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Mark V. Reedy, PhD

Chair, Biology Department, College of Arts and Sciences

Associate Professor

Mark Reedy

Contact

mreedy@creighton.edu
College of Arts and Sciences
Graduate School
Neuroscience (Master of Science)
Biology
HLSB - Hixson Lied Science Building

Mark V. Reedy, PhD

Chair, Biology Department, College of Arts and Sciences

Associate Professor

I am interested in the factors that guide cell and tissue movements during embryonic development since his undergraduate days at the University of Kansas.  Much of my work has focused on a population of cells called neural crest cells and the mechanisms they use to follow the correct path as they migrate extensively throughout the early embryo.  More recently, I have been using avian embryos as a model system for studying the mechanisms behind nicotine-induced birth defects.  I  joined the Creighton faculty in 2001 and became department chair in 2009. Prior to that, I was a postdoctoral research fellow at The M.D. Anderson Cancer Center, and earned my Ph.D. from the University of California at Davis.  

Research Focus

cell and tissue differentiation and morphogenesis during vertebrate development

Department

Biology

Position

Associate Professor

Books

  • Prentice Hall
    R.J. Grebenok, T. Leustek, H. Nickla, G.J. Podgorski, M. Reedy and D.L. Welker. Student Handbook for Genes VIII: Questions, Problems, and Solutions. 2004

Articles

  • Anatomical Record
    Patterson, R. A.; Cavanaugh, A. M.; Cantemir, V.; Brauer, P. R.; Reedy, M. V. MT2-MMP Expression During Early Avian Morphogenesis. Anatomical record.
    296, p. 64-70 2013
  • Development Dynamics
    Heidenreich, D. J., Reedy, M. V., Brauer, P. R. Homocysteine enhances cardiac neural crest cell attachment in vitro by increasing intracellular calcim levels
    237, p. 2117-2128 2008
  • Molecular and Cellular Biology
    D. B. Gould, M.V. Reedy, L.A. Wilson, R.A. Smith, R.L Johnson and S. W. M. John. Mutant myocilin nonsecretion in vivo is not sufficient to cause glaucoma.
    26, p. 8427-8436 2006
  • Oxford University Press
    D.M. Parichy, M.V. Reedy, and C.A. Erickson. Regulation of Melanoblast Migration and Differentiation. Chapter 5 in The Pigmentary System: Physiology and Pathophysiology, 2nd ed. J.J. Nordlund et al., eds., p. 108-139 2006
  • Developmental Dynamics
    Cantemir, V., Cai, D. H., Reedy, M. V., Brauer, P. R. Tissue inhibitor of metalloproteinase-2 (TIMP-2) expression during cardiac neural crest cell migration and its role in proMMP-2 activation
    231, p. 709-719 2004
  • Development Dynamics
    B. J. Tierney, T. Ho, M.V. Reedy, and P. R. Brauer. Homocysteine inhibits neural crest cell formation and morphogenesis in vivo.
    229, p. 63-73 2004
  • Current Biology
    Cole, DG and Reedy, MV. Algal morphogenesis: How Volvox turns itself inside-out.
    13, p. R770-R772 2003
  • Gene Expression Patterns
    Reedy, MV; Johnson, RL; Erickson, CA. The expression patterns of c-kit and Sl in chicken embryos suggest unexpected roles for these genes in somite and limb development. Gene Expression Patterns.
    3, p. 53-58 2003
  • Molecular and Cellular Biology
    B.S. Kim, O.V. Savinova, M.V.Reedy, Y. Lun, L. Gan, S.I Tomarev, S.W.M. John, and R.L. Johnson. Targeted disruption of myocilin (MYOC) suggests that glaucoma-causing mutations of myocilin in humans are gain of function mutations.
    21, p. 7707-7713 2001
  • Development
    R. Kos, M.V. Reedy, R. Johnson, and C.A. Erickson. The winged helix transcription factor cFoxD3 is important for establishing the neural crest lineage and repressing melanogenesis.
    128, p. 1467-1479 2001
  • Developmental Dynamics
    M.V. Reedy, C. D. Faraco, and C. A. Erickson. Specification and migration of melanoblasts at the vagal level and in hyperpigmented Silkie chickens.
    213, p. 476-485 1998
  • Developmental Biology
    M.V. Reedy, C. D. Faraco, and C. A. Erickson. The delayed entry of thoracic neural crest cells into the dorsolateral path is a consequence of the late emigration of melanogenic neural crest cells from the neural tube.
    200, p. 234-246 1998
  • Current Topics in Developmental Biology
    C.A. Erickson and M.V. Reedy. Neural crest development: the interplay between morphogenesis and cell differentiation.
    40, p. 178-209 1998

Federal

  • National Institutes of Health. The role of TIMP-2 in neural crest pathfinding. 05/09-04/2014. J. Turpen, P.I. and M. V. Reedy, sub-contract P.I. Total subcontract award: $155,435.

Other

  • Creighton University Medical Center. Congenital neurocristopathies and nicotine. P.R. Brauer, P.I., M.V. Reedy, co-P.I., and D.D. Smith, co-P.I. 08/09-07/11. Total award: $79,088.

Awards

  • Robert F. Kennedy Memorial Award for Teaching Achievement
    Creighton University Students Union
  • Distinguished Service Faculty Award
    Creighton University
  • Service to Youth Award
    Bellevue Public Schools, Bellevue NE
  • College Award for Outstanding Major Advising
    College of Arts and Sciences