Schuyler Chambers, PhD

Research Focus

Research in the Chambers Lab harnesses synthetic carbohydrate chemistry to interrogate the biology of bacterial communities and bacterial polysaccharides. Broadly, the research program has two major facets: 1) the design and synthesis of carbohydrate-based tools to study glycobiology and antimicrobial resistance, and 2) the development of non-perturbative biochemical isolation methods to characterize unknown bacterial polysaccharides and biopolymers. Our research reveals the structural composition of biofilm communities and extracellular polysaccharides produced by pathogenic microbes, so that we can better translate our chemical understanding of these biopolymers into the design and synthesis of drug-delivery agents and antibiotic adjuvants to combat antibiotic resistant infections.