Yaping Tu, PhD

Yaping Tu, PhD

Yaping Tu, PhD

Professor
School of Medicine, Omaha Campus

Academic Appointments

Department

  • Pharmacology and Neuroscience

Position

  • Professor

Biography


Cancer Research Focus

The long-term objective of Dr. Tu’s research is to develop new therapies for castration-resistant prostate cancer and drug-resistant colorectal cancer. Current research projects are focused on the pivotal role and mechanisms of signal transduction dysregulation in cancer development and progression using various cellular, tissue and murine models.
  • Breast Cancer
  • Colon Cancer
  • Prostate Cancer
Asthma Research Focus
 
Asthma is a chronic obstructive inflammatory airway disease with substantial morbidity and mortality that affects over 300 million people worldwide. Airway hyperresponsiveness and airway inflammation are hallmarks of asthma clinically managed with β2-agonist bronchodilators and corticosteroids. Refractory asthma manifests with persistent symptoms despite the use of high-dose corticosteroids and long-acting β2-agonists, and poses a major healthcare challenge. Over the past few years has been Dr. Tu’s development of a new research dimension in his laboratory in the field of asthma. He initiated these studies through collaborations with Drs. Reynold A. Panettieri and Thomas Casale. Current research projects are funded by NIH, American Asthma Foundation and State of Nebraska. The long-term objective of Dr. Tu’s research is to understand the molecular mechanisms of therapeutic resistance and to develop new strategies to overcome such resistance in refractory asthma.
 

Publications and Presentations

Books

  • , Sixth Edition
  • , 91-105

Articles

  • , 150, 721-726.e1.
  • , 10(9):, 670
  • , 143(2):, 778-781
  • , 8(1):, 15543.
  • , 46:, 1-14.
  • , 234(1):, 802-815
  • , 17(1):, 179.
  • , 35, 9833-9843
  • , 51, DOI: 10.1165/rcmb.2014-0319OC
  • , 16, 441
  • , 24, 6922–6932
  • , 32, 4814-4824
  • , 85:, 1454-62
  • , 130, 968-976
  • , 53:, 2102-14
  • , 342, 305-11.
  • , 8:, 2505-14
  • , 54:, 647-59
  • , 53:, 95-108
  • , 130, 1521-1531
  • , 342, 305-311
  • , 286, 25813-25822
  • , 584, 4570-4574
  • , 334, 703-709
  • , 67, 2665-2678
  • , 285
  • , 333, 393-403.
  • , 24, 709-721
  • , 67, 2665-2678
  • , 69, 5743-5751
  • , 69, 5743-51
  • , 28, 1853-1863
  • , 72, 73-85
  • , 25, 3719-34
  • , 20, 544-59
  • , 281, 4746-4753
  • , 389, 89-105
  • , 278
  • , 23, 213-224
  • , 10(9), 670

Publications

  • , 23, 584.3
  • , 23, 585.6
  • , 21, 554.23
  • , 21, 569.13

Presentations

Awards and Honors

  • Provisional-REGULATOR OF G-PROTEIN SIGNALLING 2 AND PROSTATE CANCER (Patent No: 60/881992), 2007