Alessandra M. Campos-Staffico, PhD
Assistant Professor

Contact
School of Pharmacy and Health Professions
Faculty - Pharmacy, OT, PT
Pharmacy Faculty
Pharmacy Sciences Faculty
Pharmacy Sciences
HLSB - Hixson Lied Science Building
Alessandra M. Campos-Staffico, PhD
Assistant Professor
Research Focus
Cardiovascular Pharmacogenetics & Pharmacogenomics- Direct Oral Anticoagulants in non-valvular atrial fibrillation
- Survival benefits of heart failure medications
- Statin-induced myopathy
- Drug-induced QT prolongation
- Genome-wide association studies (GWAS)
- Polygenic predictive scores
- Assessment of risk prediction tools for cardiovascular diseases
- Identification of clinical and genetic predictors for cardiovascular diseases
- Primary and secondary drug prevention studies for cardiovascular diseases
Department
Pharmacy Sciences
Position
Assistant Professor
Books
- Cardiology - Anticoagulants, Antiplatelets, and Antihyperlipidemics
CAMPOS-STAFFICO AM, Clinical Pharmacokinetics and Pharmacodynamics, A Precision Medicine Approach 2023 - Abordagens Interdisciplinares em Saúde da Família 2023
CAMPOS-STAFFICO AM, Stephanus AD Pharmacotherapy in Elderly Patients
2, p. 232-57 2023 - Atualização em Hipertensão Arterial. 2nd ed. São Paulo: Atheneu, 2007,
Neves FAR, CAMPOS AM Renin-angiotensin System, p. 93-102 2007
Articles
- Research and Practice in Thrombosis and Haemostasis
CAMPOS-STAFFICO AM, Jacoby JP; Dorsch MP; Limdi NA; Barnes GD; Luzum JA Risk Scores for Major Bleeding from Direct Oral Anticoagulants: Comparing Predictive Performance in Patients with Atrial Fibrillation 2023 - Gene
Luzum JA, CAMPOS-STAFFICO AM; Li J; She R; Gui H; Peterson EL; Liu B; Sabbah HN; Williams LK; Lanfear DE Genome-Wide Association Study of Beta-Blocker Survival Benefit in Black and White Patients with Heart Failure with Reduced Ejection Fraction 2023 - Frontiers in Clinical Diabetes
Barreto J, CAMPOS-STAFFICO AM; Nadruz W; Quinaglia T; Sposito AC The Role of SGLT2i in Attenuating Residual Cardiovascular Risk Through Blood Pressurelowering: Mechanistic Insights and Perspectives 2023 - Clin J Am Soc Nephrol
Barreto J, Borges C; Rodrigues TB; Jesus DC; CAMPOS-STAFFICO AM; Nadruz W; Costa JL; Oliveira RB; Sposito AC Pharmacokinetic Properties of Dapagliflozin in Hemodialysis and Peritoneal Dialysis Patients 2023 - J Clin Densitom
Stephanus AD, Ramos SCL; Seguti VF; Netto OS; Moraes CF; Gomes LO; Carvalho LSF; CAMPOS-STAFFICO AM Subclinical Hypothyroidism is not Associated with Femoral Osteopenia and Osteoporosis in Individuals Aged 50 years or Older
2, p. 101362 2023 - Front Pharmacol
CAMPOS-STAFFICO AM, Dorsch MP; Barnes GD; Zhu H; Limdi NA; Luzum JA Eight PK-related Genetic Variants were not Associated with the Risk of Bleeding from Direct Oral Anticoagulants in Individuals with Non-Valvular Atrial Fibrillation
13, p. 1007113 2022 - Atherosclerosis
CAMPOS-STAFFICO AM, Cordwin D; Murthy VL; Dorsch MP; Luzum JA Comparative Performance of the Two Pooled Cohort Equations for Predicting Atherosclerotic Cardiovascular Disease
334, p. 23-29 2021 - Preventive Medicine
Campos-Staffico AM, Cordwin D; Ding Y; Lester CA; Brook RD; Luzum JA; Dorsch MP Fewer Patients Receive Recommendations for Pharmacotherapy in Primary Prevention Using the 2018 Atherosclerotic Cardiovascular Disease Risk Estimator
148:106555 2021 - Int J Gen Med
Nbrega OT, CAMPOS-STAFFICO AM; Oliveira EK; Munhoz DB; Moura FA; Carvalho LSF; Soares AASM; Gomes CM; Tonet-Furioso AC; Sposito AC Defective Allele of the Neuronal Nitric Oxide Synthase Gene Increases Insulin Resistance During Acute Phase of Myocardial Infarction
14, p. 3669-3676 2021 - Journal of Cardiovascular Electrophysiology
Lopez-Medina AI, Campos-Staffico AM; Luzum JA QT Prolongation with Hydroxychloroquine and Azithromycin for the Treatment of COVID-19: The Need for Pharmacogenetic Insights
31(10), p. 2793-2794 2020 - Atherosclerosis
Campos-Staffico AM, Freitas WM; Carvalho LSF; Coelho-Filho OR; Nadruz W Jr; Oliveira RB; Sposito AC Lower Bone Mass is Associated with Subclinical Atherosclerosis, Endothelial Dysfunction and Carotid Thickness in the Very Elderly
292, p. 70-74. 2020 - Sci Rep
Sposito AC, Carvalho LSF; Moura FA; CAMPOS-STAFFICO AM; Cintra RMR; Nadruz W; Almeida OR; Quinaglia E Silva JC Statin Short-term Inhibition of Insulin Sensitivity and Secretion During Acute Phase of ST-Elevation Myocardial Infarction
1, p. 16401 2019 - Am J Pharmaceutical Education
dos Reis TM, de Oliveira Baldoni A; CAMPOS AM; Girotto E; Guidoni CM; Obreli-Neto PR; Leira Pereira LR A Distance-Learning Course to Improve Drug-Dispensing Behaviors Among Brazilian Community Pharmacists
8, p. 6874 2019 - Nutr J
CAMPOS-STAFFICO AM, Costa APR; Carvalho LSF; Moura FA; Santos SN; Coelho-Filho OR; Nadruz W Jr; Quinaglia E Silva JC; Sposito AC Omega-3 Intake is Associated with Attenuated Inflammatory Response and Cardiac Remodeling After Myocardial Infarction
1, p. 29 2019 - Diabetes Care
de Carvalho LSF, CAMPOS AM; Sposito AC Response to Comment on de Carvalho et al. Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibitors and Incident Type 2 Diabetes: A Systematic Review and Meta-analysis With Over 96,000 Patient-Years
4, p. e70-e71 2018 - J Lipid Res
Zimetti F, Freitas WM; CAMPOS AM; Daher M; Adorni MP; Bernini F; Sposito AC; Zanotti I Cholesterol Efflux Capacity does not Associate with Coronary Calcium, Plaque Vulnerability, and Telomere Length in Healthy Octogenarians
4, p. 714-721 2018 - Diabetes Care
de Carvalho LSF, CAMPOS AM; Sposito AC Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibitors and Incident Type 2 Diabetes: A Systematic Review and Meta-analysis With Over 96,000 Patient-Years
2, p. 364-367 2018 - Atherosclerosis
CAMPOS AM, Moura FA; Santos SN; Freitas WM; Sposito AC Sarcopenia, but not Excess Weight or Increased Caloric Intake, is Associated with Coronary Subclinical Atherosclerosis in the Very Elderly, p. 138-144 2017 - BBA Clin
CAMPOS AM, Placido-Sposito A; Freitas WM; Moura FA; Guariento ME; Nadruz W Junior; Moriguchi EH; Sposito AC ST-Elevation Myocardial Infarction Risk in the Very Elderly, p. 108-12 2016 - Arq Bras Endocrinol Metab
Barra GB, Velasco LFR; Pessanha RP; CAMPOS AM; Moura FN; Dias SMG; Polikarpov I; Ribeiro RCJ; Simeoni LA; Neves FAR Molecular Mechanism of Thyroid Hormone Action
1, p. 25-39 2004
Publications
- Rev Soc Cardiol Estado de São Paulo
Stephanus AD, Santos A, Pereira A, Cappele A, Freitas WM, Fernandez M, Nogueira AC, CAMPOS-STAFFICO AM, Carvalho LSF Hypothyroidism is an Independent Risk Factor for Extreme Blood Pressure Dipping during Sleep: an Analysis by Propensity Score Matching
2B, p. 131 2023 - Circulation
CAMPOS-STAFFICO AM, Dorsch MP, Barnes G, Zhu H, Limdi NA, Luzum JA Eight Pharmacokinetic-Related Genetic Variants Were Not Associated With Bleeding From Direct Oral Anticoagulants in Non-Valvular Atrial Fibrillation Patients 2022 - Circulation
CAMPOS-STAFFICO AM, Dorsch MP, Barnes G, Luzum JA Nonspecific Tools Performed Better in Discriminating Major Bleeding From Direct Oral Anticoagulants Than Specific Tools in a Real-World Population With Atrial Fibrillation 2022 - Pharmacogenomics Global Research Network-American Society of Human Genetics
CAMPOS-STAFFICO AM, Edwards A, Hanigan S, Pogue K, Dorsch MP, Luzum JA ABCB1 Diplotype is Associated with Bleeding from Rivaroxaban, p. 102 2021 - J Am Coll Clin Pharm
CAMPOS-STAFFICO AM, Cordwin D, Ding Y, Lester C, Brook RD, Luzum JA, Dorsch MP Fewer Patients Receive Recommendations for Primary Drug Prevention Using the 2018 Atherosclerotic Cardiovascular Disease Risk Estimator
8, p. 1540-1541 2020 - Rev Soc Cardiol Estado de São Paulo
CAMPOS AM, Freitas WM, Nóbrega OT, Sposito AC Bone Effects of Statins are Associated with Reduced Subclinical Atherosclerosis in Very Elderly Individuals
2B, p. 149 2017 - Rev Soc Cardiol Estado de São Paulo
CAMPOS AM, Costa APR, Figueiredo VN, Silva JCQ, Sposito AC Effects of the Previous Intake of Omega-3 on the Inflammatory and Endothelial Response of Individuals with STEMI
2B, p. 171 2017 - Rev Soc Cardiol Estado de São Paulo
CAMPOS AM, Freitas WM, Sposito AC Effects of Statins on Body Composition and Functional Assessment of Very Elderly Individuals
2B, p. 114 2016 - Rev Soc Cardiol Estado de São Paulo
Sposito AC, Silva JCQ, Carvalho LSF, CAMPOS AM, Barbosa MA Family Income is an Independent Risk Factor for a Worse Prognosis After Acute Myocardial Infarction
2B, p. 185 2016 - Rev Soc Cardiol Estado de São Paulo
CAMPOS AM, Sposito AP, Freitas WM, Sposito AC Biosocial Factors and Acute Myocardial Infarction in Very Elderly Patients
2B, p. 128 2015 - Rev Soc Cardiol Estado de São Paulo
Sposito AP, CAMPOS AM, Freitas WM, Sposito AC Depressive Symptoms and Risk of Myocardial Infarction in Very Elderly Patients
2B, p. 236 2015 - Rev Soc Cardiol Estado de São Paulo
Ramos SCL, Soares RV, Domingues PHF, CAMPOS AM Effects of Pharmaceutical Care on Adherence to the Treatment of Cardiac Patients, p. 41 2014 - J Hypert
CAMPOS AM, Mendes LF, Ribeiro AM, Neves FAR Human Prorenin is Internalized by Cardiomyocytes and Activates Signaling Pathway Involved in Ventricular Hypertrophy
S73 2004