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Nikhil Jagan, MB,BS

Assistant Professor

Contact

School of Medicine
Department of Medicine
Pulmonary, Critical Care, and Sleep Medicine
Critical Care Medicine Fellowship
Pulmonary and Critical Care Fellowship
CUMC - Creighton University Medical Center - Suite 401, Creighton Education Bldg

Nikhil Jagan, MB,BS

Assistant Professor

Board Certified in Internal Medicine, Pulmonary Disease

Areas of Interest: Bronchoscopy, Lung Cancer Diagnoses, Cardiac Arrest Simulation Training, Quality Improvement, Critical Care Medicine
Pulmonary and Critical Care Fellowship: Creighton University, Omaha, NE
Residency: Creighton University, Omaha, NE
Medical School: Kasturba Medical College, Mangalore, India

Teaching Interests

  • Sepsis and Outcomes

Department

Medicine

Position

Assistant Professor

Articles

  • Pharmacotherapy Principles and Practice 6 th Edition.
    Jagan N, Morrow L, Malesker M Matthias KR, Katz MD eds. Pharmacotherapy Principles and Practice Study Guide: A Case Based Care Plan Approach, 6th ed. New York: McGraw Hill Medical; 2023. ISBN 978-1-264-27891-6. Jagan N, Morrow L, Malesker M. Euvolemic Hyponatremia 2023
  • Respiratory Care
    Jagan, N., A Retrospective Analysis of the Effects of TIME on Compliance and Driving Pressures in Acute Respiratory Distress Syndrome: The TIMED Study. Respiratory Care. 2022 June 15. Jagan, N., Morrow, L.E., Walters, R.W., Plambeck, R.W., Ng, I., Chovatiya, J.J., & Maleskar, M.A. 2022
  • Annals of the American Thoracic Society
    Jagan, N, Uncovering Objective Improvements in Physical Activity Using Digital Actigraphy After Therapeutic Thoracentesis: A Pilot Study. Jagan, N., Walters RW, Maldonado, F., Pilli, S., DePew ZS. Annals of the American Thoracic Society. 2022 May 19 2022
  • Chest
    Rampon, G, Smartphone-guided Self-prone Positioning Versus Usual Care in Non-Intubated Hospital Ward Patients with COVID-19: A Pragmatic Randomized Clinical Trial. Rampon, G., Jil, S., Agrawal, R. Arnold, N., Martin-Quiros, A., Fischer, EA, Malatack, J., Jagan, N., Sergew, A., Case, AH, Miller, K. Chest 2022 May 18. 2022
  • Ann Am Thorac Soc
    Garcia, MA, Rampon GL, Doros G, Jia S, Jagan N, Gillmeyer K, Berical A, Hudspeth J, Ieong M, Modzelewski KL, Schechter-Perkins EM, Ross CS, Rucci JM, Simpson S, Walkey AJ, Bosch NA Rationale and Design of the Awake Prone Position for Early Hypoxemia in COVID-19 (APPEX-19) Study Protocol. Garcia MA, Rampon GL, Doros G, Jia S, Jagan N, Gillmeyer K, Berical A, Hudspeth J, Ieong M, Modzelewski KL, Schechter-Perkins EM, Ross CS, Rucci JM, Simpson S, Walkey AJ, Bosch NA.Ann Am Thorac Soc. 2021 Mar 1. doi: 10.1513/AnnalsATS.202009-1124SD. Online ahead of print.PMID: 33647225 2021
  • Annals of Intensive Care
    Jagan N, Morrow LE, Walters RW, Plambeck RW, Patel TM, Moore DR, Malesker MA. Sympathetic stimulation increases serum lactate concentrations in patients admitted with sepsis: implications for resuscitation strategies. Annals of intensive care. 2021 Feb 5;11(1):24.
    11(1), p. :24. 2021
  • The Senior Care Pharmacist
    Christensen KJ, Malesker MA, Jagan N, Moore DR. Pulmonary Manifestations of Rheumatoid Arthritis. The Senior Care Pharmacist. 2021 Feb 1;36(2):97-103.
    36(2), p. 97-103 2021
  • Chest
    Jagan N, Morrow LE, Walters RW, Plambeck RW, Patel TM, Kalian KF, Macaraeg JC, Dyer ED, Bergh AA, Fried AJ, Moore DR. Sepsis, the Administration of Intravenous Fluids and Respiratory failure: A Retrospective analysis-SAIFR Study. Chest. 2020 Nov 14 2020
  • Critical Care Explorations
    Jagan N, Morrow LE, Walters RW, Klein LP, Wallen TJ, Chung J, Plambeck RW. The POSITIONED Study: Prone Positioning in Nonventilated Coronavirus Disease 2019 Patients—A Retrospective Analysis. Critical Care Explorations. 2020 Oct 1;2(10):e0229
    2(10), p. e0229 2020
  • Crit Care Med
    Jagan N, Morrow L, Walters R, Plambeck R, Wallen T, Patel T, Malesker M, Sepsis and the Obesity Paradox: Size Matters in More Than One Way. Critical Care Medicine. 2020 Jul 21. 2020
  • Case Reports in Pulmonology
    Essa A, Macaraeg J, Jagan N, Kwon D, Randhawa S, Kruse M, Thomas S, Velagapudi M, Horne J, Narechania S, Kaster M. Review of Cases of ECigarette or Vaping Product Use-Associated Lung Injury (EVALI) and Brief Review of the Literature. Case Reports in Pulmonology. 2020 Jun 15;2020. 2020
  • Chest
    The Impact of Gravity vs Suction-driven Therapeutic Thoracentesis on Pressure-related Complications: The GRAVITAS Multicenter Randomized Controlled Trial.Lentz RJ1, Shojaee S2, Grosu HB3, Rickman OB4, Roller L5, Pannu JK6, DePew ZS7, Debiane LG8, Cicenia JC9, Akulian J10, Walston C4, Sanchez TM2, Davidson KR2, Jagan N7, Ahmad S11, Gilbert C12, Huggins JT13, Chen H14, Light RW5, Yarmus L15, Feller-Kopman D15, Lee H15, Rahman NM16, Maldonado F17; Interventional Pulmonary Outcomes Group.PMID 31711990 2019
  • Journal of Thoracic Disease
    Waste not, want not: diagnostic material found in suction syringe aspirate during endobronchial ultrasound guided transbronchial needle aspiration.Jagan N1, Landeen CA1, Moore DR1, Highley AD1, Walters RW2, DePew ZS1.PMID:31559029 
    11;8 2019
  • Journal of Pharmacy Practice
    Dull S, Jagan N, Moore D, DePew Z, Morrow L, Malesker M. Diffuse Alveolar Hemorrhage Following Pirfenidone Initiation. 2019
  • Respirartory Medicine Case Reports
    Wallen T, Jagan N, Krishnan M, DePew ZS. A 75 Year Old Male with Recurrent Unilateral Pleural Effusion and Positive ANA.
    26, p. 301-303 2019
  • Journal of Thoracic Disease
    Jagan N, Landeen CA, Moore DR, Highley AD, DePew ZS. Diagnostic Material Found in Suction Syringe Aspirate During Endobronchial Ultrasound Guided Transbronchial Needle Aspiration – Journal of Thoracic Disease 2019 2019
  • Respirartory Medicine Case Reports
    Wallen T, Jagan N, Krishnan M, DePew ZS. A 75-Year-Old Male with Recurrent Unilateral Pleural Effusion and Positive ANA. Respiratory Medicine Case Reports 2019:26:301-303.
    26, p. 301-303. 2019
  • CHI Health Better You Blog
    Jagan N, DePew Z. Lung Cancer Screening, the Effects of Radon, and Lung Cancer in Farmers. 2018
  • ATS Quick Hits
    Jagan N, Morrow L. Asymptomatic Pneumoperitoneum-Is this possible? 2018
  • Journal of Pharmacy Technology
    Ajimura C, Jagan N, Morrow L, Malesker M. Drug Interactions with Oral Inhaled Medications.
    34(6), p. 273-280 2018
  • Journal of Pharmacy Technology
    Ajimura C, Jagan N, Morrow L, Malesker M. Drug Interactions with Oral Inhaled Medications.Journal of Pharmacy Technology 34 (6), 273-280
    34, p. 273-280 2018
  • Journal of Thoracic Disease
    Jagan N, Landeen CA, Moore DR, Highley AD, DePew ZS. Diagnostic Material Found in Suction Syringe Aspirate During Endobronchial Ultrasound Guided Transbronchial Needle Aspiration
  • Critical Care Medicine
    Jagan N, Morrow L, Walters R, Plambeck R, Moore D, Patel T, Malesker M. Sympathetic Stimulation increases Serum Lactate Concentration in Patients Admitted with Sepsis: Implications for Resuscitation Strategies.
  • Respirartory Medicine Case Reports
    Kumar M, Jagan N, Krishnan M, Rashmi P, DePew Z. Concurrently Existing Sarcoidosis and Lymphoma - A Rare Variant of Sarcoid Lymphoma Syndrome.

Publications

  • Crit Care Med
    Rajendraprasad, S, Ahmad F, Loranger A, Pruett W, Kessel B, Jagan N, Boldt D, Schmidt D, Hayes S, Anthone J, Vivekanandan R, Quimby D, Velagapudi M, Krajicek B, Destache C: Rajendraprasad S, Ahmad F, Loranger A, Pruett W, Kessel B, Jagan N, Boldt D, Schmidt D, Hayes S, Anthone J, Vivekanandan R, Quimby D, Velagapudi M, Krajicek B, Destache C: COVID-19 Therapeutics: What Works?, Critical Care Medicine: January 2021 - Volume 49 - Issue 1 - p 93 doi: 10.1097/01.ccm.0000726752.78687.16 2021
  • Crit Care Med
    Ahmad F, Rajendraprasad S, Loranger A, Pruett W, Kessel B, Jagan N, Boldt D, Schmidt D, Hayes S, Anthone J, Vivekanandan R, Quimby D, Velagapudi M, Krajicek B, Destache C Ahmad F, Rajendraprasad S, Loranger A, Pruett W, Kessel B, Jagan N, Boldt D, Schmidt D, Hayes S, Anthone J, Vivekanandan R, Quimby D, Velagapudi M, Krajicek B, Destache C: Influence of Health Disparities on COVID-19 Critical Care Admissions. Critical Care Medicine: January 2021 - Volume 49 - Issue 1 - p 101 doi: 10.1097/01.ccm.0000726812.53135.52
    49 2021
  • Chest
    Jagan N, Morrow L, Walters R, Plambeck R, Moore D, Patel T, Malesker M. Sympathetic Stimulation Increases Serum Lactate Concentration in Patients Admitted with Sepsis: Implications for Resuscitation Strategies. 2019
  • Chest
    Jagan N, Morrow L, Walters R, Wallen T, Malesker M. Sepsis and the Obesity Paradox: Size matters in more than one way.  2019
  • Critical Care Medicine
    Gorantla R, Jagan N, Moore D, Berim I, Maki S. Organizing Pneumonia and Massive Hemoptysis: Rare but potentially fatal.
    47(1), p. 567 2019
  • Chest
    Jagan N, Krishnan M, Malesker M, Sanley M. Acute Pulmonary Embolism Following Two Doses of Intravenous Conjugated Estrogen.
    154(4), p. 832a 2018
  • American Journal of Respiratory and Critical Care Medicine
    Krishnan M, Jagan N, DePew ZS. A Dilemma in the Etiology of Serositis.
    197, p. A3215 2018
  • American Journal of Respiratory and Critical Care Medicine
    Berim I, Landeen C, Jagan N, King A. Blood patch impact on Pneumothorax risk during Electromagnetic Navigation bronchoscopy.
    197 2018
  • American Journal of Respiratory and Critical Care Medicine
    Jagan N, Landeen C, Munir A, Plambeck R. Total Pleural Nutrition - A Rare Complication of Central Line Placement.
    197 2018
  • American Journal of Respiratory and Critical Care Medicine
    Nayfeh A, Addasi N, Jagan N, Macaraeg J, Berim I. Rapidly Fatal Anti Synthetase Syndrome presenting with Pneumonia.
    197 2018
  • American Journal of Respiratory and Critical Care Medicine
    Berim I, Colanta A, Saeed I, Jagan N, Landeen C, King A. Contamination of needles used for endobronchial ultrasound guided biopsies: myth confirmed.
    195, p. A2868 2017
  • Chest
    Jagan N, Mourya R, Wichman C, Bell D, Morrow L. The Natural History and Clinical Relevance of Colonization with Methicillin-Resistant Staphylococcus aureus (MRSA).
    150(4), p. 147A 2016

Presentations

  • Toth S, Plambeck R, Jagan N. Respiratory failure due to Triple Overlap Syndrome in a young woman with Obesity. Accepted at ATS 2023 2023
  • Cardiopulmonary resuscitation through the ages - 17th Annual Pulmonary, Critical Care and Sleep Medicine Conference- Omaha, NE, October 2021 2021
  • Sepsis- Family Medicine Residency program lecture series at Creighton University - Omaha, NE, September 2021 2021
  • Cardiopulmonary resuscitation through the ages Pulmonary and Critical care Grand rounds at Creighton University - Omaha, NE, September 2021 2021
  • Society of Critical Care Medicine - Panelist on expert panel series for Critical Care for Non-ICU clinicians caring for critically ill COVID-19 patients, April 2021 2021
  • Society of Critical Care Medicine - Micro Learning presentation for awake prone positioning in COVID 19, March 2021 2021
  • Current and Evolving Standards in ARDS Pulmonary and Critical care Grand rounds at Creighton University - Omaha, NE, February 2021 2021
  • - Winter is Here- Continuing Medical Education at CHI Health St. FrancisGrand Island, NE, November 2020 2020
  • The Past, Present and the Future of the ICU - 16th Annual Pulmonary, Critical Care and Sleep Medicine Conference- Omaha, NE, September 2020 2020
  • Rib Fractures and the Lung: Trauma Grand Rounds at CHI Health St. Francis- Grand Island, NE, March 2020 2020
  • Jagan N, Landeen C, Walters R, Moore D, Highley A, DePew Z. "Waste Not, Want Not": Diagnostic material found in the suction syringe. 2nd Annual AABIP. Denver, CO. 2019
  • Jagan N, Krishnan M, Moore D, Plambeck R, Malesker M. "Thrombosis Secondary to Angiotensin II Infusion." ACCP Virtual Poster Symposium. 2019
  • Addasi N, Jagan N, Nayfeh A, DePew Z, Moore D. "A Challenging Case of Disseminated Sarcoidosis." American Thoracic Society Annual Conference. Dallas, TX. 2019
  • "Code Blue Training - A Multidisciplinary Approach." Creighton University School of Medicine QI Symposium. Omaha, NE. 2019
  • "Airway Management: Is there a role for Direct Laryngoscopy?" 15th Annual Pulmonary, Critical Care and Sleep Medicine Conference. Omaha, NE. 2019
  • "CIWA: The Ultimate Guide." Intensive Care Unit, Creighton University, Bergan Campus. Omaha, NE. 2019
  • "Organizing Pneumonia and Massive Hemoptysis: Rare But Potentially Fata." SCCM. San Diego, CA. 2019
  • Jagan N, Morrow L, Walters R, Plambeck R, Moore D, Patel T, Malesker M. Sympathetic Stimulation increases Serum Lactate concentration in patients admitted with Sepsis: Implications for Resuscitation Strategies. Presented at CHEST 2019 2019
  • Macaraeg J, Jagan N, Gupta V, Berim I. "Oxygen Transport in a Hospital Setting." Society of Critical Care Medicine Quality Summit. Atlanta, GA. 2018
  • "Delirium and the ICU." Intensive Care Unit, Creighton University, Bergan Campus. Omaha, NE. 2018
  • Krishnan M, Jagan N, Depew Z. "A Dilemma in the Etiology for Serositis." American Thoracic Society Annual Conference. San Diego, CA. 2018
  • Berim I, Colanta A, Jagan N, Landeen C, King A. "Optimization of Endobronchial Ultrasound Guided Needle Biopsies Using a 19G Needle: Go Bigger." American Thoracic Society Annual Conference. San Diego, CA. 2018
  • Berim I, Landeen C, Jagan N, King A. "Blood Patch Impact on Pneumothorax Risk During Electromagnetic Navigation Bronchoscopy." American Thoracic Society Annual Conference. San Diego, CA. 2018
  • Jagan N, Landeen C, Munir A, Plambeck R. "Total Pleural Nutrition - A Rare Complication of Central Line Placement." American Thoracic Society Annual Conference. San Diego, CA. 2018
  • Nayfeh A, Addasi N, Jagan N, Macaraeg J, Berim I. "Rapidly Fatal Anti Synthetase Syndrome Presenting with Pneumonia." American Thoracic Society Annual Conference. San Diego, CA. 2018
  • "Update on Sepsis." Cardiovascular and Pulmonary Forum. Omaha, NE. 2018
  • "Lung Cancer: The Era of Targeted Therapy and Immunotherapy." Pulmonary and Critical Care Grand Rounds, Creighton University. Omaha, NE. 2018
  • "Improving Resident Education in Critical Care Procedures, A Quality Improvement Project." Creighton University School of Medicine QI Symposium. Omaha, NE. 2018
  • "Update on Sepsis." 14th Annual Pulmonary, Critical Care and Sleep Medicine Conference. Omaha, NE. 2018
  • "Nuts and Bolts of the Management of ARDS for Nursing and Respiratory Therapy." Intensive Care Unit, Creighton University, Bergan Campus, Omaha, NE. 2017
  • Intraosseous placement simulation and training for Internal Medicine residents. Creighton University. Omaha, NE. 2017
  • "Improving Enteral Nutrition Delivery in Critically Ill Patients, A Quality Improvement Project." Creighton University School of Medicine QI Symposium. Omaha, NE. 2017
  • "Conventional and Unconventional Uses of Endobronchial Ultrasound." Pulmonary and Critical Care Grand Rounds, Creighton University. Omaha, NE. 2017
  • "The Natural History and Clinical Relevance of Colonization with Methicillin-Resistant Staphylococcus aureus (MRSA)." CHEST. Los Angeles, CA. 2016
  • "Bedside Ultrasound Enhancing Patient Care." Internal Medicine Grand Rounds, Creighton University. Omaha, NE. 2016
  • Jagan N, Anathanarayanan M, Khanal N, Wichman T. "Nonspecific Interstitial Pneumonia with Progression to Diffuse Micronodules in an Individual with a History of Malignancy: What Are the Possibilities?" American Thoracic Society Annual Conference. San Francisco, CA. 2016
  • "Surrogate Decision Making - A challenge in clinical medicine." Internal Medicine Grand Rounds, Creighton University. Omaha, NE. 2015
  • Nawaz S, Haddad T, Vallabhajosyula S, Jagan N, Jagadesh S. "Capnocytophagia Sepsis: A rare disease." Society of General Internal Medicine. Toronto, CA. 2015
  • Jagan N, Tella H, Brannan T. "Patient Education - A Case of NSAID Induced Acute Tubular Necrosis." Society of General Internal Medicine. San Diego, CA. 2014

Other

  • Travel Grant to ATS 2016

Awards

  • Alfred Brody Collegiate Professorship Award 2022-2023
    Creighton University's Alfred Brody College Professorship Award 2022-2023
    Creighton University
  • Nomination: Common Spirit Health Physician Enterprise Vision Award
    Nomination Common Spirit Health Physician Enterprise Vision Awards – Inspiration Category 2022
    Common Spirit Health
  • George F.Haddix Grant recipient
    George F.Haddix Grant recipient (June 1st 2020 to May 31st 2021) for the TIME TO MOVE Study
    George F.Haddix Grant
  • Admiral State of Nebraska
    Admiral State of Nebraska- Awarded by Gov Pete Ricketts on 6/2/2020
    Gov Pete Ricketts
  • Outstanding Fellow Award
    Exemplifying Academic Leadership in Resident Education
    Creighton University Internal Medicine Residency Program
  • Alignment with the Mission of Creighton University Award
    Code Blue Training - A Multidisciplinary Approach
    GME Annual QI Symposium
  • Best Poster Award
    Standardization of Post Code Debrief
    GME Annual QI Symposium
  • Nomination Physician Excellence Award
    Nomination Physician Excellence Award, CHI Health St. Francis Medical Center 2019 - 2020
    CHI Health St. Francis Medical Center
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