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Drug Discovery & Delivery Core Fee Schedule

Description Assisted Rate Unassisted Rate/Hour
One Time/Per Sample performed by technician $35 per Sample $25 per Sample
Trained person to run instrument without assistance $20/hr $10/hr

We have the ability to provide access to the following equipment throughout the university.

Services Equipment Location
In Vitro Drug Screen >1,000 drugs and drug-like compounds Criss I, 410, Criss III, 361
In silico Drug Screening Operatta & DM Dynamics (multiplex confocal imaging for small molecule screens) Criss II, 321
In vitro Drug Screening Biacore 8K Surface Plasmon Resonance Criss II, 281
scRNA Seq for In Silico Screen scRNA seq 10XGenomics Criss II, 321
scRNA Seq for In Silico Screen Zeiss Laser Microdissection with PALM MicroBeam suitable for laser microdissection Criss I, 407
scRNA Seq for In Silico Screen Arcturus PixCell II Laser Capture Dissection Microscope Criss I, 407
In silico Drug Screening, Bioinformatics and Structural Studies Microway 4U High Performance Analysis server (768 Gbytes memory, 32 Tbytes storage) Criss II, 311A
In silico Drug Screening, Structural Studies and Molecular Dynamics Simulations Microway 24 nodes GPU-based High Performance Computer (HPC) cluster (total of 1.43 Tbytes memory and 162 Tbytes storage space) University Data Center
In vivo drug distribution in tissue sections UltrafileXtreme MALDI-MS System Criss II, 303
Peptide Synthesis CEM Liberty microwave automated peptide synthesizer Criss II, 304
Positional Scanning Peptide Library AdvancedChemtec LabMate synthesizer Criss II, 304
Peptide Synthesis Two Gilson Dual Pump HPLCs for peptide purification Criss II, 304
Chemical and Peptide Synthesis/Characterization Jasco J810 Spectropolarimeter Criss II, 303
Chemical and Peptide Synthesis/Characterization Bruker 400 MHz NMR Spectrometer Rigge, 216
Ex vivo Drug Validation 6 Culture Hoods Criss I, 406, 410
In vivo Drug Screening and Validation Zebrafish system Criss I, 217
Chemical Synthesis Thermo Q Exactive quadrople orbitrap hybrid mass spectrometer with Thermo Vanquish UHPLC Criss II, 303
Chemical Synthesis/Purification for Scale-up Biotage Isolera Criss I, 506
Chemical Synthesis/Purification for Scale-up Biotage SP1 Criss III, 361
Chemical Synthesis Heidolph Rotary Evaporator with PC3000 Vario Pump Criss III, 361
Chemical Synthesis Heidolph Rotary Evaporator with PC3000 Vario Pump Criss I, 506
Chemical Synthesis/Purification, Drug Formulation Millrock LD85 Freeze Dryer Criss III, 273
Chemical Synthesis/Purification, Drug Formulation Labconco Freezone 4.5 Freeze Dryer Criss III, 273
Drug Formulation TA Instruments Discovery DSC25 Differential Scanning Calorimeter Criss III, 361
Drug Formulation TA Instruments Discovery TGA55 Thermogravimetric Analyzer Criss III, 361
Drug Formulation TA Instruments AR-G2 Rheometer Criss III, 273
Drug Formulation Malvern Mastersizer 2000, Sciroco 2000, Hydro2000 Criss III, 273
Cytotoxicity Assays BioTek Synergy H1 Hybrid Plate Reader Criss III, 272
ADME Assays, PK/PD Determination AB-Sciex 5500 Qtrap LC/MS/MS equipped with an ExionLC HPLC Criss III, 361
ADME Assays, PK/PD Determination AB-Sciex 3200 Qtrap LC/MS/MS equipped with an Agillent 1200 LC Criss III, 275
ADME Assays, PK/PD Determination Shimadzu Prominence LC-2030C 3D Criss III, 273