Joan M. Lappe, PhD, RN, CNE
Joan M. Lappe, PhD, RN, CNE

Joan M. Lappe, PhD, RN, CNE

Professor
Associate Dean, College of Nursing Research
College of Nursing

Academic Appointments

Position

  • Professor

Secondary Appointment

  • School of Medicine

Teaching Activity

  • DNP chairperson

Education

  • St. Catherine's School of Nursing,Nursing,1965
  • University of Nebraska Medical Center,B.S.N.,1981
  • Creighton University,M.S.,1985
  • University of Nebraska Medical Center,Ph.D.,1992

Publications and Presentations

Books

  • Lappe, J., Begley, M., Des Mangles, J., Laughlin, A., McMahon, D., Schwartz, M. (2016) Clinical Trial of Dairy in Adolescent Girls: Effect on Bone Accrual. In Nutritional Influences on Bone Health – 9th International Symposium. Editors: Connie M. Weaver, Robin M. Daly, Heike A. Bischoff-Ferrari. Springer-Verlag, London. ISBN: 978-3-319-32415-9 (Print) 978-3-319-32417-3 (Online), Springer Vertag, London, 261-267, 2016
  • Lappe, J., Watson, P., Gilsanz, V., Kalkwarf, H., Hangartner, T., Oberfield, S., Shepherd, J., Zemel, B., Winer, K. (2013). The relationship of weight-bearing physical activity and dietary calcium intake with bone mass accrual in the Bone Mineral Density in Childhood Study cohort. In Nutritional Influences on Bone Health, Edited by P Burckhard, B Dawson-Hughes, and C Weaver. Springer-Verlag, London., Springer Vertag, London, Chapter 31, 325-333, 2013
  • Lappe, J., Heaney, R. The Anti-Cancer Effect of Vitamin D: What do the Randomized Trials Show? In Vitamin D: Physiology, Molecular Biology and Clinical Applications, Editor M Holick., Humana Press, Inc, 2 Ed. , 841-850, 2010
  • Lappe, J.M. Calcium and Cancer, In Nutrition and Health: Bioactive Compounds and Cancer. Editors John A. Milner, and Donato F Romagnolo., Humana Press, Inc, 2010
  • Lappe, J. The Bone Benefits of Calcium and Exercise in Children. In Press, Nutritional Influences on Bone Health, Edited by Peter Burckhardt, B. Dawson-Hughes, & C. Weaver., Springer Vertag, London, 2010
  • Roberts, D., Lappe, Joan M. Management of clients with musculoskeletal disorders. Black, J. and Hokanson Hawks, J. (Eds), Medical-Surgical Nursing: Clinical Management for Positive Outcomes., W.B. Saunders Co., 8th Edition, Chapter 26, 2008

Articles

  • Mishra, R, Chesi, A, Cousminer, DL, Hawa, M, Bradfield, JP, Hodge, KM, Guy, VC,
    Hakonarson, H, Mauricio, D, Schloot, NC, Yderstræde, KB, Voight, BF, Schwartz, S, Boehm, BO, Leslie, RD, Grant, SFA, Kalkwarf, HJ, Lappe, JM, Gilsanz, V, Oberfield, SE, Shepherd, JA, Kelly,A, Zemel, BS.  Relative contribution of type 1 and type 2 diabetes loci to the genetic etiology of adult-onset, non-insulin-requiring autoimmune diabetes. BMC Med. 2017 Apr 25;15(1):88. doi: 10.1186/s12916-017-0846-0., 2017
  • Lappe, J, Watson, P, Travers-Gustafson, D, Recker, R, Garland, C, Gorham, E, Baggerly, K, McDonnell, S. Effect of vitamin D and calcium supplementation on cancer incidence in older women: A randomized trial. JAMA (2017) March 28; 317(12): 1234-43., JAMA: Journal of the American Medical Association, Issue 317, Volume 12, 1234-1243, 2017
  • Lappe, J, McMahon, D, Laughlin, A, Hanson, C, Desmangeles, D, Begley, M, Schwartz, M. The   effect of increasing dairy calcium intake of adolescent girls on changes in body fat and weight. American Journal of Nutrition. (2017) March 15 epub ahead of print doi: 10.3945/ajcn 116.138941, American Journal of Clnical Nutrition, Issue 116, 2017
  • Cohen, C,  Kousteni, S, Brygida Bisikirska, B, Shah, J,  Manavalan, S, Recker, R, Lappe, J, Dempster, D, Zhou, H, McMahon, D, Bucovsky, M, Kamanda-Kosseh, M, Stubby, J, Shane, E. IGF-1 receptor expression on circulating osteoblast progenitor cells predicts tissue-based bone formation rate and response to teriparatide in premenopausal women with idiopathic osteoporosis. JBMR, Feb 2017, in press., Journal of Bone and Mineral Research, 2017
  • Akhter, M, Kimmel, D, Lappe, J, Recker, R.  Effect of macroanatomic bone type and estrogen
            loss on osteocyte lacunar properties in healthy adult women. Calcif Tissue Int. 2017 Jan;    
            30. doi: 10.1007/s00223-017-0247-6., Cacified Tissue International, 2017
  • Vennin, S., Desyatova, A., Turner, J., Watson, P., Lappe, J., Recker, R., Akhter, M. Intrinsic Material Property Differences in Bone Tissue from Patients Suffering Low-Trauma Osteoporotic Fractures, Compared to Matched Non-fracturing Women. Bone 2017 Jan 26. pii: S8756-3282(17)30031-5. doi: 10.1016/j.bone.2017.01.031. [Epub ahead of print] PMID: 28132909, Bone, 2017
  • Zhang, M., Zhao, L., Zhou, Y., Badr, R., Watson, P., Ye, A., Zhou, B., Zhang, J., Deng, H., Recker, R., Lappe., J. SNP rs11185644 of RXRA gene is identified for dose-response variability to vitamin D3 supplementation:a randomized clinical trial. Scientific Reports . Jan 12;7:40593. doi: 10.1038/srep40593. PMID: 28079136 PMCID: PMC5228186, Scientific Reports, 2017
  • Binkley, N., Coursin, D., Krueger, D., Iglar, P., Heiner, J., Illgen, R., Squire, M., Lappe, J., Watson, P., Hogan, K. Surgery Alters Parameters of Vitamin D Status and Other Laboratory Results. Osteoporos Int. 2016 Nov 8. [Epub ahead of print] PMID: 27826645 DOI: 10.1007/s00198-016-3819-9, Osteoporosis International, 2016
  • Bilek, L., Waltman, N., Lappe, J., Kupzyk, K.,Mack, L., Cullen, D., Berg, K., Langel, M., Meisinger, M., Portelli-Trinidad, A., Lang, M., Protocol for a randomized controlled trial to compare bone-loading exercises with risedronate for preventing bone loss in osteopenic postmenopausal women. doi:10.1186/s12905-016-0339-x PMID 27576310 PMCID 5004254, BMC Womens Health, 1(59), 2016
  • Recker, R., Lappe, J. In Memoriam: Robert P Heaney, M.D. J Bone Miner Res. 2016 Aug 20. doi: 10.1002/jbmr.2981. [Epub ahead of print] PMID: 27543924, J Bone Miner Res, 2016
  • Weaver, C., Gordon, C., Janz, K., Kalkwarf, H., Lappe, J., Lewis, R., O’Karma, M., Wallace, T., Zemel, B. (2016) Lifestyle Factors That Affect Peak Bone Mass Accrual: A Summary From a Recent Systematic Review by the National Osteoporosis Foundation. In Nutritional Influences on Bone Health – 9th International Symposium. Editors): Connie M. Weaver, Robin M. Daly, Heike A. Bischoff-Ferrari. Springer-Verlag, London., Springer Vertag, London, 293-315, 2016
  • McCormack, S., Chesi, A., Mitchell, J., Roy, S., Kalkwarf, H, Lappe, J., Gilsanz, V., Oberfield, S., Shepherd, J., Mahboubi, S., Winer, K., Kelly, A., Grant, S., Zemel, B. Skeletal maturation and population ancestry in non-obese children and adolescents. J Bone Miner Res. 2016 Jul 15. doi: 10.1002/jbmr.2914. [Epub ahead of print], J Bone Miner Res, 2016
  • Mitchell, J., Chesi, A., Elci, O., McCormack, S., Roy, S., Kalkwarf, H., Lappe, J., Gilsanz, V., Oberfield, S., Shepherd, J., Kelly, A., Grant, S., Zemel, B. The benefits of physical activity on bone density in childhood is dependent on genetic variation at known bone density loci. J Bone Miner Res. 2016 Aug;31(8):1504-12. doi: 10.1002/jbmr.2872. PMID: 27172274, J Bone Miner Res, 31(8), 1504-12, 2016
  • McDonnell, S., Baggerly, C., French, C., Baggerly, L., Garland, C., Gorham, E., Lappe, J., Heaney, R. Serum 25-Hydroxyvitamin D Concentrations ≥40 ng/ml are Associated with >65% Lower Cancer Risk: Pooled Analysis of Randomized Trial and Prospective Cohort Study. PLoS One, 2016 Apr 6;11(4):e0152441. PMID: 27049526., PLoS One, 11(4), e0152441, 2016
  • Mitchell, J., Chesi, A., McCormack, S., Roy, S., Sousminer, D., Kalkwarf, H., Lappe, J., Gilsanz, V., Oberfield, S., Shepherd, J., Kelly, A., Zemel, B., Grant, S. Rare EN1 varients and pediatric bone mass. J Bone Miner Res 2016 Mar 11 [Epub ahead of print]. PMID: 26970088., J Bone Miner Res, 2016
  • Weaver, C., Gordon, C., Janz, K., Kalkwarf, H., Lappe, J., Lewis, R., O’Karma, M., Wallace, T., Zemel, B. The National Osteoporosis Foundation's position statement on peak bone mass development and lifestyle factors: a systematic review and implementation recommendations. Osteoporos Int, 2016 Feb 8. [Epub ahead of print]. PMID: 26856587, Osteoporosis International, 2016
  • Wallace, T., Bauer, D., Gagel, R., Greenspan, S., Lappe, J., LeBoff, M., Recker, R., Saag, K., Singer, A. The National Osteoporosis Foundation’s methods and processes for developing position statements. Osteoporos Int,2016 Dec;11(1):22. doi: 10.1007/s11657-016-0276-1. Epub 2016 May 26. PMID: 27229335, Osteoporosis International, 11(1), 22, 2015
  • Boskey, A., Recker, R., Boskey, E., Lappe, J., Ma, Y., Zhang, W., Spevak, M., Watson, P. Examining the Relationships between Bone Tissue Composition, Compositional Heterogeneity and Fragility Fracture: A Matched Case Controlled FTIRI Study. J Bone Miner Res. 2015 Dec 9 2015 [Epub ahead of print]. PMID: 26636271., J Bone Miner Res, 2015
  • Medina-Gomez, C., Chesi, A., Heppe, D., Zemel, B., Yin, J., Kalkwarf, H., Hofman, A., Lappe, J., Kelly, A., Kayser, M., Oberfield, S., Gilsanz, V., Uitterlinden, A., Shepherd, J., Jaddoe, V., Grant, S., Lao, O., Rivadeneira, F. BMD Loci Contribute to Ethnic And Developmental Differences in Skeletal Fragility Across Populations: Assessment of Evolutionary Selection Pressures. (2015). Mol Biol Evol 32(11):2961-2972. PMID: 26226985. PMCID: PMC4651235., Molecular Biology and Evolution, 32(11), 2961-2972, 2015
  • Armas, L., Lappe, J., Boyce, M., Byrne, M., Inagaki, A., Cheng, S., Malik, D., Mordeson, J. (2015). Risk of falling in older women II. New Mathematics and Natural Computation 11(3):1-12., New Mathematics & Natural Computation, 11(3), 1-12, 2015
  • Cohen, A., Kamanda-Kosseh, M., Recker, R., Lappe, J., Dempster, D., Zhou, H., Cremers, S., Bucovsky, M., Stubby, J., Shane, E. Bone Density after Teriparatide Discontinuation in Premenopausal Idiopathic Osteoporosis. 2015. J Clin Endocrinol Metab 100(11):4208-4214. PMID: 26358172., Journal of Clinical Endocrinology & Metabolism, 100(11), 4208-4214, 2015
  • Mitchell, J., Zemel, B., Grant, S., Chesi, A., Elci, O., McCormack, S., Roy, S., Kelly, A., Kalkwarf, H., Lappe, J., Gilsanz, V., Oberfield, S., Shepherd, J. Genetic risk scores implicated in adult bone fragility associate with pediatric bone density. J Bone Miner Res, 2015 November 17[Epub ahead of print]. PMID: 26572781., Journal of Bone and Miner Research, 2015
  • Felix, JF., Bradfield, JP., Monnereau, C., van der Valk, RJ., Stergiakouli, E., Chesi, A., Gaillard, R., Feenstra, B., Thiering, E., Kreiner-Møller, E., Mahajan, A., Pitkänen, N., Joro, R., Cavadino, A., Huikari, V., Franks, S., Groen-Blokhuis, MM., Cousminer, DL., Marsh, JA., Lehtimäki, T., Curtin, JA., Vioque, J., Ahluwalia, TS., Myhre, R., Price, TS., Vilor-Tejedor, N., Yengo, L., Grarup, N., Ntalla, I., Ang, W., Atalay, M., Bisgaard, H., Blakemore, AI., Bonnefond, A., Carstensen, L.; Bone Mineral Density in Childhood Study (BMDCS) Consortium; Early Genetics and Lifecourse Epidemiology (EAGLE) consortium, Eriksson, J., Flexeder, C., Franke, L., Geller, F., Geserick, M., Hartikainen, AL., Haworth, CM., Hirschhorn, JN., Hofman, A., Holm, JC., Horikoshi, M., Hottenga, JJ., Huang, J., Kadarmideen, HN., Kähönen, M., Kiess, W., Lakka, HM., Lakka, TA., Lewin, AM., Liang, L., Lyytikäinen, LP., Ma, B., Magnus, P., McCormack, SE., McMahon, G., Mentch, FD., Middeldorp, CM., Murray, CS., Pahkala, K., Pers, TH., Pfäffle, R., Postma, DS., Power, C., Simpson, A., Sengpiel, V., Tiesler, CM., Torrent, M., Uitterlinden, AG., van Meurs, JB., Vinding, R., Waage, J., Wardle, J., Zeggini, E., Zemel, BS., Dedoussis, GV., Pedersen, O., Froguel, P., Sunyer, J., Plomin, R., Jacobsson, B., Hansen, T., Gonzalez, JR., Custovic, A., Raitakari, OT., Pennell, CE., Widén, E., Boomsma, DI., Koppelman, GH., Sebert, S., Järvelin, MR., Hyppönen, E., McCarthy, MI., Lindi, V., Harri, N., Körner, A., Bønnelykke, K., Heinrich, J., Melbye, M., Rivadeneira, F., Hakonarson, H., Ring, SM., Smith, GD., Sørensen, TI., Timpson, NJ., Grant, SF., Jaddoe, VW; Early Growth Genetics (EGG) Consortium; Bone Mineral Density in Childhood Study BMDCS Consortium. Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index. Hum Mol Genet 2015 Nov 24.[Epub ahead of print] PMID: 26604143., Human Molecular Genetics, 2015
  • Cohen, A., Shen, W., Dempster, D., Zhou, H., Recker, R., Lappe, J., Kepley, A., Kamanda-Kosseh, M., Bucovsky, M., Stein, E., Nickolas, T., Shane, E. (2015). Marrow adiposity assessed on transiliac crest biopsy samples correlates with noninvasive measurement of marrow adiposity by magnetic resonance spectroscopy (1H-MRS) at the spine but not the femur. Osteoporos Int 26(10):2471-2478. PMID: 25986383., Osteoporosis International, 26(10), 2471-2478, 2015
  • Lappe, J. and Binkley, N. Vitamin D and Sarcopenia/Falls. (2015). J Clin Densitom 18(4):478-482. PMID: 26059567., Journal of Clinical Densitometry, 18(4), 478-482, 2015
  • Weaver, C., Alexander, D., Boushey, C., Dawson-Hughes, B., Lappe, J., LeBoff, M., Liu, S., Looker, A., Wallace, T., Wang, D. Calcium plus vitamin D supplementation and risk of fractures: An updated meta-analysis from the National Osteoporosis Foundation. Osteoporos Int 2015 October 28 [Epub ahead of print]. PMID: 26510847., Osteoporosis International, 2015
  • Xie, B., Avila, J., Ng, B., Fan, B., Loo, V., Gilsanz, V., Hangartner, T., Kalkwarf, H., Lappe, J., Oberfield, S., Winer, K., Zemel, B., Shepherd, J. Accurate body composition measures from simple whole body silhouettes. Med Phys Aug;42(8):4668-4677. PMID: 26233194. PMCID: PMC4506301., Medical Physics, 42(8), 4668-4677, 2015
  • Ascenzi, MG., Chin, J., Lappe, J., Recker, R. Non-osteoporotic women with low-trauma fracture present altered birefringence in cortical bone. (2015). Bone. S8756-3282(15)00381-00386. PMID: 26514952, Bone, S8756-3282(15), 381-386, 2015
  • Mitchell, J., Chesi, A., Elci, O., McCormack, S., Kalkwarf, H., Lappe, J., Gilsanz, V., Oberfield, S., Shepherd, J., Kelly, A., Zemel, B., Grant, S. (2015). Genetics of bone mass in childhood and adolescence: effects of sex and maturation interactions. J Bone Miner Res 30(9):1676-1683. PMID: 25762182., Journal of Bone and Miner Research, 30(9), 1676-1683, 2015
  • Chesi, A., Mitchell, J., Kalkwarf, H., Bradfield, J., Lappe, J., McCormack, S., Gilsanz, V., Oberfield, S., Hakonarson, H., Shepherd, J., Kelly, A., Zemel, B., Grant, S. (2015). A Trans-ethnic Genome-wide Association Study Identifies Gender Specific Loci Influencing Pediatric aBMD and BMC at the Distal Radius. Hum Mol Genet 24(17):5053-5059. PMID: 26041818., Human Molecular Genetics, 24(17), 5053-5059, 2015
  • Binkley, N., Lappe, J., Singh, R., Khosla, S., Krueger, D., Drezner, M., Blank, R. (2015). Can vitamin D metabolite measurements facilitate a “Treat to Target” paradigm to guide vitamin D supplementation? Osteoporos Int 26(5):1655-1660. PMID: 25572049., Osteoporosis International, 26(5), 1655-1660, 2015
  • Ollberding, N., Gilsanz, V., Lappe, J., Oberfield, S., Shepherd, J., Winer, K., Zemel, B., Kalkwarf, H. (2015). Reproducibility and intermethod reliability of a calcium food frequency questionnaire for use in Hispanic, non-Hispanic Black, and non-Hispanic White youth. J Acad Nutr Die 115(4):519-527. PMID: 25683819. PMCID: PMC4380535., Journal of the Academy of Nutrition and Dietetics, 115(4), 519-527, 2015
  • Short, D., Gilsanz, V., Kalkwarf, H., Lappe, J., Oberfield, S., Shepherd, J., Winer, K., Zemel, B., Hangartner, T. (2015). Anthropometric Models of Bone Mineral Content and Areal Bone Mineral Density Based on the Bone Mineral Density in Childhood Study. Osteoporosis International 26(3):1099-1108. PMID: 25311106., Osteoporosis International, 26(3), 1099-1108, 2015
  • Lewis, J., Ivey, K., Radavelli-Bagatini, S., Rejnmark, L., Chen, C., Simpson, J., Lappe, J., Mosekilde, L., Prenteci, R., Prince, R. (2015). Response to "Calcium supplements increase risk of myocardial infarction". J Bone Miner Res 30(2):391-392. PMID: 25413937., Journal of Bone and Miner Research, 30(2), 391-392, 2015
  • Grant, W., Wimalawansa, S., Holick, M., Cannell, J., Pludowski, P., Lappe, J., Pittaway, M., May P. (2015). The Vitamin D Task Force on Optimal Usage of Vitamin D for Adults with Medically Complex Developmental Disabilities. AADMD position statement: Considerations on vitamin D, emphasizing the health benefits for those with neurodevelopmental disorders and intellectual disabilities. Nutrients 7(3):1538-1564. PMID: 25734565., Nutrients, 7(3), 1538-1564, 2015
  • Lewis, J., Ivey, K., Radavelli-Bagatini, S., Rejnmark, L., Chen, C., Simpson, J., Lappe, J., Mosekilde, L., Prenteci, R., Prince, R. (2015). The effects of calcium supplementation on coronary heart disease hospitalization and death in postmenopausal women: A collaborative meta-analysis of randomized controlled trials. J Bone Miner Res Jan;30(1):165-175. PMID: 25042841., Journal of Bone and Miner Research, 30(1), 165-175, 2015
  • Lappe, J., Watson, P., Gilsanz, V., Hangartner, T., Kalkwarf, H., Oberfield, S., Shepherd, J., Winer, K., Zemel, B. (2015). The longitudinal effects of physical activity and dietary calcium on bone mass accrual across stages of pubertal development. J Bone Miner Res Jan 30(1):156-164. PMID: 25130421., Journal of Bone and Miner Research, 30(1), 156-164, 2015
  • Armas, L., Lappe, J., Slavik, V., Slattery, K., Cheng, S., Malik, D., Mordeson, J. (2015). Risk of falling in older women. New Mathematics and Natural Computation 11(1):1-12., New Mathematics & Natural Computation, 11(1), 1-12, 2015
  • Zhou, Y., Zhao, L-J., Xu, X., Ye, A., Travers-Gustafson, D., Zhou, B., Wang, H-W., Hamm, L., Deng, H-W., Recker, R., Lappe, J. (2014). DNA methylation levels of CYP2R1 and CYP24A1 predict vitamin D response variation. J Steroid Biochem Mol Biol; Oct;144 Pt A:207-217. PMID: 24128439. PMCID: PMC3984616., Journal of Steroid Biochemistry and Molecular Biology, 144(PtA), 207-217, 2014
  • Nishiyama, K., Cohen, A., Young, P., Wang, J., Lappe, J., Guo, X., Dempster, D., Recker, R., Shane, E. (2014). Teriparatide increases strength of the peripheral skeleton in premenopausal women with idiopathic osteoporosis: A pilot HR-pQCT study. J Clin Endocrinol Metab, Jul;99(7):2418-2425. PMID: 24684466. PMCID: PMC4079304., Journal of Clinical Endocrinology & Metabolism, 99(7), 2418-2425, 2014
  • Kelly, A., Winer, K., Kalkwarf, H., Oberfield, S., Lappe, J., Gilsanz, V Zemel, B. (2014). Age-based reference ranges for annual height velocity in U.S. children. J Clin Endocrinol Metab Jun;99(6):2104-2112. PMID: 24601728. PMCID: PMC4037731., Journal of Clinical Endocrinology & Metabolism, 99(6), 2104-2112, 2014
  • Wren, T., Kalkwarf, H., Zemel, B., Lappe, J., Oberfield, S., Shepherd, J., Winer, K., Gilsanz, V. (2014). Longitudinal Tracking of DXA Bone Measures Over 6 years in Children and Adolescents: Persistence of Low Bone Mass to Maturity. The Journal of Pediatrics Jun;164:1280-1285. PMID: 24485819. PMCID: PMC4035430., Journal of Pediatrics, 164, 1280-1285, 2014
  • Cao, Z., Moore, B., Wang, Y., Peng, X., Lappe, J., Recker, R., Xiao, P. (2014). MiR-422a as a potential cellular microRNA biomarker for postmenopausal osteoporosis. PloS One May 12;9(5):e97098. PMID: 24820117. PMCID: PMC4018259., PLoS One, 12;9(5), e97098, 2014
  • Zhou, Q-H., Zhao, L-J., Wang,P., Badr, R., X, X-J., Bu, F-X., Lappe, J., Recker, R., Zhou, Y., Ye, A., Zhou, B-T. 2014. Comprehensive analysis of the association of EGFR, CALM3 and SMARCD1 gene polymorphisms with BMD in Caucasian women. PLoS One Nov 14;9(11):e112358. PMID: 25396734. PMCID: PMC4232396, PLoS One, 149(11), e112358, 2014
  • Misof, B., Dempster, D., Zhou, H., Roschger, P., Fratzl-Zelman, N., Fratzl, P., Silverberg, S., Shane, E., Cohen, A., Stein, E., Nickolas, T., Recker, R., Lappe, J., Bilezikian, J., Klaushofer, K. (2014). Relationship of bone mineralization density distribution (BMDD) in cortical and cancellous bone within the iliac crest of healthy premenopausal women. Calcif Tissue Int Oct;95(4):332-339. PMID: 25134800., Cacified Tissue International, 95(4), 332-339, 2014
  • Cohen, A., Dempster, DW., Recker, RR., Lappe, JM., Zhou, H., Zwahlen, A., Muller, R., Zhao, B., Guo, X., Lang, T., Saeed, I., Liu, XS., Guo, XE., Cremers, S., Rosen, CJ., Stein, EM., Nickolas, TL., McMahon, DJ., Young, P., Shane, E. (2013). Abdominal fat is associated with lower bone formation and inferior bone quality in healthy premenopausal women: a transiliac bone biopsy study. J Clin Endocrinol Metab 98(6): 2562-2572. PMID: 23515452. PMCID: PMC3667251., Journal of Clinical Endocrinology & Metabolism, 98(6), 2562-2572, 2013
  • Cohen, A., Stein, EM., Recker, RR., Lappe, JM., Dempster, DW., Zhou, H., Cremers, S., McMahon, DJ., Nickolas, TL., Muller, R., Zwahlen, A., Young, P., Stubby, J., Shane, E. (2013). Teriparatide for Idiopathic Osteoporosis in Premenopausal Women: A Pilot Study. J Clin Endocrinol Metab 98(5):1971-1981. PMID: 23543660. PMCID: PMC3644608., Journal of Clinical Endocrinology & Metabolism, 98(5), 1971-1981, 2013
  • Lappe, J., Kunz, I., Bendik, I., Weber, P., Duesterloh, A., Recker, R., Heaney, R. (2013). Effect of a combination of genistein, polyunsaturated fatty acids and Vitamins D3 and K1on bone mineral density in postmenopausal women: a randomized, placebo-controlled, double-blind pilot study. Eur J Nutr 52(1):203-215. PMID: 22302614. PMCID: PMC3549413., European Journal of Nutrition, 52(1), 203-215, 2013
  • Misof, BM., Gamsjaeger, S., Cohen, A., Hofstetter, B., Roschger, P., Stein, E., Nickolas, TL., Rogers, HF., Dempster, D., Zhou, H., Recker, R., Lappe, J., McMahon, D., Paschalis, E., Fratzl, P., Shane, E., Klaushofer, K. (2012). Bone material properties in premenopausal women with idiopathic osteoporosis. J Bone Miner Res July 6. [epub ahead of print]. PMID: 22777919., Journal of Bone and Miner Research, 27(12), 2551-2561, 2012
  • Cohen, A., Recker, R., Lappe, J., Dempster, D., Cremers, S., McMahon, D., Stein, E., Fleischer, J., Rosen, C., Rogers, H., Staron, R., Lemaster, J., Shane, E. Premenopausal women with idiopathic low-trauma fractures and/or low bone mineral density. PMID: 21365462., Osteoporosis International, 23, 171-182, 2012
  • Wren, T., Shepherd, J., Kalkwarf, H., Zemel, B., Lappe, J., Oberfield, S., Dorey, F., Winer, K., Gilsanz, V. Racial disparity in fracture risk between White and Non-White children in the United States PMID: 22974572., Journal of Pediatrics, 161, 1035-1040, 2012
  • Hanson, C., Anderson-Berry, A., Lyden, E., Rafferty, K., Armas, L., Elliott, E., Dudley, E., Lappe, J. (2012). Intake of key pregnancy nutrients in midwest adolescents of child-bearing potential: Vitamin D, polysaturated fatty acids, and folate. ICAN 4(6):355-360, Institute for Career Advancement (ICAN), 4(6), 355-360, 2012
  • Cohen, A., Lang, T., McMahon, D., Liu, X., Guo, X., Zhang, C., Stein, E., Dempster, D., Young, P., Saeed, I., Lappe, J., Recker, R., Shane, E. (2012). Central QCT reveals lower volumetric BMD and stiffness in premenopausal women with idiopathic osteoporosis, regardless of fracture history. J Clin Endocrinol Metab 97(11):4244-4252. PMID: 22962425., Journal of Clinical Endocrinology & Metabolism, 97(11), 4244-4252, 2012
  • Cohen, A., Dempster, D., Stein, E., Nickolas, T., Zhou, H., McMahon, D., Muller R., Kohler, T., Zwahlen, A., Lappe, J., Chen, P., Recker, R., Shane, E. (2012). Increased marrow adipocity in premenopausal women with idiopathic osteoporosis. J Clin Endocrinol Metab 97(8):2782-2791. PMID: 22701013., Journal of Clinical Endocrinology & Metabolism, 97(8), 2782-2791, 2012
  • Zhao, LJ., Zhou, Y., Bu, F., Travers-Gustafson, D., Ye, A., Xu, X., Hamm, L., Gorsage, DM., Fang, X., Deng, HW., Recker, RR., Lappe, JM. (2012). Factors predicting vitamin D response variation in non-Hispanic white postmenopausal women. J Clin Endocrinol Metab 97(8):2699. PMID: 22585090., Journal of Clinical Endocrinology & Metabolism, 97(8), 2699, 2012
  • Ma, D., Li, Y., Hackfort, B., Zhao, Y., Xiao, J., Swanson, PC., Lappe, J., Xiao, P., Cullen, D., Akhter, M., Recker, R., Xiao, GG. (2012). Smoke-induced signal molecules in bone marrow cells from altered low-density lipoprotein receptor-related protein 5 mice. J Proteome Res 11(7):3548-3560. PMID: 22616666., Journal of Proteome Research, 11(7), 3548-3560, 2012
  • Wang, Y., Li, L., Moore, BT., Peng, X-H., Fang, X., Lappe, J., Recker, R., Xiao, P. (2012). MiR-133a in Human Circulating Monocytes: A Potential Biomarker Associated with Postmenopausal Osteoporosis. PLoS ONE 7(4):e34641. PMID: 22506038. PMCID: PMC3323546., PLoS One, 7(4), e34641, 2012
  • Lappe, J., Heaney R. (2012) Why Randomized Controlled Trials of Calcium and Vitamin D Sometimes Fail. J Dermato-Endocrinology 4(2):1-6. PMID: 22928064. PMCID: PMC3427206., Journal of Dermato-Endocrinology, 4(2), 1-6, 2012
  • Zhao, Y., Cao, R., Ma, D., Zhang, H., Lappe, J., Recker, R., Xiao, G. (2011). Efficacy of calcium supplementation for human bone health by mass spectrometry profiling and cathepsin K measure ment in plasma samples. J Bone Miner Metab 29(5):552-560. PMID: 21213114., Journal of Bone and Miner Research, 29(5), 552-560, 2011
  • Rafferty, K., Lappe, J. Watson, P. (2010) The selection and prevalence of natural and fortified calcium food sources in the diets of adolescent girls. J Nutr Educ Behav 43(2):96-102. PMID: 21392712. PMCID: PMC3056143., Journal of American of the Dietetic Association, 43(2), 96-102, 2011
  • Jepsen, K., Centi, A., Duarte, GF., Galloway, K., Goldman, H., Hampson, N., Lappe, JM., Cullen, DM., Greeves, J., Izard, R., Nindl, BC., Kraemer, WJ., Negus, CH., Evans, RK. Biological constraints that limit compensation of common skeletal trait variant lead to inequivalence of tibial function among healthy young adults. PMID: 21898595., Journal of Bone and Miner Research, 26, 2872-2885, 2011
  • Shepherd, J., Wang, L., Fan, B., Gilsanz, V.,. Kalkwarf, H, Lappe, J., Lu, Y., Hangartner, T., Zemel, B., Fredrick, M., Oberfield, S., Winer, K. Optimal Monitoring Time Interval Between DXA Measures in Children. PMID: 21773995. PMCID: PMC3200454., Journal of Bone and Miner Research, 26(11), 2745-2752, 2011
  • Burgi A, Gorham E, Garland C, Mohr S, Garland F, Thompson K, Lappe J. (2011). High Serum 25-hydroxyvitamin D is associated with low incidence of stress fractures. PMID: 21698667., Journal of Bone and Miner Research, 26(4), 2371-2377, 2011
  • Pilz S, Tomaschitz A, März W, Drechsler C, Ritz E, Zittermann A, Cavalier E, Pieber TR, Lappe JM, Grant WB, Holick MF, Dekker JM. Vitamin D, cardiovascular disease and mortality PMID: 21682758., Clinical Endocrinology (Oxford), 75 (5), 575-584, 2011
  • Cohen, A., Dempster, D., Recker, R., Stein, E., Lappe, J., Zhou, H., Wirth, A., van Lenthe, G., Kohler, T., Zwahlen, A., Muller, R., Rosen, C., Cremers, S., Nickolas, T., McMahon, D., Rogers, H., Staron, R., LeMaster, J., Shane, E. Abnormal bone microarchitecture and evidence of osteoblast dysfunction in premenopausal women with idiopathic osteoporosis. PMID: 21832117., Journal of Clinical Endocrinology & Metabolism, 96(10), 3095-3105, 2011
  • Zhang, H., Lu, W., Rui R., Zhao, Y., Xiao, J., Gu, W., Deng, C., Miao, D., Lappe, J., Recker, R., Guishan, G. Adipocytes derived from human bone marrow mesenchymal stem cells exert inhibitory effects on osteoblastogenesis. PMID: 21663588., Current Molecular Medicine, 11(6), 489-502, 2011
  • Lappe J. The role of vitamin D in human health: A paradigm shift., Journal of Evidence-Based Complementary & Alternative Medicine, 16, 58-72, 2011
  • Rafferty K, Heaney JB, Lappe JM. Dietary calcium intake is a marker for total diet quality in adolescent girls and women across the life-cycle., Nutrition Today, 46, 244-251, 2011
  • Rafferty, K., Watson, P., Lappe, J. The Selection and Prevalence of Natural and Fortified Food Sources in the Diets of Adolescent Girls. PMID: 21392712. PMCID: PMC3056143., Journal of Nutrition Education and Behavior, 43(2), 96-102, 2011
  • Short, D., Zemel, B., Gilsanz, V., Kalkwarf, H., Lappe, J., Mahboubi, S., Oberfield, S., Shepherd, J., Winer, K, Hangartner, T. Fitting of Bone Mineral Density with Consideration of Anthropometric Parameters. PMID: 20495903. PMCID: PMC2996478, Osteoporosis International, 22(4), 1047-1057, 2011
  • Gilsanz V, Chalfant J, Kalkwarf H, Zemel B, Lappe J, Oberfield S, et al. Age at onset of puberty predicts bone mass in young adulthood. PMID: 20797727., Journal of Pediatrics, 158(1), 100-105, 105.e1-2, 2011
  • Bu, F., Armas, L., Lappe, J., Gao, G., Recker, R., Zhao L. Comprehensive Association Analysis of Nine Candidate Genes with Serum 25-Hydroxy Vitamin D Levels among Healthy Caucasian Subjects. PMID: 20809279., Human Genetics, 128(5), 549-556, 2010
  • Liu, X., Cohen, A., Shane, E., Yin, P., Stein, E., Rogers, H., Kokolus, S., McMahon, D., Lappe, J., Recker, R., Lang, T., Guo, X. Bone Density, Geometry, Microstructure and Stiffness: Relationships Between Peripheral and Central Skeletal Sites Assessed by DXA, HR-pQCT, and cQCT in Premenopausal Women. PMID: 20499344. PMCID: PMC3128822., Journal of Bone and Miner Research, 25(10), 2229-2238, 2010
  • Souberbielle, J., Body, J., Lappe, J., Plebani, M., Shoenfeld, Y., Wang, T., Bischoff-Farrari, H., Cavalier, E., Ebeling, P., Fardellone, P., Gandini, S., Gruson, D., Guerin, A.P., Heickendorff, L., Hollis, B., Ish-Shalom, S., Jean, G., von Landenberg, P., Largura, A., Olsson, T., Pierrot-Deseilligny, C., Pilz, S., Tincani, A., Valcour, A., Zittermann, A. Vitamin D and musculoskeletal health, cardiovascular disease, autoimmunity and cancer: Recommendations for clinical practice. PMID: 20601202., Autoimmunity Reviews, 9(11), 709-715, 2010
  • Heaney, R., Recker, R., Watson, P., Lappe, J. Phosphate and carbonate salts of calcium support robust bone building in osteoporosis. PMID: 20484446. PMCID: PMC2884321, American Journal of Clinical Nutrition, 92(1), 101-105, 2010
  • Liu, X., Cohen, A., Shane, E., Stein, E., Rogers, H., Kokolus, S., Yin, P., McMahon, D., Lappe, J., Recker, R., Guo, X. Individual Trabeculae Segmentation (ITS)-Based Morphological Analyses of High Resolution Peripheral Quantitative Computed Tomography Images Detects Abnormal Trabecular Plate and Rod Microarchitecture in Premenopausal Women with Idiopathic Osteoporosis.PMID: 20200967. PMCID: PMC3131618., Journal of Bone and Miner Research, 25(7), 1496-1505, 2010
  • Zhou, J., Zhao, L., Watson, P., Zhang, Q., Lappe, J. The effect of calcium and vitamin D supplementation on obesity in postmenopausal women: secondary analysis for a large-scale, placebo controlled, double-blind, 4-year longitudinal clinical trial. PMID: 20650013. PMCID: PMC3161354., Nutrition & Metabolism, 7, 62-70, 2010
  • Kalkwarf, H., Gilsanz, V., Lappe, J., Oberfield, S., Shepherd, J., Hangartner, T., Huang, X., Frederick, M., Winer, K., Zemel, B. Tracking of bone mass and density during childhood and adolescence. PMID: 20194709. PMCID: PMC2853985., Journal of Clinical Endocrinology and Metabolism, 95(4), 1690-1698, 2010
  • Osborne, D. L., Lappe, J. M., Cullen, D. M., Watson, P. A. Assessing longitudinal growth in bone density in females at the heel using ultrasound, American Journal of Human Biology, 22, 266-266, 2010
  • Zhang, H., Cao, R., Lee, P., Deng, C., Zhao, Y., Lappe, J., Recker, R., Yen, Y., Qi, W., Tsai, M-Y., Go, V., Xiao, G. Inhibition of protein phosphorylation in MIA pancreatic cancer cells: Confluence of metabolic and signaling pathways. PMID: 20035555. PMCID: PMC2836017., Journal of Proteome Research, 9(2), 980-989, 2010
  • Cohen, A., Dempster, D., Mueller, R., Guo, X., Nickolas, T., Liu, X., Zhang, X., Wirth, A., van Lenthe, G., Kohler, T., McMahon, D., Zhou, H., Rubin, M., Bilezikian, J., Lappe, J., Recker, R., Shane, E. Assessment of Trabecular and Cortical Architecture and Mechanical Competence of Bone by High-Resolution Peripheral Computed Tomography: Comparison with Transiliac Bone Biopsy. PMID: 19455271. PMCID: PMC2908272., Osteoporosis International, 21(2), 263-273, 2010
  • Cohen A., Liu X., McMahon D., Rogers H., LeMaster J., Recker R., Lappe J., Guo X., Shane E. Bone microarchitecture and stiffness in premenopausal women with osteoporosis. J Clin Endocrinol Metab PMID: 19837923. PMCID: PMC2775661., Journal of Clinical Endocrinology & Metabolism, 94(11), 4351-4360, 2009

Publications

  • McCormack, S., Cousminer, D., Chesi, A., Mitchell, J., Roy, S., Kalkwarf, H., Lappe, J., Gilsanz, V., Oberfield, S., Shepherd, J., Winer, K., Kelly, A., Grant, S., Zemel, B. Association between linear growth and bone accrual: a longitudinal assessment of a diverse cohort of children and adolescents. In Press JAMA Pediatrics January 2017, JAMA, 2017

Presentations

  • Mitchell, J., Chesi, A., McCormack, S., Cousminer, D., Kalkwarf, H., Lappe, J., Gilsanz, V.,
    Oberfield, S., Shepherd, J., Kelly, A., Zemel, B., and Grant, S.  Established Adult Height Loci Operate in the Pediatric Setting to Influence Bone Mineral Density. Poster Presentation ASBMR 2017 Annual Meeting, September 8-11, 2017 Denver, Colorado, USA., 2017
  • Cohen, A., Dempster, D., Zhou, H., Recker, R., Lappe, J., Kamanda-Kosseh, M., Bucovsky, M.,
    RoyChoudhury, A., Stubby, J., Stein, E., Nickolas, T., Shane, E. Quadruple-Labeled Transiliac Crest Biopsies Quantify Bone Formation Response to Teriparatide in Premenopausal Women with Idiopathic Osteoporosis. Poster Presentation ASBMR 2017 Annual Meeting, September 8-11, 2017 Denver, Colorado, USA., 2017
  • Cousiminer, D., Chesi, A., Mitchell, J., Kalkwarf, H., Lappe, J. Gilsanz, V., Oberfield, S.,
    Shepherd, J., Kelly, A., McCormack, S., Voight, B., Zemel, B., Grant, S. Longitudinal genome-wide association analysis and heritability estimates of pediatric bone mineral density. Poster Presentation ASBMR 2017 Annual Meeting, September 8-11, 2017 Denver, Colorado, USA., 2017
  • Chesi, A., Grant, S., Zemel, B., McCormack, S., Cousminer, D., Mitchell, J., Kelly, A.,
    Rivadeneira, F., Medina-Gomez, C., Grgic, O., Kalkwarf, H., Lappe, J., Shepherd, J., Gilsanz, V., Oberfield, S., Mahboubi, S., Jaddoe, V., Trajanoska, K., Uitterlinden, A., Wolvius, E.  A genome-wide association meta-analysis implicates adrenal steroidogenesis in the process of skeletal maturation. Oral Presentation ASBMR 2017 Annual Meeting, September 8-11, 2017 Denver, Colorado, USA, 2017
  • Mitchell, J., Chesi, A., McCormack, S., Cousminer, D., Kalkwarf, H., Lappe, J., Gilsanz, V., Oberfield, S., Shepherd, J., Kelly, A., Zemel, B., Grant, S. Principal Components Derived Bone Density Phenotypes and Genetic Regulation of the Pediatric Skeleton. Oral presentation Bone Research Society Annual Meeting, Bristol, UK June 25-27, 2017, 2017
  • Mitchell, J., Chesi, A., McCormack, S., Cousminer, D., Kalkwarf, H., Lappe, J., Gilsanz, V., Oberfield, S., Shepherd, J., Kelly, A., Zemel, B., Grant, S. Principal Components Derived Bone Density Phenotypes and Genetic Regulation of the Pediatric Skeleton. Oral presentation to 8th International Conference on Children’s Bone Health, Wurzberg, Germany June 10-13, 2017, 2017
  • Mitchell, J., Cousminer, D., Chesi, A., McCormack, S., Kalkwarf, H., Lappe, J., Gilsanz, V., Oberfield, S., Shepherd, J., Kelly, A., Grant, S. High and Low Impact Physical Activity Substitution and Pediatric Bone Density. Poster Presentation accepted at 2017 Annual Meeting, World Congress on Exercise is Medicine, and World Congress on the Basic Science of Exercise and the Brain of the American College of Sports Medicine, Denver, CO May 31, 2017, 2017
  • Cousmine, D., Mitchell, J., Chesi, A., Roy, S. , Kalkwarf, H., Lappe, J., Gilsanz, V., Oberfield, S., Shepherd, J., Kelly, A., McCormack, S., Voight, B.,  Zemel, B., Grant, S. Genetically determined later puberty impacts lowered bone mineral density in childhood and adulthood. Developmental Origins of Health and Disease (DOHaD) Rotterdam, The Netherlands, Oct 15-17, 2017, 2017
  • Lappe, J., Watson, P., Travers-Gustafson, D., Recker, R., Garland, C., Gorham, E., Baggerly, K., and McDonnell, S.  A Randomized Clinical Trial to Determine the Effects of Vitamin D3 and Calcium Supplementation on Cancer Incidence. Grand Rounds Oral Presentation, Creighton School of Medicine, April 26, 2017., 2017
  • Lappe, J., Watson, P., Travers-Gustafson, D., Recker, R., Garland, C., Gorham, E., Baggerly, K., and McDonnell, S.  A Randomized Clinical Trial to Determine the Effects of Vitamin D3 and Calcium Supplementation on Cancer Incidence. Oral presentation at the Vitamin D Workshop , Orlando FL, March 28 – March 31., 2017
  • Lappe, J., Travers-Gustafson, D., Garland, C., Heaney, R., Recker, R., and Watson, P. Vitamin D3 and calcium supplementation significantly decreases cancer risk in older women. Oral presentation presented as a late-breaking abstract at the American Public Health Association Annual meeting , Denver, CO, October 29 – November 2, 2016, 2016
  • Evans, D., Alliston, T., Zhang, B., Youngren, J., Recker, R., Lappe, J., Reppe, S., Lang, T. Genetic Prediction of Incident Fracture Due to Bone Quality Deficit. Poster presentation at ASBMR, Atlanta, GA, September 16-19, 2016., 2016
  • Chesi, A., Mitchell, J., Kalkwarf, H., Bradfield, J., Lappe, J., McCormack, S., Gilsanz, V., Oberfield, S., Hakonarson, H., Shepherd, J., Kelly, A., Zemel, B., Grant, S. A Genome-wide Association Study Identifies Gender Specific Loci Influencing a BMD and BMC at Multiple Skeletal Sites in Children of European Descent. Poster presentation at ASBMR, Atlanta, GA, September 16-19, 2016., 2016
  • Cousiminer, D., Mitchell, J., Chesi, A., Roy, S., Kalkwarf, H., Lappe, J. Gilsanz, V., Voight, B., Oberfield, S., Shepherd, J., Kelly, A., McCormack, S., Grant, S., Zemel, B. Individual Variants and Genetic Risk Score for Puberty Timing Associate with Pediatric Bone Mineral Density. Poster presentation at ASBMR, Atlanta, GA, September 16-19, 2016, 2016
  • Cousiminer, D., Chesi, A., Mitchell, J., Roy, S., Kalkwarf, H., Lappe, J. Gilsanz, V., Oberfield, S., Shepherd, J., Kelly, A., McCormack, S., Voight, B., Zemel, B., Grant, S. Heritability of Bone Mineral Density and Content in Childhood and Adolescence. Poster presentation at ASBMR, Atlanta, GA, September 16-19, 2016., 2016
  • Rizzo, S., Farlay, D., Akhter, M., Boskey, A., Recker, R., Lappe, J., Boivin, G. Variables Reflecting the Mineralization of Bone Tissue from Fracturing versus Non-fracturing Postmenopausal Women. Poster presentation at ASBMR, Atlanta, GA, September 16-19, 2016., 2016
  • Cohen, A., Kamanada-Kosseh, M., McMahon, D., Dempster, D., Zhou, H., Lappe, J., Recker, R., Stubby, J., Bucovsky, M., Shane, E. Biopsy-based bone remodeling characteristics of premenopausal women with idiopathic osteoporosis on selective serotonin reuptake inhibitors (SSRIs). Poster presentation at ASBMR, Atlanta, GA, September 16-19, 2016., 2016
  • Binkley, N., Coursin, D., Krueger, D., Iglar, P., Heiner, J., Ilgen, R., Lappe, J., Squire, M., Watson, P., Hogan, K. Surgery Alters Parameters of Vitamin D Status and Other Laboratory Results Relevant to Fracture Liaison Programs. Submitted to International Society of Clinical Densitometry, Galway, Ireland, June 1-4, 2016., 2016
  • McDonnell, S., Baggerly, C., French, C., Baggerly, L., Garland, C., Gorham, E., Lappe, J., Heaney, R. Serum 25-Hydroxyvitamin D Concentrations ≥40 ng/ml are Associated with > 65% Lower Cancer Risk: Pooled Analysis of Randomized Trial and Prospective Cohort Study. Presented to 2016 Epidemiology Research Exchange, San Diego, CA, April 29, 2016., 2016
  • Cousminer, D., Chesi, A., Mitchell, J., Roy, S., Kalkwarf, H., Lappe, J., Gilsanz, V., Voight, B., Oberfield, S., Shepherd, J., Kelly, A., McCormack, S., Zemel, B., Grant, S. Individual Variants and Genetic Risk Score for Age at Menarche Associate with Pediatric Bone Mineral Density. Presented at the 98th Annual Meeting of the Endocrine Society, Boston, MA, April 1-4, 2016., 2016
  • Cousminer, D., Chesi, A., Mitchell, J., Roy, S., Kalkwarf, H., Lappe, J., Gilsanz, V., Voight, B., Oberfield, S., Shepherd, J., Kelly, A., McCormack, S., Zemel, B., Grant, S. Individual Variants and Genetic Risk Score for Age at Menarche Associate with Pediatric Bone Mineral Density. Accepted for presentation at the Discovery to Innovation, Children’s Hospital of Philadelphia, Philadelphia, PA, Feb 24, 2016., 2016
  • Lappe, J. Boning up on osteoporosis: Promotion of Bone Health Across the Life Span. Presented at Women in Medicine and Science, Creighton University, February 11, 2016., 2016
  • Lappe, J. Calcium effects on bone accrual. Invited presentation at the National Institutes of Health Symposium on Peak Bone Mass. Washington D.C. Nov 17-18, 2015., 2015
  • Bone health in adolescents. Brownell Talbot High School. Omaha NE, 2015
  • Chesi, A., Mitchell, J., Basile, K., McCormack, S., Roy, S., Kalkwarf, H., Lappe, J., Gilsanz, V., Oberfield, S., Shepherd, J., Kelly, A., Zemel, B., Grant, S. Multiple GWAS-implicated adult height loci operate in the context of pediatric bone mineral density and content determination. Presented at the ASBMR, Seattle, WA, October 9-12, 2015., 2015
  • Marquino, L., Fan, B., Ng, B., Gilsanz, V., Kalkwarf, H., Lappe, J., Oberfield, S., Winer, K., Zemel, B., Shepherd, J. Study of Body Composition and Bone Measures Acquired from Osteoporotic Measurement Sites using Regional DXA Scans. Presented at the ASBMR, Seattle, WA, October 9-12, 2015., 2015
  • Marquino, L., Fan, B., Ng, B., Gilsanz, V., Kalkwarf, H., Lappe, J., Oberfield, S., Winer, K., Zemel, B., Shepherd, J. Study of Body Composition and Bone Measures Acquired from Osteoporotic Measurement Sites using Regional DXA Scans. Presented at the ASBMR, Seattle, WA, October 9-12, 2015., 2015
  • Cleland, T., Cohen, A., Dempster, D., Recker, R., Lappe, J., Zhou, H., Shane, E., Vashishth, D. Advanced Glycation End-products are Higher in Trabecular Bone from Premenopausal Women with Idiopathic Osteoporosis. Presented at the ASBMR, Seattle, WA, October 9-12, 2015., 2015
  • Cohen, A., Kamanda-Kosseh, M., Zhou, H., Dempster, D., Bucovsky, M., Stubby, J., Recker, R., Lappe, J., Shane, E. Pregnancy and lactation associated osteoporosis (PLO): Similar bone structure and lower bone remodeling than idiopathic osteoporosis. Presented at the ASBMR, Seattle, WA, October 9-12, 2015., 2015
  • Cohen, A., Manavalan, J., Kousteni, S., Recker, R., Lappe, J., Dempster, D., Zhou, H., McMahon, D., Bucovsky, M., Kamanda-Kosseh, M., Stubby, J., Shane, E. Circulating osteogenic progenitors (COPs) and COP surface IGF-1 receptor density predict tissue-based bone formation rate and response to teriparatide (TPTD) in premenopausal women with idiopathic osteoporosis (IOP). Presented at the ASBMR, Seattle, WA, October 9-12, 2015., 2015
  • Mitchell, J., Chesi, A., Elci, O., McCormack, S., Roy, S., Kalkwarf, H., Lappe, J., Gilsanz, V., Oberfield, S., Shepherd, J., Kelly, A., Grant, S., Zemel, B. Pediatric bone density is influenced by physical activity and genetic variation at known bone density loci. Accepted for oral presentation at the ASBMR, Seattle, WA, October 9-12, 2015., 2015
  • Binkley, N., Borchardt, G., Fidler, E., Libber, J., Krueger, D., Iglar, P., Lappe, J., Heiner, J., Illgen, R., Squire, M., Coursin, D., Hogan, K. Surgery alters laboratory results: Implications for fracture liaison services. Accepted for poster presentation at the ASBMR, Seattle, WA, October 9-12, 2015., 2015
  • Chesi, A., Roy, S., Mitchell, J., Kalkwarf, H., Lappe, J., Gilsanz, V., Oberfield, S., Shepherd, J., Mahboubi, S., Winer, K., Kelly, A., Grant, S., Zemel, B., McCormack, S. Skeletal Maturation and Genetically Determined Population Ancestry in Non-Obese, Pre-Pubertal Children. Selected for oral presentation at the ASBMR, Seattle, WA, October 9-12, 2015., 2015
  • Zemel, B., Winer, K., Kelly, A., Lappe, J., Shepherd, J., Oberfield, S., Gilsanz, V., Kalkwarf, H. Reference Ranges and Characteristics of Spine Bone Mineral Apparent Density in U.S. Children – Results from the Bone Mineral Density in Childhood Study. Selected for oral presentation at the ASBMR, Seattle, WA, October 9-12, 2015., 2015
  • Zemel, B., Winer, K., Kelly, A., Lappe, J., Shepherd, J., Oberfield, S., Gilsanz, V., Kalkwarf, H. Reference Ranges and Characteristics of Spine Bone Mineral Apparent Density in U.S. Children – Results from the Bone Mineral Density in Childhood Study. Selected for oral presentation at the ASBMR, Seattle, WA, October 9-12, 2015., 2015
  • Armas, L., Watson, P., Gilsanz, V., Hangartner, T., Kalkwarf, H., Oberfield, S., Shepherd, J., Winer, K., Zemel, B., Lappe, J. Greater Bone Accrual Occurs in African American Youth Before and After Puberty Compared to Euro-American Youth. Accepted for Plenary Poster at ASBMR 2015 Annual Meeting, October 9-12, 2015 Seattle, Washington, USA, 2015
  • Binkley, N., Lappe, J., Davies, K., Recker, R. Vitamin D Status and Bone Mineralization: A Histomorphometric Analysis. Accepted for oral presentation at the ASBMR, Seattle, WA, October 9-12, 2015., 2015
  • Hanson, C., Lyden, E., Schwartz, M., Pfeiffer, H., Laughlin, A., Lappe, J. Diet Quality of Adolescent Girls in Relation to Breast Cancer Risk. Fifth International Breast Cancer Prevention Symposium: Epigenome, Environment and Prevention Tools, Le Gosier, Guadeloupe (France) Oct 2-4., 2015
  • The effects of vitamin D supplementation on cancer incidence in older women. Fifth International Breast Cancer Prevention Symposium: Epigenome, Environment and Prevention Tools, Le Gosier, Guadeloupe (France), October 2-4, 2015
  • Osteoporosis Prevention. Creighton University Wellness Program, Omaha NE, 2015
  • Wang, Y., Li, L., Moore, B., Peng, X., Fang, X., Lappe, J., Recker, R., Xiao, P. (2012). MiR-133a in Human circulating monocytes: A potential biomarker associated with postmenopausal osteoporosis. Presented at the ASBMR Topical Meeting: Bone and Skeletal Muscle Interactions. Kansas City MO July 17-18., 2015
  • Peak bone mass. 9th International Symposium on Nutritional Aspects of Osteoporosis (ISNAO), Montreal, Canada, 2015
  • Dairy trial in pubertal girls. 9th International Symposium on Nutritional Aspects of Osteoporosis (ISNAO), Montreal, Canada, 2015
  • Schwartz, M., Laughlin, A., Lappe, J. The association between milk intake and serum vitamin D levels in adolescent girls. Accepted for poster presentation at the International Symposium on Nutritional Aspects of Osteoporosis, Montreal, Canada, June 17-20, 2015., 2015
  • Stress Fractures: Identifiable Risk and Best Practices for Prevention at CHI Sports Medicine Symposium, Omaha, NE, 2015
  • Schwartz, M., Laughlin, A., & Lappe, J. (2014). The Association between Dairy Food Intake and Serum Lipid Levels in Adolescent Females. Podium/Paper presented at 25th Annual Sigma Theta Tau Research Day, Omaha, Nebraska, May 28, 2014., 2015
  • Building Strong Bones for Life: Challenges and Strategies. Interdisciplinary Symposium on Osteoporosis (ISO), Washington, D.C., 2015
  • Transitional Research and Community Engagement, 8th Annual Addressing Health Disparities Seminar, Creighton University, Omaha, 2015
  • Mitchell, J., Chesi, A., Elci, O., McCormack, S., Roy, S., Kalkwarf, H., Lappe, J., Gilsanz, V., Oberfield, S., Shepherd, J., Kelly, A., Grant, S., Zemel, B. The benefits of physical activity on bone density in childhood are dependent on genetic variation at known bone density loci. Presented at the Cold Spring Harbor, Exercise Science and Health, Cold Spring Harbor, NY, March 9-12, 2015., 2015
  • Basile, K., Chesi, A., Mitchell, J., McCormack, S., Roy, S., Kalkwarf, H., Lappe, J., Gilsanz, V., Oberfield, S., Shepherd, J., Kelly, A., Zemel, B., Grant, S. Multiple GWAS-implicated adult height loci operate in the context of pediatric bone mineral density and content determination. Presented at the Endocrine’s Society Annual Meeting, San Diego, CA, March 5-8, 2015., 2015
  • Mitchell, J., Chesi, A., Elci, O., McCormack, S., Roy, S., Kalkwarf, H., Lappe, J., Gilsanz, V., Oberfield, S., Shepherd, J., Kelly, A., Zemel, B., Grant, S. The Skeletal Benefits of Physical Activity in Childhood are Dependent on Genetic Variation at Known Bone Density Loci. Accepted for an oral presentation at the Endocrine’s Society Annual Meeting, San Diego, CA, March 5-8, 2015., 2015
  • Chesi, A., Kalkwarf, H., Mentch, F., Lappe, J., Gilsanz, V., Oberfield, S., Shepherd, J., Bradfield, J., Mahboubi, S., Roy, S., Mitchell, J., Chiavacci, R., Kelly, A., Hakonarson, H., Zemel, B., Grant, S., McCormack, S. Loci Influencing Skeletal Age In Children And Adolescents Identified Through A Trans-Ethnic Appraisal Of Both Common And Rare Genetic Variants. Presented at the Endocrine’s Society Annual Meeting, San Diego, CA, March 5-8, 2015., 2015
  • Cohen, A., Manavalan, S., Kousteni, S., Recker, R., Lappe, J., Dempster, D., McMahon, D., Bucovsky, M., Kamanda-Kosseh, M., Stubby, J., Shane, E. Circulating osteoblast progenitors and IGF-1 receptor density on these cells correlate with bone formation on transiliac biopsies and predict response to teriparatide in premenopausal women with idiopathic osteoporosis. Presented at the Endocrine’s Society Annual Meeting, San Diego, CA, March 5-8, 2015., 2015
  • Cohen, A., Dempster, D., Zhou, H., Recker, R., Lappe, J., Cremers, S., Muller, R., Zwahlen, A., Kamanda-Kosseh, M., Bucovsky, M., Stein, E., Nickolas, T., Shane, E. Healthy premenopausal women with low HDL (less than 50 mg/dL) have significantly lower trabecular bone volume and bone formation rate. Accepted for oral presentation at the Endocrine’s Society Annual Meeting, San Diego, CA, March 5-8, 2015., 2015
  • McCormack, S., Roy, S., Chesi, A., Mitchell, J., Kwalkwarf, H., Lappe, J., Gilsanz, V., Oberfield, S., Shepherd, J., Kelly, A., Grant, S., Zemel, B. Skeletal Maturation, Population Ancestry, and Body Composition in Non-Obese, Pre-pubertal Children. Presented at the Endocrine’s Society Annual Meeting, San Diego, CA, March 5-8, 2015., 2015
  • Chesi, A., Mitchell, J., Kalkwarf, H., Bradfield, J., Lappe, J., McCormack, S., Gilsanz, V., Oberfield, S., Hakonarson, H., Shepherd, J., Kelly, A., Zemel, B., Grant, S. A Trans-Ethnic GWAS Identifies Gender Specific Loci Influencing Pediatric aBMD and BMC at the Distal Radius. Presented at the CHOP Research Poster Day, February 25, 2015., 2015
  • Hangartner, T., Short, D., Gilsanz, V., Kalkwarf, H., Lappe, J., Oberfield, S., Shepherd, J., Zemel, B., Winer, K. (2014). Influence of Anthropometric Parameters on Assessment of Paediatric Bone Mineral Density and Bone Mineral Content. Submitted to the International Bone Densitometry Workshop, Hong Kong, China, October 13-17, 2014., 2014
  • Tribble, M., Cohen, A., Bakker, C., Lappe, J., Recker, R., Nishiyama, K., Rubin, M., Bilezikian, J., Shane, E., Liu, X. Increased Endocortical Formation and Periosteal Resorption at the Distal Tibia in Premenopausal Women with Idiopathic Osteoporosis Treated with 18 Months of Teriparatide . Presented at the Annual Meeting of the American Society for Bone and Mineral Research. Houston, TX, September 15, 2014., 2014
  • Cohen, A., Manavalan, S., Kousteni, S., Recker, R., Lappe, J., Dempster, D., McMahon, D., Bucovsky, M., Kamanda-Kosseh, M., Stubby, J., Shane, E. Early increases in IGF-1 receptor density on circulating osteogenic progenitor cells predict responsiveness to teriparatide. Presented at the Annual Meeting of the American Society for Bone and Mineral Research. Houston, TX, September 15, 2014., 2014
  • Mitchell, J., Chesi, A., Elci, O., McCormack, S., Kalkwarf, H., Lappe, J., Gilsanz, V., Oberfield, S., Shepherd, J., Kelly, A., Zemel, B., Grant, S. Adult Bone Density Loci and Sex Specific Bone Mass in Childhood. Presented at the Annual Meeting of the American Society for Bone and Mineral Research. Houston, TX, September 15, 2014., 2014
  • Chesi, A., Mitchell, J., Kalkwarf, H., Bradfield, J., Lappe, J., McCormack, S., Gilsanz, V., Oberfield, S., Hakonarson, H., Shepherd, J., Kelly, A., Zemel, B., Grant, S. A Trans-ethnic Genome-wide Association Study Identifies Gender Specific Loci Influencing Pediatric BMD and BMC at the Distal Radius. Presented at the Annual Meeting of the American Society for Bone and Mineral Research. Houston, TX, September 15, 2014., 2014
  • Cohen, A., Kamanda-Kosseh, M., Recker, R., Lappe, J., Dempster, D., Zhou, H., Cremers, S., Bucovsky, M., Stubby, J., Shane, E. Characteristics of premenopausal women with idiopathic osteoporosis who experience significant bone loss after teriparatide cessation. Presented at the Annual Meeting of the American Society for Bone and Mineral Research. Houston, TX, September 14, 2014., 2014
  • Binkley, N., Singh, R., Lappe, J., Krueger, D., Drezner, M., Blank, R. A New Paradigm for Vitamin D Supplementation: Treat to Target Using a Vitamin D Panel. Presented at the Annual Meeting of the American Society for Bone and Mineral Research. Houston, TX, September 14, 2014., 2014
  • Rosauer, B., Akhter, M., Kimmel, D., Lappe, J., Recker, R. Osteocyte Lacunar Density is Breed Related in Mice. Presented at the Annual Meeting of the American Society for Bone and Mineral Research. Houston, TX, September 12, 2014., 2014
  • Mitchell, J., Chesi, A., Elci, O., McCormack, S., Kalkwarf, H., Lappe, J., Gilsanz, V., Oberfield, S., Shepherd, J., Kelly, A., Zemel, B., Grant, S. (2014). Adult bone density loci and sex specific bone mass in childhood. Presented at the AAOS/CORR/ORS Research Symposium: Musculoskeletal Sex Differences Through the Lifespan, Rosemont, IL, July 30-Aug 1., 2014
  • Zemel, B., Kalkwarf, H., Gilsanz, V., Lappe, J., Oberfield, S., Shepherd, J., Winer, K. (2014). Lessons learned from assessing skeletal growth using DXA technology. Presented at the AAOS/CORR/ORS Research Symposium: Musculoskeletal Sex Differences Through the Lifespan, Rosemont, IL, July 30-Aug 1., 2014
  • Strong bones, strong minds talk at LaVista Public Library, 2014
  • Schwartz, M., Laughlin, A., & Lappe, J. (March 2014). The Association between Dairy Food Intake and Serum Lipid Levels in Adolescent Females. Podium/Paper presented at 38th Annual Midwest Nursing Research Conference, St. Louis, Missouri, April 18, 2014., 2014
  • Hangartner, T., Short, D., Gilsanz, V., Kalkwarf, H., Lappe, J., Oberfield, S., Shepherd, J., Zemel, B., Winer, K. (2014). Inclusion of anthropometric parameters in the creation of reference curves for pediatric bone mineral density and bone mineral content: Impact on classification of below-normal individuals. Presented at the WCO IOF-ESCEO14 Congress, Seville (Spain), April 2-5, 2014., 2014
  • Hangartner, T., Short, D., Gilsanz, V., Kalkwarf, H., Lappe, J., Oberfield, S., Shepherd, J., Zemel, B., Winer, K. (2013). Inclusion of anthropometric parameters in the creation of reference curves for pediatric bone mineral density and bone mineral content: Impact on classification of below-normal individuals. Presented at the Annual Meeting of the American Society for Bone and Mineral Research. Baltimore, MD, October 7., 2013
  • Cohen A., Costa A., Recker R.R., Lappe J.M., Cremers S., Dempster D.W., Zhou H., Zwahlen A., Müller R., Stein E., Nickolas T., Rosen C., Shane E. (2013). Lower bone volume fraction and bone formation rate in premenopausal women with abdominal obesity are associated with less physical activity and higher serum sclerostin. Presented at the Annual Meeting of the American Society for Bone and Mineral Research. Baltimore, MD, October 6., 2013
  • Zemel, B., Kalkwarf, H., Li, M., Deliard, S., Kim, C., Qu, L., Chiavacci, R., Paulhamus, D., Lappe, J., Gilsanz, V., Hakonarson, H., Oberfield, S., Shepherd, J., Voight, B., Kelly, A., Grant, S. (2013). Age effect on pediatric longitudinal BMD by multiple loci uncovered in adult BMD-related GWAS meta-analyses. Presented at the Annual Meeting of the American Society for Bone and Mineral Research. Baltimore, MD, October 6., 2013
  • Nishiyama, K., Wang, J., Young, P., Recker, R., Lappe, J., Cremers, S., Guo, X., Shane, E., Cohen, A. (2013). Teriparatide is associated with improved microarchitecture and estimated bone strength in premenopausal women with idiopathic osteoporosis: An HR-pQCT study. Presented at the Annual Meeting of the American Society for Bone and Mineral Research. Baltimore, MD, October 5., 2013
  • Kepley, A., Shen, W., Mayer, L., Shane, E., Young, P., Zhang, C., Recker, R., Lappe, J., Cohen, A. (2013). Premenopausal women with idiopathic osteoporosis and those with anorexia nervosa have similar bone structural defects but differ in terms of marrow fat. Presented at the Annual Meeting of the American Society for Bone and Mineral Research. Baltimore, MD, October 5., 2013
  • Lewis, J., Ivey, K., Radavelli-Bagatini, S., Rejnmark, L., Chen, J., Simpson, J., Lappe, J., Mosekilde, L., Prentice, R., Prince, R. (2013). The cardiovascular safety of calcium supplementation with or without vitamin D in elderly women: A collaborative meta-analysis of published and unpublished trial level evidence from randomized controlled trials. Presented at the Annual Meeting of the American Society for Bone and Mineral Research. Baltimore, MD, October 4., 2013
  • Zemel, B., Kalkwarf, H., Li, M., Deliard, S., Kim, C., Chiavacci, R., Hakonarson, H., Paulhamus-Giorda, D., Kelly, A., Lappe, J., Gilsanz, V., Oberfield, S., Shepherd, J., Qu, L., Voight, B., Grant, S. (2013). Role of bone-associated loci identified in GWAS meta-analyses in the context of longitudinal pediatric BMD in European Americans. Accepted for presentation at the 6th International Conference on Children’s Bone Health, Rotterdam, Netherlands, June 22-25., 2013
  • Bradfield, J., Deliard, S., Kim, C., Chiavacci, R., Lappe, J., Kalkwarf, H., Gilsanz, V., Hakonarson, H., Oberfield, S., Shepherd, J., Kelly, A., Zemel, B., Grant, S. (2013). The STARD3NL locus is strongly associated with pediatric spine bone mineral in a mixed model meta-analysis of known adult loci. Presentation for European Society of Human Genetics, Paris, France, June 8-11., 2013
  • Travers-Gustafson, D., Lappe, J. (2013) Nurses taking initiative to promote bone health: A multilevel model for preventing osteoporosis. Presented at the Interdisciplinary Osteoporosis Symposium, Chicago, IL, April 19-21., 2013
  • Community education at Swanson Public Library, “Boning Up On Osteoporosis: Promotion of Bone Health Across the Life Span”, 2013
  • Schwartz, M., Laughlin, A., Begley, M., Danis, L., & Lappe, J. (2013). Infant feeding practices and effects on adolescent growth. Poster presented at St. Albert’s Day/University Research Day. Creighton University, Omaha, Nebraska, March 28, 2013., 2013
  • Schwartz, M., Lauglin, A., Begley, M., Danis, L., Lappe, J. Infant feeding practices and effects on adolescent growth. (2013). Poster presented at the Midwest Nursing Research Conference, Chicago IL, March 8., 2013
  • Abbott, A., Fuji, K. T., Galt, K. A., Lappe, J. M., & Howell, E. (2013). Podium presentation accepted “Exploring Health Literacy in Persons with Type 2 Diabetes Experiencing the Digital Divide”, Health Literacy Nebraska Statewide Summit, Lincoln, NE, January 30., 2013
  • Akhter, M., Vennin, S., Turner, J., Danforth, J., Lappe, J., Watson, P., Recker, R. (2013). Intrinsic properties of bone tissue in biopsies from postmenopausal women. Presentation at the ORS Annual Meeting. San Antonio, TX, January 26-29., 2013
  • Vitamin D finds its place in the sun: Importance for prevention of disease. Governor’s Women’s Health Conference, Lincoln NE., 2012
  • Wren, T., Kalkwarf, H., Zemel, B., Lappe, J., Shepherd, J., Oberfield, S., Winer, K., Gilsanz, V. (2012). Longitudinal tracking of DXA bone measures in children and adolescents over a 6-year period. Presented at the 34th Annual Meeting of the American Society for Bone and Mineral Research. Minneapolis, MN, October 12-15., 2012
  • Wang, Y., Moore, B., Peng, XH., Fang, X., Lappe, J., Recker, R., Xiao, P. (2012). MiR-422a in human circulating monocytes is a potential microRNA biomarker underlying postmenopausal osteoporosis. Presented at the 34th Annual Meeting of the American Society for Bone and Mineral Research. Minneapolis, MN, October 12-15., 2012
  • Cohen, A., Young, P., Stein, E., Dempster, D., Zhou, H., Recker, R., Lappe, J., Zhang, C., McMahon, D., Cremers, S., Zwahlen, A., Muller, R., Shane, E. (2012). Absence of the anabolic window characterizes premenopausal women with idiopathic osteoporosis who do not respond to teriparatide. Presented at the 34th Annual Meeting of the American Society for Bone and Mineral Research. Minneapolis, MN, October 12-15., 2012
  • Lappe, J., Zemel, B., Watson, P., Fang, X., Gilsanz, V., Kalkwarf, H., Oberfield, S., Shepherd, J., Winer, K. (2012). Does stage of sexual maturation determine the relationship of calcium intake and physical activity to bone mass accrual. Presented at the 34th Annual Meeting of the American Society for Bone and Mineral Research. Minneapolis, MN, October 12-15., 2012
  • Campbell, S., Yuya, P., Polly, B., Hurley, D., Turner, J., Lappe, J., Recker, R., Akhter, M. (2012). Viscoelastic mapping of transmenopausal bone biopsies. Presented at the 34th Annual Meeting of the American Society for Bone and Mineral Research. Minneapolis, MN, October 12-15., 2012
  • Farlay, D., Bala, Y., Bare, S., Lappe, J., Recker, R., Boivin, G. (2012). Modifications of bone material properties early detected after one year of menopause in women. Presented at the 34th Annual Meeting of the American Society for Bone and Mineral Research. Minneapolis, MN, October 12-15., 2012
  • Campbell, S., Yuya, P., Polly, B., Hurley, D., Turner, J., Lappe, J., Recker, R., Akhter, M. (2012). Viscoelastic mapping of transmenopausal bone biopsies. Presented at the ASBMR Topical Meeting: Bone and Skeletal Muscle Interactions. Kansas City MO July 17-18., 2012
  • Zwahlen, A., Christen, D., Cohen, A., Shane, E., Nickolas, T., Stein, E., Recker, R., Lappe, J., Zhou, H., Dempster, D., Muller, R. (2011). Bone strength surrogates in iliac crest biopsies. Submitted to European Society of Biomechanics Annual Meeting. Lisbon, Portugal. July, 1-4, 2012., 2012
  • Lappe, J., Watson, P., Gilsanz, V., Kalkwarf, H., Oberfield, S., Shepherd J., Zemel, B., Winer, K. The Relationship of Weight-bearing Physical Activity and Dietary Calcium Intake with Bone Mass Accrual in the Bone Mineral Density in Childhood Study Cohort. Oral presentation at 8th International Symposium on Nutritional Aspects of Osteoporosis. Lausanne Switzerland May 17-19, 2012., 2012
  • Elliott, E., Hanson, C., Anderson-Berry, A., Lyden, L., Armas, L., Rafferty, K., Lappe, J. (2011). Omega-3 and Omega-6 intakes in adolescents of childbearing age. Accepted for Pediatric Academic Society Annual Meeting. Boston, MA, April 28-May 1, 2012., 2012
  • Hanson, C., Anderson-Berry, A., Lyden, L., Armas, L., Rafferty, K., Lappe, J. (2011). Vitamin D intake over time in adolescent girls. Accepted for Pediatric Academic Society Annual Meeting. Boston, MA, April 28-May 1, 2012., 2012
  • Dudley, L., Hanson, C., Anderson-Berry, A., Lyden, L., Armas, S., Rafferty, K., Lappe, J. Folate intake over time in adolescents of childbearing age. Presented at the Pediatric Academic Society Annual Meeting. Boston, MA, April 28-May 1, 2012., 2012
  • Vitamin D and Cancer: State of the Science. Webinar broadcast in Canada, sponsored by Diasorin, Inc., 2012
  • Health Promotion Research: Ideas to Implementation. Sigma Theta Tau chapter at Midlands University, Fremont NE., 2012
  • Vitamin D Update: Taking Aim at Cancer. VA Nebraska-Western Iowa Health Care System. Omaha NE., 2012
  • The role of vitamin D in cancer. Wings of Hope, Council Bluffs IA., 2011
  • Cohen, A., Stein, E., Dempster, D., Zhou, H., Cremers, S., Rosen, C., Nickolas, T., Kohler, T., Wirth, A., Van Lenthe, H., Muller, R., Chen, P., Recker, R., Lappe, J., Shane, E. (2011). Idiopathic osteoporosis in premenopausal women: Bone turnover provides clues to pathogenesis. Presented at the 33rd Annual Meeting of the American Society for Bone and Mineral Research. San Diego, CA, September 16-21., 2011
  • Cohen, A., Boutroy, S., Stein, E., Liu, X., Lappe, J., Recker, R., Dempster, D., Zhou, H., McMahon, D., Zhang, C., Chen, P., Zhou, B., Wang, J., Guo, X., Shane, E. (2011). High resolution peripheral quantitative computed tomography (HRpQCT) detects improved trabecular volumetric BMD and microarchitecture in premenopausal women with idiopathic osteoporosis treated with teriparatide. Presented at the 33rd Annual Meeting of the American Society for Bone and Mineral Research. San Diego, CA, September 16-21., 2011
  • Cohen, A., Stein, E., Dempster, D., Zhou, H., Recker, R., Lappe, J., Zhang, C., Mcmahon, D., Chen, P., Pandit, K., Rosen, C., Shane, E. (2011). In premenopausal women with idiopathic osteoporosis, baseline bone turnover predicts response to teriparatide. Presented at the 33rd Annual Meeting of the American Society for Bone and Mineral Research. San Diego, CA, September 16-21., 2011
  • Cohen, A., Stein, E., Dempster, D., Recker, R., Lappe, J., Zhou, H., Nickolas, T., Zwahlen, A., Kohler, T., Muller, R., Chen, P., Pandit, K., Shane, E. (2011). Teriparatide for premenopausal women with idiopathic osteoporosis: A paired transiliac bone biopsy study. Presented at the 33rd Annual Meeting of the American Society for Bone and Mineral Research. San Diego, CA, September 16-21., 2011
  • Wren, T., Shepherd, J., Kalkwarf, H., Zemel, B., Lappe, J., Oberfield, S., Winer, K., Gilsanz, V. (2011). Racial and ethnic disparity in fracture risk among pediatric populations in the United States. Presented at the 33rd Annual Meeting of the American Society for Bone and Mineral Research. San Diego, CA, September 16-21., 2011
  • Liu, X., Cohen, A., Stein, E., Dempster, D., Zhou, H., Lappe, J., Recker, R., Chen, P., McMahon, D., Shane, E. (2011). Increased trabecular tissue mineral density partially explains the improvement in trabecular volumetric BMD in premenopausal women with idiopathic osteoporosis treated with teriparatide. Presented at the 33rd Annual Meeting of the American Society for Bone and Mineral Research. San Diego, CA, September 16-21., 2011
  • Xu X, Zhou Y, Bu F, Ye A, Zhou B, Recker R, Lappe J, Zhao L. (2011) DNA Methylation Levels of CYP2R1 and CYP24A1 Predict Vitamin D Dose-Response Variation. Presented at the 33rd Annual Meeting of the American Society for Bone and Mineral Research. San Diego CA, September 16-21. Selected for oral presentation and the 2011 ASBMR Young Investigator Travel Grant., 2011
  • Vitamin D Update: Taking Aim at Cancer. Physician Noon Conference, Good Samaritan Hospital, Kearney NE, 2011
  • Randomized Trial of Vitamin D3 & Calcium Supplementation to Reduce Risk of Cancer. Vitamin D and Cancer Conference, London England., 2011
  • Osteoporosis: Not Just a Woman’s Disease, and Racial and Ethnic Differences in Osteoporosis. National Association of Orthopedic Nurses, 31st Annual Conference, Baltimore MD., 2011
  • Vitamin D and Cancer: State of the Science. Webinar broadcast in Canada, sponsored by Diasorin, Inc, 2011
  • Hangartner, T., Short, D., Zemel, B., Gilsanz, V., Kalkwarf, K., Lappe, J., Mahboubi, S., Oberfield, S., Shepherd, J., Winer, K. (2010). Modeling of Pediatric Spine BMD with Consideration of Anthropometric Parameters. (Poster) IOF-sponsored 1st Asia-Pacific Osteoporosis Meeting in Singapore, December 13., 2010
  • Kunz, I., Lappe, J., Recker, R., Riegger, C., Weber, P., Heaney, R. (2010). A Randomized, Placebo-controlled, Double-blind Pilot Study to Investigate the Effect of a Combination of Genistein, Polyunsaturated Fatty Acids and Vitamins K1 and D3 on Bone Health and Safety in Postmenopausal Women (PMW). (Oral) Presented at the 9th International Symposium on the Role of Soy in Health Promotion and Chronic Disease Prevention and Treatment. Washington, D.C., October 19., 2010
  • Cohen, A., Dempster, D., Stein, E., Nickolas, T., Zhou, H., McMahon, D., Muller, R., Kohler, T., Lappe, J., Rogers, H., Recker, R., Shane, E. (2010). Is increased marrow adipocity the cause or the result of bone microarchitectural abnormalities in premenopausal women with idiopathic osteoporosis? (Poster #MO0035) Presented at the 32nd Annual Meeting of the American Society for Bone and Mineral research. Toronto Canada, October 15-19., 2010
  • Misof, B., Cohen, A., Roschger, P., Dempster, D., Rogers, H., Stein, E., Zhou, H., Nickolas, T., McMahon, D., Lappe, J., Recker, R., Klaushofer, K., Shane, E. (2010). Evidence for reduced mineralization of bone matrix in female idiopathic osteoporosis. (Poster #MO0045) Presented at the 32nd Annual Meeting of the American Society for Bone and Mineral research. Toronto Canada, October 15-19., 2010
  • Buchinger, B., Gamsjaeger, S., Cohen, A., Stein, E., Dempster, D., Rogers, H., Recker, R., Lappe, J., Nickolas, T., Zhou, H., McMahon, D., Paschalis, E., Shane, E., Klaushofer, K. (2010). Altered bone matrix composition in premenopausal women with idiopathic osteoporosis as determined by Raman and FTIR Microspectroscopy. (Poster #SU0365) Presented at the 32nd Annual Meeting of the American Society for Bone and Mineral research. Toronto Canada, October 15-19., 2010
  • Shane, E., Cohen, A., Cremers, S., Rogers, H., Dworakowski, E., Lappe, J., Recker, R., Stein, E., Nickolas, T., Kohler, T., Muller, R., Rosen, C., Dempster, D. (2010). Serum sclerostin is inversely associated with bone remodelling in normal premenopausal women but not in premenopausal women with idiopathic osteoporosis. (Poster #SU0371) Presented at the 32nd Annual Meeting of the American Society for Bone and Mineral Research. Toronto Canada, October 15-19., 2010
  • Lappe, J., Heaney, R., Davies, K., Cullen, D. (2010). Magnitude and timing of peak bone mineral accrual in young girls. (Poster #FR0010) Presented at the 32nd Annual Meeting of the American Society for Bone and Mineral Research. Toronto Canada, October 15-19., 2010
  • Cohen, A., Lang, T., Rogers, H., Stein, E., Guo, X., Liu, X., Dempster, D., McMahon, D., Lappe, J., Zhang, C., Recker, R., Shane, E. (2010). Central QCT reveals cortical and trabecular structural deficits in premenopausal women with idiopathic osteoporosis whether diagnosis is based on fragility fracture or low areal bone mineral Density. (Poster #1128) Presented at the 32nd Annual Meeting of the American Society for Bone and Mineral research. Toronto Canada, October 15-19., 2010
  • Zhou, Y., Bu, F., Lappe, J., Armas, L., Recker, R., Zhao, L. (2010). CYP2R1 is a potential candidate for predicting serum 25(OH)D variation as suggested by genetic and epigenetic studies. (Poster #1167) Presented at the 32nd Annual Meeting of the American Society for Bone and Mineral research. Toronto Canada, October 15-19., 2010
  • Zemel, B., Kalkwark, H., Kelly, A., Lappe, J., Leonard, M., Grant, S., Mahboubi, S., Frederick, M., Oberfield, S., Shepherd, J., Winer, K. (2010). The impact of growth and development on bone mineral accretion of the total body (less head) and lumbar spine during childhood and adolescence; A report from the bone mineral density in childhood study group. (Poster #1175) Presented at the 32nd Annual Meeting of the American Society for Bone and Mineral research. Toronto Canada, October 15-19., 2010
  • Gilsanz, V., Chalfant, J., Kalkwarf, H., Zemel, B., Lappe, J., Oberfield, S., Shepherd, J., Hangartner, T., Frederick, M., Huang, X., Mahboubi, S., Desmangles, J-C., Wren, T., Winer, K. (2010). Age at onset of puberty predicts bone mass in young adulthood. (Poster #1179) Presented at the 32nd Annual Meeting of the American Society for Bone and Mineral research. Toronto Canada, October 15-19., 2010
  • Kunz, I., Lappe, J., Recker, R., Riegger, C., Weber, P., Heaney, R. (2010) Effect of Combination of Genistein, Polyunsaturated Fatty Acids (N-3PUFAS) and Vitamin K and D3 on Bone Mineral Density (BMD) in Postmenopausal Women. Poster presentation at the IOF World Congress on Osteoporosis & 10th European Congress on Clinical and Economic Aspects of Osteoporosis and Osteoarthritis, Florence, Italy,, 2010
  • Osborne, D., Lappe, J, Cullen, D, Watson, P. (2010) Assessing longitudinal growth in bone density in females at the heel using ultrasound. Annual Meeting of the Human Biology Association; Poster; April 14, 2010, Albuquerque, NM; American Journal of Human Biology 22(2):266., 2010

Research and Scholarship

Research and Scholarship Interests

  • Health promotion in general Bone health and osteoporosis Calcium and vitamin D nutrition Cancer prevention

Current Research Projects

  • vitamin D and cancer prevention exercise vs risedronate in bone health in mid-life women

Grant Funding Received

  • Lappe, J. and Laughlin A. The Effects of a Daily Serving of Dried Plums on Bone Mass Accrual in Adolescent Females: A Pilot Study. Submitted to the California Plum Board, Sept 2015.
  • Binkley, N., Lappe, J. (co-PI’s), Buehring, B., Gangnon, R., Heiderscheit, B., Engelman, C., Schoeller, D. Effects of muscle/function by personalized vitamin D dosing in older adults (MYVITD Study). Submitted to NINR, March 5, 2015. Not funded.
  • Binkley, N., Lappe, J. (co-PI’s), Buehring, B., Gangnon, R., Heiderscheit, B., Engelman, C., Schoeller, D. Effects of muscle/function by personalized vitamin D dosing in older adults (MYVITD Study). Submitted to NINR, June 5, 2014. Not funded.
  • Lappe, J., Recker, R., Wang, T. Hoffman, U. Coronary Artery Calcification and Long-Term Calcium and Vitamin D Supplementation. Submitted to the National Heart, Lung, and Blood Institute, Oct 2012. Not funded.
  • Lappe, J., Gilsanz, V., Kwalkarf, H., Zemel, B., Shepherd, J., Hangartner T. (2011) Prospective study of bone accrual though young adulthood: Extension of the BMDCS. Submitted to NICHD, October 2011. Not funded.
  • Lappe, J., Gilsanz, V., Kwalkarf, H., Zemel, B., Shepherd, J., Hangartner T. (2011) Prospective study of bone accrual though young adulthood: Extension of the BMDCS. Submitted to NICHD, February. Not funded.
  • Waltman, N., Bilek, L., Mack, L., Kupzyk, K., Cullen, D., Lappe, J. Bone-Loading Exercises versus Risedronate on Bone Health in Post-Menopausal Women. Funded by National Institute of Nursing, October 2014.
  • Lappe, J., Recker, R., McClellan, J. (2013) Pilot Study to Determine Whether Spondylolysis in Children and Adolescents is Associated with Bone Mineral Content, Serum 25-hydroxyvitamin D and Calcium Intake. Funded by the Nebraska Spine Center ($6,535).
  • Lappe, J. (2010) Administrative Supplement to RO1CA129488-01A2 Clinical Trial of Vitamin D3 to Reduce Cancer Risk in Postmenopausal Women, $46,198.
  • Potthoff, M., Carrico, C. Doll, J., DeFreece, T, Jensen, G., Lappe, J, & McCafferty, K. (September 2016-October 2018). Cultivating Collaboration: Building a Successful Collaborative Care Model in an Academic Health Partnership. Accelerating Interprofessional Community-Based Education and Practice. Funded by the National Center for Interprofessional Practice and Education in partnership with the Robert Wood Johnson Foundation, the John A. Hartford Foundation, the Josiah Macy Jr. Foundation and the Gordon and Betty Moore Foundation. $100,000.
  • Deng, H., Liu, Y., Taylor, C., Shen, H., Serou, M., Wang, Y., Lappe, J. Metagenomic study of gut for osteoporosis risk – submitted February 2017.
  • Gletsu Miller, N., Weaver, C., Hannon, T., McCabe, G., Martin, B., Gallant, K., Leidy, H., Knutson, K., Lappe, J., Janz, K. “Camp DASH for Glucose,” submitted to the NIH February 2017.

Awards and Honors

  • Joan Norris Mentorship Award, the Iota Tau Chapter of Sigma Theta Tau, the National Honor Society of Nursing, 2014
  • Induction into Alpha Sigma Nu, the honor society of Jesuit institutions of higher education, 2011