Laura A . Hansen, PhD

Department

Biomedical Sciences

Position

Professor

Books

• Reference Module in Biomedical Sciences
  Hansen Laura A., Squamous Cell Carcinoma of the Skin [Book Chapter] 2015
• Reference Module in Biomedical Sciences
  Hansen Laura A., Basal Cell Carcinoma [Book Chapter] 2015
• Reference Module in Biomedical Research
  Hansen Laura A., Melanoma [Book Chapter] 2014
• Reference Module in Biomedical Research
  Hansen Laura A., Mycosis Fungoides [Book Chapter] 2014
• xPharm: The Comprehensive Pharmacology Reference
  Hansen Laura A., Skin Cancer [Book Chapter] 2011
• xPharm: The Comprehensive Pharmacology Reference
  Hansen Laura A., Mycosis Fungoides [Book Chapter] 2011
• xPharm: The Comprehensive Pharmacology Reference
  Hansen Laura A., Squamous Cell Carcinoma [Book Chapter] 2011
• xPharm: The Comprehensive Pharmacology Reference
  Hansen Laura A., Basal Cell Carcinoma [Book Chapter] 2011
• xPharm: The Comprehensive Pharmacology Reference
  Hansen Laura A., Melanoma [Book Chapter] 2011
• Signaling Pathways in Squamous Cancer
  Repertinger Susan K., Hansen Laura A., Madson Justin G., Bichsel Kyle J., The Epidermal Growth Factor Receptor in Normal and Neoplastic Epithelia [Book Chapter] 2011

Publications

• Nature communications
  Rudd Justin C., Madson Justin G., Sarkar Mrinal K., van den Bogaard Ellen H., Grunkemeyer James A., Gudjonsson Johann E., Wong Sunny Y., Simpson Cory L., Hansen Laura A., Smits Jos P. H., Kuwong Patrick T., Johnson Rachel E., Monga Louise M. N., van Vlijmen-Willems Ivonne M. J. J., Porter Greer L., Halloran Peter O., Sharma Kanika, Schmidt Karina N., Kumar Vikas, Flower dependent trafficking of lamellar bodies facilitates maturation of the epidermal barrier
  16:1, p. 6892 2025
• FEBS letters
  Kamayirese Seraphine, Hansen Laura A., Lovas Sándor, Ligand recognition by 14‐3‐3 proteins requires negative charges but not necessarily phosphorylation 2025
• Molecular biology reports
  Agrawal Swati, Hansen Laura A., Gillespie Megan, Dietz Nick, Podber Anna, Nandipati Kalyana C., Regulation of pro-apoptotic and anti-apoptotic factors in obesity-related esophageal adenocarcinoma
  51:1, p. 1049 2024
• Biomarker research
  Fu Yusi, Agrawal Swati, Snyder Daniel R., Yin Shiwei, Zhong Na, Grunkemeyer James A., Dietz Nicholas, Corlett Ryan, Hansen Laura A., Waddah Al-Refaie, Nandipati Kalyana C., Xia Jun, Transcriptomic changes and gene fusions during the progression from Barrett’s esophagus to esophageal adenocarcinoma
  12:1, p. 78 2024
• The Journal of pharmacology and experimental therapeutics
  Opere Catherine, Rai Anjali, Mhatre Susmit, Borgmeier John, Howe Christina, Grunkemeyer James, Hansen Laura, Mbye Ya Fatou Njie, Ohia Sunny, Singh Somnath, Regulation of IOP and Retinal Degeneration by GYY 4137 in Carbomer-Induced OHT Rabbits, In vivo
  389, p. 530 - 530 2024
• International journal of molecular sciences
  Kamayirese Seraphine, Maity Sibaprasad, Hansen Laura A, Lovas Sándor, The Development of CDC25A-Derived Phosphoseryl Peptides That Bind 14-3-3ε with High Affinities
  25:9, p. 4918 2024
• ACS omega
  Kamayirese Seraphine, Dieckman Lynne M., Hansen Laura A., Lovas Sándor, Maity Sibaprasad, Optimizing Phosphopeptide Structures That Target 14-3-3ε in Cutaneous Squamous Cell Carcinoma 2024
• The Journal of biological chemistry
  Rudd Justin C., Maity Sibaprasad, Grunkemeyer James A., Snyder Joshua C., Lovas Sándor, Hansen Laura A., Membrane structure and internalization dynamics of human Flower isoforms hFWE3 and hFWE4 indicate a conserved endocytic role for hFWE4, p. 104945 - 104945 2023
• Biophysical journal
  Nichols Michael G., Farr Tyler B., Hubbs Hayden M., Kalhorn Connor J., Myers Cecilia M., Nguyen Alicia C., Rogers Samuel J., Snyder Dan R., Tran Thien, Varghese George J., Wood Daniel, Pham Dan L., Hansen Laura A., Impact of cell culture conditions on assessment of cellular metabolism in vitro by NAD(P)H phasor flim with application to in vivo diagnostic imaging for non-invasive biopsy
  121:3, p. 276a - 276a 2022
• Journal of Biomedical Optics
  Pham Dan L., Miller Christina R., Myers Molly S., Myers Dominick M., Hansen Laura A., Nichols Michael G., Development and characterization of phasor-based analysis for FLIM to evaluate the metabolic and epigenetic impact of HER2 inhibition on squamous cell carcinoma cultures
  26:10 2021
• Journal of biomedical optics
  Pham Dan L, Miller Christina R, Myers Molly S, Myers Dominick M, Hansen Laura A, Nichols Michael G, Development and characterization of phasor-based analysis for FLIM to evaluate the metabolic and epigenetic impact of HER2 inhibition on Squamous Cell Carcinoma (SCC) cultures
  26:10 2021
• Carcinogenesis
  Holmes Thomas R., Rudd Justin C., Bloom Celia, Nicola Lauren, Palermo Nicholas Y., Madson Justin G., Lovas Sándor, Hansen Laura A., Al Matouq Jenan, Holmes Matti, Sioda Natasha, Targeting 14-3-3ϵ activates apoptotic signaling to prevent cutaneous squamous cell carcinoma
  42:2, p. 232 - 242 2021
• Oncotarget
  Holmes Thomas R., Al-Matouq Jenan, Holmes Matti, Nicola Lauren, Rudd Justin C., Lovas Sándor, Hansen Laura A., Targeting 14-3-3ε-CDC25A interactions to trigger apoptotic cell death in skin cancer
  11:35, p. 3267 - 3278 2020
• Journal of Dermatological Science
  Lobl Marissa B., Clarey Dillon, Higgins Shauna, Sutton Adam, Hansen Laura, Wysong Ashley, Targeted next-generation sequencing of matched localized and metastatic primary high-risk SCCs identifies driver and co-occurring mutations and novel therapeutic targets
  99:1, p. 30 - 43 2020
• Biophysical journal
  Nichols Michael G., Huerter Ben G., Myers Molly, Myers Dominick, Jackson Kelsey A., Che Dan L., Altuzar Emiliano, Long Anya, Morris Jackson W., Hansen Laura A., Nguyen Duyen, Kalhorn Connor J., Varghese George, Sotelo Katie D., Frances Gabriel Marifel, Phasor-FLIM Quantification of Changes in Keratinocyte Metabolism and Tissue Architecture in a Longitudinal Study of UV-induced Skin Cancer
  118:3, p. 307a - 307a 2020
• Molecular Carcinogenesis
  Al-Matouq Jenan, Holmes Thomas R., Hansen Laura A., CDC25B and CDC25C overexpression in nonmelanoma skin cancer suppresses cell death
  58:9, p. 1691 - 1700 2019
• Molecular Carcinogenesis
  Holmes Thomas R., Dindu Shravya, Hansen Laura A., Aberrant localization of signaling proteins in skin cancer
  58:9, p. 1631 - 1639 2019
• Nature
  Madan Esha, Moreno Eduardo, Pelham Christopher J., Nagane Masaki, Parker Taylor M., Canas-Marques Rita, Fazio Kimberly, Shaik Kranti, Yuan Youzhong, Henriques Vanessa, Galzerano Antonio, Yamashita Tadashi, Pinto Miguel Alexandre Ferreira, Palma Antonio M., Camacho Denise, Vieira Ana, Soldini David, Nakshatri Harikrishna, Post Steven R., Rhiner Christa, Yamashita Hiroko, Accardi Davide, Hansen Laura A., Carvalho Carlos, Beltran Antonio L., Kuppusamy Periannan, Gogna Rajan, Flower isoforms promote competitive growth in cancer
  572:7768, p. 260 - 264 2019
• Biophysical journal
  Myers Dominick, Huerter Ben G., Che Dan L., Myers Molly, Nguyen Duyen, Hansen Laura A., Nichols Michael G., Yang Brooke L., Frances Gabriel Marifel, Jackson Kelsey A., Sotelo Katie D., Two-Photon Imaging of NADH in SKH1 Mice Reveals Changes in Keratinocyte Metabolism with Chronic UVA Exposure
  116:3, p. 281a - 282a 2019
• Cancer research (Chicago, Ill.)
  Holmes Thomas R., Al-Matouq Jenan, Hammiller Brianna, Nicholson Yawah T., Holmes Matti J., Hansen Laura A., Abstract LB-190: CDC25A suppression of apoptosis in cutaneous squamous cell carcinoma depends on 14-3-3ϵ
  78:13_Supplement, p. LB-190 - LB-190 2018
• Journal of Biological Chemistry
  Madan Esha, Pelham Christopher J., Nagane Masaki, Lakshmi Kuppusamy M., Holmes Matti, Holmes Thomas R., Shaik Kranti, Shee Kevin, Kiparoidze Salome, Smith Sean D., Park Yu Soon A., Gomm Jennifer J., Jones Louise J., Tomás Ana R., Hideg Kálmán, Gogna Rajan, Kuppusamy Periannan, Cunha Ana C., Selvendiran Karuppaiyah, Hansen Laura A., Fersht Alan R., Parker Taylor M., Bauer Matthias R., Dhiman Alisha, The curcumin analog HO-3867 selectively kills cancer cells by converting mutant p53 protein to transcriptionally active wildtype p53
  293:12, p. 4262 - 4276 2018
• Cancer Letters
  Al-Matouq Jenan, Holmes Thomas, Hammiller Brianna, Tran Nicholas, Holmes Matti, Freeman S. Caleb, Hansen Laura A., Accumulation of cytoplasmic CDC25A in cutaneous squamous cell carcinoma leads to a dependency on CDC25A for cancer cell survival and tumor growth
  410, p. 41 - 49 2017
• Experimental Dermatology
  Bichsel Kyle J., Hansen Laura A., Hammiller Brianna O., Trempus C. S., Li Y., The Epidermal Growth Factor Receptor Decreases Stathmin 1 and Triggers Catagen Entry in the Mouse
  25:4, p. 275 - 281 2016
• Molecular Carcinogenesis
  Rao Velidi H., Vogel Kristen, Yanagida Jodi K., Marwaha Nitin, Kandel Amrit, Trempus C., Repertinger Susan K., Hansen Laura A., Erbb2 up-regulation of ADAM12 expression accelerates skin cancer progression
  54:10, p. 1026 - 1036 2015
• Frontiers in Oncology
  Hammiller Brianna O., El-Abaseri Taghrid B., Dlugosz A. A., Hansen Laura A., A Method for the Immortalization of Newborn Mouse Skin Keratinocytes
  5, p. (9 pages) 2015
• Journal of Dermatological Science
  Shirley Stephanie H., Hammiller Brianna O., Hudson Laurie G., Kusewitt Donna F., Hansen Laura A., Crysup Benjamin, Role of the Epidermal Growth Factor Receptor in Ultraviolet Radiation Induction of Snail Family Transcription Factors
  76:2, p. 149 - 151 2014
• Cancer research (Chicago, Ill.)
  Almatouq Jenan, Ho Kristen, Hansen Laura A., Abstract 1310: Increased cytoplasmic CDC25A phosphatase in cutaneous squamous cell carcinoma leads to 14-3-3 relocalization and suppression of apoptosis
  74:19_Supplement, p. 1310 - 1310 2014
• Molecular Carcinogenesis
  Rao Velidi H., Vogel Kristen, Yanagida Jodi K., Marwaha Nitin, Kandel Amrit, Trempus Carol, Repertinger Susan K., Hansen Laura A., Erbb2 up-regulation of ADAM12 expression accelerates skin cancer progression
  ePub ahead of print, p. 11 pages 2014
• PloS one
  Bichsel Kyle J., Gogia Navdeep, Malouff Timothy, Pena Zachary, Forney Eric, Hammiller Brianna, Watson Patrice, Hansen Laura A., Role for the Epidermal Growth Factor Receptor in Chemotherapy-Induced Alopecia
  8:7, p. 1 - 12 2013
• ISRN Dermatology
  El-Abaseri Taghrid Bahig, Hammiller Brianna, Repertinger Susan K., Hansen Laura A., The Epidermal Growth Factor Receptor Increases Cytokine Production and Cutaneous Inflammation in Response to Ultraviolet Irradiation
  2013, p. 1 - 11 2013
• Cancer research (Chicago, Ill.)
  Bichsel Kyle J., Hansen Laura A., Gaulter Jessica A., Porto Dennis, Foote Courtney, Abstract 1219: Defective catagen entry in EGFR deficient skin precedes cutaneous inflammation
  72:8_Supplement, p. 1219 - 1219 2012
• Oncogene
  Rao Velidi H., Lynch David T., Pena Zachary G., Marwaha Nitin, Deng Cai-Shu, Watson Patrice, Kandel Amrit, Hansen Laura A., A positive feedback loop between HER2 and ADAM12 in human head and neck cancer cells increases migration and invasion
  31:23, p. 2888 - 2898 2012
• Carcinogenesis
  Yanagida J., Hammiller B., Al-Matouq J., Behrens M., Trempus C. S., Repertinger Susan K., Hansen Laura A., Accelerated elimination of ultraviolet-induced DNA damage through apoptosis in CDC25A deficient skin
  33:9, p. 1754 - 1761 2012
• The FASEB journal
  Trotter Caitlyn, Hansen Laura, Conway Marianne, Maklad Adel, Evidence for critical period in development of cutaneous innervation: A study in nude mice
  25:S1, p. lb29 - lb29 2011
• Anatomical Record
  Maklad Adel, Conway Marianne, Hodges Cole, Hansen Laura A., Development of innervation to maxillary whiskers in mice
  293:9, p. 1553 - 1567 2010
• Molecular Carcinogenesis
  Virador Victoria M., Strain Kathryn, Anders Joanna, Cataisson Christophe, Hansen Laura A., Yuspa Stuart H., Flores-Obando Rafael E., Berry Adam, Patel Rinal, Zakhari Julia, Lo Yu Chien, The human promyelocytic leukemia protein is a tumor suppressor for murine skin carcinogenesis
  48:7, p. 599 - 609 2009
• Molecular Carcinogenesis
  Virador Victoria M., Flores-Obando Rafael E., Berry Adam, Patel Rinal, Zakhari Julia, Lo Yu-Chien, Strain Kathryn, Hansen Laura A., Yuspa Stuart H., Anders Joanna, Cataisson Christophe, The Human Promyelocytic Leukemia Protein Is a Tumor Suppressor for Murine Skin Carcinogenesis
  48:7, p. 599 - 609 2009
• American Journal of Pathology
  Madson Justin G., Tennant Raymond W., Hansen Laura A., Bowles Andrew, Trempus Carol S., Lynch David T., Svoboda Jessica, Ophardt Rebecca, Yanagida Jodi, Putta Sumanth K., Erbb2 Suppresses DNA Damage-Induced Checkpoint Activation and UV-Induced Mouse Skin Tumorigenesis
  174:6, p. 2357 - 2366 2009
• Journal of Investigative Dermatology
  Maklad Adel, Nicolai Jodi R., Bichsel Kyle J., Evenson Jackie E., Lee Tang-Cheng, Threadgill David W., Hansen Laura A., The EGFR Is Required for Proper Innervation to the Skin
  129:3, p. 690 - 698 2009
• Cell and Tissue Research
  Beisel Kirk W., Hansen Laura A., Soukup Garrett A., Fritzsch Bernd, Regenerating cochlear hair cells: quo vadis stem cell
  333:3, p. 373 - 379 2008
• Toxicologic pathology
  Lynch Dave, Svoboda Jessica, Putta Sumanth, Hofland Hans E.J., Chern Wendy H., Hansen Laura A., Mouse skin models for carcinogenic hazard identification
  35:7, p. 853 - 864 2007
• Molecular Carcinogenesis
  Madson J. G., Hansen Laura A., Multiple mechanisms of Erbb2 action after ultraviolet irradiation of the skin
  46:8, p. 624 - 628 2007
• Pediatric Dermatology
  Hornung R. L., Hansen Laura A., Sharp L. K., Poorsattar S. P., Lipsky M. S., Skin cancer prevention in the primary care setting: assessment using a standardized patient
  24:2, p. 108 - 112 2007
• Toxicologic Pathology
  Lynch Dave, Svoboda Jessica, Putta Sumanth, Hofland Hans E. J., Chern Wendy H., Hansen Laura A., Mouse skin models for carcinogenic hazard identification: utilities and challenges
  35:7, p. 853 - 864 2007
• Journal of Biomedicine and Biotechnology
  El-Abaseri Taghrid B., Hansen Laura A., EGFR activation and ultraviolet light-induced skin carcinogenesis, p. 97939 2007
• BioEssays
  Fritzsch Bernd, Beisel Kirk W., Hansen Laura A., The molecular basis of neurosensory cell formation in ear development: a blueprint for hair cell and sensory neuron regeneration?
  28:12, p. 1181 - 1193 2006
• American Journal of Pathology
  Madson Justin G., Lynch David T., Tinkum Kelsy L., Putta Sumanth K., Hansen Laura A., Erbb2 regulates inflammation and proliferation in the skin after ultraviolet irradiation
  169:4, p. 1402 - 1414 2006
• Brain Research
  Morris Jacqueline K., Lee Kuo Fen, Macklin Wendy B., Fritzsch Bernd, Maklad Adel, Hansen Laura A., Feng Feng, Sorensen Christian, A disorganized innervation of the inner ear persists in the absence of ErbB2
  1091:1, p. 186 - 199 2006
• Carcinogenesis
  El-Abaseri Taghrid B., Putta Sumanth K., Hansen Laura A., Ultraviolet irradiation induces keratinocyte proliferation and epidermal hyperplasia through the activation of the epidermal growth factor receptor
  27:2, p. 225 - 231 2006
• Lung cancer (Amsterdam, Netherlands)
  Jensen R., Spang-Thomsen M., Hansen L., P-057 Expression of the cyclin-dependent kinase inhibitor p21 is linkedto regulation of RAD51 in response to etoposide treatment of small cell lung cancer cells
  49, p. S129 - S129 2005
• Cancer Research
  El-Abaseri Taghrid B., Tennant R. W., Hansen Laura A., Fuhrman Jill, Trempus C., Shendrik I., Chemoprevention of UV light-induced skin tumorigenesis by inhibition of the epidermal growth factor receptor.
  65:9, p. 3958 - 3965 2005
• Toxicologic pathology
  Fuhrman Jill, Shafer Laura, Repertinger Susan, Chan Tom, Hansen Laura A., Mechanisms of SEPA 0009-induced tumorigenesis in v-rasHa transgenic Tg.AC mice.
  33:6, p. 623 - 630 2005
• Journal of Investigative Dermatology
  Repertinger Susan K., Campagnaro E., Fuhrman Jill, El-Abaseri Taghrid B., Yuspa S. H., Hansen Laura A., EGFR enhances early healing after cutaneous incisional wounding
  123:5, p. 982 - 989 2004
• Pharmacotherapy
  Snella Kathleen A., Trewyn Rence R., Hansen Laura A., Bradberry J. Chris, Pharmacist Compensation for Cognitive Services: Focus on the Physician Office and Community Pharmacy
  24:3, p. 372 - 388 2004
• Journal of Biological Chemistry
  Wei Sung Jen, Trempus Carol S., Ali Robin C., Hansen Laura A., Tennant Raymond W., 12-O-Tetradecanoylphorbol-13-acetate and UV Radiation-induced Nucleoside Diphosphate Protein Kinase B Mediates Neoplastic Transformation of Epidermal Cells
  279:7, p. 5993 - 6004 2004
• Cell and Tissue Research
  Maklad Adel, Fritzsch Bernd, Hansen Laura A., Innervation of the maxillary vibrissae in mice as revealed by anterograde and retrograde tract tracing
  315:2, p. 167 - 180 2004
• Cancer Research
  Hansen Laura A., Brown D., Virador V., Tanaka T., Andreola F., Strain K., Dancheck B., Riley R., Arbeit J. M., De Luca L. M., Kogan S., Yuspa S. H., A PMLRARA transgene results in a retinoid-deficient phenotype associated with enhanced susceptibility to skin tumorigenesis
  63:17, p. 5257 - 5265 2003
• Cancer Research
  Hansen Laura A., Brown Diane, Virador Victoria, Strain Kathryn, Dancheck Barbara, Riley Rebeccah, Arbeit Jeffrey M., De Luca Luigi M., Kogan Scott, Yuspa Stuart H., Andreola Fausto, Tanaka Takemi, A PMLRARA transgene results in a retinoid-deficient phenotype associated with enhanced susceptibility to skin tumorigenesis
  63:17, p. 5257 - 5265 2003
• Oncogene
  Seker Hasan, Rubbi Carlos, Linke Steven P., Bowman Elise D., Garfield Susan, Hansen Laura, Borden Katherine L.B., Milner Jo, Harris Curtis C., UV-C-induced DNA damage leads to p53-dependent nuclear trafficking of PML
  22:11, p. 1620 - 1628 2003
• Molecules and cells
  Chi Y, Frantz J, OH B, Hansen L, Shoelson S, , DIABETES MUTATIONS DELINEATE AN ATYPICAL POU DOMAIN IN HNF1A
  10 2002
• Cancer research
  Hansen L A, Woodson R L, Holbus S, Lo Y C, Yuspa S H, Strain K, The epidermal growth factor receptor is required to maintain the proliferative population in the basal compartment of epidermal tumors
  60:13, p. 3328 - 3332 2000
• Cancer Research
  Hansen Laura A., Woodson Roderick L., Holbus Sherry, Strain Kathryn, Lo You Chein, Yuspa Stuart H., The epidermal growth factor receptor is required to maintain the proliferative population in the basal compartment of epidermal tumors
  60:13, p. 3328 - 3332 2000
• Carcinogenesis
  Hansen Laura A., Sigman Caroline C., Andreola Fausto, Ross Sharon A., Kelloff Gary J., De Luca Luigi M., Retinoids in chemoprevention and differentiation therapy
  21:7, p. 1271 - 1279 2000
• Medicina
  Yuspa Stuart H., Hansen Laura, Li Luowei, Joseloff Elizabeth, Weinberg Wendy, Fernandez-Salas Ester, Interacting signaling pathways in the pathogenesis of squamous cell carcinoma
  60:5 II, p. 689 - 692 2000
• Carcinogenesis
  Hansen Laura A., Malarkey David E., Wilkinson J. Erby, Rosenberg Michael, Woychik Richard E., Tennant Raymond W., Effect of the viable-yellow (A(vy)) agouti allele on skin tumorigenesis and humoral hypercalcemia in v-Ha-ras transgenic TG.AC mice
  19:10, p. 1837 - 1845 1998
• Experimental Cell Research
  Saitoh Atsushi, Hansen Laura A., Vogel Jonathan C., Udey Mark C., Characterization of Wnt gene expression in murine skin
  243:1, p. 150 - 160 1998
• Genes and Development
  Robles Ana I., Rodriguez-Puebla Marcelo L., Glick Adam B., Trempus Carol, Hansen Laura, Sicinski Piotr, Tennant Raymond W., Weinberg Robert A., Yuspa Stuart H., Conti Claudio J., Reduced skin tumor development in cyclin D1-deficient mice highlights the oncogenic ras pathway in vivo
  12:16, p. 2469 - 2474 1998
• Cancer Research
  Tennenbaum Tamar, Hansen Laura, Lowry David, Darwiche Nadine, Morgan David L., Gartsbein Marina, De Luca Luigi M., Hennings Henry, Yuspa Stuart H., Topical retinoic acid reduces skin papilloma formation but resistant papillomas are at high risk for malignant conversion
  58:7, p. 1435 - 1443 1998
• Toxicologic pathology
  Humble Michael C., Szczesniak Carl J., Luetteke Noreen C., Spalding Judson W., Cannon Ronald E., Hansen Laura A., Lee David C., Tennant Raymond W., TGFα is dispensable for skin tumorigenesis in Tg.AC mice
  26:4, p. 562 - 569 1998
• American Journal of Pathology
  Hansen Laura A., Alexander Natalie, Hogan Margaret E., Sundberg John P., Dlugosz Andrzej, Threadgill David W., Magnuson Terry, Yuspa Stuart H., Genetically null mice reveal a central role for epidermal growth factor receptor in the differentiation of the hair follicle and normal hair development
  150:6, p. 1959 - 1975 1997
• Carcinogenesis
  Hansen Laura A., Trempus Carol S., Mahler Joel F., Tennant Raymond W., Association of tumor development with increased cellular proliferation and transgene overexpression, but not c-Ha-ras mutations, in v-Ha-ras transgenic Tg.AC mice
  17:9, p. 1825 - 1833 1996
• Science (American Association for the Advancement of Science)
  Threadgill David W, Dlugosz Andrzej A, Hansen Laura A, Tennenbaum Tamar, Lichti Urike, Yee Della, LaMantia Christian, Mourton Tracy, Herrup Karl, Harris Raymond C, Magnuson Terry, Barnard John A, Yuspa Stuart H, Coffey Robert J, Targeted distribution of mouse EGF receptor: effect of genetic background on mutant phenotype.(epidermal growth factor receptor)
  269:5221, p. 230 1995
• Archives of Oral Biology
  Wright J. T., Hansen L., Mahler J., Szczesniak C., Spalding J. W., Odontogenic tumours in the v-Ha-ras (TG · AC) transgenic mouse
  40:7, p. 631 - 638 1995
• Progress in clinical and biological research
  Hansen L. A., Spalding J. W., French J. E., Tennant R. W., A transgenic mouse model (TG.AC) for skin carcinogenesis
  391, p. 223 - 235 1995
• Science
  Threadgill David W., Coffey Robert J., Magnuson Terry, Yee Della, LaMantia Christian, Mourton Tracy, Herrup Karl, Harris Raymond C., Barnard John A., Yuspa Stuart H., Dlugosz Andrzej A., Hansen Laura A., Tennenbaum Tamar, Lichti Ulrike, Targeted disruption of mouse EGF receptor
  269:5221, p. 230 - 234 1995
• Molecular Carcinogenesis
  French John E., Libbus Bisharah L., Hansen Laura, Spalding Judson, Tice Raymond R., Mahler Joel, Tennant Raymond W., Cytogenetic analysis of malignant skin tumors induced in chemically treated TG.AC transgenic mice
  11:4, p. 215 - 226 1994
• Proceedings of the National Academy of Sciences - PNAS
  Hansen Laura, Tennant Raymond, Follicular origin of epidermal papillomas in v-Ha-ras transgenic TC.AC mouse skin
  91:16, p. 7822 1994
• Mutagenesis
  Tennant Raymond W., Hansen Laura, Spalding Judson, Gene manipulation and genetic toxicology
  9:3, p. 171 - 174 1994
• Molecular Carcinogenesis
  Hansen Laura A., Tennant Raymond, Focal transgene expression associated with papilloma development in v‐Ha‐ras–transgenic TG.AC mice
  9:3, p. 143 - 154 1994
• Cancer genetics and cytogenetics
  Libbus Bisharah L., French John E., Spalding Judson, Hansen Laura, Tice Raymond R., Tennant Raymond W., Highly repetitive chromosome changes associated with skin tumor development in transgenic mice treated with TPA
  66:2, p. 152 - 152 1993
• Cancer Research
  Hansen Laura A., Monteiro-Riviere Nancy A., Smart Robert C., Differential Down-Regulation of Epidermal Protein Kinase C by 12–O-Tetradecanoylphorbol-13-acetate and Diacylglycerol
  50:18, p. 5740 - 5745 1990
• Breast cancer research and treatment
  SPANG-THOMSEN M, Rygaard K, Hansen L, Halvorsen A.-C, Vindeløv L. L, Brunner N, Growth kinetics of four human breast carcinomas grown in nude mice
  14:2, p. 235 - 243 1989
• Cancer Research
  Smart Robert C., Conney Allan H., Mills Kevin J., Hansen Laura A., Synthetic Lipid Second Messenger sn-1,2-Didecanoylglycerol
  49:16, p. 4455 - 4458 1989
• Water, Air, and Soil Pollution
  Hansen Laura A., A method for chemical fractionation of chloride from complex effluents
  42:3-4, p. 259 - 265 1988

Presentations

• Society for Investigative Dermatology Annual Meeting 2020
• MSBRF poster presentation, Flower isoforms regulate keratinocyte differentiation during cutaneous squamous cell carcinoma development. Justin Rudd, Kelsey Novak, Matti Holmes, Kelsey Hulen, Laura Hansen 2020
• EFFECTS OF ES1P3 AND ZF47-88 ON CELL VIABILITY OF SCC12.B2 AND SCC13 CELLS Ryan O'Gara, Thomas R. Holmes, Kelsey Hulen, Sándor Lovas, Laura A. Hansen Midwest Student Biomedical Research Forum, 2020 2020
• 1. Two-photon imaging of NADH in SKH1 mice reveals changes in keratinocyte metabolism with chronic UVA exposure. Dominick Myers, Katie D. Sotelo, Dan L. Che, Marifel F. Gabriel, Ben G. Huerter, Kelsey A. Jackson, Molly Myers, Duyen Nguyen, Brooke L. Yang, Laura A. Hansen, Michael G. Nichols, 83rd Annual Meeting of the Biophysical Society, Baltimore Maryland, March 2019 2019
• Sarah C. Gwazdacz, Sarah L. Schilchte, Matti Holmes, Natasha Sioda, Matthew C. Zimmerman, Gary Madsen, and Laura A. Hansen. The delivery and use of Pro-NPTM in the reduction of UV-induced oxygen radicals in skin. Midwest Student Biomedical Research Forum, March 2019. 2019
• Natasha Sioda, Tommy Holmes, Sarah Gwazdacz, Matti Homes, and Laura A. Hansen. Targeting 14-3-3 decreases anti-apoptotic signaling in squamous cell carcinoma in vivo. Midwest Student Biomedical Research Forum, March 2019. 2019
• Megan Machek, Matti Holmes, Caleb Freeman, Zhao-Yi Wang, Laura A. Hansen. Treatment of squamous cell carcinoma using ER-a36 targeted drug icaritin. Midwest Student Biomedical Research Forum, March 2019. 2019
• Sandor Lovas, Thomas Holmes, Nicholas Y. Palermo, and Laura A. Hansen. Developing pepetide analogs for skin cancer treatment. International Peptide Conference, 2019. 2019
• Invited Speaker, Title: Targeting CDC25A and 14-3-3e interactions in nonmelanoma skin cancer, International Investigative Skin Carcinogenesis Conference, Austin TX, October, 2018. 2018
• Targeting of estrogen receptor-α36 suppresses growth of cutaneous squamous cell carcinoma, Caleb Freeman, Matti Holmes, Zhao-Yi Wang, and Laura A. Hansen International Investigational Skin Carcinogenesis Conference, Orlando, Florida 2018
• Invited Speaker, Title: CDC25 and 14-3-3 in UV-induced skin cancer progression, American Society for Photobiology annual meeting 2018
• Targeting CDC25A suppression of apoptosis in cutaneous squamous cell carcinoma depends on 14-3-3e, Thomas R. Holmes and Laura A. Hansen, American Association for Cancer Research annual meeting, Chicago, IL 2018
• Flower Proteins and Cell Competition in Skin Cancer Kimberly M. Fazio, Nicholas Tran, Matti Holmes, Ekaterina Halivelakis, Celena Derderian, Justin G. Madson, Rajan Gogna, Laura A. Hansen, MSBRF 2018
• ESTROGEN RECEPTOR-a36 TARGETING BY ICARITIN RESTRICTS IN VIVO GROWTH OF SQUAMOUS CELL CARCINOMA IN XENOGRAFT BY INCREASING DIFFERENTIATION, DECREASING PROLIFERATION, AND REDUCING THE CANCER STEM CELL POPULATION, S. Caleb Freeman, Matti Holmes, Nicholas Tran, Kimberly Fazio, Zhao-Yi Wang2, Laura A. Hansen, MSBRF 2018
• TARGETING OF ESTROGEN RECEPTOR-α36 DECREASES SKIN CANCER STEM CELL NUMBERS AND SUPPRESSES SKIN CANCER GROWTH, Matti Holmes1, Caleb Freeman, Dan Pham, Tommy R. Holmes, Tammy Wang, Zhao-Yi Wang, Laura A. Hansen, MSBRF 2018
• Presentation of research for LB595 site visit 2017
• Invited Speaker, Title: Novel Targets for Skin Carcinogenesis, LB595 Cancer and Smoking-related Diseases Program 2017
• Invited Speaker, Title: Estrogen Receptor alpha 36 in skin cancer progression 2017
• Invited speaker, Title: Relocalized CDC25A suppresses cell death in cutaneous squamous cell carcinoma, The 12th International Skin Carcinogenesis Conference. 2017
• Invited Speaker, Title: Mechanisms of skin cancer development and progression, Department of Pharmacology, CUSOM 2016
• Seminar, Role of CDC25C phosphatase in non-melanoma skin cancer, LB595 2015
• Cassidy Plunkett, Brianna Hammiller, Kyle Bichsel, Jessica Gaulter, and Laura A. Hansen Epidermal growth factor receptor regulation of Stathmin 1 in mouse skin cancer, Creighton University Honors Day 2015
• Timothy Malouff, Kyle J. Bichsel, Yanhua Li, Brianna Hammiller, Carol Trempus, Laura A. Hansen EGFR AND STATHMIN1 IN PROGRESSION THROUGH THE HAIR CYCLE Midwest Student Biomedical Research Forum, 2015 *Third place poster presentation. 2015
• Lauren Nicola; Nicholas Tran; Jenan Al-Matouq; Brianna Hammiller; and Laura A. Hansen CYTOPLASMIC LOCALIZATION OF 14-3-3 IS ASSOCIATED WITH SUPPRESSION OF CELL DEATH IN CUTANEOUS SQUAMOUS CELL CARCINOMA Midwest Student Biomedical Research Forum 2015
• Invited Speaker, Title: HER2-regulated signaling in squamous cell carcinoma: 14-3-3 and CDC25, CU Department of Biomedical Sciences, 2014
• Invited Speaker, Title: HER2-regulated signaling in squamous cell carcinoma: ADAM12 and CDC25 phosphatases, Kansas State University 2014
• Al-Matouq, J.A., Ho, K.A., and Hansen, L.A. Increased cytoplasmic CDC25A phosphatases in cutaneous cquamous cell carcinoma leads to 14-3-3epsilon relocalization and suppression of apoptosis. Presentation at the American Association for Cancer Research Meeting, May 2014 2014
• Hansen, L.A. Novel biomarkers and therapeutic targets for nonmelanoma skin cancer. Oral presentation for LB595, April 2014 2014
• Al-Matouq, J.A., Ho, K.A., and Hansen, L.A. Increased cytoplasmic CDC25A phosphatases in cutaneous cquamous cell carcinoma leads to 14-3-3epsilon relocalization and suppression of apoptosis. Poster presentation at the Midwest Biomedical Student Research Forum, February, 2014 2014
• Platform presentation at the Society of Toxicology annual meeting in Baltimore MD 2009
• Invited speaker at Pennsylvania State University, College Station, PA 2008
• Invited seminar at UNL, Epidermal growth factor receptor: surprises from the skin 2008
• Invited speaker, VA, Omaha, NE 2008
• Erbb2 and ultraviolet irradiation in skin carcinogenesis, University of Nebraska, Lincoln, NE 2006
• Inhibition of erbB2 suppresses UV-induced skin tumorigenesis through a mechanism independent of EGFR, American Association for Cancer Research 2006
• The role of Erbb2 in the response of the skin to UV, Nebraska Center for Cellular Signaling 2006
• Seminar title: The role of erbB2 in UV-induced skin carcinogenesis. 2005
• Seminar title: EGFR in cutaneous innervation 2004
• EGFR in peripheral nervous system innervation 2004
• The epidermal growth factor receptor in cancer biology 2003
• Invited speaker, Growth factor receptors, sunlight, and skin cancer, National Institute for Environmental Health Sciences, Research Triangle Park, NC 2003
• Invited speaker at the Great Plains States Society for Molecular Biology and Genetics annual meeting 2003
• Invited speaker, 4th Annual Steve Schiff Center for Skin Cancer Research Symposium, Title: The epidermal growth factor receptor regulates cell cycling and cell death during skin carcinogenesis 2002
• Invited speaker, VA hospital, Title: The epidermal growth factor receptor regulates cell death and division during skin carcinogenesis 2001
• Invited speaker, 3rd Midwest Regional AAAS Meeting, Title: Regulation of cell growth and death by the epidermal growth factor receptor during skin carcinogenesis 2001
• Invited speaker, Department of Pharmacology Seminar Series, UNMC, Title: Regulation of cutaneous cell division and cell death by the epidermal growth factor receptor 2001
• Panel discussion member, National Institute for Environmental Health Sciences Science Forum Topic: Searching for Faculty Positions, A Discussion by TIP Grantees 2001
• A PMLRARalpha transgene results in a retinoid-deficient phenotype associated with enhanced susceptibility to skin tumorigenesis, poster presentation at the American Association for Cancer Research annual meeting 2001
• UNMC Department of Cell Biology, seminar, Title: Epidermal growth factor receptor mediated maintenance of cell proliferation in skin tumorigenesis. 2001
• 3/5/2001 UNMC Department of Biochemistry, seminar, Regulation of cell division and differentiation by the epidermal growth factor receptor in the skin. 2001

Awards

• Dr. Robert Heaney Graduate Research Mentor Award
  Creighton University
• 1st place Graduate Student Platform Presentation by student Justin Rudd
  1st place Graduate Student Platform Presentation by student Justin Rudd in Basic Sciences during University Research Week
• University Research Award
  Creighton University
• First Place Prize for Graduate Student Poster
  Awarded to my advisee Matti Holmes for her research performed in my lab
  Creighton University Research Day
• Third place prive for poster presentation by medical student and mentee Timothy Malouff at the Midwest Biomedical Student Research Forum
  Third place prive for poster presentation by medical student and mentee Timothy Malouff at the Midwest Biomedical Student Research Forum
• Third place poster awarded to my Ph.D. student Justin Madson at the Midwest Biomedical Student Research Forum
  Third place poster awarded to my Ph.D. student Justin Madson at the Midwest Biomedical Student Research Forum
• Society of Investigative Dermatology Eugene M. Farber Endowment Award
  Society of Investigative Dermatology Eugene M. Farber Endowment Award

Consulting

• Protransit Nanotherapy, LLC External Advisory Board
  Board Member
  Protransit Nanotherapy
  2015 - 2015