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Jee-Yeon Hwang, PhD

Assistant Professor

Pharmacology & Neuroscience

Jee-Yeon Hwang

Contact

JeeYeonHwang@creighton.edu
School of Medicine
Pharmacology and Neuroscience
Graduate School
Neuroscience
CRISS II - Criss 2

Jee-Yeon Hwang, PhD

Assistant Professor

Pharmacology & Neuroscience

The studies in Dr. Hwang’s laboratory focus on the role of neuroinflammation, epigenetic regulation, microRNAs and protein regulation and degradation such as ubiquitination and autophagy underlying the pathophysiology of neurological disorders and diseases such as stroke, Alzheimer’s, Parkinson’s, Huntington’s disease. Her lab uses cell culture models and animal models of these diseases. The ultimate goal of her research is to identify potential therapeutic targets for these diseases.
 
In addition, in collaboration with Dr. Melinda Burnett, MD (Neurology, Creighton University School of Medicine), translational research on biomarkers in human patients with Parkinson’s disease is being pursued.
 

Department

Pharmacology and Neuroscience

Position

Assistant Professor

Books

  • Stroke (7th Edition); Pathophysiology, Diagnosis, and Management
    Tuo Yang, Chapter 5 - Molecular and Cellular Mechanisms of Ischemia-Induced Neuronal Death, https://doi.org/10.1016/B978-0-323-69424-7.00005-3, p. 57-73 2021

Articles

  • Cell Reports
    Kyung Min Chung/Jee-Yeon Hwang/Ulrich Hengst, Kyung Min Chung, Hyunha Kim, Cludio Gouveia Roque, Ethan P McCurdy, Trang T T Nguyen, Markus D Siegelin, Jee-Yeon Hwang, Ulrich Hengst Title: A systemic cell stress signal confers neuronal resilience toward oxidative stress in a Hedgehog-dependent manner
    41, p. 111488 2022
  • Cell Reports
    Jee-Yeon Hwang, Hwang JY, Monday HR, Yan J, Gompers A, Buxbaum AR, Sawicka KJ, Singer RH, Castillo PE, Zukin RS. Title: CPEB3-dependent increase in GluA2 subunits impairs excitatory transmission onto inhibitory interneurons in a mouse model of fragile X.
    39, p. 110853 2022
  • Frontiers in Cellular Neuroscience
    Teresa Jover-Mengual, Jee-Yeon Hwang, Title: The Role of NF-B Triggered Inflammation in Cerebral Ischemia. 2021
  • Current Opinion in Neurobiology
    Jee-Yeon Hwang, Title: Autophagy and synaptic plasticity: epigenetic regulation
    Volume 59, p. Pages 207-212 2019
  • International Neurourology Journal
    Jee-Yeon Hwang, Cho CH, Byun HR, Jover-Mengual T, Pontarelli F, Dejesus C, Cho AR, Zukin RS, Hwang JY Title: Gadd45b Acts as Neuroprotective Effector in Global Ischemia-Induced Neuronal Death.
    23 (Suppl1), p. S11-21 2019

Presentations

  • Oral presentation entitled Molecular Mechanisms of Neurodegeneration" at the Research Rounds and Seminars in the Department of Pharmacology and Neuroscience." 2021
  • Oral presentation entitled PI3K/Akt pathway stabilizes the DNA methyltransferase (DNMT) proteins: Implication in Alzheimer's disease." at the Omaha Area Ubiquitin and Aging Research Group Meeting." 2021
  • Poster presentation entitled "The Role of miR-34b/c in Global Ischemic Stroke" at the Internation Stroke Conference 2020 in Los Angeles, CA, USA. 2020
  • Oral presentation entitled CK1 regulates REST abundance by -TrCP dependant ubiquitin/proteasomal degradation" at the Omaha Area Ubiquitin and Aging Research Group Meeting." 2019
  • Poster presentation entitled "miR-34b/c inhibition attenuates ischemia-induced death of hippocampal neurons and rescues aberrant synaptic plasticity and cognitive deficits" at the 10th IBRO World Congress of Neuroscience in Daegu, Korea. 2019
  • Invited talk entitled "Epigenetic regulation of microRNAs in global ischemic stroke" at the University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea. 2019
  • Oral presentation entitled "The role of microRNAs in global ischemic stroke" at the Research Rounds and Seminars in the Department of Pharmacology and Neuroscience. 2019
  • Poster presentation entitled "Inhibition of miR-34b/c rescues hippocampal CA1 neurons and memory deficits in global ischemia" at the annual meeting of Society of Neuroscience in San Diego, CA, USA. 2018