Laura A . Hansen

Professor

Professor

L Hansen

Contact

School of Medicine
Biomedical Sciences
Graduate School
Biomedical Sciences (Master of Science)
Biomedical Sciences (Doctorate)
SOM Leadership
Lynch Cancer Research Center
Research - Medicine
CRISS II - Criss 2 - 431

Laura A . Hansen

Professor

Professor

Cancer Research Focus

The long-term objective of Dr. Hansen’s research is to develop new clinically-useful, mechanism-based approaches the prevention and treatment of skin cancer. Current research projects are focused on dysregulation of checkpoint signaling pathways to suppress apoptosis and cell competition through Flower signaling in skin cancer.    

Cancer Research Area(s)
  • Brain Cancer
  • Head and Neck Cancer
  • Skin Cancer

Research Focus

The long-term objective of Dr. Hansen’s research is to develop new clinically-useful, mechanism-based approaches the prevention and treatment of skin cancer. Research in the Hansen lab revolves around the question, “How do environmental exposures reprogram molecular pathways to lead to cancer and how does this provide novel targets for cancer treatment or prevention?” Current research projects are focused on dysregulation of checkpoint signaling pathways to suppress apoptosis, novel estrogen receptor signaling, and cell competition through Flower signaling in skin cancer.    

Department

Biomedical Sciences

Position

Professor

Books

  • Reference Module in Biomedical Sciences
    Hansen Laura A., Squamous Cell Carcinoma of the Skin [Book Chapter] 2015
  • Reference Module in Biomedical Sciences
    Hansen Laura A., Basal Cell Carcinoma [Book Chapter] 2015
  • Reference Module in Biomedical Research
    Hansen Laura A., Mycosis Fungoides [Book Chapter] 2014
  • Reference Module in Biomedical Research
    Hansen Laura A., Melanoma [Book Chapter] 2014
  • xPharm: The Comprehensive Pharmacology Reference
    Hansen Laura A., Mycosis Fungoides [Book Chapter] 2011
  • xPharm: The Comprehensive Pharmacology Reference
    Hansen Laura A., Skin Cancer [Book Chapter] 2011
  • xPharm: The Comprehensive Pharmacology Reference
    Hansen Laura A., Melanoma [Book Chapter] 2011
  • xPharm: The Comprehensive Pharmacology Reference
    Hansen Laura A., Basal Cell Carcinoma [Book Chapter] 2011
  • xPharm: The Comprehensive Pharmacology Reference
    Hansen Laura A., Squamous Cell Carcinoma [Book Chapter] 2011
  • Signaling Pathways in Squamous Cancer
    Repertinger Susan K., Hansen Laura A., Madson Justin G., Bichsel Kyle J., The Epidermal Growth Factor Receptor in Normal and Neoplastic Epithelia [Book Chapter] 2011

Publications

  • Nature communications
    Rudd Justin C., Grunkemeyer James A., Madson Justin G., Sarkar Mrinal K., van den Bogaard Ellen H., Gudjonsson Johann E., van Vlijmen-Willems Ivonne M. J. J., Wong Sunny Y., Simpson Cory L., Hansen Laura A., Smits Jos P. H., Kuwong Patrick T., Johnson Rachel E., Monga Louise M. N., Porter Greer L., Kumar Vikas, Halloran Peter O., Sharma Kanika, Schmidt Karina N., Flower dependent trafficking of lamellar bodies facilitates maturation of the epidermal barrier
    16:1, p. 6892 2025
  • FEBS letters
    Kamayirese Seraphine, Hansen Laura A., Lovas Sándor, Ligand recognition by 14‐3‐3 proteins requires negative charges but not necessarily phosphorylation 2025
  • Molecular biology reports
    Agrawal Swati, Podber Anna, Nandipati Kalyana C., Hansen Laura A., Gillespie Megan, Dietz Nick, Regulation of pro-apoptotic and anti-apoptotic factors in obesity-related esophageal adenocarcinoma
    51:1, p. 1049 2024
  • Biomarker research
    Fu Yusi, Yin Shiwei, Agrawal Swati, Snyder Daniel R., Zhong Na, Grunkemeyer James A., Waddah Al-Refaie, Dietz Nicholas, Corlett Ryan, Hansen Laura A., Nandipati Kalyana C., Xia Jun, Transcriptomic changes and gene fusions during the progression from Barrett’s esophagus to esophageal adenocarcinoma
    12:1, p. 78 2024
  • The Journal of pharmacology and experimental therapeutics
    Opere Catherine, Mhatre Susmit, Rai Anjali, Hansen Laura, Borgmeier John, Howe Christina, Grunkemeyer James, Mbye Ya Fatou Njie, Ohia Sunny, Singh Somnath, Regulation of IOP and Retinal Degeneration by GYY 4137 in Carbomer-Induced OHT Rabbits, In vivo
    389, p. 530 - 530 2024
  • International journal of molecular sciences
    Kamayirese Seraphine, Maity Sibaprasad, Hansen Laura A, Lovas Sándor, The Development of CDC25A-Derived Phosphoseryl Peptides That Bind 14-3-3ε with High Affinities
    25:9, p. 4918 2024
  • ACS omega
    Kamayirese Seraphine, Dieckman Lynne M., Hansen Laura A., Lovas Sándor, Maity Sibaprasad, Optimizing Phosphopeptide Structures That Target 14-3-3ε in Cutaneous Squamous Cell Carcinoma 2024
  • The Journal of biological chemistry
    Rudd Justin C., Maity Sibaprasad, Grunkemeyer James A., Snyder Joshua C., Lovas Sándor, Hansen Laura A., Membrane structure and internalization dynamics of human Flower isoforms hFWE3 and hFWE4 indicate a conserved endocytic role for hFWE4, p. 104945 - 104945 2023
  • Journal of clinical oncology
    Rana Ricky, Hansen Laura A., Targeting Exportin 1 as treatment for cutaneous squamous cell carcinoma
    41:16_suppl, p. e21564 - e21564 2023
  • The Journal of biological chemistry
    Rudd Justin, Maity Sibaprasad, Snyder Joshua, Lovas Sandor, Hansen Laura, Abstract 1432: Structural determination and internalization dynamics of human Flower isoforms
    299:3, p. 103795 2023
  • Biophysical journal
    Nichols Michael G., Farr Tyler B., Hubbs Hayden M., Kalhorn Connor J., Myers Cecilia M., Nguyen Alicia C., Rogers Samuel J., Snyder Dan R., Tran Thien, Varghese George J., Wood Daniel, Pham Dan L., Hansen Laura A., Impact of cell culture conditions on assessment of cellular metabolism in vitro by NAD(P)H phasor flim with application to in vivo diagnostic imaging for non-invasive biopsy
    121:3, p. 276a - 276a 2022
  • Journal of Biomedical Optics
    Pham Dan L., Miller Christina R., Myers Molly S., Myers Dominick M., Hansen Laura A., Nichols Michael G., Development and characterization of phasor-based analysis for FLIM to evaluate the metabolic and epigenetic impact of HER2 inhibition on squamous cell carcinoma cultures
    26:10 2021
  • Journal of biomedical optics
    Pham Dan L, Miller Christina R, Myers Molly S, Myers Dominick M, Hansen Laura A, Nichols Michael G, Development and characterization of phasor-based analysis for FLIM to evaluate the metabolic and epigenetic impact of HER2 inhibition on Squamous Cell Carcinoma (SCC) cultures
    26:10 2021
  • Carcinogenesis
    Holmes Thomas R., Palermo Nicholas Y., Rudd Justin C., Bloom Celia, Nicola Lauren, Madson Justin G., Al Matouq Jenan, Holmes Matti, Sioda Natasha, Lovas Sándor, Hansen Laura A., Targeting 14-3-3ϵ activates apoptotic signaling to prevent cutaneous squamous cell carcinoma
    42:2, p. 232 - 242 2021
  • Oncotarget
    Holmes Thomas R., Al-Matouq Jenan, Holmes Matti, Nicola Lauren, Rudd Justin C., Lovas Sándor, Hansen Laura A., Targeting 14-3-3ε-CDC25A interactions to trigger apoptotic cell death in skin cancer
    11:35, p. 3267 - 3278 2020
  • Journal of Dermatological Science
    Lobl Marissa B., Clarey Dillon, Higgins Shauna, Sutton Adam, Hansen Laura, Wysong Ashley, Targeted next-generation sequencing of matched localized and metastatic primary high-risk SCCs identifies driver and co-occurring mutations and novel therapeutic targets
    99:1, p. 30 - 43 2020
  • Biophysical journal
    Nichols Michael G., Huerter Ben G., Myers Molly, Myers Dominick, Jackson Kelsey A., Che Dan L., Altuzar Emiliano, Long Anya, Morris Jackson W., Hansen Laura A., Nguyen Duyen, Kalhorn Connor J., Varghese George, Sotelo Katie D., Frances Gabriel Marifel, Phasor-FLIM Quantification of Changes in Keratinocyte Metabolism and Tissue Architecture in a Longitudinal Study of UV-induced Skin Cancer
    118:3, p. 307a - 307a 2020
  • Molecular Carcinogenesis
    Holmes Thomas R., Dindu Shravya, Hansen Laura A., Aberrant localization of signaling proteins in skin cancer
    58:9, p. 1631 - 1639 2019
  • Molecular Carcinogenesis
    Al-Matouq Jenan, Holmes Thomas R., Hansen Laura A., CDC25B and CDC25C overexpression in nonmelanoma skin cancer suppresses cell death
    58:9, p. 1691 - 1700 2019
  • Nature
    Madan Esha, Moreno Eduardo, Fazio Kimberly, Pelham Christopher J., Nagane Masaki, Parker Taylor M., Canas-Marques Rita, Shaik Kranti, Yuan Youzhong, Henriques Vanessa, Galzerano Antonio, Pinto Miguel Alexandre Ferreira, Yamashita Tadashi, Palma Antonio M., Camacho Denise, Vieira Ana, Soldini David, Nakshatri Harikrishna, Post Steven R., Hansen Laura A., Rhiner Christa, Yamashita Hiroko, Accardi Davide, Carvalho Carlos, Beltran Antonio L., Kuppusamy Periannan, Gogna Rajan, Flower isoforms promote competitive growth in cancer
    572:7768, p. 260 - 264 2019
  • Biophysical journal
    Myers Dominick, Huerter Ben G., Che Dan L., Myers Molly, Nguyen Duyen, Hansen Laura A., Nichols Michael G., Yang Brooke L., Frances Gabriel Marifel, Jackson Kelsey A., Sotelo Katie D., Two-Photon Imaging of NADH in SKH1 Mice Reveals Changes in Keratinocyte Metabolism with Chronic UVA Exposure
    116:3, p. 281a - 282a 2019
  • Cancer research (Chicago, Ill.)
    Holmes Thomas R., Nicholson Yawah T., Al-Matouq Jenan, Hammiller Brianna, Holmes Matti J., Hansen Laura A., Abstract LB-190: CDC25A suppression of apoptosis in cutaneous squamous cell carcinoma depends on 14-3-3ϵ
    78:13_Supplement, p. LB-190 - LB-190 2018
  • Journal of Biological Chemistry
    Madan Esha, Holmes Matti, Pelham Christopher J., Nagane Masaki, Lakshmi Kuppusamy M., Holmes Thomas R., Shaik Kranti, Shee Kevin, Kiparoidze Salome, Smith Sean D., Park Yu Soon A., Gomm Jennifer J., Jones Louise J., Tomás Ana R., Hideg Kálmán, Gogna Rajan, Kuppusamy Periannan, Fersht Alan R., Cunha Ana C., Selvendiran Karuppaiyah, Hansen Laura A., Dhiman Alisha, Parker Taylor M., Bauer Matthias R., The curcumin analog HO-3867 selectively kills cancer cells by converting mutant p53 protein to transcriptionally active wildtype p53
    293:12, p. 4262 - 4276 2018
  • Experimental Dermatology
    Bichsel Kyle J., Li Y., Hansen Laura A., Hammiller Brianna O., Trempus C. S., The Epidermal Growth Factor Receptor Decreases Stathmin 1 and Triggers Catagen Entry in the Mouse
    25:4, p. 275 - 281 2016
  • Molecular Carcinogenesis
    Rao Velidi H., Yanagida Jodi K., Vogel Kristen, Marwaha Nitin, Kandel Amrit, Trempus C., Repertinger Susan K., Hansen Laura A., Erbb2 up-regulation of ADAM12 expression accelerates skin cancer progression
    54:10, p. 1026 - 1036 2015
  • Frontiers in Oncology
    Hammiller Brianna O., El-Abaseri Taghrid B., Dlugosz A. A., Hansen Laura A., A Method for the Immortalization of Newborn Mouse Skin Keratinocytes
    5, p. (9 pages) 2015
  • Journal of Dermatological Science
    Shirley Stephanie H., Hammiller Brianna O., Hudson Laurie G., Kusewitt Donna F., Crysup Benjamin, Hansen Laura A., Role of the Epidermal Growth Factor Receptor in Ultraviolet Radiation Induction of Snail Family Transcription Factors
    76:2, p. 149 - 151 2014
  • Cancer research (Chicago, Ill.)
    Almatouq Jenan, Ho Kristen, Hansen Laura A., Abstract 1310: Increased cytoplasmic CDC25A phosphatase in cutaneous squamous cell carcinoma leads to 14-3-3 relocalization and suppression of apoptosis
    74:19_Supplement, p. 1310 - 1310 2014
  • Molecular Carcinogenesis
    Rao Velidi H., Marwaha Nitin, Vogel Kristen, Yanagida Jodi K., Kandel Amrit, Trempus Carol, Repertinger Susan K., Hansen Laura A., Erbb2 up-regulation of ADAM12 expression accelerates skin cancer progression
    ePub ahead of print, p. 11 pages 2014
  • PloS one
    Bichsel Kyle J., Pena Zachary, Gogia Navdeep, Malouff Timothy, Forney Eric, Hammiller Brianna, Watson Patrice, Hansen Laura A., Role for the Epidermal Growth Factor Receptor in Chemotherapy-Induced Alopecia
    8:7, p. 1 - 12 2013
  • ISRN Dermatology
    El-Abaseri Taghrid Bahig, Hansen Laura A., Hammiller Brianna, Repertinger Susan K., The Epidermal Growth Factor Receptor Increases Cytokine Production and Cutaneous Inflammation in Response to Ultraviolet Irradiation
    2013, p. 1 - 11 2013
  • Cancer research (Chicago, Ill.)
    Bichsel Kyle J., Hansen Laura A., Foote Courtney, Gaulter Jessica A., Porto Dennis, Abstract 1219: Defective catagen entry in EGFR deficient skin precedes cutaneous inflammation
    72:8_Supplement, p. 1219 - 1219 2012
  • Carcinogenesis
    Yanagida J., Behrens M., Hammiller B., Al-Matouq J., Trempus C. S., Repertinger Susan K., Hansen Laura A., Accelerated elimination of ultraviolet-induced DNA damage through apoptosis in CDC25A deficient skin
    33:9, p. 1754 - 1761 2012
  • Oncogene
    Rao Velidi H., Deng Cai-Shu, Lynch David T., Pena Zachary G., Marwaha Nitin, Watson Patrice, Kandel Amrit, Hansen Laura A., A positive feedback loop between HER2 and ADAM12 in human head and neck cancer cells increases migration and invasion
    31:23, p. 2888 - 2898 2012
  • The FASEB journal
    Trotter Caitlyn, Maklad Adel, Hansen Laura, Conway Marianne, Evidence for critical period in development of cutaneous innervation: A study in nude mice
    25:S1, p. lb29 - lb29 2011
  • Anatomical Record
    Maklad Adel, Conway Marianne, Hodges Cole, Hansen Laura A., Development of innervation to maxillary whiskers in mice
    293:9, p. 1553 - 1567 2010
  • Molecular Carcinogenesis
    Virador Victoria M., Patel Rinal, Strain Kathryn, Anders Joanna, Cataisson Christophe, Hansen Laura A., Yuspa Stuart H., Flores-Obando Rafael E., Berry Adam, Zakhari Julia, Lo Yu Chien, The human promyelocytic leukemia protein is a tumor suppressor for murine skin carcinogenesis
    48:7, p. 599 - 609 2009
  • Molecular Carcinogenesis
    Virador Victoria M., Patel Rinal, Flores-Obando Rafael E., Berry Adam, Zakhari Julia, Lo Yu-Chien, Strain Kathryn, Hansen Laura A., Yuspa Stuart H., Cataisson Christophe, Anders Joanna, The Human Promyelocytic Leukemia Protein Is a Tumor Suppressor for Murine Skin Carcinogenesis
    48:7, p. 599 - 609 2009
  • American Journal of Pathology
    Madson Justin G., Ophardt Rebecca, Tennant Raymond W., Hansen Laura A., Bowles Andrew, Trempus Carol S., Lynch David T., Svoboda Jessica, Putta Sumanth K., Yanagida Jodi, Erbb2 Suppresses DNA Damage-Induced Checkpoint Activation and UV-Induced Mouse Skin Tumorigenesis
    174:6, p. 2357 - 2366 2009
  • Journal of Investigative Dermatology
    Maklad Adel, Evenson Jackie E., Nicolai Jodi R., Bichsel Kyle J., Lee Tang-Cheng, Threadgill David W., Hansen Laura A., The EGFR Is Required for Proper Innervation to the Skin
    129:3, p. 690 - 698 2009
  • Cell and Tissue Research
    Beisel Kirk W., Hansen Laura A., Soukup Garrett A., Fritzsch Bernd, Regenerating cochlear hair cells: quo vadis stem cell
    333:3, p. 373 - 379 2008
  • Toxicologic pathology
    Lynch Dave, Hofland Hans E.J., Svoboda Jessica, Putta Sumanth, Chern Wendy H., Hansen Laura A., Mouse skin models for carcinogenic hazard identification
    35:7, p. 853 - 864 2007
  • Molecular Carcinogenesis
    Madson J. G., Hansen Laura A., Multiple mechanisms of Erbb2 action after ultraviolet irradiation of the skin
    46:8, p. 624 - 628 2007
  • Pediatric Dermatology
    Hornung R. L., Lipsky M. S., Hansen Laura A., Sharp L. K., Poorsattar S. P., Skin cancer prevention in the primary care setting: assessment using a standardized patient
    24:2, p. 108 - 112 2007
  • Journal of Biomedicine and Biotechnology
    El-Abaseri Taghrid B., Hansen Laura A., EGFR activation and ultraviolet light-induced skin carcinogenesis, p. 97939 2007
  • Toxicologic Pathology
    Lynch Dave, Svoboda Jessica, Putta Sumanth, Hofland Hans E. J., Chern Wendy H., Hansen Laura A., Mouse skin models for carcinogenic hazard identification: utilities and challenges
    35:7, p. 853 - 864 2007
  • BioEssays
    Fritzsch Bernd, Beisel Kirk W., Hansen Laura A., The molecular basis of neurosensory cell formation in ear development: a blueprint for hair cell and sensory neuron regeneration?
    28:12, p. 1181 - 1193 2006
  • American Journal of Pathology
    Madson Justin G., Putta Sumanth K., Lynch David T., Tinkum Kelsy L., Hansen Laura A., Erbb2 regulates inflammation and proliferation in the skin after ultraviolet irradiation
    169:4, p. 1402 - 1414 2006
  • Brain Research
    Morris Jacqueline K., Sorensen Christian, Lee Kuo Fen, Macklin Wendy B., Fritzsch Bernd, Maklad Adel, Hansen Laura A., Feng Feng, A disorganized innervation of the inner ear persists in the absence of ErbB2
    1091:1, p. 186 - 199 2006
  • Carcinogenesis
    El-Abaseri Taghrid B., Putta Sumanth K., Hansen Laura A., Ultraviolet irradiation induces keratinocyte proliferation and epidermal hyperplasia through the activation of the epidermal growth factor receptor
    27:2, p. 225 - 231 2006
  • Journal of Investigative Dermatology
    Khan Gausal A., Meza Jane L., Chakravarti Dhrubajyoti, Bhattacharya Gautam, Mailander Paula C., Hansen Laura A., Harvey-ras gene expression and epidermal cell proliferation in dibenzo[a,I]pyrene-treated early preneoplastic SENCAR mouse skin
    125:3, p. 567 - 574 2005
  • Lung cancer (Amsterdam, Netherlands)
    Jensen R., Spang-Thomsen M., Hansen L., P-057 Expression of the cyclin-dependent kinase inhibitor p21 is linkedto regulation of RAD51 in response to etoposide treatment of small cell lung cancer cells
    49, p. S129 - S129 2005
  • Cancer Research
    El-Abaseri Taghrid B., Tennant R. W., Hansen Laura A., Fuhrman Jill, Trempus C., Shendrik I., Chemoprevention of UV light-induced skin tumorigenesis by inhibition of the epidermal growth factor receptor.
    65:9, p. 3958 - 3965 2005
  • Toxicologic pathology
    Fuhrman Jill, Hansen Laura A., Shafer Laura, Repertinger Susan, Chan Tom, Mechanisms of SEPA 0009-induced tumorigenesis in v-rasHa transgenic Tg.AC mice.
    33:6, p. 623 - 630 2005
  • Journal of Investigative Dermatology
    Repertinger Susan K., Hansen Laura A., Yuspa S. H., Campagnaro E., Fuhrman Jill, El-Abaseri Taghrid B., EGFR enhances early healing after cutaneous incisional wounding
    123:5, p. 982 - 989 2004
  • Pharmacotherapy
    Snella Kathleen A., Trewyn Rence R., Hansen Laura A., Bradberry J. Chris, Pharmacist Compensation for Cognitive Services: Focus on the Physician Office and Community Pharmacy
    24:3, p. 372 - 388 2004
  • Journal of Biological Chemistry
    Wei Sung Jen, Trempus Carol S., Ali Robin C., Hansen Laura A., Tennant Raymond W., 12-O-Tetradecanoylphorbol-13-acetate and UV Radiation-induced Nucleoside Diphosphate Protein Kinase B Mediates Neoplastic Transformation of Epidermal Cells
    279:7, p. 5993 - 6004 2004
  • Cell and Tissue Research
    Maklad Adel, Fritzsch Bernd, Hansen Laura A., Innervation of the maxillary vibrissae in mice as revealed by anterograde and retrograde tract tracing
    315:2, p. 167 - 180 2004
  • Cancer Research
    Hansen Laura A., Riley Rebeccah, Brown Diane, Virador Victoria, Strain Kathryn, Dancheck Barbara, Arbeit Jeffrey M., De Luca Luigi M., Kogan Scott, Yuspa Stuart H., Tanaka Takemi, Andreola Fausto, A PMLRARA transgene results in a retinoid-deficient phenotype associated with enhanced susceptibility to skin tumorigenesis
    63:17, p. 5257 - 5265 2003
  • Cancer Research
    Hansen Laura A., Brown D., Strain K., Virador V., Tanaka T., Andreola F., Dancheck B., Riley R., Arbeit J. M., De Luca L. M., Yuspa S. H., Kogan S., A PMLRARA transgene results in a retinoid-deficient phenotype associated with enhanced susceptibility to skin tumorigenesis
    63:17, p. 5257 - 5265 2003
  • Oncogene
    Seker Hasan, Bowman Elise D., Rubbi Carlos, Linke Steven P., Garfield Susan, Hansen Laura, Borden Katherine L.B., Milner Jo, Harris Curtis C., UV-C-induced DNA damage leads to p53-dependent nuclear trafficking of PML
    22:11, p. 1620 - 1628 2003
  • Cancer Research
    Hansen Laura A., Strain Kathryn, Woodson Roderick L., Holbus Sherry, Lo You Chein, Yuspa Stuart H., The epidermal growth factor receptor is required to maintain the proliferative population in the basal compartment of epidermal tumors
    60:13, p. 3328 - 3332 2000
  • Cancer research
    Hansen L A, Holbus S, Woodson R L, Strain K, Lo Y C, Yuspa S H, The epidermal growth factor receptor is required to maintain the proliferative population in the basal compartment of epidermal tumors
    60:13, p. 3328 - 3332 2000
  • Carcinogenesis
    Hansen Laura A., Ross Sharon A., Sigman Caroline C., Andreola Fausto, Kelloff Gary J., De Luca Luigi M., Retinoids in chemoprevention and differentiation therapy
    21:7, p. 1271 - 1279 2000
  • Carcinogenesis
    Hansen Laura A., Rosenberg Michael, Malarkey David E., Wilkinson J. Erby, Woychik Richard E., Tennant Raymond W., Effect of the viable-yellow (A(vy)) agouti allele on skin tumorigenesis and humoral hypercalcemia in v-Ha-ras transgenic TG.AC mice
    19:10, p. 1837 - 1845 1998
  • Cancer Research
    Tennenbaum Tamar, Gartsbein Marina, Hansen Laura, Lowry David, Darwiche Nadine, Morgan David L., De Luca Luigi M., Hennings Henry, Yuspa Stuart H., Topical retinoic acid reduces skin papilloma formation but resistant papillomas are at high risk for malignant conversion
    58:7, p. 1435 - 1443 1998
  • Toxicologic pathology
    Humble Michael C., Spalding Judson W., Szczesniak Carl J., Luetteke Noreen C., Cannon Ronald E., Hansen Laura A., Lee David C., Tennant Raymond W., TGFα is dispensable for skin tumorigenesis in Tg.AC mice
    26:4, p. 562 - 569 1998
  • American Journal of Pathology
    Hansen Laura A., Sundberg John P., Alexander Natalie, Hogan Margaret E., Dlugosz Andrzej, Threadgill David W., Magnuson Terry, Yuspa Stuart H., Genetically null mice reveal a central role for epidermal growth factor receptor in the differentiation of the hair follicle and normal hair development
    150:6, p. 1959 - 1975 1997
  • Carcinogenesis
    Hansen Laura A., Tennant Raymond W., Trempus Carol S., Mahler Joel F., Association of tumor development with increased cellular proliferation and transgene overexpression, but not c-Ha-ras mutations, in v-Ha-ras transgenic Tg.AC mice
    17:9, p. 1825 - 1833 1996
  • Archives of Oral Biology
    Wright J. T., Spalding J. W., Hansen L., Mahler J., Szczesniak C., Odontogenic tumours in the v-Ha-ras (TG · AC) transgenic mouse
    40:7, p. 631 - 638 1995
  • Progress in clinical and biological research
    Hansen L. A., Tennant R. W., Spalding J. W., French J. E., A transgenic mouse model (TG.AC) for skin carcinogenesis
    391, p. 223 - 235 1995
  • Molecular Carcinogenesis
    French John E., Mahler Joel, Libbus Bisharah L., Hansen Laura, Spalding Judson, Tice Raymond R., Tennant Raymond W., Cytogenetic analysis of malignant skin tumors induced in chemically treated TG.AC transgenic mice
    11:4, p. 215 - 226 1994
  • Proceedings of the National Academy of Sciences of the United States of America
    Hansen Laura A., Tennant Raymond W., Follicular origin of epidermal papillomas in v-Ha-ras transgenic TG.AC mouse skin
    91:16, p. 7822 - 7826 1994
  • Mutagenesis
    Tennant Raymond W., Hansen Laura, Spalding Judson, Gene manipulation and genetic toxicology
    9:3, p. 171 - 174 1994
  • Molecular Carcinogenesis
    Hansen Laura A., Tennant Raymond, Focal transgene expression associated with papilloma development in v‐Ha‐ras–transgenic TG.AC mice
    9:3, p. 143 - 154 1994
  • Cancer genetics and cytogenetics
    Libbus Bisharah L., Tennant Raymond W., French John E., Spalding Judson, Hansen Laura, Tice Raymond R., Highly repetitive chromosome changes associated with skin tumor development in transgenic mice treated with TPA
    66:2, p. 152 - 152 1993
  • Breast cancer research and treatment
    SPANG-THOMSEN M, Vindeløv L. L, Rygaard K, Hansen L, Halvorsen A.-C, Brunner N, Growth kinetics of four human breast carcinomas grown in nude mice
    14:2, p. 235 - 243 1989
  • Cancer Research
    Smart Robert C., Hansen Laura A., Conney Allan H., Mills Kevin J., Synthetic Lipid Second Messenger sn-1,2-Didecanoylglycerol
    49:16, p. 4455 - 4458 1989
  • Water, Air, and Soil Pollution
    Hansen Laura A., A method for chemical fractionation of chloride from complex effluents
    42:3-4, p. 259 - 265 1988

Awards

  • Dr. Robert Heaney Graduate Research Mentor Award
    Creighton University
  • 1st place Graduate Student Platform Presentation by student Justin Rudd
    1st place Graduate Student Platform Presentation by student Justin Rudd in Basic Sciences during University Research Week
  • University Research Award
    Creighton University
  • First Place Prize for Graduate Student Poster
    Awarded to my advisee Matti Holmes for her research performed in my lab
    Creighton University Research Day
  • Third place prive for poster presentation by medical student and mentee Timothy Malouff at the Midwest Biomedical Student Research Forum
    Third place prive for poster presentation by medical student and mentee Timothy Malouff at the Midwest Biomedical Student Research Forum
  • Third place poster awarded to my Ph.D. student Justin Madson at the Midwest Biomedical Student Research Forum
    Third place poster awarded to my Ph.D. student Justin Madson at the Midwest Biomedical Student Research Forum
  • Society of Investigative Dermatology Eugene M. Farber Endowment Award
    Society of Investigative Dermatology Eugene M. Farber Endowment Award

Consulting

  • Protransit Nanotherapy, LLC External Advisory Board
    Board Member
    Protransit Nanotherapy
    2015 - 2015