, 2004
  • Roy,H.K., H.T. Lynch. Diagnosing Lynch syndrome: is the answer in the mouth?, Gut, 52(12), 1665-1667, 2003

General

Presentations

  • 12th Annual Esophageal Conference. Lecture entitled "Familial Aspects of BE & EAC - Should We Screen Families? held in Omaha, NE., 2015
  • Hereditary Cancer Symposium. Lecture entitled "Familial Malignant Multiple Mole Melanoma (FAMMM) Syndrome: CDKN2A/P-16 Mutation" with Ramon M. Fusaro, MD, MS, PhD, held in Omaha, NE., 2015
  • Presentation in Vancouver, BC, for CIQC/CAP-ACP Seminar in Diagnostic Immunohistochemistry, British Columbia Cancer Research Centre entitled" The History of Lynch syndrome.", 2015
  • Keynote speaker - Morristown Surgical Symposium, Morristown Medical Center. Lecture entitled: "Lynch syndrome: Its surgical implications." Also an informal lecture at the Morristown Surgical Society Dinner entitled "Familial Malignant Multiple Melanoma (FAMMM) Syndrome: CDKN2A (P-16) Mutation", 2015
  • Lecture/presentation at the Lynch Syndrome International (LSI) Conference in Orlando, Florida. Lecture/presentation entitled “The History of Lynch Syndrome” Lecture/presentation entitled “Gynecology Screening Options in Lynch Syndrome – Personalization Above and Beyond NCCN Guidelines” Closing Session – “The Future of Lynch Syndrome”, 2014
  • Grand Rounds Lecture/presentation first annual Colorectal Cancer Awareness event. Oncology Grand Rounds – Houston Methodist Research Institute, in Houston, Texas. Grand Rounds Lecture/presentation entitled “Lynch syndrome: hereditary cancer, past and present.”, 2014
  • Lecture/presentation at the Lynch Syndrome Southwest Campaign in Phoenix, Arizona. Lecture entitled: “Lynch syndrome: hereditary cancer, past and present.”, 2014
  • Lecture/presentation at the Biomarkers in Neoplasia academic event in Cali, Columbia. Lecture entitled: “Lynch syndrome: hereditary cancer, past and present.”, 2013
  • Kalamazoo, Michigan - Lynch Syndrome Conference for families and interested primary care providers. Bronson Gilmore Center for Health Education – Kalamazoo Special Presentation: Colon Cancer – Are you at risk? – Keynote speaker – lunch event at 12:30 – 1:30PM – Lecture on colon cancer for the public (lay persons) held at the Bronson Gilmore Center., 2013
  • Kalamazoo, Michigan - Lynch Syndrome Conference for families and interested primary care providers. Bronson Gilmore Center for Health Education – Kalamazoo Special Presentation: Keynote speaker – dinner event March 8 at 5:30PM – Lecture entitled “An Update of the Lynch Syndrome in the Quest for Reducing its Morbidity and Mortality” (Lecture to medical professionals)., 2013
  • Mountain View, California - CME presentation Title: “An update of the Lynch syndrome in the quest for reducing its morbidity and mortality” -El Camino Hospital., 2013
  • LLU Pathology and Human Anatomy conference, Loma Linda, California. Lecture entitled "Hereditary Breast Ovarian Cancer (HBOC): Prevention Implications” (Swatek lecturer)., 2013
  • LLU Pathology and Human Anatomy conference Loma Linda, CA - Banquet Speaker – “An Update of the Lynch Syndrome in the Quest for Reducing its Morbidity and Mortality”, 2013
  • One hour lecture at The University of Hawaii Cancer Center on February 20, 2013, 12:00pm entitled ““An update of the Lynch syndrome in the quest for reducing its morbidity and mortality”, 2013
  • Dayton, Ohio - Robinow lecture of 2012 Grand Rounds lecture related to Lynch syndrome Resident Teaching Rounds with a focus on hereditary breast cancer and Case Conference, 2012
  • Omaha, Nebraska - AVAHO 8th Annual Meeting Association of VA Hematology/Oncology Lecture Title: “Update on Lynch syndrome”, 2012
  • Providence, Rhode Island - Warren Alpert Medical School CME program Lecture Title: Colorectal Cancer – How is Genetics Transforming Clinical Practice Lecture Title: Colorectal Cancer: A Lifelong Conviction to Diagnosis, Surveillance, and Management, 2012
  • San Jose, California - Cancer Genetics Course (Myriad Genetics) Lecture Topic: An Update of the Lynch Syndrome: Genetic Counseling, Molecular Genetics and Clinical Aspects, 2012
  • Omaha, Nebraska - American Cancer Society lecuture to Colorectal Cancer Support Group. Lecture Title: Hereditary Colorectal Cancers, 2012
  • Accepted poster for an abstract at the 2012 ASCO Annual Meeting in Chicago, Illinois. Abstract entitled "Identification of new susceptibility genes in familial breast cancer by exome sequencing." Co-authored by Hongxiu Wen, Yeong C. Kim, Carrie Snyder, Yulia Kinarsky, Pei Xian Chen, Kenneth H. Cowan, David Goldgar, and San Ming Wang., 2012
  • FHCRC Genome Symposium, Seattle Washington, Keynote lecture entitled "Hereditary cancer models in the quest for genomics revolutionizing cancer therapy.", 2012
  • University of Chicago Cancer Genetics Conference, Chicago, IL, guest speaker, lecture entitled “Lynch Syndrome – what have we learned in the last 50 years?”, 2012
  • Lectures for Ambry Genetics, Los Angeles, CA – Two lectures entitled “Cancer Genetics: Identification and Management of Individuals with Lynch Syndrome.”, 2012
  • Grand Rounds for the Department of Internal Medicine at Mayo Clinic in Arizona, Scottsdale, Arizona, visiting speaker, lecture entitled “The Lynch syndrome: Natural history, molecular genetics and genetic counseling.”, 2012
  • Grand Rounds in Medicine Lankenau Hospital, Wynnewood, PA, Grand Rounds lecture entitled “Hereditary Breast Cancer: Differential Genetic Diagnosis.”, 2012
  • Genetic Risk Evaluation and Testing: An Advanced course for the Community Clinician (Myriad Genetics) – Las Vegas, NV, keynote address entitled “Hereditary Cancer Syndromes: Nuts and Bolts.”, 2012
  • Tumor Board Conference, Northside Hospital, Atlanta, Georgia, lecture entitled “Lynch Syndrome Testing and Genetic Aspects.”, 2011
  • Cancer Research Center Lunch lecture entitled “Cancer Genetics: Identification and Management of Individuals with Lynch Syndrome” and Hawaii Society of Clinical Oncology dinner lecture entitled “Cancer Genetics: Identification and Management of Individuals with Lynch Syndrome.” Honolulu, Hawaii, 2011
  • Grand Rounds at Tripler Army Medical Center, Honolulu, Hawaii, lecture entitled “Is Cancer in your DNA” and afterwards a Resident and Staff lecture “Cancer Genetics: Identification and Management of Individuals with Lynch Syndrome.”, 2011
  • GI Symposium, Overlook Medical Center –Summit, New Jersey, lecture entitled “Lynch Syndrome Testing and Genetic Aspects.”, 2011
  • Seventh Annual Pacific Northwest Excellence in Healthcare Conference, Portland, Oregon, featured speaker, lecture entitled “Endometrial carcinoma in the Lynch syndrome: Genetic epidemiology, diagnosis and management.”, 2011
  • Ninth Annual Esophageal Conference, Omaha, Nebraska, lecture entitled “Familial Aspects of Barrett’s Esophagus and Esophageal AdenoCa.”, 2011
  • Grand Rounds Saint Alphonsus Cancer Care Center Symposium, (Ambry Genetics) Boise, Idaho, lecture entitled “Cancer Genetics: Identification & Management of Individuals with Lynch Syndrome.”, 2011
  • US Oncology Genetics Training course for community oncologist, Chicago, IL, keynote speaker, lecture entitled “Hereditary Cancer Syndromes: Nuts and Bolts.”, 2011
  • 2nd Symposium on Hereditary Breast & Ovarian Cancer: Risks and Challenges, NYC, NY, keynote speaker, lecture entitled “Hereditary Breast and Ovarian Cancer Syndrome: History, Surveillance, Management, and Molecular Genetics.”, 2011
  • Ambry Genetics – Scottsdale Healthcare Shea Medical Center, Scottsdale, AZ, lecture entitled “Cancer Genetics: Identification and Management of Individuals With Lynch Syndrome.”, 2011
  • Cancer Genetics and Northern Plains AI – held in Omaha, Nebraska, lecture entitled “Lynch syndrome and the Navajo.”, 2011
  • North Carolina Oncology Association (NCOA) Membership Conference, held in Raleigh, NC, lecture entitled “Genetic Syndromes.”, 2011
  • Lynch, HT, Update of Lynch Syndrome and its Variability and Importance of Communication in Families. Mayo Clinic. Rochester, MN., 2011
  • Lynch, HT, Genetic Syndromes and Diagnosing Hereditary Colorectal Cancer. Early detection and prevention of gastrointestinal cancers: How screening can save lives. Beaumont Hospitals. Royal Oak, MI. June 17, 2011., 2011
  • Lynch, HT, Update of Lynch Syndrome: EPCAM and Future Molecular Genetic Developments. Cancer Research Symposium: Bridging Basic and Clincial Cancer Research. Omaha, NE., 2011
  • Lynch, HT, Update of Lynch Syndrome and its Phenotypic and Genotypic Heterogenity. Second Annual Cancer Genetics Symposium. De Kalb Medical Center, Atlanta, GA., 2011
  • Lynch, HT, Management of the High Risk Patient. The Second International Breast Health Education Program: A Multidisciplinary Approach to Breast Disease. Al Khobar, Saudi Arabia., 2011
  • Lynch, HT, The Story of Breast Cancer Genes. The Second International Breast Health Education Program: A Multidisciplinary Approach to Breast Disease. Al Khobar, Saudi Arabia., 2011
  • Lynch, HT, Hereditary Breast and Ovarian Cancer: History and Evolution. 21st Annual National Interdisciplinary Breast Center Conference. Las Vegas, NV., 2011
  • Lynch, HT, Genetics and Families: Focus on the Family. 21st Annual National Interdisciplinary Breast Center Conference. Las Vegas, NV., 2011
  • Lynch, HT, 2011 Gastrointestinal Cancer Symposium ASCO Keynote Lecture, San Francisco, CA, keynote lecture entitled “Influence of Microsatellite Instability on Management of Colon Cancer.”, 2011
  • Lynch, HT, Massachusetts General Hospital Breast Rounds, Boston, MA, lecture entitled “An Update of Hereditary Breast Ovarian Cancer Syndromes Characterize the Importance of BRCA1 and BRCA2 Testing for Breast Cancer,” November 16, 2010., 2010
  • Lynch, HT, Lankenau Hospital Grand Rounds, Philadelphia, PA, lecture entitled “An Update of Lynch Syndrome and its Phenotypic and Genotypic Heterogeneity.”, 2010
  • Lynch, HT, Fox Chase Cancer Center Distinguished Lecture Series, Philadelphia, PA, lecture entitled “An Update of Lynch Syndrome and its Phenotypic and Genotypic Heterogeneity.”, 2010
  • Lynch, HT, Ninth Annual Women’s Health in the 21st Century, Creighton University, Omaha, Nebraska, lecture entitled “Female Hereditary Cancer.”, 2010
  • Lynch, HT, XXVII National Congress of Oncology, Cancun Quintana Roo, Mexico, lecture entitled “An Update of Hereditary Breast Ovarian Cancer Syndrome Characterizing the Importance of BRCA1 and BRCA2 Testing for Diagnosis, Genetic Counseling and Management.”, 2010
  • Lynch, HT, XXVII National Congress of Oncology, Cancun Quintana Roo, Mexico, lecture entitled “New Advances in Hereditary Diffuse Gastric Carcinoma: Implications for Genetic Counseling and Prophylactic Total Gastrectomy in CDH1 Germline Mutation Carriers.”, 2010
  • Lynch, HT, XXVII National Congress of Oncology, Cancun Quintana Roo, Mexico, lecture entitled “An Update of the Lynch Syndrome Featuring its Genetics, Natural History, Heterogeneity, Screening and Management.”, 2010
  • Lynch, HT, 14th Annual Meeting Collaborative Group of the Americas on Inherited Colorectal Cancer, Dallas, Texas, lecture entitled “The Extra Intestinal Cancers of Lynch Syndrome.”, 2010
  • Lynch, HT, 6th International Physician’s workshop on Waldenström’s Macroglobulinemia, Venice, Italy, lecture entitled “Familial predisposition in plasma cell disorders.”, 2010
  • Lynch, HT, 8th Annual Esophageal Conference, Creighton University Medical Center, Omaha, Nebraska, lecture entitled “Familial Aspects of Barrett’s Esophagus and Esophageal Adenocarcinoma.”, 2010
  • Lynch, HT, International Society of Gastrointestinal Oncology, Philadelphia, PA, lecture entitled “Inherited Syndromes in Gastrointestinal Cancers.”, 2010
  • Lynch, HT, Regional C G A Meeting, Buenos Aires, Argentina, lecture entitled “Lynch Syndrome: Presentation, Prevention and Treatment.”, 2010
  • Lynch, HT, Regional C G A Meeting, Buenos Aires, Argentina, lecture entitled “Registries: What For and How They Work.”, 2010
  • “Phenotypic and genotypic update of Lynch syndrome.” American Association for Cancer Research 101st Annual Meeting. Washington, DC., 2010
  • “Counseling and spreading the word.” 20th Annual National Interdisciplinary Breast Center Conference. Las Vegas, Nevada., 2010
  • “The long and winding road of cancer genetics. How we got here and what I have learned along the way.” 20th Annual National Interdisciplinary Breast Center Conference. Las Vegas, Nevada., 2010
  • “Hereditary Diffuse Gastric Cancer and CDH1 mutation.” King Hussein Cancer Center. Amman, Jordan., 2009
  • “Genetic heterogeneity and hereditary breast and ovarian cancer syndrome.” 15th Annual Multidisciplinary Symposium on Breast Disease. University of Florida, Jacksonville, Cairo, Egypt., 2009
  • “Hereditary Cancer Syndromes: Including ovarian cancer.” Keynote speaker. Ovarian Cancer Research Fund. Lincoln, Nebraska., 2009
  • “Hereditary colorectal cancer syndromes: molecular genetics, heterogeneity, natural history and management.” Inaugural Edward S. Schneir MD Lecture in Gastroenterology. Summa Health System. Akron, Ohio. September 16, 2009., 2009
  • “Hereditary colorectal cancer syndromes: molecular genetics, heterogeneity, natural history and management.” Northeastern Ohio Society for Gastroendoscopy. Akron, Ohio., 2009
  • “Hereditary Breast Cancer. Meet the Professor.” Royal College of Physicians. Dublin, Ireland., 2009
  • “Cancer genetics and breast cancer. Cancer at a Crossroads. Dublin, Ireland., 2009
  • “Genetics of colorectal cancer: Hereditary aspects.” 10th Annual Perspectives in Colorectal Cancer. Chicago, Illinois., 2009
  • "Practical Aspects of Assessing MSI Status: What Tests to Order and How to Interpret Them" American Society of Clinical Oncology annual meeting held in Orlando, Florida., 2009
  • "Familial/Hereditary Gastric Cancer/Diffuse Gastric Cancer and Early Gastric Cancer - Management Options" 2009 Society of American Gastrointestinal and Endoscopic Surgeons Scientific Session and Post-graduate Courses held in Phoenix, Arizona., 2009
  • "Psychosocial Issues: What We Have Learned, How we Can Help" National Consortium of Breast Centers 19th Annual National Interdisciplinary Breast Center Conference held in Las Vegas, Nevada., 2009
  • "The Story of Breast Cancer Genes" 14th Annual Multidisciplinary Symposium on Breast Disease held at the University of Florida, College of Medicine, Jacksonville, Amelia Island, Florida., 2009
  • "Historical Perspectives and Challenges in Colorectal Cancer" 34th meeting of the Association of Quebec Hematologists and Oncologists held in Quebec, Canada., 2009
  • "Strategies for Identifying Hereditary Nonpolyposis Colon Cancer (Lynch Syndrome)" Colorectal Congress 2008 held at Kantonsspital St. Gallen, Switzerland., 2008
  • "An oral History of Lynch Syndrome" 2nd Annual Symposium on Hereditary Cancers: What Health Care Professionals Need to Know at the University of Pittsburg in Pittsburgh, Pennsylvania., 2008
  • "Colon Cancer Genetics" 3rd Annual Fall Midwest Thoracic and GI Oncology Conference held at the University of Nebraska Medical Center in Omaha, Nebraska., 2008
  • "Revisiting the Family Tree: The Role of Hereditary Risk Factors" University of Cincinnati 12th Annual breast Conference: Reclaiming Control: Life After Breast Cancer held in Cincinnati, Ohio., 2008
  • "Familial Aspects of Barrett's Esophagus and Esophageal Adenocarcinomas" 6th Annual Esophageal Conference held at Creighton University Medical Center, Omaha, Nebraska., 2008
  • "Present and Future in Hereditary Cancer" Update in Coloproctology and the Third South American Regional Meeting of Collaborative Group of Americas held in Santiago, Chili., 2008
  • "Hereditary Colorectal Cancer Syndromes" Updates in Coloproctology and the Third South American Regional Meeting of Collaborative Group of Americas held in Santiago, Chili., 2008
  • "Genetics of Colorectal Cancer: Hereditary Aspects" 9th Annual Perspectives in Colorectal Cancer World Congress on Gastrointestinal Cancer held in Miami, Florida., 2008
  • "Hereditary Colorectal Cancer Syndromes" Midwest Colon Cancer Symposium held at Evanston Northwestern University, Northbrook, Illinois., 2008
  • "Colon Cancer: Genetics and Prevention" 2nd Nebraska Radiological Society Symposium, held in Nebraska City, Nebraska., 2008
  • Lynch HT, Snyder C, Lynch, JF, et al. "FIS Impact upon BRCA Testng Uptake and Prophylactic Oophorectomy/Mastectomy Among HBOC Attendees." ASCO Annual Meeting, Chicago, Illinois, 2008
  • “Molecular Signature as Cancer Risk Predictor in Breast and Colorectal Cancer.” Molecular Medicine: Applying Current and Emerging Technologies Symposium. University of Florida, Jacksonville, Department of Pathology, Lake Buenna Vista, Florida, 2008
  • “Hereditary Cancer: Yesterday, Today and Tomorrow.” 18th Annual National Interdisciplinary Breast Cancer Conference, National Consortium of Breast Centers. Las Vegas, Nevada, 2008
  • “Differential diagnosis, genetic Counseling and Gene Testing for BRCA1-2 Mutations.” Legacy Health System. Portland, Oregon, 2007
  • “Hereditary Colorectal Cancer and Differential Diagnosis: An Update of Lynch Syndrome.”Legacy Health System. Portland, Oregon, 2007
  • “Revisiting Lynch Syndrome: Beyond Colorectal Cancer Risk.” 57th Annual Meeting American Society of Human Genetics. San Diego, California, 2007
  • "Thirty years of hereditary breast and ovarian cancer research." Second International Symposium on Hereditary Breast and Ovarian Cancer: BRCA: New Innovations in Research and Practice. Montreal, Quebec, Canada, 2007
  • “Role of Genetics in the Pathogenesis of Colorectal Cancer.” 6th International Colorectal Cancer Congress. Aventura, Florida, 2007
  • “Hereditary Diffuse Gastric Cancer: Natural History, Genetic Counseling and CDH1 Mutation Status.” Pathology Grand Rounds. University of Nebraska Medical Center, Omaha, Nebraska, 2007
  • "Genetic susceptibility in ovarian cancer.” The Aueosperg Symposium on the Etiology of Ovarian Cancer. Vancouver, B.C., Canada, 2007
  • “Colorectal Cancer Genetics and Risk Management.” Colorectal Cancer and Genetics. Florida Hospital Cancer Institute, Orlando, Florida, 2007
  • “Hereditary Diffuse Gastric Cancer: Natural History, Genetic Counseling and CDH1 Mutation Status.” Surgical Grand Rounds. Memorial Sloan-Kettering Cancer Center. New York City, New York, 2007
  • “Hereditary Diffuse Gastric Cancer: Natural History, Genetic Counseling and CDH1 Mutation Status.” Symposium on Upper Gastrointestional Malignancies. New York City, New York, 2007
  • “Barrett’s: Genetics and Familial Patterns.” 5th Annual Esophageal Conference. Omaha,Nebraska, 2007
  • Hereditary Breast Cancer: Phenotypic and Genotypic Heterogeneity, 2007
  • Colorectal Cancer: What are the Hereditary, Intrinsic and Environmental Risk Factors?, 2007
  • Effective, Affordable, and Acceptable Screening for Colorectal Cancer, 2007
  • Health Disparities in Colorectal Cancer Management, 2007
  • Hereditary Colon Cancer: Update on the Lynch Syndrome, 2007
  • The Lynch Syndrome, 2007
  • The Lynch Syndrome and Other Less Familiar Inherited Syndromes - Can We Identify them and Prevent the Cancer?, 2007
  • Hereditary Cancer Syndrome: Germline Mutations and their Clinical Translation, 2007
  • Management of High Risk Breast Cancer Patients, 2007
  • Hereditary Breast Cancer: Phenotype and Genotype Heterogeneity, 2007
  • Historical Perspective of the Lynch Syndrome, 2007
  • The Lynch Syndrome: 40 years of Clinical and Basic Research., 2006
  • Is Prophylactic Colectomy Ever Indicated in HNPCC?, 2006
  • Familial Gastric Cancer, 2006
  • Role of Genetics in the Pathogenesis of Colorectal Cancer., 2006
  • Hereditary Breast Cancer, 2006
  • Genetic Testing for Colon Cancer, 2006
  • Update in Cancer Genetics: Clinical Translation, 2006
  • The FAMMM Syndrome and Pancreatic Cancer, 2006
  • Hereditary Colorectal Cancer: Syndrome Recognition-Lifesaving Potential, 2006
  • "Whom to test for hereditary colorectal cancer syndromes." 2006 World Congress on Gastrointestinal Cancer; European Society for Medical Oncology, Barcelona, Spain., 2006
  • "Family information service (FIS) in a BRCA1 extended family." Abstract and poster presentation. Annual meeting of the American Society for Clinical Oncology, Atlanta, Georgia., 2006
  • "Update on the Lynch syndrome." Grand rounds, Missouri Baptist Medical Center, St. Louis, Missouri., 2006
  • "Hereditary Colorectal Cancer." 2nd Annual Cancer Update Conference: Gastrointestinal Cancer; Kansas Medical Education Foundation, Topeka, Kansas., 2006
  • "Hereditary breast cancer." 20th Annual Midwest Cancer Symposium. Rush-Copley Cancer Center, Oak Brook, Illinois., 2006
  • Hereditary colorectal cancer screening and prevention. Risk Specific Colorectal Cancer Screening and Prevention Seminar. Florida Hospital Cancer Institute, Orlando, Florida., 2006
  • Hereditary aspects of breast cancer: High-risk patients with genetic predisposition. Update on the Management of Breast Cancer, University of Nebraska Medical Center, Omaha, Nebraska., 2006
  • Lynch syndrome: Differential diagnosis, genotypic and phenotypic heterogeneity. 2nd National Meeting of Spanish Society of Medical Oncology Cooperative Groups. Madrid, Spain., 2006
  • Phenotypic and genotypic heterogeneity in the Lynch syndrome: Diagnostic, surveillance and management strategies for cancer patients. National Colon Cancer Symposium. Nanchang, China., 2006
  • Hereditary cancer syndromes. Visiting Professor: Grand Rounds, National University Hospital, Singapore, China., 2006
  • Hereditary colorectal and pancreatic cancer. Visiting Professor, Alexandra Hospital, Singapore, China., 2006
  • Hereditary breast cancer. Visiting Professor, Kandang Kerbau Hospital, Singapore, China., 2006
  • Hereditary cancer syndromes. Visiting Professor: Oncology Grand Rounds, National University Hospital, Singapore, China., 2006
  • Hereditary breast cancer syndromes. Visiting Professor, Tan Tock Seng Hospital, Singapore, China., 2006
  • Familial malignant melanoma. Visiting Professor, National Skin Center, Singapore, China., 2006
  • Update on hereditary breast and colorectal cancer syndromes. Visiting Professor, Mount Elizabeth Hospital, Singapore, China., 2006
  • Clinical, molecular, pathology update on Lynch syndrome (HNPCC). Grand Rounds. Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania., 2005
  • Clinical/genetic update of Lynch syndrome. Visiting Professor - Hem/Onc Grand Rounds. Beth Israel Deaconess Medical Center, Harvard University, Boston, Massachusetts., 2005
  • Hereditary breast cancer: Its phenotypic and genotypic heterogeneity. Medical Grand Rounds. Beth Israel Deaconess Medical Center, Harvard University, Boston, Massachusetts., 2005
  • Hereditary breast-ovarian cancer (HBOC) syndrome and Lynch syndrome. OB/Gyn Grand Rounds, University of Nebraska Medical Center, Omaha, Nebraska., 2005
  • Lynch syndrome and hereditary diffuse gastric cancer: Screening versus prophylactic surgery. 9th Annual Cy Young Cancer Symposium. Jane Phillips Medical Center, Bartlesville, Oklahoma., 2005
  • Role of genetics in the pathogenesis of colorectal cancer. Fourth International Colorectal Cancer Congress. Aventura, Florida., 2005
  • Hereditary breast-ovarian cancer (HBOC) syndrome: history, tumor complement, and management. XXXIII Meeting of the International Society for Oncodevelopmental Biology and Medicine. Rhodes, Greece., 2005
  • Lynch syndrome and hereditary diffuse gastric cancer as models for cancer education and prevention. XXXIII Meeting of the International Society for Oncodevelopmental Biology and Medicine. Rhodes, Greece., 2005
  • Hereditary and familial colon cancer: from theory to clinical practice. 2005 World Congress on Gastrointestinal Cancer, European Society for Medical Oncology, Barcelona, Spain., 2005
  • Discussion on family trees and counseling. 2005 World Congress on Gastrointestinal Cancer, European Society for Medical Oncology, Barcelona, Spain., 2005
  • The beginning of hereditary cancer syndromes. 9th International Meeting on the Psychosocial Aspects of Genetic Testing for Hereditary Cancer. Thomas Jefferson University, Kimmel Cancer Center, Philadelphia, Pennsylvania., 2005
  • Hereditary colorectal cancer. Noon Cancer Conference. Advocate Christ Medical Center, Oak Lawn, Illinois., 2005
  • Lynch syndrome: Why are physicians missing the cases (Keynote speaker)? Cancer Control Through Genetics: An Advanced Practical Approach. University of Chicago, Center for Clinical Cancer Genetics, Chicago, Illinois., 2005
  • The American founder mutation for Lynch syndrome: prevalence and cancer control implications. American Society of Clinical Oncology, Annual Meeting. Orlando, Florida., 2005
  • The doctor's point of view. Annual Meeting, The American Society of Colon and Rectal Surgeons. The Medico-legal Implications of Caring for Patients and Families with Hereditary Colorectal Cancer Syndromes (Symposium). Philadelphia, Pennsylvania., 2005
  • Lynch syndrome: limitations of molecular genetic testing, surveillance and management, and the problem of stigmatization. 96th Annual Meeting, American Association for Cancer Research. The Role of Tumor Biology in Cancer Health Disparities (Symposium). Anaheim, California., 2005
  • Lynch syndrome: heterogeneity, differential diagnosis, germline mutations, surveillance and management. Medical grand rounds. Providence St. Vincent Medical Center, Portland, Oregon., 2005
  • Hereditary breast cancer: genetics, genetic counseling, heterogeneity, cancer control. Lecture to residents and staff. Providence St. Vincent Medical Center, Portland, Oregon., 2005
  • HNPCC: differential diagnosis, molecular genetics, counseling, surveillance, and management. Colorectal Cancer Update 2005. Kansas University, Mt. Carmel Regional Cancer Center, Pittsburg, Kansas., 2005
  • Genetics and colorectal cancer. Colorectal Cancer Prediction, Detection, and Prevention Program. Florida Hospitals, Orlando, Florida., 2005
  • Research with the Native American population. Common Ground lecture for health science students. Sponsored by Office of Health Sciences Multicultural and Community Affairs, Creighton University, Omaha, Nebraska, 2005
  • Lynch syndrome: differential diagnosis, natural history, genetic counseling, and management. Fascinated with Genetics (Symposium). VU University Medical Center, Amsterdam, the Netherlands., 2005
  • Are we over- or under-emphasizing risk? 2005 Breast Cancer Challenge Conference. University of Arkansas for Medical Sciences, Ridgedale, Missouri., 2005
  • Hereditary factors in gastrointestinal cancer: diagnosis and management. Annual Clinical Cancer Conference. Curtis and Elizabeth Anderson Cancer Institute, Memorial Health University Medical Center, Savannah, Georgia., 2004
  • Lynch syndrome: insights from the past and future implications. Portals of Progress: Insights from the Past - Future Directions (Symposium). Florida Hospital Cancer Institute, Orlando, Florida, 2004
  • Molecular basis and clinical aspects of hereditary nonpolyposis colorectal cancer. Third International Colorectal Cancer Congress. Sponsored by Yale University School of Medicine, Aventura, Florida., 2004
  • Hereditary gastrointestinal cancers: surveillance, management, and molecular genetics of Lynch syndrome and diffuse gastric carcinoma (Distinguished Speaker). 17th Conference of Jacques Cartier Center; Oncologists: Achievements and Challenges. University of Montreal, Montreal, Quebec, Canada., 2004
  • Hereditary colorectal cancer. Internal medicine grand rounds. Baylor University Health Center, Dallas, Texas., 2004
  • Hereditary colorectal cancer. University of Texas Southwestern Medical Center, Dallas, Texas., 2004
  • The Lynch syndrome: phenotypic and genotypic heterogeneity, counseling, surveillance, and management (Keynote lecture and research award recipient). Fourth Annual Cancer Conference. Aultman Cancer Center-Northeastern Ohio Universities, Canton, Ohio., 2004
  • HNPCC: differential diagnosis, molecular genetics, counseling, surveillance, and management. Seventeenth Annual Cancer Symposium. Rural Eastern Kansas Area Health Education Center, Kansas University Medical Center, Pittsburg, Kansas., 2004
  • Hereditary pancreatic cancer: molecular genetics and heterogeneity. Seventeenth Annual Cancer Symposium. Rural Eastern Kansas Area Health Education Center, Kansas University Medical Center, Pittsburg, Kansas., 2004
  • Lynch syndrome (HNPCC): genetic counseling, surveillance, management, and molecular genetics. Faith Regional Health Services, Norfolk, Nebraska., 2004
  • Lynch,H.T. . American Society of Clinical Oncology Annual Meeting. New Orleans, Louisiana. "Lynch syndrome founder mutations in families of Navajo and German-American heritage", 2004
  • National Cancer Institute Center for Cancer Research, Bethesda MD: Grand Rounds, "Lynch Syndrome: Genetic Counseling, Surveillance, Management, and Molecular Genetics", 2004
  • Asuncion, Paraguay: XII Paraguayan Surgery Conference, "Cancer Related to Genetic Anomalies", 2004
  • Lynch, H.T. . XII Paraguayan Congress of Surgery. Ascuncion, Paraguay. "Extra-colonic manifestations of the familial adenomatous polyposis (FAP) syndrome", 2004
  • Asuncion, Paraguay: XII Paraguayan Surgery Conference, "Lynch Syndrome: Molecular Genetics, Genetic Counseling, Differential Diagnosis, Surveillance and Management", 2004
  • Physicians' Education Resource, Chicago IL: Current Trends in Colorectal Cancer, "Approach to Patients with Familial Colorectal Cancer Syndromes", 2004
  • Seoul National University College of Medicine, Seoul, Korea: The 13th Cancer Research Institute Cancer Symposium--Molecular Changes in Gastric Cancer and their Clinical Implications, "Genetic Counseling in Diffuse Gastric Cancer: Study of Two Remarkable Families", 2004
  • Omaha NE: NSRT District VII Radiation Oncology Education Event, "The Genetic Links to Breast Cancer", 2004
  • Nice, France: 7th International Symposium on Molecular Basis of Predictive Oncology Intervention Strategies, "Familial Genetic Predisposition", 2004
  • The Israel Center for Disease Control, Tel Aviv, Israel: "Recent Progress in Oncogenetics and the Contribution to Cancer Control", 2003
  • Tel Aviv Medical Center, Tel Aviv, Israel: Grand Rounds, "Recent Progress in Oncogenetics and the Contribution to Cancer Control", 2003
  • Rabin Medical Center, Petach, Israel: Grand Rounds, "Recent Progress in Oncogenetics and the Contribution to Cancer Control", 2003
  • St. Mark's Hospital, London (sponsor), in Athens, Greece: 1st Congress of the Hellenic Society of Digestive Surgery, "Colorectal Familial Cancer", 2003
  • Scripps Memorial Hospital, La Jolla CA: Grand Rounds, "Hereditary Colorectal Cancer Syndromes", 2003
  • Banner Health, Loveland CO: New Horizons in Cancer Care: 2003 Regional Oncology Conference, "Cancer Genetic Testing and Counseling", 2003
  • University of Nebraska Medical Center, Omaha NE: Pathology Grand Rounds, "Hereditary Colorectal Cancer", 2003
  • Physicians Education Resource, Palm Beach FL: 2nd International Congress on Colorectal Cancer, "Molecular Basis and Clinical Aspects of HNPCC", 2003
  • Northwestern University Feinberg School of Medicine, Northbrook IL: Preventive GI Oncology Conference, "Genetics of GI Malignancies", 2003
  • George Washington University Medical Center, Williamsburg VA: 10th International Conference on GI Oncology--Hepatobiliary and Pancreatic Cancer, "Hereditary Pancreatic Cancer-prone Syndromes", 2003
  • Chicago IL: American College of Surgeons 89th Annual Clinical Congress, "Polyposis Syndromes: Nomenclature, Diagnosis, Timing of Intervention", 2003
  • University of Vermont Cancer Center, Burlington VT: 18th Regional Cancer Research Symposium, "HNPCC: Differentiated Diagnosis, Screening, Surgical Management, Genetic Counseling and Molecular Genetic Testing", 2003
  • Queen's University of Belfast, Belfast, Ireland: Second Annual New Horizons in Cancer Research Symposium, "Hereditary Colorectal Cancer Syndromes: Phenotypic and Genotypic Heterogeneity", 2003
  • Providence Hospital and Medical Center, Southfield MI: Ninth Annual Jaffer Oncology Conference--Strategies for Prevention and a Cure of Colon/Rectal Cancers, "Genetics and Colorectal Adenomas", 2003
  • St. Luke's Hospital, Kansas City MO: Oncology Speaker Series, "Hereditary Colorectal Cancer", 2003
  • University of Iowa Gastrointestinal Cancer Symposium, Iowa City IA: "Hereditary Colorectal Cancer Syndromes", 2003
  • Mayo Clinic Cancer Center, Rochester MN: Grand Rounds, "Genetics, Differential Diagnosis, Screening and Management of HNPCC", 2003
  • Ludwig Institute for Cancer Research, Sao Paulo, Brazil; "HNPCC: Differential Diagnosis, Molecular Genetics, Surveillance and Management, 2003
  • MD Anderson Cancer Center, Orlando, Florida: "Hereditary Colorectal Cancer Syndromes", 2003
  • Hereditary colon cancer. 20th International Academy of Tumor Marker Oncology. Siena, Italy., 2003
  • Clinical and molecular genetics in colorectal cancer syndromes. European Society for Medical Oncology Summer Educational Conference. Edinburgh, Scotland., 2003
  • Hereditary cancer syndromes: Lynch syndromes and gastrointestinal cancer. Annual Symposium - Innovations in Diagnosis, Staging and Management of Gastrointestinal Malignancies. Lurie Cancer Center, Northwestern University. Chicago, Illinois., 2003
  • A life of familial cancer: The long view. UICC International Conference Family Cancer: Biology and Clinical Care. Oklahoma City, Oklahoma., 2003
  • Mutation Risk Status Changes Resulting From Mutation Testing in HNPCC and HBOC. Thirty Ninth Annual Meeting, ASCO (American Society of Clinical Oncology). Chicago, Illinois (Poster/Abstract), 2003
  • Risk factors determining diagnostics and therapy in gastrointestinal oncology. Premalignant and Early Neoplastic Gastrointestinal Lesions Seminar. Technical University. Munich, Germany., 2003
  • Hereditary colorectal cancer: Differential diagnosis, surveillance and management of HNPCC. Hereditary Cancer: Recognition, Intervention and Prevention Symposium. Vanderbuilt University, Nashville, Tennessee., 2003
  • HNPCC: HIstory and current status. Diagnostic Guidelines for Hereditary Non-Polyposis Colorectal Cancer and Microsatellite Instability Conference. National Cancer Institute. Bethesda, Maryland., 2002
  • Molecular basis and clinical aspects of HNPCC. First International Colorectal Cancer Congress. Yale University. Palm Beach, Florida, 2002
  • Hereditary colorectal cancer syndromes. Cancer Genetic Risk Assessment and Cancer Prevention Program. Virginia G. Piper Cancer Center. Scottsdale, Arizona., 2002
  • Familial hematologic cancers. Lymphoma Study Group/Leukemia Network 2002 Fall Meeting. University of Nebraska Medical Center. Omaha, Nebraska., 2002
  • Hereditary colorectal cancer syndrome. The Changing Spectrum of Jewish Genetic Disorders: From Tay-Sachs to Breast Cancer Symposium. Feinburg School of Medicine, Northwestern University. Chicago, Illinois., 2002
  • Genetics of pancreatic cancer. Fifth Annual Meeting of the Association of Physician Assistants in Oncology. University of Nebraska Medical Center. Omaha, Nebraska, 2002
  • Genetics of colon cancer and polyposis. American College of Gastroenterology - Regional Symposium. University of Nebraska Medical Center. Omaha, Nebraska, 2002
  • Genetic evaluation of family members of cancer patients. Annual Alegent Health Oncology Update for Primary Care Physicians. Omaha, Nebraska, 2002
  • Hereditary colorectal cancer syndromes: Seminar introduction to cancer genetics. Norton Healthcare. Louisville, Kentucky, 2002
  • Grand Rounds "Hereditary/Familial Hematologic Malignancies" Sponsored by University of Nebraska Medical Center Omaha Nebraska, 2002
  • Annual Clinical Science Symposium "Hereditary Cancer Syndromes: Lynch Syndromes and Gastrointestional Cancers". Sponsored by Northwestern University Lurie Comprehensive Cancer Center. Chicago, Illinois, 2002
  • Annual Dameshek Symposium "Evaluation of Heritable Cancer Syndromes". Sponsored by: Via Christi Regional Medical Center. Wichita, Kansas, 2002
  • "Overview of Hereditary Colon Cancer" Sponsored by Fox Chase Cancer Center. Philadelphia, PA, 2002
  • "HNPCC: Differential Diagnosis, Molecular Genetics and Management". Sponsored by: Hereditary Cancer Center, Pomeranian Academy of Medicine. University of Szczecin Szczecin, Poland Held in Miedzyzdroje, Poland, 2002
  • Annual Meeting American Society of Clinical Oncology. "Cancer Genetics at the Bedside: Managing Aspects of Hereditary Cancers." Orlando, Florida, 2002
  • 63rd Annual Theador Lang May Day Symposium. "Genetics of Colorectal Cancer" Sponsored by St. Anthony Medical Center. Rockport, IL, 2002
  • Hereditary Gastric Cancer Symposium "Hereditary Gastric Cancer: Phenotypic and Genotypic Heterogeneity." Sponsored by the University of Porto. Porto, Portugal, 2002
  • Annual Oncology Symposium "Update on Hereditary Colorectal Cancer: Molecular Genetics, Surveillance, Management and Genetic Counseling." Sponsored by St. Mary's Medical Center Evansville, IN, 2002
  • National Advisory Board Symposium "Cancer Prevention and Genetics" Sponsored by Florida Hospital Cancer Institute. Orlando, Florida, 2002
  • 6th Annual Conference on Cancer Genetics. "An Update on Hereditary Pancreatic Cancer" Sponsored by City of Hope Comprehensive Cancer Center. Duarate, CA, 2002
  • Grand Rounds "The Genetics, Molecular Genetics and Natural History of HNPCC; and the FAMMM". Department of Pathology and Department of Microbiology. University of Nebraska Medical Center. Omaha, NE, 2002
  • Creighton University Neurology Grand Rounds. "Hereditary/Familial Brain Tumors" Omaha, NE, 2001
  • Midwest Pancreatic Cancer Network "Hereditary Pancreatic Cancer" Sponsored by University of Nebraska, Medical Center. Omaha, NE, 2001
  • Hereditary Cancer Risk Assessment: A Program for Healthcare Professionals. "Current understanding of HNPCC and Gastric Cancer (mismatch - repair genes and E-Cadherin)" Sponsored by Kimmel Cancer Center, Thomas Jefferson University. Philadelphia, PA, 2001
  • Grand Rounds. "Genetic Testing and Counseling for Hereditary Colon Cancer" Sponsored by Central DuPage Hospital. Winfield, IL, 2001
  • 24th Taubman Symposium "Hereditary Colorectal Cancer Syndromes"; "Hereditary Pancreatic Cancer and the FAMMM". Sponsored by St. John Medical Center Tulsa, OK, 2001
  • "Hereditary Breast Cancer: Genetic Counseling, Family Education, Surveillance and Management Options". Sponsored by the Tumor League of Rome International Forum on the Prevention of Tumors. Rome, Italy, 2001
  • "Prevention of Colon Cancer". "Hereditary Colorectal Cancer". 12th Annual Oncology Symposium, Colorectal Cancer. Union Hospital, Terre Haute, Indiana, 2001
  • "The History of HNPCC". 5th Annual meeting Collaborative Group of the Americas on Inherited Colorectal Cancer. Sponsored by University of Texas, M.D. Anderson Cancer Center. Held in San Diego, CA, 2001
  • The Don Wilson Symposium: Cancer of the Pancreas: "Risk Factors for Pancreatic Cancer: Practical Applications". 14th International Course on Therapeutic Endoscopy. University of Toronto, Toronto, Ontario, Canada., 2001
  • 6th Annual Cancer Conference "Hereditary Breast Cancer: Counseling, Genetic testing, Screening and Management". Missouri Baptist Medical Center, St. Louis, MO., 2001
  • Breast Cancer Summit 2001 "Clinical IMplications of Genetic Advances in Breast Cancer". University of Washington, Seattle WA., 2001
  • Hereditary Cancers: Identification and Management of High Risk Families "Colon Cancer Syndrome". University of Kansas, held in Kansas City, MO, 2001
  • Hereditary Nonpolyposis Colorectal Cancer (Lynch Syndrome). American Association for Cancer Research International Conference. Seoul, Korea, 2001
  • HNPCC: Historical and Clinical Aspect. IBID., 2001
  • Controversies in Identification, Genetic Testing, Surveillance/Management, and Genetic Counseling in Hereditary Colorectal Cancer (panel discussion). IBID, 2001
  • Genetics and Cancer (Inaugural Lecture). Latin American Coloproctology Conference and the XXVII National Surgical Advancements Conference. Bogota, Columbia, 2001
  • Hereditary Nonpolyposis Colorectal Cancer Syndrome. University of New Mexico Health Sciences Center Special Lecture. Albuquerque, New Mexico., 2001
  • Familial Atypical Multiple Mole Melanoma-Pancreatic Cancer Syndrome: Family Studies. Norton Hospital Tumor Board, Louisville, KY, 2001
  • Lynch HT. Hereditary breast cancer; primary prevention strategies for breast cancer. International Symposium on Breast Cancer. International Symposium on Breast Cancer. Sao Paolo, Brazil. June 29-30,2001., 2001
  • Lynch HT. Genotypic/phenotypic heterogeneity in 8 CDKN2A mutation positive pancreatic cancer-FAMMM families (Abstract #201067-oral presentation). 37th Annual Meeting, American Society of Clinical Oncology. San Francisco, California. May 12-15, 2001., 2001
  • Lynch HT. The role of genetics in breast cancer. William J. Smith Memorial Conference. Sponsored by the Mountain Area Health Education Center and the Mission St. Joseph’s Cancer Services. Asheville, North Carolina. April 27, 2001., 2001
  • Lynch HT. Hereditary breast and ovarian cancer. 14th Annual National Cancer Symposium. Sponsored by Rush-Copley Cancer Center. Chicago, Illinois. April 20-21, 2001., 2001
  • Lynch HT. Hereditary pancreatic cancer kindreds: a historical perspective and epidemiologic updates. Third International Symposium on Inherited Diseases of the Pancreas. Sponsored by the European Institute of Oncology and the University of Pittsburg. Held in Milan, Italy. April 5-7, 2001., 2001
  • Lynch HT. Hereditary colorectal cancer and pancreatic syndromes. Medical Grand Rounds, Tripler Medical Center. Honolulu, Hawaii. February 28, 2001., 2001
  • Lynch HT. Hereditary G.I. Cancer: Pancreatic cancer and HNPCC. Discovery to Practice Conference. Queen’s Medical Center. Honolulu, Hawaii. March 1, 2001, 2001
  • Lynch HT. Hereditary colon cancer: New molecular genetic findings. Advances in the Diagnosis and Treatment of Cancer Symposium. Sponsored by the Southern Illinois University Cancer Institute. Springfield, Illinois. February 22, 2001., 2001
  • Lynch HT. Hereditary breast cancer. 6th Annual Multidisciplinary Symposium on Breast Disease. Sponsored by the University of Florida, Amelia Island, FL. February 15-18, 2001., 2001
  • Lynch HT. Clinical aspects of other common hereditary cancer syndromes. National Symposium on Hereditary Cancer. Valencia, Spain. February 9, 2001., 2001
  • Lynch HT. Hereditary G.I. Cancers. 11th International Congress on Anticancer Treatment-Innovations in G.I. Oncology. Paris, France. February 7-8, 2001., 2001
  • Lynch HT. Genetics of cancer. Department of Medicine Grand Rounds, Lankenau Hospital. Wynnewood, Pennsylvania. February 2, 2001., 2001
  • 349. Lynch HT. Genetic testing and hereditary carcinomas. Healthy Siouxland 2001 Conference. Siouxland Regional Cancer Center. Sioux City, Iowa. January 31, 2001., 2001
  • 348. Lynch HT. Hereditary factors in pancreatic cancer and the FAMMM syndrome. University of Arizona Cancer Center. Tucson, Arizona. January 12, 2001., 2001
  • Lynch HT. Heredity and genetic issues in colon cancer. The Chicago Society for Gastroenterology. Chicago, Illinois. January 10, 2001., 2001
  • Lynch HT. Genetic investigation of Lynch I and Lynch II. IV International Symposium: Sphincter Saving Surgery for Rectal Cancer. Sponsored by the Italian National Cancer Institute. Milan, Italy. November 30 - December 2, 2000., 2000
  • Lynch HT. The evolution of HNPCC (Lynch syndrome) and its clinical impact. Gastrointestinal Research Conference 2000. Sponsored by University of Texas M.D. Anderson Cancer Center. Held in Orlando, FL. November 16-18, 2000., 2000
  • Lynch HT. Hereditary colorectal cancer syndromes. Riverside Medical Center. Kankakee, Illinois. November 8, 2000., 2000
  • Lynch HT. Hereditary nonpolyposis colorectal carcinoma. Puerto Rico Gastroenterology Association Sifre Conference. San Juan, Puerto Rico. October 29, 2000., 2000
  • Lynch HT. Hereditary breast cancer and colon cancer syndromes. University of Miami Jackson Memorial Hospital Familial Ovarian/Breast Cancer Center. Miami, Florida. October 18, 2000., 2000
  • Lynch HT. Molecular and genetic diagnosis of hereditary G.I. cancer: Screening and prevention of colon cancer. 5th Annual Cancer Conference. Missouri Baptist Medical Center. St. Louis, Missouri. October 6, 2000., 2000
  • Lynch HT. Management of patients from hereditary colorectal cancer kindreds. Seventh Annual International Conference on Gastrointestinal Oncology. Aracheon, France. September 28, 2000., 2000
  • Lynch HT. Hereditary colorectal cancer: Lynch syndrome as a model. Joint Meeting of Colon and Rectal Surgery and the Mediterranean Society of Coloproctology. Nazareth, Israel. September 24, 2000., 2000
  • Lynch HT. Family history and genetic testing. Ninth Annual Oncology Update For Primary Care: G.I. Malignancies. Sponsored by Alegent Health. Omaha, Nebraska. September 15, 2000, 2000
  • Lynch HT. Family history and genetic testing. Ninth Annual Oncology Update For Primary Care: G.I. Malignancies. Sponsored by Alegent Health. Omaha, Nebraska. September 15, 2000, 2000
  • Lynch HT. The Future of Cancer Research in Light of the Recent Genome Project. Golden K. Kiwanis Club. Omaha, Nebraska. September 5, 2000., 2000
  • Lynch HT. Familial/hereditary cancers: Genetics, natural history, genetic counseling and surveillance and management options. Norton Healthcare Cancer Center. Louisville, Kentucky. August 25, 2000., 2000
  • Lynch HT. Clinical, molecular, natural history and genetic counseling aspects in hereditary pancreatic cancer: Translational impact. 8th SPORE Investigator’s Workshop. Chantilly, Virginia. July 9-11,2000., 2000
  • Lynch HT. Familial pancreatic cancer syndromes. Pancreatic Cancer Think Tank. Sponsored by the National Cancer Institute, Organ Systems Branch. Held in Park City UT. September 16-19, 1999 (lecture delivered September 18, 1999)., 1999
  • Lynch HT. William C. Bernstein, M.D., Memorial Lecture: Clinical aspects of hereditary colorectal cancer. Colon and Rectal Surgery: Principles and Practice. University of Minnesota Medical School, Minneapolis MN. September 16-18, 1999 (lecture delivered September 17, 1999)., 1999
  • Lynch HT. Common hereditary cancer syndromes. Cancer Care Challenges in the New Millennium. Walt Disney Memorial Cancer Institute and Duke Comprehensive Cancer Center, Orlando, FL. September 10, 1999., 1999
  • Lynch HT. Familial lymphoma research. 1999 Pan-Pacific Lymphoma Conference. Sponsored by The University of Nebraska Medical Center, Omaha, NE, and The Queen's Medical Center Cancer Institute, Honolulu, HI. Held in Kauai, HI. July 20-23, 1999., 1999
  • Two presentations: 1) Hereditary and familial cancer; 2) Lynch syndrome I and II. XIV Argentine Congress of Oncology. Argentine Association of Clinical Oncology. Buenos Aires, Argentina. June 24-27, 1999., 1999
  • Lynch HT. HNPCC: update on molecular genetics, natural history, surveillance, and management (abstract and presentation). 16th International Conference on Human Tumor Markers. International Association of Tumor Marker Oncology. Budapest, Hungary. June 13-16, 1999., 1999
  • Lynch HT. Gastric cancer in HNPCC kindred. International Familial Gastric Cancer Workshop. University of Cambridge, Department of Oncology. Cambridge, England. June 4-5, 1999., 1999
  • Lynch HT. HNPCC: molecular genetics, differential diagnosis, genetic counseling and management. 35th Annual Meeting of the American Society of Clinical Oncology, Education Session on Molecular Genetic Diagnosis for Hereditary Cancer. Atlanta, GA. May 15-18, 1999., 1999
  • Lynch HT. National issues for genetic testing and counseling. Innovations in GI Cancer Control and Management: Genetics and Pancreatic Cancer. University of Pittsburgh, Pittsburgh, PA. May 3, 1999.;, 1999
  • Lynch HT. Familial breast and ovarian cancers. 1st Annual Oncology Symposium on Cancer Genetics. Kansas University, Mt. Carmel Regional Cancer Center. Pittsburg, KS. April 24, 1999., 1999
  • Lynch HT. Epidemiology of colorectal cancer. Current Concepts in the Management of Colorectal Cancer Symposium. University of Pennsylvania, Philadelphia, PA. April 16, 1999.;, 1999
  • Lynch HT. Colorectal cancer genetics. Berkshire Medical Center Annual Cancer Symposium. Pittsfield, MA. April 9, 1999;, 1999
  • Lynch HT. Clinical and molecular clues to hereditary cancer syndrome diagnosis. 1999 American Society of Clinical Oncology, Train the Trainer Update. New Orleans, LA. March 19, 1999., 1999
  • Lynch HT. Genetic counseling in HNPCC. 2nd Joint Meeting, Leeds Castle Polyposis Group and International Collaborative Group for Hereditary Nonpolyposis Colorectal Cancer. Lorne, Australia. March 1-6, 1999., 1999
  • Lynch HT. Genetics of colon cancer. 1999 Midwest Clinical Conference, Chicago Medical Society. Chicago, IL. February 26, 1999, 1999
  • Lynch HT. An overview of genetic predisposition. First Annual International Conference for Ovarian Cancer. University of Texas M.D. Anderson Cancer Center. Houston, TX. February 3-5, 1999, 1999

Awards and Honors

  • Recipient of the Women’s Cancer Innovation Award, SGO 45th Annual Meeting on Women’s Cancer in Tampa, Florida, 2014
  • 2010 AACR Joseph H. Burchenal Memorial Award for Clinical Research, 2010
  • Intramural Research Award, Nebraska Oncology Society, 2009
  • Awarded the annual IMPACT award, The National Consortium of Breast Centers in Las Vegas, Nevada, 2009
  • Honor Member of SEOM and Cancer Heritage SEOM Section, Spanish Society of Medical Oncology, 2006
  • Lifetime Achievement Award in Inherited Pancreatic Diseases, The International Association of Pancreatology, 2001
  • Carlos Canter Award for G.I. Cancer Research, M.D. Anderson Cancer Center, 2000
  • Intramural Research Award, Creighton University School of Medicine, November 9, 1999, 1999