Jeffrey C. Macaraeg, MD

Department

Medicine

Position

Assistant Professor

Articles

• US Pharmacist
  Tarpey, A, Macaraeg, J., Morrow, L, Maleskar, M Drug Interactions with Interstitial Lung Disease Pharmacotherapy. U.S Pharmacist The Pharmacist’s Resource for Clinical Excellence. July 2022.
  47, p. HS7-HS12 2022
• Respiratory Care
  Jagan, N, Morrow, L; Walters, R., Plambeck, R., Ng, I, Chovatiya, J, Macaraeg, J; Kalian, K., Wittenberg, Z., Pruett, W., Knedler, J., Klein, L., Kasinath, P., Dyer, E., Bergh, A., Malesker, M A Retrospective analysis of the effects of TIME on Compliance and Driving pressures in acute respiratory distress syndrome: The TIMED study. Respir Care. 2022 Jun 15
  68, p. 52-59 2022
• The Lancet
  Wolfe, C, Baricitinib versus dexamethasone for adults hospitalized with Covid-19 (ACTT-4): A randomized, double-blind, double placebo-controlled trial. The Lancet Respiratory Medicine. May 23, 2022. 2022
• McGraw-Hill
  Macaraeg, Jeffrey, Macaraeg, J., Morrow, L.E., and Malesker, M.A.: Hyperkalemia (Chapter 30). In Katz, M.D., Matthias, K.R., Chisholm-Burns, M.A. Pharmacotherapy Principles & Practice Study Guide: A Case-Based Care Plan Approach, 5th edition, New York: McGraw-Hill, Published 2022 2022
• Case Reports in Pulmonology
  Essa A, Macaraeg J, Jagan N, Kwon D, Randhawa S, Kruse M, Thomas SV, Velagapudi M, Horne J, Narechania S, Kaster M, Valenta C, Shasranaman V, Moore D Review of Cases of E-cigarette or Vaping Product Use Associated Lung Injury (EVALI) and Brief Review of The Literature Case Reports in Pulmonology, Volume 2020 Article ID 1090629 Hindawi
  2020 2020
• Chest
  'Sepsis, the Administration of Intravenous Fluids and Respiratory failure: A Retrospective analysis - SAIFR Study.' CHEST 2020 2020
• Case Reports in Pulmonology-Hindawi
  Review of Cases of E-cigarette or Vaping Product Use Associated Lung Injury (EVALI): A Mini Case Series and Brief Review of The Literature. Case Reports in Pulmonology-Hindawi. 2020; 1090629, Pg. 7
  1090629, p. 7 2020
• Wisconsin Medical Journal
  A Case Report on Suspected Levamisole-Induced Pseudo vasculitis. Wisconsin Medical Journal. 2017; 116(1): 37-39.
  116(1), p. 37-39. 2017
• Infection Control & Hospital Epidemiology
  Evaluation of Staphylococcus aureus Bacteremia: Academic and Community-Based Management within the Same Health System. Infection Control and Hospital Epidemiology. 2017; 38(6)740-742.
  38(6), p. 740-742. 2017

Publications

• Chest
  Lethal Fungemia in Covid-19 Pneumonia. Presented by A.K Plemmons at Chest October 2021 ANNA PLEMMONS, WILLIAM PRUETT, JEFFREY MACARAEG, Chest,Volume 160, Issue 4, Supplement, 2021, Page A430, ISSN 0012-3692, https://doi.org/10.1016/j.chest.2021.07.425. 2021
• American Journal of Respiratory and Critical Care Medicine
  Bronchoscopic Evaluation of Hemoptysis: An Unusual Day at the Zoo. American Journal of Respiratory and Critical Care Medicine 2020; 201: A3914
  201, p. A3914 2020
• American Journal of Respiratory and Critical Care Medicine
  Endobronchial Lipoma: A Rare Cause for a Recurrent Presentation. American Journal of Respiratory and Critical Care Medicine 2020; 201: A3180
  201, p. A3180 2020
• American Journal of Respiratory and Critical Care Medicine
  Hemodynamically unstable narrow complex tachycardia caused by intracardiac migration of ventriculo-peritoneal shunt catheter. American Journal of Respiratory and Critical Care Medicine 2020; 201: A3416
  201, p. A3416 2020
• Critical Care Medicine
  A Rare Case of Human Enterovirus-Rhinovirus Associated Acute Respiratory Distress Syndrome in a 51-year-old Female. Critical Care Medicine. January 2019. 47(1):528.
  47(1), p. 528. 2019
• Critical Care Medicine
  Mixed Connective Tissue Disease Presenting as Severe Pulmonary Artery Hypertension in a 27-year-old Hispanic female. Critical Care Medicine. January 2019. 47(1):564.
  47(1), p. 564 2019
• Critical Care Medicine
  Impact of Anemia on Mortality of Patients with Acute COPD exacerbation. Critical Care Medicine. January 2019. 47(1):525.
  47(1), p. 525. 2019
• Critical Care Medicine
  Code Sepsis: We’re on the Clock. Critical Care Medicine. January 2019. 47(1):636.
  47(1), p. 636 2019

Presentations

• Grand Rounds: eICU Performance Metrics; February 10, 2023 2023
• Family Medicine Residency Program lecure: COPD 1/27/23 2023
• Evaluation of IV Fentanyl Infusion Dose in the Intensive Care Unit. Presented at SCCM Congress 2023; San Francisco, Ca 1/2023 2023
• Fusarium oxysporum-Induced Acute Respiratory Distress Syndrome in an Immunocompetent Host. Presented at SCCM Congress 2023; San Francisco, Ca 1/2023 2023
• Fundamental Critical Care Support : Midlands Hospital, September 27, 2022; Life Threatening Infections: Diagnosis and Antimicrobial therapy selection- 1 hour Cardiopulmonary/Cerebral Resuscitation - 1 hour 2022
• Improving PPI use during hospital admission into the ICU. Presented at Creighton University School of Medicine GME QI Symposium; Omaha, Ne May 2022 2022
• A retrospective analysis of the effects of TIME on Compliance and Driving pressures in acute respiratory distress syndrome: The TIMED study. Nikhil Jagan et al. Outstanding Research Project 2/22 GME Research Symposium. 2022
• Grand Rounds: Post Intensive Care Syndrome; January 14, 2022 2022
• Lethal Fungemia in Covid-19 Pneumonia. Presented by A.K Plemmons at Chest October 2021 2021
• Improving Lung Cancer Screening. Presented at Creighton University School of Medicine Graduate Medical Education Quality Improvement Symposium; Omaha, Ne, May 2020. 2020
• Code Simulation. Presented by Jagan N, at Creighton University School of Medicine Graduate Medical Education Quality Improvement Symposium; Omaha, Ne May 2019 2020
• Bronchoscopic Evaluation of Hemoptysis: An Unusual Day at the Zoo. ATS May 2020. 2020
• Hemodynamically unstable narrow complex tachycardia caused by intracardiac migration of ventriculo-peritoneal shunt catheter. Presented by Sharma, A at ATS May 2020. 2020
• Endobronchial Lipoma: A Rare Cause for a Recurrent Presentation. Presented by Nayfeh, A at ATS May 2020 2020
• Importance of Lower Respiratory Tract Samples for Diagnosis of Coronavirus Disease 2019 (COVID-19). CHEST 2020 2020
• Code Blue Simulation. Presented at Creighton University School of Medicine GME QI Symposium; Omaha, Ne May 2019 2019
• Quality Improvement Curriculum in Internal Medicine Residency at Creighton University. Presented by Jhand A at High Value Practice Academic Alliance National Conference, Baltimore, Md 2019. 2019
• A Rare Case of Human Enterovirus-Rhinovirus Associated Acute Respiratory Distress Syndrome in a 51-year-old Female. Presented by Parekh J at SCCM 2019. 2019
• Impact of Anemia on Mortality of Patients with Acute COPD exacerbation. SCCM 2019 2019
• Code Sepsis: We're on the Clock. SCCM 2019 2019
• Quality Improvement Curriculum in Internal Medicine Residency at Creighton University. HVPAA Poster Presentation 2019. 2019
• Mixed Connective Tissue Disease Presenting as Severe Pulmonary Artery Hypertension in a 27-year-old Hispanic female. SCCM 2019 2019
• Rapidly Fatal Anti Synthetase Syndrome Presenting with Pneumonia. American Thoracic Society Poster Presentation, San Diego, Ca May 2018 2018
• Oxygen Transport. Presented at Creighton University School of Medicine GME QI Symposium; Omaha, Ne May 2018 2018
• Quality Improvement Curriculum in Internal Medicine Residency at Creighton University. Presented by Gupta V at High Value Practice Academic Alliance, Baltimore, Md 2018. 2018
• Oxygen Transport. SCCM Quality Summit; Atlanta, Ga September 2018 2018
• Rapidly Fatal Anti Synthetase Syndrome Presenting with Pneumonia. ATS Poster Presentation, San Diego, Ca May 2018. 2018
• Quality Improvement Curriculum in Internal Medicine Residency at Creighton University. HVPAA Poster Presentation 2018. 2018
• Slam Dunk - Presumed Bactrim induced Nephropathy. SHM Poster Presentation 2017 2017
• Oxygen Transport. Presented at Creighton University School of Medicine GME QI Symposium; Omaha, Ne May 2017 2017
• A Case of Microscopic Polyangiitis complicated by Diffuse Alveolar Hemorrhage. SHM Poster Presentation 2017. 2017
• A Comparison of Staphylococcus aureus Bacteremia (SAB) Diagnosis and Management: Differences Between Academic and Community Hospital Settings. Presented by Ased S, at ID Week, New Orleans, LA, 2016 2016

Industry/Corporation

• Lungpacer. “A Protocol Comparing Temporary Transvenous Diaphragm Pacing to Standard of Care for Weaning from Mechanical Ventilation in ICU Patients.” RESCUE-3
  a. Sub-investigator

• Grifols Therapeutics LLC “A Multicenter, Randomized, Open-label Parallel Group Pilot Study to Evaluate Safety and Efficacy of High Dose Intravenous Immune Globulin (IVIG) plus Standard Medical Treatment (SMT) versus SMT alone in Subjects with COVID-19 Requiring Admission to the Intensive Care Unit”
  a. Sub-investigator

• Incyte Corp. “An Open-Label Expanded Access Program of Ruxolitinib for the Emergency Treatment of Cytokine Store from Covid –19 Infection.
  a. Principal Investigator

• National Institute of Allergy and Infectious Diseases (NIAID) 20-0006. “Randomized, double-blind, placebo-controlled to evaluate the safety and efficacy of novel therapeutic agents in hospitalized adults diagnosed with COVID-19. Adaptive COVID-19 Treatment Trial 4 (ACTT-4)”
  a. Principal Investigator

• InsMed INS-415: ARISE – A Randomized, Double-Blind, Placebo-Controlled, Active Comparator, Multicenter Study to Validate Patient-Reported Outcome Instruments in Adult Subjects with Newly Diagnosed Nontuberculous Mycobacterial (NTM) Lung Infection Caused by Mycobacterium avium Complex (MAC)
  a. Sub-Investigator

• InsMed INS-416: ENCORE – A Randomized, Double-Blind, Placebo-Controlled, Active Comparator, Multicenter Study to Evaluate the Efficacy and Safety of an Amikacin Liposome Inhalation Suspension (ALIS) – Based Regimen in Adult Subjects with Newly Diagnosed Nontuberculous Mycobacterial (NTM) Lung Infection Caused by Mycobacterium avium Complex (MAC)

• Galapagos GLPG1690-CL-303: “A Phase 3, randomized, double-blind, parallel-group, placebo-controlled multicenter study to evaluate efficacy and safety of two doses of GLPG1690 in addition to local standard of care for a minimum of 52 weeks in subjects with idiopathic pulmonary fibrosis”
  a. Sub-investigator

• The effects of Prophylactic scheduled Melatonin in Patients in the Intensive care unit in preventing ICU acquired Delirium
  a. Sub-investigator

• Novartis NCT04362137: “Phase 3 Randomized, Double-blind, Placebo-controlled Multi-center Study to Assess the Efficacy and Safety of Ruxolitinib in Patients With COVID-19 Associated Cytokine Storm (RUXCOVID)”
  a. Principal-Investigator

• CF-301-105: A Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy and Safety of a Single Dose of Exebacase in Adult Patients Receiving Standard of Care Antibiotics for the Treatment of Staphylococcus aureus Bloodstream Infections (Bacteremia) Including Right-Sided Endocarditis (2020- 2022)

• Contrafect CF301-102: “A Multicenter, Double-Blind, Randomized, Comparative Study of the Safety, Tolerability and Efficacy of CF-301 vs. Placebo in Addition to Standard of Care Antibacterial Therapy for the Treatment of Adult Patients with Staphylococcus aureus Bloodstream Infections (Bacteremia) Including Endocarditis”
  a. Sub-investigator

• Mayo Clinic: “US Expanded Access Program for Convalescent Plasma for the Treatment of Patients with Covid-19
  a. Local Principal-investigator

• Novartis CQAW039A2315: “A 2-treatment period, randomized, placebo-controlled, multicenter, parallel-group study to assess the safety of QAW039 when added to existing asthma therapy in GINA Steps 3, 4, and 5 patients with uncontrolled asthma”
  a. Sub-investigator

• Roche CP40617: “A Phase III, Randomized, Double-Blind, Placebo-Controlled, Multi-Center Study to Evaluate the Efficacy and Safety of Baloxavir Marboxil in Combination with Standard of Care Neuraminidase Inhibitor in Hospitalized Patients with Severe Influenza”
  a. Sub-investigator

• Boehringer Ingelheim 1305-0013: A randomized, double-blind, placebo-controlled parallel group study in IPF patients over 12 weeks evaluating the efficacy, safety and tolerability of BI 1015550 18 mg taken orally B.I.D.
  a. Sub-Investigator

• Shionogi 1713R2117: “An Open-label Study to Assess the Intrapulmonary Concentrations of Cefiderocol at Steady State in Hospitalized Subjects with Bacterial Pneumonia on Treatment with Standard of Care Antibiotics and requiring Mechanical Ventilation”
  a. Sub-investigator

• Takeda 2002: “A Phase 2b, Randomized, Multi-Center, Double-Blind Dose-Ranging Study to Assess the Efficacy, Safety and Pharmacokinetics of Intravenous TAK-954 In Critically Ill Patients with Enteral Feeding Intolerance”
  a. Sub-investigator

Other

• Merck MK-7264-030: “A Phase 3, Randomized, Double-Blind, Placebo-Controlled, 12-Month Study to Evaluate the Efficacy and Safety of MK-7264 in Adult Participants with Chronic Cough” (PN030)
  a. Sub-investigator

Awards

• Alpha Omega Alpha Honor Medical Society
  Alpha Omega Alpha Honor Medical Society- Fellow Member in Beta Chapter of Nebraska, 2020
  Beta Chapter of Nebraska
• Best Poster
  Graduate Medical Education Quality Improvement Symposium-Best Poster: Code Debrief 2019
  Graduate Medical Education Quality Improvement Symposium
• Best Presentation
  Graduate Medical Education Quality Improvement Symposium: Best Presentation: Code Simulation 2019
  Graduate Medical Education Quality Improvement Symposium
• American College of Chest Physicians Travel Grant
  American College of Chest Physicians Travel Grant Fellows Course 2019
  American College of Chest Physicians
• Pulmonary & Critical Care Quality Improvement Campion
  Pulmonary & Critical Care Quality Improvement Campion 2018-2020
  Pulmonary & Critical Care
• Best Poster
  Graduate Medical Education Quality Improvement Symposium-Best Poster: Oxygen transport 2018
  Graduate Medical Education Quality Improvement Symposium
• Travel Grant Fellows Course
  American College of Chest Physicians Travel Grant Fellows Course 2018
  American College of Chest Physicians