Kenneth L. Kramer, PhD
Kenneth L. Kramer, PhD

Kenneth L. Kramer, PhD

Assistant Professor
School of Medicine

Academic Appointments

Department

  • Biomedical Sciences

Position

  • Assistant Professor

Secondary Appointment

  • Medical Education

Teaching Activity

  • Advanced Cell and Molecular Biology
  • Current Topics in Clinical Anatomy
  • Endocrine/Reproductive System
  • Medical Anatomy (Course Director)
  • Molecular and Cellular Biology
  • Neurosciences
  • Research Methods (Course Co-Director)

Biography

Kenneth L Kramer is an Assistant Professor in both the departments of Biomedical Sciences and Medical Education, reflecting his interests in both research and teaching. After receiving his Ph.D. from the University of Cincinnati in Anatomy and Cell Biology, he did postdoctoral work at the University of Utah and was an investigator at the National Heart, Lung, and Blood Institute. His main area of research is in developmental glycobiology, and he works with numerous undergraduates and several labs at Creighton in focusing on how glycoproteins affect ear and brain development. Ken has a passion for medical education, seeking innovative approaches to teaching anatomy and histology. In addition to being active in the American Association of Anatomists for many years, he enjoys outreach programs to area budding scientists through BioEYES Omaha (a program he created) and Nebraska Science Festival. He serves as a Boy Scout Troop Committee Chairman (Mary Our Queen) and Sacristan (St Stephen the Martyr). Together with his wife of twenty years, Bridget, Ken also supports the many activities of their three children, Sarah, Jack, and Maggie, in various roles at Skutt Catholic High School and the local swimming community.

Education

  • University of Dayton,B.S.,1987-1991
  • University of Cincinnati,Ph.D.,1991-1997

Publications and Presentations

Articles

  • C Inserra and KL Kramer. (2015) Visualization of Stereocilin in the Developing Zebrafish Ear., The Medical Student Press Journal, 2 (2), 2015
  • MV Galanternik, KL Kramer, T Piotrowski.Heparan Sulfate Proteoglycans regulate Fgf signaling, ligand diffusion and cell polarity during collective cell migration, Cell Reports, 10 (3), 414–428, 2015
  • YW Lundberg, Y Xu, KD Thiessen, and KL Kramer. Mechanisms of otoconia and otolith development., Developmental Dynamics, 244 (3), 239-53, 2014
  • B Gorsi, F Liu, X Ma, TJ Chico, A Srinivasan, KL Kramer, E Bridges, R Monteiro, AL Harris, R Patient, and SE Stringer. The heparan sulfate editing enzyme Sulf1 plays a novel role in zebrafish VegfA mediated arterial venous identity., Angiogenesis, 17(1) , 77-91, 2013

Publications

  • Kevin D. Thiessen and Kenneth L. Kramer. Keratan sulfate mediates zebrafish otolith development and growth., Annual Meeting of the Society for Glycobiology, 2013
  • Anne E. James, Kevin D. Thiessen, and Kenneth L. Kramer. Alpha-Tectorin mediates auditory hair cell attachment to zebrafish otoliths., 2013 Central Region IDeA Conference in Kansas City, 2013
  • Anne E. James, Kevin D. Thiessen, and Kenneth L. Kramer. The role of alpha-Tectorin in zebrafish inner ear development., St. Albert's day/Creighton University Research day, 2013
  • Christopher R. DeVries, Kenneth L. Kramer, and Laura L. Bruce. Expression of glypican 3 in homologous amygdala-like regions of diverse vertebrates., St. Albert's day/Creighton University Research day, 2013
  • Kevin D. Thiessen and Kenneth L. Kramer. Keratan sulfate mediates zebrafish otolith development., Annual MidWinter Research Meeting of the Association for research in Otolaryngology, 2013

Presentations

  • B Hassman, E Dorchuck, C Prince, K Reidelberger, KL Kramer, and LL Bruce. (2017). Comparison of behavioral tests to assess fear and anxiety in a teleost, Danio rerio, and an amphibian, Xenopus tropicalis. Poster Presentation at Society for Neuroscience., 2017
  • CJ Altfillisch, DB Nerland, CJ Inserra, MF Chlopek, and KL Kramer. (2017). Stereocilin-b Tethers the Zebrafish Otolith to Sensory Hair Cell in the Inner Ear. Poster at Experimental Biology Annual Meeting., 2017
  • KD Thiessen, LN Higuchi, and KL Kramer. Polyketide Synthase is Required for Zebrafish Otolith Biomineralization. (2017). Poster Presentation at Experimental Biology Annual Meeting., 2017
  • B Hassman, E Dorchuck, KL Kramer, and LL Bruce. (2017). Behavioral Tests for Assessing Learning in Xenopus Tropicalis. Oral Presentation at The Nebraska Academy of Sciences Annual Meeting., 2017
  • CL Harrison and KL Kramer. Characterization of Specific Glycans in the Zebrafish Inner Ear. (2017). Poster Presentation at Creighton Honors Day., 2017
  • SH Byer, LL Bruce, and KL Kramer. Understanding the Role of Amygdalar Proteoglycan Glypican-3 in Zebrafish Aversive Behavior Response. (2017). Poster Presentation at Creighton Honors Day., 2017
  • CJ Altfillisch, DB Nerland, CJ Inserra, MF Chlopek, and KL Kramer. (2017). Stereocilin-b Tethers the Zebrafish Otolith to Sensory Hair Cell in the Inner Ear. Poster Presentation at Creighton’s St Albert’s Day., 2017
  • E Supe, KD Thiessen, and KL Kramer. (2017). Zebrafish as a Model for Benign Paroxysmal Positional Vertigo. Poster Presentation at Creighton’s St Albert’s Day., 2017
  • HJ Lang, and KL Kramer. (2017). Investigation of Enhancers that Drive Specific Expression in the Amygdala. Poster Presentation at Creighton’s St Albert’s Day., 2017
  • CL Harrison and KL Kramer. (2017). Characterization of Specific Glycans in the Zebrafish Inner Ear. Poster Presentation at Creighton’s St Albert’s Day., 2017
  • KD Thiessen, LN Higuchi, and KL Kramer. (2017). Polyketide Synthase is Required for Zebrafish Otolith Biomineralization. Poster Presentation at Midwest Student Biomedical Research Forum., 2017
  • JE Marvin and KL Kramer. (2017). The glycosyltransferase Loki uses a high-energy donor to indirectly transglycosylate methylumbelliferone. Poster at Midwest Student Biomedical Research Forum., 2017
  • JH Werner, KL Kramer, and LL Bruce. (2017). Localizing Homologs of Gene-Specific Amygdalar Neurons in the Chicken Brain, Gallus Gallus Domesticus. Poster at Midwest Student Biomedical Research Forum., 2017
  • CJ Inserra and KL Kramer. Stereocilin Paralogs Have Distinct Roles in Zebrafish Inner Ear Development. Poster Presentation at the Association of Research Otolaryngology Annual Meeting., 2017
  • B Timm, KL Kramer, and LL Bruce. (2016). Localizing homologs of gene specific amygdalar areas in embryonic chick brain Gallus gallus domesticus. Poster Presentation at Annual Biomedical Research Conference for HS-MACA students., 2016
  • "Sugar Balance: How Glycans Control Inner Ear Development", 2016
  • Catharine  N Kral, Benjamin F Kopecky, and Kenneth L Kramer. TECTA, Otog, and Otogl Influence Zebrafish Otolith Organization. Poster Presentation at Creighton Honor’s Day., 2016
  • Catharine  N Kral, Benjamin F Kopecky, and Kenneth L Kramer. TECTA, Otog, and Otogl Influence Zebrafish Otolith Organization. Poster Presentation at St. Albert’s Day., 2016
  • Kevin D Thiessen and Kenneth L Kramer. Role of Otolin-1b During Otolith Nucleation in Zebrafish. Oral Presentation at St. Albert’s Day., 2016
  • KD Thiessen and KL Kramer. The Otolithic Membrane Mediates Otolith Organization. Poster Presentation at Experimental Biology Annual Meeting, 2016
  • C Barta, H Liu, KL Kramer, KW Beisel, DZ He. (2016). Transcriptome Characterization of Adult Zebrafish Inner-Ear Hair Cells. Poster Presentation at the Association of Research Otolaryngology Annual Meeting., 2016
  • EW Villanueva and KL Kramer. Age-Related Changes in the Inner Ear of the Adult Zebrafish. Poster Presentation at Creighton Honor’s Day., 2015
  • C Altfillisch, K Arnold, L Higuchi, KL Kramer, MG Nichols, HC Jensen Smith. Differences in Aminoglycoside Entry and Mitochondrial Metabolism in Regenerative and Non-Regenerative Sensory. Poster Presentation at St. Albert’s Day., 2015
  • K Arnold, C Altfillisch, L Higuchi, KL Kramer, MG Nichols, HC Jensen Smith. Differences in Mitochondrial Metabolism in Regenerative and Non-Regenerative Sensory. Poster Presentation at St. Albert’s Day., 2015
  • KD Thiessen and KL Kramer. Endolymph facilitates otolith nucleation in early zebrafish ear development. Poster Presentation at St. Albert’s Day., 2015
  • CJ Inserra and KL Kramer. Visualization of Stereocilin in the developing zebrafish ear. Poster Presentation at Midwest Student Biomedical Research Forum., 2015
  • KD Thiessen and KL Kramer. Endolymph facilitates otolith nucleation in early zebrafish ear development. Poster Presentation at Midwest Student Biomedical Research Forum., 2015
  • Otolith organization is mediated by otogelin-like. Oral Presentation at the Association of Research Otolaryngology Annual Meeting., 2015
  • "Otogelin in Zebrafish Otolith Attachment and Organization", 2014
  • Seeding zebrafish otoliths: sweet & salty mediators of zebrafish ear development", 2014
  • “From Sweet to salty: mediators of zebrafish ear development”, 2013
  • Development of hearing in zebrafish., 2013
  • Keratan sulfate mediates zebrafish ear development., 2013

Research and Scholarship

Grant Funding Received

  • Role of Kinocilia-Specific Proteins in Zebrafish Vestibular Function. Health Science Strategic Investment Fund.
  • Role of gpc3 in fear behavior. CURAS Faculty Research Fund.
  • Role of Glycosaminoglycans in Zebrafish Development
  • Role of Keratan Sulfate in Zebrafish Ear Development
  • Direct analysis of glycans during zebrafish development
  • ZOIC-Zebrafish in Omaha Inner City Classrooms

Awards and Honors

  • Basic Science Teaching Scholar Award, Creighton University School of Medicine, 2015