Himanshu Agarwal, MD

Department

Medicine

Position

Assistant Professor

Articles

• JACC
  Christopher R. Ellis, MD, Dhanunjaya Lakkireddy, MD, Akash Makkar, MD, Mohamad Alkhouli, MD, Megan Coylewright, MD, Himanshu Agarwal, MD, Larry Chinitz, MD, Mohit K. Turagam, MD, Robert Percell, MD, James V. Freeman, MD Concomitant Catheter Ablation and Left Atrial Appendage Occlusion with the Amulet Occluder from EMERGE LAA; Post-Approval Study Christopher R. Ellis, MD, Dhanunjaya Lakkireddy, MD, Akash Makkar, MD, Mohamad Alkhouli, MD, Megan Coylewright, MD, Himanshu Agarwal, MD, Larry Chinitz, MD, Mohit K. Turagam, MD, Robert Percell, MD, James V. Freeman, MD . JACC Clinical Electrophysiology 2025 ( Article in press ) 2025
• Cardiovascular Revascularization Medicine
  Shah AP,, Freeman JV, Alkhouli M, Agarwal H, Coylewright M, Makkar A, Anderson J, Gage R, Freixa X, Nielsen-Kudsk JE, Lakkireddy D. Outcomes for Single Antiplatelet, Dual Antiplatelet, or Oral Anticoagulation after Amulet: Insights from EMERGE LAA Post-Approval Study. Shah AP, Freeman JV, Alkhouli M, Agarwal H, Coylewright M, Makkar A, Anderson J, Gage R, Freixa X, Nielsen-Kudsk JE, Lakkireddy D. Cardiovascular Revascularization Medicine 2025 ( Article in press ) 2025
• Circulation
  Steg PG, Szarek M, Jukema JW, Bhatt DL, Bittner VA, Diaz R, Fazio S, Garon G, Goodman SG, Harrington RA, White HD, Zeiher AM, Schwartz GG; Agarwal H; et.al. Relation of Low-Density Lipoprotein Cholesterol, High-Sensitivity C-Reactive Protein, and Lipoprotein(a) Each to Future Cardiovascular Events and Death After Acute Coronary Syndrome on High-Intensity Statin Therapy: An Analysis of the Placebo Arm of ODYSSEY OUTCOMES. Steg PG, Szarek M, Jukema JW, Bhatt DL, Bittner VA, Diaz R, Fazio S, Garon G, Goodman SG, Harrington RA, White HD, Zeiher AM, Schwartz GG; Agarwal H; et.al. ODYSSEY OUTCOMES Investigators. Circulation. 2025 Apr 8;151(14):1047-1050. doi: 10.1161/CIRCULATIONAHA.124.071269. Epub 2025 Apr 7. PMID: 40193536
  151 2025
• Eur Heart J Acute Cardiovasc Care
  Goodman SG, Steg PG, Szarek M, Bhatt DL, Bittner VA, Diaz R, Harrington RA, Jukema JW, White HD, Zeiher AM, Manvelian G, Pordy R, Poulouin Y, Stipek W, Garon G, Schwartz GG; Agarwal H; et.al. Safety of the PCSK9 Inhibitor Alirocumab: Insights From 47,296 Patient-Years of Observation. Goodman SG, Steg PG, Szarek M, Bhatt DL, Bittner VA, Diaz R, Harrington RA, Jukema JW, White HD, Zeiher AM, Manvelian G, Pordy R, Poulouin Y, Stipek W, Garon G, Schwartz GG; Agarwal H; et.al. ODYSSEY OUTCOMES Investigators. Eur Heart J Cardiovasc Pharmacother. 2024 Jul 16;10(4):342-352. doi: 10.1093/ehjcvp/pvae025. PMID: 38658193.
  10 2024
• CHI Health Better You Blog
  Agarwal, H, Agarwal, H. Heart Valve Disease: Is it Worse Than Cancer? CHI Health Better You Blog, Heart Health. June 4, 2024. https://blogs.chihealth.com/en.blogs.author.himanshu-agarwal 2024
• JACC Cardiovasc Interv
  Aarnink EW, Maarse M, Agarwal H, et al Left Atrial Appendage Occlusion in Patients With Anticoagulation Failure vs Anticoagulation Contraindication. Aarnink EW, Maarse M, Agarwal H, et al . JACC Cardiovasc Interv. 2024 May 8:S1936-8798(24)00648-4. doi: 10.1016/j.jcin.2024.04.012. Online ahead of print.PMID: 38795093 2024
• Circulation
  Kapadia SR, Krishnaswamy A, Whisenant B, Potluri S, Iyer V, Aragon J, Gideon P, Strote J, Leonardi R, Agarwal H, Larrain G, Sanchez C, Panaich SS, Harvey J, Vahl T, Menon V, Wolski K, Wang Q, Leon MB Concomitant Left Atrial Appendage Occlusion and Transcatheter Aortic Valve Replacement Among Patients With Atrial Fibrillation Kapadia SR, Krishnaswamy A, Whisenant B, Potluri S, Iyer V, Aragon J, Gideon P, Strote J, Leonardi R, Agarwal H, Larrain G, Sanchez C, Panaich SS, Harvey J, Vahl T, Menon V, Wolski K, Wang Q, Leon MB. Circulation. 2024 Mar 5;149(10):734-743. doi: 10.1161/CIRCULATIONAHA.123.067312. Epub 2023 Oct 24
  149 2024
• JACC Cardiovasc Interv
  Mohamad Alkhouli, Akash Makkar, James V Freeman, Christopher R Ellis, Atman P Shah, Hemal Gada, Megan Coylewright, Monica Lo, Himanshu Agarwal, Dhanunjaya Lakkireddy Amulet Occluder Implantation in Patients With Failed Prior Left Atrial Appendage Occlusion: EMERGE LAA Insights Mohamad Alkhouli, Akash Makkar, James V Freeman, Christopher R Ellis, Atman P Shah, Hemal Gada, Megan Coylewright, Monica Lo, Himanshu Agarwal, Dhanunjaya Lakkireddy JACC Cardiovasc Inter 2024 Feb 12;17(3):457-459. doi: 10.1016/j.jcin.2023.12.012
  17 2024
• JACC Cardiovasc Interv
  Alkhouli M, Freeman JV, Ellis CR, Shah AP, Gada H, Coylewright M, Lo M, Makkar A, Agarwal H, Lakkireddy D First Experience With Amulet in the United States: Early Insights From EMERGE LAA Postapproval Study. Alkhouli M, Freeman JV, Ellis CR, Shah AP, Gada H, Coylewright M, Lo M, Makkar A, Agarwal H, Lakkireddy D. JACC Cardiovasc Interv. 2024 Jan 19:S1936-8798(23)01553-4. doi: 10.1016/j.jcin.2023.11.027. 2024
• JACC Cardiovasc Interv
  Mesnier J, Simard T, Jung RG, Agarwal H et.al. Persistent and Recurrent Device-Related Thrombus After Left Atrial Appendage Closure: Incidence, Predictors, and Outcomes. Mesnier J, Simard T, Jung RG, Agarwal H et.al. JACC Cardiovasc Interv. 2023 Nov 27;16(22):2722-2732. doi: 10.1016/j.jcin.2023.09.017.PMID: 38030358 2023
• J American College of Cardiology Cardiovascular Interv
  Aggarwal, G, Delcore, M; Agarwal, H. Transcatheter Aortic Valve Replacement With Self-Expanding Acurate Neo2 Valve Versus Acurate Neo Valve: A Meta-Analysis. . G Aggarwal, M Delcore, H Agarwal et al J Am Coll Cardiol Intv 2023 Feb, 16 (4_Supplement) S88-89, p. S88-89 2023
• J American College of Cardiology Cardiovascular Interv
  Aggarwal, G, M Delcore, H Agarwal Left Atrial Appendage Occlusion With Watchman® Device in Patients With Non-Valvular Atrial Fibrillation and End-Stage Chronic Kidney Disease on Hemodialysis J Am Coll Cardiol Intv 2023 Feb, 16 (4_Supplement) S88-89 J Am Coll Cardiol Intv 2023 Feb, 16 (4_Supplement) S102plement) S102 2023
• J American College of Cardiology Cardiovascular Interv
  Aggarwal, G, DelCore, M; Agarwal, H Orbital Atherectomy During Percutaneous Coronary Intervention for Severely Calcified Coronary Lesions in Patients With and Without Diabetes Mellitus: A Meta-Ananlysis. G Aggarwal, M Delcore, H Agarwal et al J Am Coll Cardiol Intv 2023 Feb, 16 (4_Supplement) S96–S97 2023
• Catheter Cardiovasc Interv
  Ismayl, M, M Balakrishna, A; M Fahmy, M; Thandra, A; Gill, G; Hiu, F; Agarwal, H Impact of sex on in hospital mortality and 90-day readmissions in patients undergoing transcatheter mitral valve replacement (TMVR): Analysis from nationwide readmission database. Mahmoud Ismayl MD, Akshay Machanahalli Balakrishna MD, Mostafa Mahmoud Fahmy MD, Abhishek Thandra MD, Gauravpal S. Gill MD, Fang Niu PhD, Himanshu Agarwal MD et al. Catheter Cardiovasc Interv. 2023 Jan 8. doi: 10.1002/ccd.30549. Online ahead of print.PMID: 36617383 2023
• Coronary Artery Diesease
  Thandra, A, Agarwal, H Sex difference in clinical and procedural outcomes in patients undergoing coronary atherectomy; a systematic review and metanalysis. Thandra A, Agarwal H et. Al Coron Artery Dis. 2022 Dec 1;33(8):634-642. doi10.1097/MCA.0000000000001187. Epub 2022 Oct 17.PMID: 36238981
  33, p. 634-642 2022
• New England Journal of Medicine
  Kapadia, SR, Makkar, R; Leon, M; Agarwal, H Cerebral Embolic Protection during Transcatheter Aortic-Valve replacement. Kapadia SR, Makkar R, Leon M, Agarwal H et al. PROTECTED TAVR investigators N Engl J Med. 2022 Oct 6 ; 387 (14) :1253-1263
  387, p. 1253-1263 2022
• Circulation
  Hagstrom, E, Steg, PG, Szarek, M; Bhatt, DL, Bittner, VA; Danchin, N; Agarwal, H Apolipoprotien B, Residual Cardiovascular Risk after Acute Coronary Syndrome, and effects of Alirocumab Hagström E, Steg PG, Szarek M, Bhatt DL, Bittner VA, Danchin N, Agarwal H et. al ; ODYSSEY OUTCOMES Investigators. Circulation. 2022 Aug 30;146(9):657-672. doi: 10.1161
  146, p. 657-672 2022
• N Engl J Med
  Schwartz GG, Steg PG, , Zeiher AM. Agarwal H , et al. Alirocumab and Cardiovascular Outcomes after Acute Coronary Syndrome. N Engl J Med. 2018 Nov 29;379(22):2097-2107 2021
• Lancet Diabetes Endocrinol
  Lipoprotein(a) and Benefit of PCSK9 Inhibition in Patients With Nominally Controlled LDL Cholesterol J Am Coll Cardiol 2021 Aug 3;78(5):421-433. Gregory G Schwartz 1 , Michael Szarek 2 , Vera A Bittner, H. Agarwal et al. ODYSSEY Outcomes Committees and Investigators. 2021
• Journal of American College of Cardiology
  Predictors of Device-Related Thrombus Following Percutaneous Left Atrial Appendage Occlusion: Simard T, Jung , Alkhouli M, Agarwal H et.al Journal of American College of Cardiology ; Volume 78, Issue 4Pages A1-A36, e19-e24, 297-420, (27 July 2021 2021
• Diabetes Care
  Relation of Lipoprotein(a) Levels to Incident Type 2 Diabetes and Modification by Alirocumab Treatment. Schwartz GG, Szarek M, Bittner VA, Bhatt DL, Diaz R, Goodman SG, Jukema JW, Loy M, Manvelian G, Pordy R, White HD, Steg PG; ODYSSEY OUTCOMES Committees and Investigators. Diabetes Care. 2021 May;44(5):1219-1227. 10.2337/dc20-2842 2021
• JACC Case Report
  Left Atrial Appendage Closure in a Patient With a Patent Foramen Ovale Septal Occluder Device Omar Kousa 1 , Toufik Mahfood-Haddad 1 , Shantanu M Patil 1 , Himanshu Agarwal 1 , Hussam Abuissa ACC Case Rep 2021 Mar 17;3(3):508-511 2021
• Heart Rhythm Case Reports
  Left atrial appendage closure in a patient with situs inversus totalis and interrupted inferior vena cava - A transhepatic approach.Tandon TS, Agarwal H, Alla VM, Abuissa HS. HeartRhythm Case Rep. 2020 Sep 15;6(11):871-874. 2020
• J American College of Cardiology Cardiovascular Interv
  Van Mieghem NM, Popma JJ, Reardon M, Agarwal, H et al . Complete 2-Year Results Confirm Bayesian Analysis of the SURTAVI Trial. JACC Cardiovasc Interv2020 Feb 10;13(3):323-33 2020
• Lancet Diabetes Endocrinol
  Ray KK, Colhoun HM, Szarek M, Steg PG, Agarwal H et al. Effects of alirocumab on cardiovascular and metabolic outcomes after acute coronary syndrome in patients with or without diabetes: a prespecified analysis of the ODYSSEY OUTCOMES randomised controlled trial. Lancet Diabetes Endocrinol. 2019 Aug;7(8):618-628 2019
• J American College of Cardiology Cardiovascular Interv
  Massive Inferior Vena Cava Thrombosis Associated With Retroperitoneal Venolymphatic Malformation Raviteja R. Guddeti, Geetanjali Dang MD, Abilash AkinapelliMD, Himanshu AgarwalMD and Joseph StavasMD J Am Coll Cardiol Cardiovasc Interv. 2018 Nov, 11 (22) e187–e188. 2018
• J Am Coll Cardiol
  Outcomes of Drug-Eluting versus Bare-Metal Stents in Saphenous Vein Graft Lesions: A Meta-Analysis of Randomized Controlled Trials Toufik Mahfood Haddad, Aravdeep Jhand, Jai Parekh, Luay Sarsam, Abdul Saadi, Aiman Smer, Himanshu Agarwal, Michael Delcore and Venkata M. Alla. J Am Coll Cardiol. 2018 Sep, 72 (13_Supplement) B112 2018
• N Engl J Med
  Reardon MJ, Van Mieghem NM, , Kappetein AP Agarwal H; .et.al. Surgical or Transcatheter Aortic-Valve Replacement in Intermediate-Risk Patients. Second Generation Versus First Generation Transcatheter Aortic Valve Replacement: A Meta-analysis :N Engl J Med. 2017 Apr 6;376(14):1321-1331 2017
• J Am Coll Cardiol
  Arun Kanmanthareddy, Dixitha Anugula, Sameer Gafoor, Rahul Sharma, Claire Hunter, Scott Lilly, Michael White, Michael Del Core, Himanshu Agarwal, Dennis Esterbrooks, Aryan Mooss and Venkata Alla. J Am Coll Cardiol Cardiovasc Interv. 2017 Feb, 10 (3_Supplement) S71 2017
• JAMA: Journal of the American Medical Association
  Yeh RW, Shlofmitz R, Moses J, Bachinsky W, Dohad S, Rudick S, Stoler R, Jefferson BK, Nicholson W, Altman J, Bateman C, Krishnaswamy A, Grantham JA, Zidar FJ, Marso SP, Tremmel JA, Grines C, Ahmed MI, Latib A, Tehrani B, Abbott JD, Batchelor W, Underwood P, Allocco DJ, Kirtane AJ Paclitaxel-Coated Balloon vs Uncoated Balloon for Coronary In-Stent Restenosis: The AGENT IDE Randomized Clinical Trial. Yeh RW, Shlofmitz R, Moses J, Bachinsky W, Dohad S, Rudick S, Stoler R, Jefferson BK, Nicholson W, Altman J, Bateman C, Krishnaswamy A, Grantham JA, Zidar FJ, Marso SP, Tremmel JA, Grines C, Ahmed MI, Latib A, Tehrani B, Abbott JD, Batchelor W, Underwood P, Allocco DJ, Kirtane AJ AGENT IDE Investigators. JAMA. 2024 Mar 26;331(12):1015-1024. doi: 10.1001/jama.2024.1361.PMID: 3846016 0024
• J Am Coll Cardiol
  Van Mieghem, N, Deeb, G.M.; Sondergaard, L; Agarwal, H Self -expanding Transcatheter vs Surgical AVR in Intermediate risk patients:5 year outcomes of the SURTAVI Randomized Clinical trial Nicolas M. Van Mieghem, MD, ; G. Michael Deeb, MD, Lars Søndergaard, MD, PhD,Agarwal H; et al JAMA Cardiol. 2022;7(10):1000-1008. doi:10.1001/jamacardio.2022.2695
  7, p. 1000-1008 -0001