Sandor Lovas, PhD

Department

Biomedical Sciences

Position

Professor

Books

• Lovas, S.; Watts, C.R. Misfolding and Oligomerization of Amyloid b(1-40). In Proceedings of the 24th American Peptide Symposium, Srivastava, V.; Yudin, A.; Lebl, M.. (Eds.) American Peptide Society, 2015, 217-219. doi:10.17952/24APS.2015.217 2015

Articles

• Carcinogenesis
  Holmes, T.R.; Al-Matouq, J.; Holmes, M.; Sioda, N.; Rudd, J.; Bloom, C.; Nicola, L.; Palermo, N.Y.; Madson, J.G.; Lovas, S. and Hansen, L.A. Targeting 14-3-3ε activates apoptotic signaling to prevent cutaneous squamous cell carcinoma. doi:10.1093/carcin/bgaa091, PMID: 32816038
  42(2), p. 232-242 2021
• PLoS Pathogens
  Boyle, W.K.; Crystal L. Richards, C.L.; Dulebohn, D.P.; Zalud, A.K.; Shaw, J.A.; Lovas, S.; Gherardini, F.C.; Bourret, T.J. DksA-dependent regulation of RpoS contributes to Borrelia burgdorferi tick-borne transmission and mammalian infectivity. PloS Pathogens, 2021, 17(2): e1009072, doi:10.1371/journal.ppat.1009072. 2021
• bioRxiv
  Boyle,W.K.; Crystal L. Richards, C.L.; Dulebohn, D.P.; Zalud, A.K.; Shaw,J.A.; Lovas, S.; Gherardini, F.C.; Bourret, T.J. DksA-dependent regulation of RpoS contributes to Borrelia burgdorferi tick-borne transmission and mammalian infectivity. bioRxiv 2020, doi: https://doi.org/10.1101/2020.11.04.367946 2020
• Oncotarget
  Holmes, T.R.; Al-Matouq, J.; Holmes, M.; Nicola, L.; Lovas, S. and Hansen, L.A. Targeting 14-3-3 ε- CDC25A interactions to trigger apoptotic death in skin cancer. Oncotarget 2020, 11, 3267-3278, doi:10.18632/oncotarget.27700
  11, p. 3267-3278 2020
• Int. J. Mol. Sci.
  Voit-Ostricki, L.; Lovas, S. and Watts, C.R. Conformation and Domain Movement Analysis of Human Matrix Metalloproteinase-2: role of associated Zn2+ and Ca2+ cations.
  20(17), p. 4194; https://doi.org/10.3390/ijms20174194 2019
• Int. J. Mol. Sci.
  Gregory, A.J.; Voit-Ostricki, L.; Lovas, S. and Watts, C.R. Effects of Selective Substitutions of Cysteine Residues on the Conformational Properties of Chlorotoxin Explored by Molecular Dynamics Simulations.
  20(6), p. 1261; doi:10.3390/ijms20061261 2019
• Proceedings of the 35th European Peptide Symposium
  Voit-Ostricki, L.;  Lovas, S.;  Watts, C. Conformation and domain movement analysis of Human Matrix Metalloprotease-2: The role of associated Zn2+ and Ca2+ ions
  https://doi.org/10.17952/35EPS.2018.202, p. 202-203 2018
• Proteins: Structure function and Bioinformatics
  Watts, C.R.; Gregory, A.J.; Frisbie, C.P. and Lovas, S. Effects of Force Fields on the Conformational and Dynamic Properties of Amyloid β(1-40) Dimer Explored by Replica Exchange Molecular Dynamics Simulations.
  86(3), p. 279-300, doi: 10.1002/prot.25439 2017
• bioRxiv
  Charles R. Watts, Andrew Gregory, Cole Frisbie, Sándor Lovas. Effects of Force Fields on the Conformational and Dynamic Properties of Amyloid β(1-40) Dimer Explored by Replica Exchange Molecular Dynamics Simulations
  210286; doi: 10.1101/210286 2017
• Proteins: Structure, Function and Genetics
  Charles R. Watts, Andrew J. Gregory, Cole P. Frisbie, and Sándor Lovas.  Structural Properties of Amyloid b(1-40) Dimer Explored by Replica Exchange Molecular Dynamics Simulations. doi:10.1002/prot.25270, PMID: 28241387
  85(6), p. 1024-1044, doi:10.1002/prot.25270, 2017
• Protein and Peptide Letters
  Knappe, D.; Goldbach, T.; Hatfield, M.P.D.; Palermo, N.Y.; Weinert, S.; Sträter, N.; Hoffmann, R. and Lovas, S. Proline-rich Antimicrobial Peptides Optimized for Binding to Escherichia coli Chaperone DnaK. doi: 10.2174/0929866523666160719124712, PMID:274499.
  23, p. 1061-1071 2016
• Journal of Biological Chemistry
  Lovas, S.; He, D.Z.Z.; Liu, H.; Tang, J.; Pecka, J.L.; Hatfield M.P.ED. and Beisel, K.W. Anion-pi Interaction is the Mechanism for the Voltage-Dependent Response of Prestin, the Motor Protein of Cochlear Outer Hair Cells. doi: 10.1074/jbc.M115.649962, PMID: 26283790
  290, p. 24326-24339 2015
• Biopolymers: Peptide Sci.
  Otvos, L. Jr.; Kovalszky, I.; Olah, J.; Coroniti, R.; Knappe, D.; Nollmann, F.I.; Hoffmann, R.; Wade, J.D.; Lovas, S. and Surmacz, E. Optimization of Adiponectin-derived Peptides for Inhibition of Cancer Cell Growth and Signaling. doi:10.1002/bip.22627.
  104, p. 156-166 2015
• Frontiers in Chemistry
  Otvos, J. Jr.; Knappe, D.; Hoffmann, R.; Kovalszky, I.; Olah, J.; Hewitson, T.D.; Stawikowska, R.; Stawikowski, M.; Cudic, P.; Lin, F.; Wade, J.D.; Surmacz E. and Lovas, S. Development of Second Generation Peptides Modulating Cellular Adiponectin Receptor Responses.
  2:93, doi: 10.3389/fchem.2014.00093. PMID: 25368867, PMCID: PMC4201147. 2014
• Biopolymers: Peptide Sci.
  Otvos, L. Jr.; Kovalszky, I.; Olah, J.; Coroniti, R.; Knappe, D.; Nollmann, F.I.; Hoffmann, R.; Wade, J.D.; Lovas, S. and Surmacz, E. Optimization of Adiponectin-derived Peptides for Inhibition of Cancer Cell Growth and Signaling. doi: 10.1002/bip.22627.
  104, p. 156-166 2014
• He, D.Z.Z.; Lovas, S.; Ai, Y.; Li, Y.; Beisel, K.W. Prestin at Year 14: Progress and Prospect. Hearing Res. doi: 10.1016/j.heares.2013.12.002., PMID: 24361298.
  311, p. 25-35 2014
• J. Phys. Chem. B
  Lovas, S.; Zhang, Y.; Yu, J.; Lyubchenko, Y.L. Molecular Mechanism of Misfolding and Aggregation of Ab(13-23). doi: 10.1021/jp402938p. PMID: 23642026; PMCID: PMC3695694
  117, p. 6175-6186 2013
• Current Pharmaceutical Design
  Hatfield, M.P.D.; Lovas, S. Conformational Sampling Techniques. Curr. Pharm. Des. doi:10.2174/13816128113199990603, PMID: 23947647
  20, p. 3303-3313 2013
• Protein and Peptide Letters
  Hatfield, M.P.D.; Lovas, S. Role of Hsp70 in cancer growth and survival.
  19, p. 616-624. doi:10.2174/092986612800493968 2012
• J Pept Sci
  Palermo, N.Y.; Thomas, P.; Murphy, R.F. and Lovas, S. Hexapeptide Fragment of Carcinoembryonic Antigen which Acts as an Agonist of Heterogeneous Ribonucleoprotein M.
  18, p. 252-260, doi: 10.1002/psc.2393 2012
• J. Cell Sci.
  Tan, X.; Pecka, J.L.; Tang, J.; Lovas, S.; Beisel, K.W.; He, D.Z.Z. A motif of eleven amino acids is a structural adaptation that facilitates motor capability of eutherian prestin.
  125, p. 1039-1047. doi: 10.1242/jcs.097337 2012
• BMC Biotechnology
  Otvos, L., Jr.; Haspinger, E.; La Russa, F.; Maspero, Maspero, F.; Graziano, P.; M.; Kovalszky, I.; Lovas, S.; Nama, K.; Hoffmann, R.; Knappe, D.; Cassone, M.; Wade, J. and Surmacz, E. Design and Development of a Peptide-based Adiponectin Receptor Agonist for Cancer Treatment.
  11, p. 90. doi:10.1186/1472-6750-11-90 2011
• Biochemistry
  Kim, B-H.; Palermo, N.Y.; Lovas, S.; Zaikova, Z.; Keana, J.F.W. and Lyubchenko, Y.L. Single molecule AFM force spectroscopy study of Aβ-40 interactions.
  50, p. 5154–5162. doi:10.1021/bi200147a 2011
• J Phys Chem B
  Hatfield, M.P.D.; Murphy, R.F.; Lovas, S. The CLN025 Decapeptide Retains a b-Hairpin Conformation in Urea and Guanidium Chloride.
  115, p. 4971-4981. doi: 10.1021/jp111076j 2011
• Biopolymers
  Copps, J.; Murphy, R.F.; Lovas, S. Avian Pancreatic Polypeptide Fragments Refold to Native aPP Conformation When Combined in Solution: A CD and VCD Study.
  83, p. 32-38 2006
• Journal of Molecular Structure (THEOCHEM)
  Owen, M.C.; Komáromi, I.; Murphy, R.F.; Lovas, S. The conformational preference of Ca-centered radicals in proteins.
  759, p. 117-124. 2006
• Not Applicable
  Lovas, S.; Marai, C.N.J.; Borics, A.; Murphy, R.F. The influence of radical formation on the conformation of the amyloid β peptide fragment (25-35). p. 744-745
  Bridges Between Disciplines, Proceedings of the Third International and Twenty-Eight European Peptide symposium. Flegel, M.; Fridkin,M.; Gilon, C. and Slaninova J. (Eds.) 2005
• J. Phys. Chem. A
  Mirasol, R.S.; Setiadi, D.H.; Tang, T-H; Chin, W.; Mons, M.; Dimicoli, I.; Dognon, J-P.; Viskolcz, B.; Lovas, S.; Penke, B.; Chass, G.A. and Csizmadia, I.G. Characterization of the Conformational Probability of N-Acetyl-Phenylalanyl-NH2 by RHF, DFT, and MP2 Computation and AIM Analyses, Confirmed by Jet-Cooled Infrared Data.
  109, p. 5289-5302 2005
• Peptides
  Ahmed, S.; Murphy, R.F.; Lovas S. Importance of N- and C-terminal Regions of Gastrin-Gly for Preferential Binding to High and Low Affinity Gastrin-Gly Receptors.
  26, p. 1207-1212 2005
• Peptides
  Herédi-Szabó, K.; Lubke, J.; Tóth, G.; Murphy, R.F.; Lovas, S. Importance of the central region of lamprey gonadotropin-releasing hormone III in the inhibition of breast cancer cell growth.
  26, p. 419-422 2005
• Peptides: Genomics, Proteomics & Therapeutics
  Herédi-Szabó, K.; Lubke, J.; Murphy, R.F.; Lovas, S. The role of residues 5-8 of lamprey gonadotropin-releasing hormone III in the inhibition of cancer cell growth. Chorev, M. and Sawyer, T.K. (Eds.), American Peptide Society, 2004, 628-629. 2004
• Not Applicable
  Borics, A.; Murphy, R.F.; Lovas, S.; Molecular Dynamic Investigation of the b-Turn Forming Nature of Tetra- and Hexapeptides. In Peptide Revolution, Genomics, Proteomics & Therapeutics, Proceedings of the Eighteenth American Peptide Society, Chorev, M. and Sawyer, T.K. (Eds.) 2004, 400-401., p. 400-401 2004
• Not Applicable
  Borics, A.; Ene, C.; Otvos Jr, L.; Murphy, R.F.; Lovas, S. The Effect of Trp on UV- and Vibrational Circular Dichroism of Helical Peptides. In Peptide Revolution, Genomics, Proteomics & Therapeutics, Proceedings of the Eighteenth American Peptide Society, Chorev, M. and Sawyer, T.K. (Eds.) 2004
• J. Phys. Chem. B
  Tóth, G.; Kövér, K.E.; Murphy, R.F.; Lovas, S. Aromatic-Backbone Interactions in alpha-helices.
  108, p. 9287-9296 2004
• J. Biomol. Struct. & Dyn
  Borics, A.; Murphy, R.F.; Lovas, S.; Molecular Dynamics Simulations of b-Turn Forming Tetra- and Hexapeptides.
  21, p. 761-770 2004
• FEBS Lett.
  Ahmed, S.; Budai, B.; Herédi-Szabó, K.; Farkas, J.; Tóth, G.; Murphy, R.F.; Lovas, S. High and low affinity receptors mediate growth effects of gastrin and N-carboxymethyl gastrin on DLD-1 human colonic carcinoma cells.
  556, p. 199-203 2004
• J.Mol.Struct. (THEOCHEM)
  Sahai, M.A.; Lovas, S.; Chass, G.A.; Penke, B.; Csizmadia, I.G. A modular numbering system of selected oligopeptides for molecular computations.
  666-667, p. 169-218 2003
• J.Mol.Struct. (THEOCHEM)
  Borics, A.; Chass, G.A.; Csizmadia, I.G.; Murphy, R.F. and Lovas, A. The Benefits of a Pre-computed Amino Acid Structure Database in Quantum Chemical Geometry Optimizations of b-turns of Peptides.
  666-667, p. 355-359 2003
• J.Mol.Struct. (THEOCHEM)
  Lau, S. K.; Chass, G.A.; Lovas, S.; Penke, B.; Csizmadia, I.G. An Exploratory ab initio Conformational Analysis of Selected Fragments of Nicotinamide Adenine Dinucleotide (NAD+). Part I: 5-deoxyribose nicotinamide N-glycoside.
  66-667 2003
• J. Phys. Chem. B
  Bhattacharjee, S.; Tóth, G.; Lovas, S. and Hirst, J.D. Influence of Tyrosine on the Electronic Circular Dichroism of Helical Peptides
  107, p. 8682-8688 2003
• Biopolymers: Biospectroscopy
  Borics, A.; Murphy, R.F.; Lovas, S. Fourier Transform Vibrational Circular Dichroism as a Decisive Tool for Conformational Studies of Peptides Containing Tyrosyl Residues.
  72, p. 21-24 2003
• Recent Res. Devel. Peptides
  Palyi, I.; Vincze, B.; Mezö, I.; Pató, J.; Kálnay, A.; Gaál, D.;Seprödi, J.; Hudecz, F.; Mezö, G.; Lovas, S.; Murphy, R.F. New GnRH analog conjugates of high selectivity against cancer.
  1, p. 35-48 2002
• Not Applicable
  Ahmed, S.I.; Budai, B.; Murphy, R.F. and Lovas, S. Promotion of growth of colonic cancer cells by N-carboxymethyl gastrin through a non-CCK2 receptor. In Peptides 2002, Benedetti, E. & Pedone, C. (Eds), Ediziono Ziino, Napoli, Italy, 2002, pp. 820-821. 2002
• J. Chem. Soc., Perkin Trans. 2
  Keglevich, Gy.; Körtvélyesi, T.; Forintos, H.; Lovas, S. Structure and stability of oxaphosphetes formed as intermediates in the reaction of tertiary phosphine oxides and acetylenic derivatives. , p. 1645-1646 2002
• European Phys. J. D.
  Chass, G.A.; Lovas, S.; Murphy, R.F.; Csizmadia, I.G. The Role of Enhanced Aromatic -Electron Donating Aptitude of the Tyrosyl Sidechain with Respect to that of Phenylalanyl in Intramolecular Interactions.
  20, p. 481-497 2002
• Int. J. Quant. Chem.
  Chass, G.A.; Sahai, M.A.; Law, J.M.S.; Lovas, S.; Farkas, Ö; Perczel, A.; Csizmadia, I.G. Toward a Computed Peptide Structure Database: The role of a Universal Atomic Numbering System of Amino Acids in Peptides and Internal Hierarchy of Database.
  90, p. 933-968. 2002
• Eur. J. Biochem.
  Kragol, G.; Hoffmann, R.; Chattergoon, M.A.; Lovas, S.; Cudic, M.; Bulet, P.; Condie, B.A.; Rosengren, K.J.; Montaner, L.J.; Otvos, L., Jr. Identification of crucial residues for the antibacterial activity of the proline-rich peptide, pyrrhocoricin.
  269, p. 4226-4237 2002
• Peptides
  Gembitsky, D.S.; Bozsó, Zs.; O'Flaharty, M.; Ötvös, F.; Murphy, R.F.; Lovas, S. A specific binding site for a fragment of the B-loop of epidermal growth factor and related peptides.
  23, p. 97-102 2002
• Journal of the American Chemical Society
  Tóth, G.; Murphy, R.F.; Lovas, S. Investigation of Aromatic-Backbone Amide Interactions in the Model Peptide Acetyl-Phe-Gly-Gly-N-methyl amide Using Molecular Dynamics Simulations and Protein Database Search
  123, p. 11782-11790 2001
• Peptides: The Wave of the Future
  Ahmed, S.I.; Wibowo, F.; Gembitsky, D.S.; Murphy, R.F.; Lovas, S. Role of the C-terminal and Central Region of Gastrin for Recognition by the Human CCK2 Receptor. In Peptides, Lebl, M and Houghten R.S. (Eds.), American Peptide Society, San Diego, p. 693-694 2001
• Peptides: The Wave of the Future
  Tóth, G.; Kövér, K.E.; Hirst, J.; Murphy, R.F.; Lovas S. a-Helix stabilizing aromatic-backbone interactions. In Peptides, Lebl, M and Houghten R.S. (Eds.), American Peptide Society, San Diego, p. 303-305 2001
• Peptides: The Wave of the Future
  Otvos, L. Jr.; Kragol, G.; Varadi, Gy.; Condie, B.A.; Lovas, S. The Proline-rich antibacterial peptide family inhibits chaperone-assisted protein folding. In Peptides, Lebl, M and Houghten R.S. (Eds.), American Peptide Society, San Diego, 2001, p. 873-875. 2001
• Peptides: The Wave of the Future
  Wibowo, F.; Ahmed, S.I.; Gembitsky, D.S.; Lovas, S.; Murphy, R.F. Human colon cancers recognize N-carboxymethyl gastrin by a non-CCK1, non-CCK2 receptor. n Peptides, Lebl, M and Houghten R.S. (Eds.), American Peptide Society, San Diego, , p. 905-906 2001
• Synthetic Communication
  Somlai, Cs.; Lovas, S.; Forgo, P.; Murphy, R.F.; Penke, B. Dehydration of Threonine Esters During Tosylation.
  31, p. 65-72 2001
• Protein. Eng.
  Tóth, G.; Murphy, R.F. Lovas, S. Stabilization of Local Structures by pi-CH and Aromatic-Backbone Amide Interactions Involving Prolyl and Aromatic Residues.
  14, p. 543-547 2001
• Journal of Peptide Research
  Ahmed, S.I.; Wibowo, F.; Gembitsky, D.S.; Bozsó, Zs.; Murphy, R.F.; Lovas, S. Importance of the C-terminal Phenylalanine of Gastrin for Binding to the Human CCK2 Receptor.
  58, p. 332-337 2001
• Journal of Molecular Structure (THEOCHEM)
  Kortvelyesi, T.; Kiss, G.; Murphy, R.F.; Penke, B. and Lovas, S. Effect of Ala Substitution and N- and C-terminal Modification and the Presence of Counter Ions on the Structure of Amyloid Peptide Fragment Ab(25-35).
  545, p. 215-223 2001
• Proteins: Structure, Function and Genetics
  Toth, G.; Watts, C.R.; Murphy, R.F.; Lovas, S. Significance of Aromatic-Backbone Amide Interactions in Protein Structure.
  43, p. 373-381 2001
• Not Applicable
  Toth, G.; Murphy, R.F.; Lovas, S. Prolyl-Aromatic and Aromatic-Prolyl Local interactions in Polypeptides. Peptides 2000, J. Martinez and J. Fehrentz (Eds.), Editions EDK, Paris, , p. 533-534 2001
• Not Applicable
  Toth, G.; Watts, C.R.; Murphy, R.F. Lovas, S. Characterization of the Conformations of Polypeptides Containing Aromatic(i)-Amide(i+1, i+2) Interactions. Peptides 2000, J. Martinez and J. Fehrentz (Eds.), Editions EDK, Paris, p. 535-536 2001
• Not Applicable
  Gembitsky, D.S.; Lovas, S.; Ahmed, S.; Ryder, C.; Kopin, A.; Murphy, R.F. Contribution of C-Terminal Structures of Gastrin to Receptor Recognition. Peptides 2000, J. Martinez and J. Fehrentz (Eds.), Editions EDK, Paris, p. 109-110 2001
• Not Applicable
  Lovas, S.; Kortvelyesi, T.; Kleinman, H. K.; Otvos,F.; Murphy R.F. Requirements in the Turn Structures of SIKVAV for Stimulation of Neurite Outgrowth. Peptides 2000, J. Martinez and J. Fehrentz (Eds.), Editions EDK, Paris, p. 431-432 2001
• Journal of Biomolecular Structure & Dynamics
  Watts, C.R.; Mezei, M.; Murphy, R.F. and Lovas, S. Conformational Space Comparison of GnRH and lGnRH-III using Molecular Dynamics, Cluster Analysis and Monte Carlo Thermodynamic Integration.
  18, p. 733-748 2001
• British Journal of Cancer
  Murphy, L.O.; Cluck, M.W.; Lovas, S.; Otvos, F.; Murphy, R.F.; Schally, A.V.; Permert, J.; Larsson, J.; Knezetic, J.A. and Adrian, T.E. Pancreatic cancel cells require an EGF receptor-mediated autocrine pathway for proliferatoin in serum-free conditions.
  84, p. 926-935 2001
• Drugs of the Future
  Palyi, I.; Vincze, B.; Mezo, I.; Pato, J.; Kalnay, A.; Gaal, D.;Seprodi, J.; Hudecz, F.; Mezo, G.; Lovas, S.; Murphy, R.F. GnRH analog conjugates with high anticancer selectivity.
  26, p. 51-59 2001
• Biochemistry
  Kragol, G.; Lovas, S.; Varadi, Gy.; Condie, B.A.; Hoffmann, R.; Otvos, Jr., L. The antibacterial peptide pyrrhocoricin inhibits the ATPase actions of DnaK and prevents chaperone-assisted protein folding.
  40, p. 3016 -3026 2001
• Journal of Molecular Structure (THEOCHEM)
  Watts, C.R.; Toth, G.; Murphy, R.F.; Lovas, S. Domain Movement in the Epidermal Growth Factor Family of Peptides.
  535, p. 171-182 2001
• Journal of Molecular Structure (THEOCHEM)
  Kortvelyesi, T.; Kukovecz, A.; Lovas , S.; Palinko, I. Intramolecular hydrogen bonding in a-phenylcinnamic acids and their heteroatom-containing derivatives studied by ab initio quantum chemical methods.
  535, p. 139-149 2001
• Biochemistry
  Otvos, L.; Insug, O.; Rogers, M.E.; Consolvo, P.J.; Condie, B.A.; Lovas, S.; Bulet, P.; Blaszczyk-Thurin, M. Interaction between heat schock proteins and antimicrobial peptides.
  39, p. 14150-14159 2000
• Cell Proliferation
  Kalnay, A.; Palyi, I.; Vincze, B.; Mihalik R, Mezo, I.; Pato, J.; Seprodi, J.; Lovas, S.; Murphy, R.F. Influence of antiproliferative activity of structural modification and conjugation of gonadotropin-releasing hormone (GnRH) analogues.
  33, p. 275-285 2000
• Not Applicable
  Gembitsky, D.S.; Murphy. R.F.; Lovas, S.; Modulation of NK-2 receptor associated G-protein signaling by alternation of the aromatic residue at position six in neurokinin A analogs.in Peptides for the New Millenium Fields, G.B.; Tam, J.P.; Barany, G. (Eds.) Kluwer Aademic Publishers Dordrecht/Boston/London, 2000., p. 592-593 2000
• Letters in Peptide Science
  Bozso, Zs.; Toth, G.; Murphy, R.F.; Lovas, S. Difficulties in coupling to conformationally constrained aromatic amino acids.
  7, p. 157-163 2000
• Proceedings of the National Academy of Sciences
  Palyi, I.; Vincze, B; Lovas, S.; Mezo, I.; Pato, J.; Kalnay, A.; Turi, G.; Gaal, D.; Mihalik, R.; Peter, I.; Teplan, I.; Murphy, R.F. Novel gonadotropin releasing hormone (GnRH) analog conjugates with strong selective antitumor activity.
  96, p. 2361-2366. 1999
• J. Peptide Res.
  Otvos, F.L.; Murphy, R.F.; Lovas, S. Coupling Difficulty Following Replacement of Tyr with HOTic During Synthesis of an Analog of an EGF B-Loop Fragment.
  53, p. 302-307 1999

Publications

• J Pept Sci
  Otvos, L.; Kovalszky, I.; Wade, J.D.; Knappe, D.; Hoffmann, R.; Lovas, S. Second Generation Adiponectin-Derived Peptides Against Cancer. J Pept. Sci.
  20, p. S228 2014
• Biopolymers: Peptide Sci.
  Copps, J.; Murphy. R.F.; Lovas, S. VCD Spectroscopic Analysis of the Truncated Exendin-4 Analog TC5B.
  80, p. 505 2005
• Biopolymers: Peptide Sci.
  Borics, A.; Murphy, R.F.; Lovas, S. Type II b-Turn Formation in Tetrapeptides Evidenced by Vibrational Circular Dichroism Spectroscopy.
  80, p. 505 2005
• Biopolymers: Peptide Sci.
  Owen, M.; Murphy, R.F.; Lovas, S. The Conformational Preference of C-a Centered Protein Radicals.
  80, p. 506 2005
• Biopolymers: Peptide Sci.
  Herédi-Szabó, K.; Murphy, R.F.; Lovas, S. Antiproliferative Effect of Lamprey Gonadotropin-Releasing Hormone III on Cancer Cells from Non-Reproductive Organs.
  80, p. 513 2005
• Regulatory Peptides
  Ahmed, S.; Copps, J.; Babin, D.; Murphy R.F.; Lovas, S. The conformation required for the binding of gastrin to the human CCK2 receptor.
  122, p. 33 2004
• Regulatory Peptides
  Ahmed, S.; Lovas, S.; Murphy R.F. Gastrin-Gly and gastrin stimulate growth of colonic cancer cells, binding non-CCK1, non-CCK2 receptors.
  122, p. 32 2004
• Biopolymers: Peptide Sci.
  Borics, A.; Murphy, R.F.; Lovas, S.; Molecular Dynamic Investigation of the Beta-Turn Forming Nature of Tetra- and Hexapeptides.
  71, p. 308 2003
• Biopolymers: Peptide Sci.
  Herédi-Szabó, K.; Lubke, J.; Murphy, R.F.; Lovas, S. The role of residues 5-8 of lamprey gonadotropin-releasing hormone III in the inhibition of cancer cell growth.
  71, p. 309 2003
• Biopolymers: Peptide Sci.
  Borics, A.; Ene, C.; Otvos Jr, L.; Murphy, R.F.; Lovas, S. The Effect of Trp on UV- and Vibrational Circular Dichroism of Helical Peptides.
  71, p. 333 2003
• J. Peptide Science
  Ahmed, S.I.; Budai, B.; Murphy, R.F. and Lovas, S. Promotion of growth of colonic cancer cells by N-carboxymethyl gastrin through a non-CCK2 receptor. 27th Europen Peptide Symposium
  S8, p. S206 2002
• 6th World Congress of Theoretically Oriented Chemist
  Chass, G.A.; Murphy, R.F.; Csizmadia, I.G; Lovas, S. An Ab Initio Conformational Study of the ---H2C,, Interaction Between Aromatic and Prolyl Residues. 6th World Congress of Theoretically Oriented Chemist. Lugano, Switzerland, Program and Abstracts, 2002, PC444. 2002
• 6th World Congress of Theoretically Oriented Chemist
  Chass, G.A.; Lovas, S.; Farkas, Ö; Perczel, A.; Csizmadia, I.G. Toward a Computed Peptide Structure Database. 6th World Congress of Theoretically Oriented Chemist. Lugano, Switzerland, Program and Abstracts, 2002, PB305. 2002
• Not Applicable
  Toth, G.; Kover, K.E.; Hirst, J.; Murphy, R.F.; Lovas S. Helix stabilizing aromatic-backbone interactions. 2nd International and 17th American Peptide Symposium, San Diego, USA. Program and Abstracts, 2001, L73. 2001
• Not Applicable
  Ahmed, S.I.; Wibowo, F.; Gembitsky, D.S.; Murphy, R.F.; Lovas, S. Role of the C-terminal and Central Region of Gastrin for Recognition by the Human CCK2 Receptor. 2nd International and 17th American Peptide Symposium, San Diego, USA. Program and Abstracts, 2001, P330. 2001
• Not Applicable
  Bozso, Zs.; Gembitsky, D.S.; O'Flaharty, M.; Otvos, F.; Murphy, R.F.; Lovas, S. The B-loop fragment of EGF has a binding site distinct from the EGF receptor. 2nd International and 17th American Peptide Symposium, San Diego, USA. Program and Abstracts, 2001, P522. 2001
• Not Applicable
  Wibowo, F.; Ahmed, S.I.; Gembitsky, D.S.; Lovas, S.; Murphy, R.F. Human colonic cancer cells recognize N-carboxymethyl gastrin by a non CCK1, non CCK2 receptor. 2nd International and 17th American Peptide Symposium, San Diego, USA. Program and Abstracts, 2001, P523. 2001
• Not Applicable
  Pato, J.; Vincze, B.; Palyi, I.; Kremmer, T.; Csuka, O.; Toth, G.; Gaal, D.; Seprodi, J.; Mezo, I.; Lovas, S.; Murphy, R.F. New biological properties of GnRH analogs cunjugated to a polyanionic carrier. 2nd International and 17th American Peptide Symposium, San Diego, USA. Program and Abstracts, 2001, P445. 2001
• Not Applicable
  Otvos, L. Jr.; Kragol, G.; Varadi, Gy.; Condie, B.A.; Lovas, S. The Proline-rich antibacterial peptide family inhibits chaperone-assisted protein folding. 2nd International and 17th American Peptide Symposium, San Diego, USA. Program and Abstracts, 2001, L55. 2001
• Not Applicable
  Lovas, S.; Kortvelyesi, T.; Kleinman, H.; Otvos,F.; Murphy R.F. The Structural Requirements in the Turn Structures of SIKVAV for Biological Activity. J. Pept. Sci., Supplement to Vol. 6, 26th European Peptide Symposium. 2000, S131. 2000
• Not Applicable
  Toth, G.; Watts, C.R. ; Murphy, R.F.; Lovas, S. Characterization of the Conformations of Polypeptides Containing Aromatic(i)-Amide(i+1, i+2) Interactions. J. Pept. Sci., Supplement to Vol. 6, 26th European Peptide Symposium . 2000, S147. 2000
• Not Applicable
  Toth, G.; Murphy, R.F.; Lovas, S. Prolyl-Aromatic and Aromatic-Prolyl Local interactions in Polypeptides. J. Pept. Sci., Supplement to Vol. 6, 26th European Peptide Symposium Program and Abstracts. 2000, S147. 2000
• Not Applicable
  Gembitsky, D.S.; Lovas, S.; Ahmed, S.; Ryder, C.; Kopin, A.; Murphy, R.F. Contribution of C-Terminal Structures of Gastrin to Receptor Recognition.J. Pept. Sci., Supplement to Vol. 6, 26th European Peptide Symposium. 2000, S72. 2000
• Not Applicable
  Four at the 16th American Peptide Symposium, 1999, Minneapolis, U.S.A. 1999
• Not Applicable
  One at the 5th World Congress of Theoretically Oriented Chemist, 1999, London, U.K. 1999
• Not Applicable
  One at the 16th American Peptide Symposium, M, Minneapolis, USA 1999 1999
• Not Applicable
  One at the 5th World Congress of Theoretically Oriented Chemists, 1999, London, U.K. 1999