Jee-Yeon Hwang, PhD

Department

Pharmacology and Neuroscience

Position

Associate Professor

Book, Chapter/Section

• Stroke
  Zhang Haiyue, Zukin R. Suzanne, Ofengeim Dimitry, Shi Yejie, Chen Jun, Zhang Feng, Hwang Jee-Yeon, Molecular and Cellular Mechanisms of Ischemia-Induced Neuronal Death [Book Chapter] 2016

Publications

• Frontiers in immunology
  Bai Isaac, Zhang Ziyan, Keyser Cameron, Rosolia Breandan, Yan Jingqi, Hwang Jee-Yeon, Zukin R Suzanne, Epigenetic regulation of autophagy in neuroinflammation and synaptic plasticity
  15, p. 1322842 2024
• STAR protocols
  Kim Hyunha, Hwang Jee-Yeon, Urquhart Rachael, Pontarelli Fabrizio, Ofengeim Dimitry, Jover-Mengual Teresa, Protocol for establishing a global ischemia model using a 4-vessel occlusion in rats
  4:4, p. 102630 2023
• Cell reports (Cambridge)
  Chung Kyung Min, Kim Hyunha, Roque Cláudio Gouveia, Hengst Ulrich, McCurdy Ethan P., Nguyen Trang T.T., Siegelin Markus D., Hwang Jee-Yeon, A systemic cell stress signal confers neuronal resilience toward oxidative stress in a Hedgehog-dependent manner
  41:3, p. 111488 - 111488 2022
• Cell reports (Cambridge)
  Hwang Jee Yeon, Zukin R. Suzanne, Singer Robert H., Castillo Pablo E., Monday Hannah R., Yan Jingqi, Gompers Andrea, Buxbaum Adina R., Sawicka Kirsty J., CPEB3-dependent increase in GluA2 subunits impairs excitatory transmission onto inhibitory interneurons in a mouse model of fragile X
  39:10, p. 110853 - 110853 2022
• Frontiers in cellular neuroscience
  Jover-Mengual Teresa, Centeno José M., Hwang Jee-Yeon, Byun Hyae-Ran, Court-Vazquez Brenda L., Zukin R. Suzanne, Burguete María C., The Role of NF-κB Triggered Inflammation in Cerebral Ischemia
  15, p. 633610 2021
• Stroke (1970)
  Byun Hyae-Ran, Zukin R.Suzanne, Hwang Jee-Yeon, Court Vazquez Brenda L, Porch Morgan, Pontarelli Fabrizio, Abstract WP329: The Role of miR-34b/c in Global Ischemic Stroke
  51:Suppl_1 2020
• Current opinion in neurobiology
  Hwang Jee-Yeon, Yan Jingqi, Zukin Ruth Suzanne, Autophagy and synaptic plasticity: epigenetic regulation
  59, p. 207 - 212 2019
• IBRO reports
  Hwang Jee-Yeon, Byun Hyae-Ran, Porch Morgan, Pontarelli Fabrizio, Court-Vazquez Brenda, Zukin Suzanne R., miR-34b/c inhibition attenuates ischemia-induced death of hippocampal neurons and rescues aberrant synaptic plasticity and cognitive deficits
  6, p. S374 - S375 2019
• International neurourology journal
  Cho Chang Hoon, Zukin R. Suzanne, Hwang Jee-Yeon, Dejesus Christopher, Byun Hyae-Ran, Jover-Mengual Teresa, Pontarelli Fabrizio, Cho Ah-Rhang, Gadd45b Acts as Neuroprotective Effector in Global Ischemia-Induced Neuronal Death
  23:Suppl 1, p. S11 - S21 2019
• Current opinion in neurobiology
  Hwang Jee-Yeon, Zukin R Suzanne, REST, a master transcriptional regulator in neurodegenerative disease
  48, p. 193 - 200 2018
• Science signaling
  Pyronneau Alexander, Porch Morgan, He Qionger, Hwang Jee-Yeon, Contractor Anis, Zukin R. Suzanne, Aberrant Rac1-cofilin signaling mediates defects in dendritic spines, synaptic function, and sensory perception in fragile X syndrome
  10:504 2017
• Nature reviews. Neuroscience
  Hwang Jee-Yeon, Aromolaran Kelly A., Zukin R. Suzanne, The emerging field of epigenetics in neurodegeneration and neuroprotection
  18:6, p. 347 - 361 2017
• Cell death and differentiation
  Hwang Jee-Yeon, Ofengeim Dimitry, Gertner Michael, Pontarelli Fabrizio, Court-Vazquez Brenda, Bennett Michael Vander Laan, Zukin Ruth Suzanne, Global ischemia induces lysosomal-mediated degradation of mTOR and activation of autophagy in hippocampal neurons destined to die
  24:2, p. 317 - 329 2017
• Brain research
  Takeuchi Koichi, Bennett Michael V L, Zukin R Suzanne, Aromolaran Kelly, Yang Yupeng, Takayasu Yukihiro, Gertner Michael, Hwang Jee-Yeon, Estradiol pretreatment ameliorates impaired synaptic plasticity at synapses of insulted CA1 neurons after transient global ischemia
  1621, p. 222 - 230 2015
• Journal of molecular biology
  Hwang Jee Yeon, Noh Kyung Min, Pontarelli Fabrizio, Zukin R. Suzanne, Kaneko Naoki, The gene silencing transcription factor rest represses miR-132 expression in hippocampal neurons destined to die
  426:20, p. 3454 - 3466 2014
• The Journal of neuroscience
  Kaneko Naoki, Hwang Jee-Yeon, Gertner Michael, Pontarelli Fabrizio, Zukin R Suzanne, Casein kinase 1 suppresses activation of REST in insulted hippocampal neurons and halts ischemia-induced neuronal death
  34:17, p. 6030 - 6039 2014
• The Journal of neuroscience
  Sehara Yoshihide, Zukin R. Suzanne, Etgen Anne M., Sawicka Kirsty, Hwang Jee-Yeon, Latuszek-Barrantes Adrianna, Survivin Is a Transcriptional Target of STAT3 Critical to Estradiol Neuroprotection in Global Ischemia
  33:30, p. 12364 - 12374 2013
• Neuropsychopharmacology (New York, N.Y.)
  Hwang Jee-Yeon, Aromolaran Kelly A, Zukin R Suzanne, Epigenetic Mechanisms in Stroke and Epilepsy
  38:1, p. 167 - 182 2013

Grants

• Childhood Disease Research Endowment

• NIH/NIGMS Cognitive Neuroscience of Development and Aging (CoNDA) Administrative Supplement Award: TREM1 as a Novel Therapeutic Target for Global Ischemia Induced Neuroinflammation, Neuronal Death and Cognitive Deficits.

• Health Science Strategic Investment Fund: Biomarkers from brain-derived blood exosomes inhuman patients with Parkinson's disease

• LB692 New Initiatives Research Grant: Epigenetic regulation of neuroinflammation in global cerebral ischemia.

• NIH/NIGMS CoNDA Center Pilot Project Award: Neuroinflammation in neurodegeneration and cognitive impairment associated with global ischemia .

• Dr. George F. Haddix President's Faculty Research Fund: Identification of Biomarkers in CNS-Derived Blood Exosomes in Parkinson's Disease Patients

• LB692 Biomedical Research Development Program: Profiling of altered genes and examining their role in neurodegeneration.

• NIH Exploratory/Developmental Research Grant (R21): Characterization of a novel mouse with deficient calcium flux

• American Heart Association Scientist Development Grant: The role of miR-132 and miR-34 in global ischemia

• NARSAD Young Investigator Award: Polycomb protein-dependent epigenetic remodeling of NMDA receptors as a risk factor in Schizophrenia.