EARLY CLOSURE MARCH 4 - Due to the forecast for severe winter weather, Creighton's Omaha campus will close at 7 P.M. this evening.
All in-person classes, clinics, and events, regardless of start time, are asked to end by 7 P.M. For those needing a shuttle, please visit my.creighton.edu for the most up-to-date maps and schedule. Shuttles will run until 8 P.M. this evening. We encourage you to be mindful of other closures or impacted services across the city as well.
Employees, including those classified as responsible for “essential operations” should review Creighton's Weather and Emergency-Related Absence Policy and work with your immediate supervisor on expectations for job functions during this curtailment of campus operations.
Please be take proper winter weather precautions throughout the day and contact public safety at 402.280.2911 for any emergencies.
Jee-Yeon Hwang, PhD, assistant professor of pharmacology and neuroscience, Holly Stessman, PhD, assistant professor of pharmacology and neuroscience, and Gopal Jadhav, PhD, assistant professor of pharmacology and neuroscience, all in the School of Medicine, received an $848,188 grant from the National Institutes of Health (NIH) and the National Institute of General Medical Sciences to study “TREM1 as a Novel Therapeutic Target for Global Ischemia Induced Neuroinflammation, Neuronal Death and Cognitive Deficits.”
The goal of the study is to identify therapeutic treatments for neurodegeneration and cognitive deficits associated with global cerebral ischemia – when blood flow to the brain is stopped or reduced – often triggered by cardiac arrest.
Some areas of the brain are highly susceptible to a lack of blood and oxygen supply, leading to long-term brain damage or dysfunction. One such area is the hippocampus, which has a crucial role in learning and memory. Even after recovery, memory loss and other cognitive dysfunctions may remain.
This NIH award aims to support the development of team science projects. In line with this objective, the research team consists of faculty with different expertise: Hwang, a neurobiologist; Jadhav, a medicinal chemist; and Stessman, a geneticist.
“The diverse expertise of our team enables us to collectively explore questions beyond the scope of our individual disciplines,” said Hwang. “This innovative team will provide synergistic collaboration to advance the understanding of the mechanisms underlying neuroinflammation in global ischemia pathology and, therefore, develop novel drugs to mitigate neurodegeneration and cognitive deficits following global ischemic insults.”