Close Menu
Richard V . Goering, PhD

Professor

Medical Microbiology and Immunology

R Goering

Contact

School of Medicine
Med Microbiology & Immunology
Medical Microbiology and Immunology (Doctorate)
Medical Microbiology and Immunology (Master of Science)
Graduate School
CRISS II - Criss 2 - 514D

Richard V . Goering, PhD

Professor

Medical Microbiology and Immunology

Examples of the most recent publications can be obtained from this PubMed link.

Research Focus

My laboratory is actively involved in the application of molecular techniques to the diagnosis, study of antibiotic resistance, and the epidemiological analysis (i.e., molecular epidemiology) of infectious diseases with a special emphasis on Clostridium difficile, staphylococci, and staphylococcal diseases. We are especially interested in the impact whole genome sequencing (WGS) is having on these areas of investigation.  Especially with regard to epidemiological analysis, the use of WGS remains in need of clarified sequencing protocols and guidelines for bioinformatic data analysis and interpretation - areas we are actively pursuing with a variety of collaborators both corporate and academic.

Department

Med. Microbiology & Immunology

Position

Professor

Books

  • Advanced Techniques in Diagnostic Microbiology
    Goering Richard V., Molecular Typing Techniques: State of the Art [Book Chapter] 2018
  • Molecular Microbiology : Diagnostic Principles and Practice
    Besser John, The impact of molecular diagnostics on surveillance of foodborne infections [Book Chapter] 2016
  • Advanced Techniques in Diagnostic Microbiology
    Goering Richard V., Molecular Typing Techniques: State of the Art [Book Chapter] 2013
  • Molecular Techniques for the Study of Hospital-Acquired Infection
    Goering Richard V., Restriction Analysis Techniques [Book Chapter] 2011
  • Molecular Techniques for the Study of Hospital-Acquired Infection
    Stemper M. E., Pulsed-Field Gel Electrophoresis [Book Chapter] 2011
  • Goering Richard V, Medical Microbiology 2007

Articles

  • Tenover F. C., Interpreting chromosomal DNA restriction patterns produced by pulsed- field gel electrophoresis 1995

Publications

  • Medicina (Kaunas, Lithuania)
    Gaber Yasser, Emergence and Genomic Characterization of a spa Type t4407 ST6-SCC mec Type IVa Methicillin-Resistant Staphylococcus aureus Strain Isolated from Al-Karak Hospital, Jordan
    60:2 2024
  • Medicina (Kaunas, Lithuania)
    Gaber Yasser, Emergence and Genomic Characterization of a spa Type t4407 ST6-SCCmec Type IVa Methicillin-Resistant Staphylococcus aureus Strain Isolated from Al-Karak Hospital, Jordan
    60:2, p. 295 2024
  • Aktuelle Dermatologie
    Schlatterer Kathrin, Community-associated Methicillin-Resistant Staphylococcus aureus (ca-MRSA) as a Pandemic Pathogen: Risk Factors and Implications for Healthcare
    49:1/02, p. 68 - 75 2023
  • Diagnostic Microbiology and Infectious Disease
    Tickler Isabella A., Mobile genetic elements responsible for discordant Staphylococcus aureus phenotypes and genotypes in the same blood culture bottle
    98:4 2020
  • Diagnostics
    Goyal Manisha, Retrospective definition of Clostridioides difficile PCR ribotypes on the basis of whole genome polymorphisms
    10:12 2020
  • Journal of Antimicrobial Chemotherapy
    Cheknis Adam, Characterization of Clostridioides difficile isolates recovered from two Phase 3 surotomycin treatment trials by restriction endonuclease analysis, PCR ribotyping and antimicrobial susceptibilities
    75:11, p. 3120 - 3125 2020
  • Journal of Hospital Infection
    Tickler I. A., Presence of Clostridioides difficile and multidrug-resistant healthcare-associated pathogens in stool specimens from hospitalized patients in the USA
    106:1, p. 179 - 185 2020
  • Anaerobe
    Tickler Isabella A., Changes in molecular epidemiology and antimicrobial resistance profiles of Clostridioides (Clostridium) difficile strains in the United States between 2011 and 2017
    60 2019
  • Antimicrobial agents and chemotherapy
    Goering Richard V., Emergence of oxacillin resistance in stealth methicillin-resistant staphylococcus aureus due to mecA sequence instability
    63:8 2019
  • Journal of clinical microbiology
    Tickler Isabella A., Streptococcus agalactiae strains with chromosomal deletions evade detection with molecular methods
    57:4 2018
  • mBio
    Challagundla Lavanya, Range expansion and the origin of USA300 north american epidemic methicillin-resistant Staphylococcus aureus
    9:1 2018
  • Diagnostic Microbiology and Infectious Disease
    Tickler Isabella A., Continued Expansion of USA300-Like Methicillin-Resistant Staphylococcus Aureus (MRSA) among Hospitalized Patients in the United States
    88:4, p. 342 - 347 2017
  • Foodborne Pathogens and Disease
    Lopez-Valladares G., Lineage II (Serovar 1/2a and 1/2c) Human Listeria Monocytogenes Pulsed-Field Gel Electrophoresis Types Divided into PFGE Groups using the Band Patterns Below 145.5 Kb
    14:1, p. 8 - 16 2017
  • Journal of Medical Microbiology
    BenDarif Elloulu, Characterization of methicillin-resistant Staphylococcus aureus isolated at Tripoli Medical Center, Libya, between 2008 and 2014
    65:12, p. 1472 - 1475 2016
  • Clinical Microbiology and Infection : The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases
    Butin M., Wide geographical dissemination of multiresistant Staphylococcus capitis NRCS-A clone in neonatal intensive care units
    22:1, p. 46 - 52 2016
  • Journal of Clinical Microbiology
    Kadlec K., Direct repeat unit (dru) typing of methicillin-resistant Staphylococcus pseudintermedius from dogs and cats
    53:12, p. 3760 - 3765 2015
  • Foodborne Pathogens and Disease
    Lopez-Valladares G., Division of Human Listeria monocytogenes Pulsed-Field Gel Electrophoresis (PFGE) Types Belonging to Lineage I (Serovar 4b, 1/2b, and 3b) into PFGE Groups
    12:5, p. 447 - 453 2015
  • Journal of Clinical Microbiology
    Spinali S., Microbial Typing by Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry: Do We Need Guidance for Data Interpretation?
    53:3, p. 760 - 765 2015
  • Clinical Microbiology and Infection
    Nimmo G. R., ST2249-MRSA-III: a second major recombinant methicillin-resistant Staphylococcus aureus clone causing healthcare infection in the 1970s 2015
  • Antimicrobial Agents and Chemotherapy
    Locke Jeffrey B., Identification and characterization of linezolid-resistant cfr-positive Staphylococcus aureus USA300 isolates from a New York City medical center
    58:11, p. 6949 - 6952 2014
  • Antimicrobial Agents and Chemotherapy
    Locke Jeffrey B., Linezolid-resistant Staphylococcus aureus strain 1128105, the first known clinical isolate possessing the cfr multidrug resistance gene
    58:11, p. 6592 - 6598 2014
  • Journal of Clinical Microbiology
    Leopold Shana R., Bacterial whole-genome sequencing revisited: portable, scalable, and standardized analysis for typing and detection of virulence and antibiotic resistance genes
    52:7, p. 2365 - 2370 2014
  • Diagnostic microbiology and infectious disease
    Fowler Randal C., Whole Genome Mapping of the First Reported Case of KPC-2-positive Klebsiella pneumoniae ST258 in Nebraska
    79:3, p. 384 - 386 2014
  • Journal of clinical microbiology
    Carroll Karen C., Multicenter evaluation of the verigene clostridium difficile nucleic acid assay
    51:12, p. 4120 - 4125 2013
  • Antimicrobial Agents and Chemotherapy
    Scharn Caitlyn R., Transduction of Staphylococcal Cassette Chromosome mec Elements between Strains of Staphylococcus aureus
    57:11, p. 5233 - 5238 2013
  • Journal of Global Antimicrobial Resistance
    Penn C., Wound Infections Caused by Inducible Meticillin-Resistant Staphylococcus Aureus Strains
    1:2, p. 79 - 83 2013
  • PloS one
    Kurt Kevin, Subpopulations of Staphylococcus aureus Clonal Complex 121 Are Associated with Distinct Clinical Entities
    8:3 2013
  • Toxicological Sciences
    Kimber I., Toxic Shock Syndrome: Characterization of Human Immune Responses to TSST-1 and Evidence for Sensitivity Thresholds
    134:1, p. 49 - 63 2013
  • Tropical Biomedicine
    Ghasemzadeh-Moghaddam H., Methicillin sensitive Staphylococcus aureus (MSSA) isolates as a potential source for the emergence of USA 300 methicillin resistant Staphylococcus aureus (MRSA) in Malaysia
    29:3, p. 429 - 433 2012
  • International Journal of Infectious Diseases
    Neela Vasanthakumari, Stenotrophomonas maltophilia in Malaysia
    16:8, p. e603 - e607 2012
  • Epidemiology research international
    Robledo Iraida E., Dissemination and Molecular Epidemiology of KPC-Producing Klebsiella pneumoniae Collected in Puerto Rico Medical Center Hospitals during a 1-Year Period
    2011, p. 1 - 8 2011
  • International journal of infectious diseases
    Lim K.T., PP-026 Enhanced discrimination of pandemic clone ST239-methicillin-resistant Staphylococcus aureus in a tertiary hospital in Malaysia by mec-associated direct repeat unit and spa typing
    15, p. S52 - S52 2011
  • Journal of clinical microbiology
    Tenover Fred C., Impact of strain type on detection of toxigenic Clostridium difficile
    48:10, p. 3719 - 3724 2010
  • Infection, Genetics and Evolution
    Goering Richard V., Pulsed Field Gel Electrophoresis: A Review of Application and Interpretation in the Molecular Epidemiology of Infectious Disease
    10:7, p. 866 - 875 2010
  • Journal of clinical microbiology
    Shore Anna C., Enhanced discrimination of highly clonal ST22-methicillin-resistant Staphylococcus aureus IV isolates achieved by combining spa, dru, and pulsed-field gel electrophoresis typing data
    48:5, p. 1839 - 1852 2010
  • Antimicrobial Agents and Chemotherapy
    Wolter Daniel J., Surveillance of Carbapenem-Resistant Pseudomonas aeruginosa Isolates from Puerto Rican Medical Center Hospitals: Dissemination of KPC and IMP-18 beta-Lactamases
    53:4, p. 1660 - 1664 2009
  • Morbidity and Mortality Weekly Report
    Lledo W., Guidance for Control of Infections With Carbapenem-Resistant or Carbapenemase-Producing Enterobacteriaceae in Acute Care Facilities
    58:10, p. 256 - 260 2009
  • Antimicrobial agents and chemotherapy
    Wolter Daniel J., Phenotypic and enzymatic comparative analysis of the novel KPC variant KPC-5 and its evolutionary variants, KPC-2 and KPC-4
    53:2, p. 557 - 562 2009
  • Microbial Drug Resistance
    Chung Marilyn, Molecular typing of methicillin-resistant Staphylococcus aureus by pulsed-field gel electrophoresis
    6:3, p. 189 - 198 2009
  • Journal of Antimicrobial Chemotherapy
    Tenover Fred C., Methicillin-resistant Staphylococcus aureus strain USA300
    64:3, p. 441 - 446 2009
  • Clinical Microbiology and Infection
    Goering Richard V., Comparative genomic analysis of European and Middle Eastern community-associated methicillin-resistant Staphylococcus aureus (CC80:ST80-IV) isolates by high-density microarray
    15:8, p. 748 - 755 2009
  • Wolter Daniel J., Isolation and characterization of an epidemic methicillin-resistant Staphylococcus aureus 15 variant in the central United States 2008
  • Clinical Microbiology and Infection
    Goering Richard V., Usefulness of mec-associated direct repeat unit (dru) typing in the epidemiological analysis of highly clonal methicillin-resistant Staphylococcus aureus in Scotland
    14:10, p. 964 - 969 2008
  • Clinical Infectious Diseases
    Wolter Daniel J., Emergence of Carbapenem Resistance in Pseudomonas aeruginosa Isolates from a Patient with Cystic Fibrosis in the Absence of Carbapenem Therapy
    46:12, p. e137 - e141 2008
  • Clinical Microbiology and Infection
    Wolter D. J., Allelic variation in genes encoding Panton-Valentine leukocidin from community-associated Staphylococcus aureus
    13:8, p. 827 - 830 2007
  • Journal of Clinical Microbiology
    Goering Richard V., Epidemiologic distribution of the arginine catabolic mobile element among selected methicillin-resistant and methicillin-susceptible Staphylococcus aureus isolates
    45:6, p. 1981 - 1984 2007
  • International journal of antimicrobial agents
    Larsen A., P1573 Characterisation of an MRSA clone in Denmark similar to USA300 in PFGE pattern but with different properties: a potential pitfall when identifying USA300 isolates
    29, p. S441 - S441 2007
  • International journal of antimicrobial agents
    Rossney A., P1306 Direct repeat unit typing to differentiate methicillin-resistant Staphylococcus aureus isolates in Ireland indistinguishable by pulsedfield gel electrophoresis
    29, p. S361 - S361 2007
  • Journal of Clinical Microbiology
    Bonnstetter K. K., Rapid multiplex PCR assay for identification of USA300 community-associated methicillin-resistant Staphylococcus aureus isolates
    45:1, p. 141 - 146 2007
  • Antimicrobial Agents and Chemotherapy
    Hossain Ashfaque, Plasmid-mediated carbapenem-hydrolyzing enzyme KPC-2 in an Enterobacter sp.
    48:11, p. 4438 - 4440 2004
  • Diagnostic Microbiology and Infectious Disease
    Wolter Daniel J., Multidrug resistance associated with mexXY expression in clinical isolates of Pseudomonas aeruginosa from a Texas hospital
    50:1, p. 43 - 50 2004
  • Journal of Molecular Diagnostics
    Cooper Kara L. F., Development of a universal probe for electronic microarray and its application in characterization of the Staphylococcus aureus po/C gene
    5:1, p. 28 - 33 2003
  • Goering Richard V., Questions study on Escherichia coli susceptibility 2002
  • Molecular Microbiology
    Mann Paul A., EmtA, a rRNA methyltransferase conferring high-level evernimicin resistance
    41:6, p. 1349 - 1356 2001
  • Clinical Microbiology Newsletter
    Goering Richard V., Molecular strain typing for the clinical laboratory
    22:22, p. 169 - 173 2000
  • Reviews in Medical Microbiology
    Goering R. V., The molecular epidemiology of nosocomial infection
    11:3, p. 145 - 152 2000
  • JAMA - Journal of the American Medical Association
    Wiener Janis, Multiple antibiotic-resistant Klebsiella and Escherichia coli in nursing homes
    281:6, p. 517 - 523 1999
  • JAMA : the journal of the American Medical Association
    Wiener J, Multiple antibiotic-resistant Klebsiella and Escherichia coil in nursing homes
    281:6, p. 517 - 523 1999
  • Infection Control and Hospital Epidemiology
    Tenover Fred C., How to Select and Interpret Molecular Strain Typing Methods for Epidemiological Studies of Bacterial Infections
    18:6, p. 426 - 439 1997
  • European Journal of Clinical Microbiology and Infectious Diseases
    Tassios P. T., Distinct genotypic clusters of heterogeneously and homogeneously methicillin-resistant Staphylococcus aureus from a Greek hospital
    16:2, p. 170 - 173 1997
  • Journal of clinical microbiology
    Bingen Edouard, Molecular epidemiology provides evidence of genotypic heterogeneity of multidrug-resistant Pseudomonas aeruginosa serotype O:12 outbreak isolates from a pediatric hospital
    34:12, p. 3226 - 3229 1996
  • Taylor D. E., Diversity among Helicobacter pylori isolates [1] 1996
  • Journal of Medical Microbiology
    Cookson B. D., Inter-centre comparison of pulsed-field gel electrophoresis for the typing of methicillin-resistant Staphylococcus aureus
    44:3, p. 179 - 184 1996
  • Cavallo J. D., Susceptibility of nosocomial gram-positive cocci to teicoplanin and other antibiotics 1995
  • European Journal of Clinical Microbiology and Infectious Diseases
    Goering R. V., Usefulness of pulsed-field gel electrophoresis in the epidemiological analysis of staphylococcus aureus isolates with decreased susceptibility to teicoplanin
    14:SUPPL. 1, p. S3 - S5 1995
  • Infectious Diseases in Obstetrics and Gynecology
    Rupp M. E., Repeated Recovery of Staphylococcus saprophyticus From the Urogenital Tracts of Women
    2:5, p. 218 - 222 1995
  • Journal of Burn Care and Rehabilitation
    Snyder Lori L., Methicillin-Resistant staphylococcus aureus eradication in a burn center
    14:2, p. 164 - 168 1993
  • Journal of clinical microbiology
    Goering R. V., Rapid method for epidemiological evaluation of gram-positive cocci by field inversion gel electrophoresis
    30:3, p. 577 - 580 1992
  • Journal of clinical microbiology
    Shayegani M., Molecular relatedness of Staphylococcus epidermidis isolates obtained during a platelet transfusion-associated episode of sepsis
    29:12, p. 2768 - 2773 1991
  • Journal of clinical microbiology
    Goering R. V., Rapid field inversion gel electrophoresis in combination with an rRNA gene probe in the epidemiological evaluation of staphylococci
    28:3, p. 426 - 429 1990
  • Clinical Infectious Diseases
    Goering Richard V., Heterogeneity in ampr-ampc gene interaction in enterobacter cloacae
    10:4, p. 786 - 792 1988
  • Antimicrobial agents and chemotherapy
    Weber D. A., Tn4201, a β-lactamase transposon in Staphylococcus aureus
    32:8, p. 1164 - 1169 1988
  • Reviews of infectious diseases
    Goering R. V., Studies with Ciprofloxacin
    10, p. S48 - S49 1988
  • Antimicrobial agents and chemotherapy
    Gates M. L., Evidence for multiple forms of type I chromosomal β-lactamase in Pseudomonas aeruginosa
    30:3, p. 453 - 457 1986
  • Antimicrobial agents and chemotherapy
    Sanders C. C., Selection of multiple antibiotic resistance by quinolones, β-lactams, and aminoglycosides with special reference to cross-resistance between unrelated drug classes
    26:6, p. 797 - 801 1984
  • Antimicrobial agents and chemotherapy
    Sanders C. C., Influence of clindamycin on derepression of β-lactamases in Enterobacter spp. and Pseudomonas aeruginosa
    24:1, p. 48 - 53 1983
  • Unknown Journal
    Preheim L. C., Emergence of resistance to β-lactam and aminoglycoside antibiotics during moxalactam therapy of Pseudomonas aeruginosa infections
    22:6, p. 1037 - 1041 1982
  • Antimicrobial agents and chemotherapy
    Sanders C. C., In vitro antagonism of beta-lactam antibiotics by cefoxitin
    21:6, p. 968 - 975 1982
  • Antimicrobial agents and chemotherapy
    Goering R. V., Antagonism of carbenicillin and cefamandole by cefoxitin in treatment of experimental infections in mice
    21:6, p. 963 - 967 1982
  • Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis
    Goering R. V., Mutants of Staphylococcus aureus deficient in recombinational repair. Improved isolation by selecting for mutants exhibiting concurrent sensitivity to ultraviolet radiation and N-methyl-N′-nitro-N-Nutrosoguanidine
    60:3, p. 279 - 289 1979
  • Antimicrobial agents and chemotherapy
    Sanders C. C., In vitro studies with Sch 21420 and Sch 22591
    14:2, p. 178 - 184 1978
  • Antimicrobial agents and chemotherapy
    Goering R. V., Comparison of 5-episisomicin (Sch 22591), gentamicin, sisomicin, and tobramycin in treatment of experimental Pseudomonas infections in mice
    14:6, p. 824 - 828 1978
  • Genetics
    Wyman L., Genetic control of chromosomal and plasmid recombination in Staphylococcus aureus
    76:4, p. 681 - 702 1974
  • Journal of bacteriology
    Goering R. V., Mutants of Staphylococcus aureus with increased sensitivity to ultraviolet radiation.
    106:1, p. 157 - 161 1971

Presentations

  • 144. Goering, R.V., M. Bensaci, H. Patel*, and G. Thorne. Epidemiological Analysis of Methicillin-Resistant Staphylococcus aureus Isolates from Tedizolid Clinical Studies. Abstr. 25th Eur. Congr. Clin. Microbiol. Infect. Dis. EP086 2015
  • A.R. Larsen*, R.V. Goering, L.V. Pallesen, R. Skov. 2005. Ten-year of Community-Acquired Methicillin-Resistant Staphylococcus aureus ST80-IV clone in Denmark. 15th Eur. Congr. Clin. Microbiol. Infect. Dis. P1177 2005
  • Chatterjee*, S.D. Plummer, B. Heybrock, K. Eischen, and R. V. Goering. 2004. Infection Control Goes Molecular: The Role of Pulsed Field Gel Electrophoresis in the Practice of Hospital Epidemiology at a Childrens Hospital. 14th Annu. Meeting Soc. Healthcare Epidemiol. Amer. 267 2004
  • Chatterjee*, T. Bardon, N. Cornish, S. Plummer, B. Heybrock, K. Eischen, R.V. Goering, S. Lazoritz. 2005. Identification and Control of a Clonal Outbreak of Methicillin-Resistant Staphylococcus aureus Infections at a Level 3 Neonatal Intensive Care Unit. 15th Annu. Meeting Soc. Healthcare Epidemiol. Amer. 125 2004
  • 1. Goering, R.V.* and K.L.F. Cooper. 2000. Improved Epidemiological Analysis of Methicillin Resistant Staphylococcus aureus by RAPD Using a Thermostable Polymerase with 3 to 5 Proofreading Activity. Fifth Internat. Meeting Bact. Epidemiol. Markers (Noordwijkerhout, The Netherlands). S7-02 2000
  • 2. Goering, R.V.*, M. Fincham, F. Vandenesch, and J. Etienne. 2000. A Genotypic Comparison of Staphylococcus lugdunensis Clinical Isolates of Diverse Geographic Origin. 10th Eur. Congr. Clin. Microbiol. Infect. Dis. MoP338. 2000
  • 3. Goering, R.V.* 2000. Genomic Organization of Ribosomal RNA Genes in Staphylococci. 9th Internat. Symp. Staph. and Staph. Infect. #93/HP13. 2000
  • 4. Goering, R.V.* 2000. An Integrated Approach to the Epidemiological Analysis of Nosocomial Pathogens Using a Combination of Pulsed Field Gel Electrophoresis and PCR. Fifth Internat. Meeting Bact. Epidemiol. Markers (Noordwijkerhout, The Netherlands). P040 2000
  • Presentations at four other Japanese hospitals 10/20/99-10/23/99 1999
  • Japan Antibiotics Symposium, 10/19/99; 1999
  • University of Tokyo, 10/19/99 1999
  • Molecular epidemiology of infectious disease, Copenhagen, Denmark, 10/14/99 1999
  • APIC Minnesota, 10/9/99 1999
  • ICAAC 9/24/99 1999
  • APIC Florida, 9/17/99 1999
  • IMSS Mexico City Nosocomial Infection Workshop, 8/24/99-8/29/99 1999
  • WIP, 5/5/99 1999
  • Mt. Siani Hospital, NY, 4/26/99 1999
  • SHEA epiedmiology workshop, 4/17/99 1999
  • NYAS, 3/17/99 1999
  • NYAS 3/17/99 1999
  • ASM, 3/2/99 1999
  • Dept. Pathology, CUSOM, 2/18/99 1999

Awards

  • “Highly Commended” recognition by The Society of Authors and the Royal Society of Medicine in London
    The textbook that I’ve co-authored with others in the UK (i.e., Mims Medical Microbiology) was awarded “Highly Commended” recognition by The Society of Authors and the Royal Society of Medicine in London at a ceremony we all attended on October 18th, 2005 at the Royal Society of Medicine in London.