Dr. Litao Tao graduated from Tsinghua University with BS and MS, and then he went to University of Southern California for his PhD and postdoctoral training. In 2021, Dr. Tao joined the Department of Biomedical Sciences, Creighton University as an assistant professor. Dr. Tao’s research is focused on epigenetic transcriptional regulation in the inner ear during development, maturation and regeneration. His research work is supported by government agencies and private foundations, including NIH (NIDCD and NIGMS), State of Nebraska, Hearing Health Foundation, American Hearing Research Foundation, and Bellucci Depaoli Family Foundation. His group has collaborations with many researchers all over the world, and his lab is a member lab of Hearing Restoration Project Consortium.
Proceedings of the National Academy of Sciences - PNAS Wang Xizi, SoxC transcription factors shape the epigenetic landscape to establish competence for sensory differentiation in the mammalian organ of Corti 120:34, p. e2301301120 - e2301301120 2023
Aging Cell Sarkar A., STAT3 promotes a youthful epigenetic state in articular chondrocytes 22:2 2023
Frontiers in Molecular Neuroscience Tao L., CDK2 regulates aminoglycoside-induced hair cell death through modulating c-Jun activity: Inhibiting CDK2 to preserve hearing 15 2022
Advanced Healthcare Materials Wu S., Tri-Layered and Gel-Like Nanofibrous Scaffolds with Anisotropic Features for Engineering Heart Valve Leaflets 11:10 2022
Scientific Reports Jen H. -I, GFI1 regulates hair cell differentiation by acting as an off-DNA transcriptional co-activator of ATOH1, and a DNA-binding repressor 12:1 2022
Proceedings of the National Academy of Sciences of the United States of America Yu H. V., POU4F3 pioneer activity enables ATOH1 to drive diverse mechanoreceptor differentiation through a feed-forward epigenetic mechanism 118:29 2021
Developmental Cell Tao L., Enhancer decommissioning imposes an epigenetic barrier to sensory hair cell regeneration 56:17, p. 2471 2021
eLife Menendez L., Generation of inner ear hair cells by direct lineage conversion of primary somatic cells 9, p. 1 - 33 2020
Proceedings of the National Academy of Sciences of the United States of America Gnedeva K., Organ of Corti size is governed by yap/tead-mediated progenitor self-renewal 117:24, p. 13552 - 13561 2020
eLife Jen H. -I, Transcriptomic and epigenetic regulation of hair cell regeneration in the mouse utricle and its potentiation by Atoh1 8 2019
PLoS Genetics Salehi P., Role of Neuropilin-1/Semaphorin-3A signaling in the functional and morphological integrity of the cochlea 13:10 2017
Frontiers in Cellular Neuroscience Tao L., Early transcriptional response to aminoglycoside antibiotic suggests alternate pathways leading to apoptosis in sensory hair cells in the mouse inner ear 9 2015