Josef (Jody) Derek Franke, PhD

Department

Chemistry and Biochemistry

Position

Resident Assistant Professor

Books

• Springer Publishing
  Franke, JD. Approaches for using animal models to identify loci that genetically interact with human disease-causing point mutations. In Vitro Mutagenesis Protocols (3rd Edition) 2010, 634:203-213. PMID 20676986. , p. 203-213 2010

Articles

• Biotechniques
  Erythrosin B: a versatile colorimetric and fluuorescent vital dye for bacteria. Josef D Franke, Ann L Braverman, Alison M Cunningham, Erin Eberhard and Greg Perry
  68, p. 7 - 13 2019
• FEMS MIcrobiology Letters
  Sterol synthesis is essential for viability in Gemmata obscuriglobusLuke R. Gudde, Martin Hulce, Alexander H. Largen and Josef D. FrankeFEMS Microbiology LettersVolume 366Issue 3
  N/A, p. N/A 2018
• Antonie Van Leeuwenhoek
  Assembly of a complete genome sequence for Gemmata obscuriglobus reveals a novel prokaryotic rRNA operon gene architecture.Josef D. Franke, Wilson R. Blomberg, Robert T. Todd, Robert W. Thomas and Anna M. Selmecki
  111(11), p. 2095-2105 2018
• Journal of Microbiological Methods
  Development of a chemically-defined minimal medium for studies on growth and protein uptake of Gemmata obscuriglobusHenry P. Mishek, Stephen A. Stock, Jacqueline D.E Florick, Wilson R. Blomberg, Josef D. Franke
  145, p. 40-46 2017
• Bioconjugate Chemistry
  Fluorogen activating protein-affibody probes: Modular, no-wash measurement of epidermal growth factor receptors. Wang Y, Telmer CT, Schmidt BF, Franke JD, Ort S, Arndt-Jovin DJ and Bruchez, MP Bioconjugate Chemistry. DOI: 10.1021/bc500525b
  26 (1), p. 137-144 2015
• Proteins
  Atomic structure of the nuclear pore complex targeting domain of a Nup116 homologue from the yeast, Candida glabrata. Sampathkumar P, Kim SJ, Manglicmot D, Bain KT, Gilmore J, Gheyi T, Phillips J, Pieper U, Fernandez-Martinez J, Franke JD, Matsui T, Tsuruta H, Atwell S, Thompson DA, Emtage JS, Wasserman SR, Rout MP, Sali A, Sauder JM, Almo SC, Burley SK. Proteins. PMID: 22544723
  80(8), p. 2110-2116 2012
• Journal of Cell Biology
  Structure-function mapping of a heptameric module in the nuclear pore complex. Fernandez-Martinez J, Phillips J, Sekedat MD, Diaz-Avalos R, Velazquez-Muriel J, Franke JD, Williams R, Stokes DL, Chait BT, Sali A, Rout MP. Journal of Cell Biology. PMID: 22331846
  196 (4), p. 419-34 2012
• Proteins
  Structure of the C-terminal domain of Saccharomyces cerevisiae Nup133, a component of the nuclear pore complex. Sampathkumar P, Gheyi T, Miller SA, Bain KT, Dickey M, Bonanno JB, Kim SJ, Phillips J, Pieper U, Fernandez-Martinez J, Franke JD, Martel A, Tsuruta H, Atwell S, Thompson DA, Emtage JS, Wasserman SR, Rout MP, Sali A, Sauder JM, Burley SK. Proteins. PMID: 21365675
  79 (5), p. 1672-2 2011
• Protein Science
  A novel method for the production of in vivo-assembled, recombinant Escherichia coli RNA polymerase lacking the ? C-terminal domain. Twist KA, Husnain SI, Franke JD, Jain D, Campbell EA, Nickels BE, Thomas MS, Darst SA, Westblade LF. PMID: 21416542
  20(6), p. 986-995 2011
• Developmental Biology
  Nonmuscle myosin II is required for cell proliferation, cell sheet adhesion and wing hair morphology during wing morphogenesis. Franke JD, Montague RA and Kiehart DP. PMID: 20599890.
  345 (2), p. 117-32 2010
• Proc Natl Acad Sci U S A
  Endocytosis-like protein uptake in the bacterium Gemmata obscuriglobus.Lonhienne TG, Sagulenko E, Webb RI, Lee KC, Franke J, Devos DP, Nouwens A, Carroll BJ, Fuerst JA. 
  107(29), p. 12883-12888 2010
• Proteins
  Structures of the autoproteolytic domain from the Saccharomyces cerevisiae nuclear pore complex component, Nup145.  Parthasarathy Sampathkumar, Sinem A. Ozyurt, Johnny Do, Kevin T. Bain, Mark Dickey, Logan A. Rodgers, Tarun Gheyi, Andrej Sali, Seung Joong Kim, Jeremy Phillips, Ursula Pieper, Javier Fernandez-Martinez, Joseph D. Franke, Anne Martel,Hiro Tsuruta, Shane Atwell, Devon A. Thompson, J. Spencer Emtage, Stephen R. Wasserman, Michael P. Rout, J. Michael Sauder, and Stephen K. Burley
  78(8), p. 1992-1998 2010
• PLoS Biology
  The Compartmentalized Bacteria of the Planctomycetes-Verrucomicrobia-Chlamydiae Superphylum Have Membrane Coat-Like Proteins.Rachel Santarella-Mellwig, Josef Franke, Andreas Jaedicke, Matyas Gorjanacz, Ulrike Bauer, Aidan Budd, Iain W. Mattaj, Damien P. Devos
  (8)1, p. 1-11 2010
• Human Molecular Genetics
  An MYH9 Human Disease Model in Flies: site-directed mutagenesis of the Drosophilanonmuscle myosin II results in hypomorphic alleles with dominant character.Franke JD, Montague RA, Rickoll  WL and Daniel P. Kiehart.
  16(24), p. 3160-3173 2007
• Cell Motility and the Cytoskeleton
  Native nonmuscle myosin II stability and light chain binding in Drosophila melanogaster. Franke JD, Boury AL, Gerald NJ and Kiehart DP
  63(10), p. 604-622 2006
• Current Biology
  Nonmuscle Myosin II Generates Forces that Transmit Tension and Drive Contraction in Multiple Tissues during Dorsal ClosureFranke JD, Montague RA, Kiehart DP. 
  15(24), p. 2208-2201 2005
• Current Biology
  Myosin VIIA Defects, which Underlie the Usher 1B Syndrome in Humans, Lead to Deafness in Drosophila. Todi S, Franke JD, Kiehart DP, Eberl D
  15(9), p. 862-868 2005
• Blood
  Rod mutations associated with MYH9-related disorders disrupt nonmuscle myosin-IIA assembly.Franke JD, Dong F, Rickoll WL, Kelley MJ, Kiehart DP
  105(1), p. 161-169 2004
• Genetics
  Drosophila crinkled, mutations of which disrupt morphogenesis and cause lethality, encodes fly myosin VIIA. Kiehart DP, Franke JD, Chee MK, Montague RA, Chen TL, Roote J, Ashburner M. 
  168(3), p. 1337-1352 2004
• Current Biology
  Actin dynamics: the arp2/3 complex branches out. (REVIEW)Kiehart DP and Franke, JD.
  12(16), p. R557-559 2002

Federal

• UNO Subgrant Number: 2013-035. National Institutes of Health Award to Carnegie Mellon University 2U54RR022241-06
  Subgrant Project Title: Continued development of intracellular fluoromodules
  Award Amount: $15,000.
  Award Duration: 09/15/2012 – 07/14/2013.

• Studying the structure of the NPC core scaffold at high resolution
  F32 GM082029 (National Institutes of Health Postdoctoral Fellowship)

Foundation/Association

• Characterizing the molecular mechanisms by which rod mutations in MYH6, MYH7 and MYH11 cause cardiac diseases.
  American Heart Association Postdoctoral Fellowship (10POST3160008)

Other

• Improved Separation of Carotenoids from Gemmata obscuriglobus
  CURAS Faculty Research Fund, Creighton University

Awards

• American Heart Association Postdoctoral Fellowship
  Principal Investigator: Josef D Franke Fellowship Number: 10POST3160008 (American Heart Association Postdoctoral Fellowship) Project Title: Characterizing the molecular mechanisms by which rod mutations in MYH6, MYH7 and MYH11 cause cardiac diseases. Award duration: July 1, 2010 - June 30, 2012.
  American Heart Association